Drug info - How to Potentiate the Effects of LSD?

[Nature Boy]

As far as I know the vitamin C trick with mushrooms is a myth. The trip could be intensified by using other drugs with it, powerful stimulants such as MDMA for example. The most sure-fire way to lengthen a trip is to redose LSD a few hours later. That never appeals to SWIM however. He finds LSD trips long enough.

[CrookedEye]

Swim has no scientific evidence to spport the claim, but he seems to experience an intensity in his trip after taking vitamin C (drink of OJ or Hawaiian Punch, for example).. Although the difference is somewhat slight, it definitely seems to make a difference.. Give it a shot, it won't hurt you, either way..

[roserjoe]

SWIM recently heard that magnesium and grape juice are great potentiators for DXM. Although he is not planning on trying DXM any time soon, he was wondering if there are any potentiators for LSD? Apart from cannabis.

[Alfa]

I wouldn't call cannabis a potentiator of LSD. Cannabis does alter the effect of LSD and this altered effect is more intense. But it is not so that the intake of cannabis gives more of the same effect.
I wonder why one would want to potentiate something which is already active in such a low dose? If one would want to increase effects, the LSD user can simply redose or take a higher dose. SWIM finds LSD to be pretty hard core. Not something which needs potentiating.

[Nature Boy]

Monoamine oxidase inhibitors (MAOIs) are capable of potentiating LSD although I wouldn't recommend using them with so powerful a substance. There are many different types of MAOIs, from pharmaceuticals Nardil, Marplan, Emsam etc. to tryptamines with MAOI properties like Banisteriopsis caapi which is often used with ayahuasca.

[zera]

Originally Posted by Nature Boy

Monoamine oxidase inhibitors (MAOIs) are capable of potentiating LSD although I wouldn't recommend using them with so powerful a substance. There are many different types of MAOIs, from pharmaceuticals Nardil, Marplan, Emsam etc. to tryptamines with MAOI properties like Banisteriopsis caapi which is often used with ayahuasca.

As someone mentioned a few months ago, if one was to have DOx blotter instead of LSD taking an MAOI could be major bad news.

On the subject swim found that after almost completely down from LSD, smoking a little salvia produces a crazy trip, but then after the salvia completely wears off the LSD visuals go from being almost gone to back to amazing. Same with mescaline.

Reputation Comments on this post:

good call

[big_mac]

oooo, i got one, do some nitrous oxide, when swim and his buddys did a few baloons they started tripping way harder, and didnt come down 4 a WHILE

[roserjoe]

Ahh ok, SWIM was just wondering if there was anything that might give him a boost when he is peaking. Not to worry though, he wouldn't want to boost to far into a bad trip.

[rodent]

Smoking an extract of syrian rue seeds (or possibly just crushed up seeds themselves) during a trip can give one some fairly intense effects. It's also easier SWIM found to control the intake and therefore the effects of an MAOI with LSD this way.

As said before, you better know that you have LSD and not a DOx before trying this.

[Demonslayer]

SWIM finds tobacco boosts the experience for a short while. But the most effective is sensory deprivation, just sit yourself in bed, fluff up some pillows, turn off the light, lean back and if it isn't quiet enough, stick some earplugs in your ears.

[mr. strawberry]

since we are on the subject, has anyone ever heard that orange juice, or more generally, vitiman C enhances LSD? is there any truth tothat at all? It never seemed to do much for SWIM, but hey it couldnt hurt either and the mind is a very strong tool when tripping and if you believe something enough....

[Jatelka]

^^^ See Here...

http://www.drugs-forum.com/forum/sho...6&postcount=64

[mr. strawberry]

Originally Posted by Jatelka

^^^ See Here...

http://www.drugs-forum.com/forum/sho...6&postcount=64

thanks for the link. good read, and backwards from everything i was told as a teen. I was wrongfully informed that vitamin C would increse the trip and if one wanted to decrease it B12 would help a little (thus there was never any b12 consumed the day of the trip) but some people (not me) would always carry a bottle of b12 pills in case things ever got out of hand (swim never once had a sober sitter and in fact didnt like to be around sober people while tripping...yet lives to tell about it lol)

[Nagognog2]

Smoking DMT, or 5-MeO-DMT, at the peak of an LSD trip can send the person into another dimension. No cross-tolerance between DMT et al and LSD has been found. Or it's too minimal to note.

[podge]

A natural adrenaline rush would intensify the trip swim would imagine......go skydiving , walk on hot coals , throw eggs at dangerous people and run for your life.....right , none of these are a good idea while tripping but it sure would get intense. Maybe if swiy can find a safe way to get a natural adrenaline rush then it would work. But like alfa said , the best way to get an LSD trip to reach the next level is to drop more at a time.

[chAos]

Originally Posted by podge

A natural adrenaline rush would intensify the trip swim would imagine......go skydiving , walk on hot coals , throw eggs at dangerous people and run for your life.....right , none of these are a good idea while tripping but it sure would get intense. Maybe if swiy can find a safe way to get a natural adrenaline rush then it would work. But like alfa said , the best way to get an LSD trip to reach the next level is to drop more at a time.

Actually if swim recalls it correctly an adrelaline rush will decrease the effects of lsd.

[podge]

Originally Posted by chAos

Actually if swim recalls it correctly an adrelaline rush will decrease the effects of lsd.

Interesting.....so an adrenaline shot would be usefal to terminate a trip or at least take the edge off ?

[boylizard]

Originally Posted by podge

Interesting.....so an adrenaline shot would be usefal to terminate a trip or at least take the edge off ?

to take the edge off? not by a longshot - it still increases mental activity, with the fight or flight response sort of.. well, dependent on adrenaline. id suggest risperdal or thorazine for that purpose.

I haven't heard of any lsd potentiators, other than the obvious more lsd.

[fromthestars]

i wouldnt recommend it personally but try taking some 5-htp for a few days then some lsd. for me anyways it made 1 hit of normally week acid send me to the closest i would call a bad trip yet.

[Jatelka]

fromthestars: Before proceeding further you must READ THE RULES. They are here...

http://www.drugs-forum.com/forum/misc.php?do=cfrules

Do NOT incriminate yourself. Use SWIM (Someone Who Isn't Me) when discussing extra curricular activities. Please`bera in mind that not abiding by the rules here can and WILL get SWIY banned. Thankyou

[seechao]

SWIM has tried 5-htp before acid, and it does seem to have a bit of a happier feel to it, but that may be psychosomatic, it does pottentiate mdma quite well however.
SWIM has also had a bit of experiance with syrian rue and lsd, which is amazing, but very very intense and long lasting, good for spiritual work, but a bit much for entertainment. Nitrous has always been one of SWIM's favorite trip boosters, seems to work with any psychedelic, boosts the visuals, makes you happy and blissfull, its wonderfull. Marijuana only potentiates lsd if your tollerance is low enough, and it does wonderfull things to it, but it tends to make you slow/stupid. SWIM recently smoked a DMT laced joint while tripping, and had a very strange, but beautifull experiance with it, maybe 60mg of DMT was disolved in methanol and redeposited onto the mj... best joint SWIM ever smoked
SWIM has recently been playing with meditation, and found that opening your root and sending energy to the crown or third eye make for some amazing intense experiance, even sitting and playing with your energy with eyes closed usualy leads to a much more powerfull trip, SWIM gets warm flushes of energy flowing thru him that are very pleasant, and a definite increase in visuals, also, a reduction in negative side effects.

[The Wizard]

I had a dream recently where an elf listed for me some cheap effective methods for potentiating tryamine (such as L) trips:

First I'll list substances the elf said to preload on days before a trip:

One can take very high doses of Melatonin (an OTC health supplement pill sold at pharmacies/groceries) nightly starting a week before a trip. Start with 3 mg a night and work your way slowly up to 12+ mg a night. By the time you decide to trip (no Melatonin the night of the trip) you should get stronger, longer lasting effects. The elf has personally tried the Melatonin preloading to success.

5-HTP (a Serotonin boosting OTC drug) may also work as a health supplement to preload on nightly for a week before tripping. Try taking 100-200 mg of 5-HTP a day divided into one daytime dose and one nighttime dose. You may find it makes you too drowsy during the day so in that case only take it at night. You should also take Vitamin B6 with your 5-HTP as it helps your body absorb it. Hopefully the night your trip your brain will have lots of extra Serotonin floating around which will potentiate your trip.

The last substance the elf recommended you preload on starting a week before your trip is the smart drug, Piracetam. Piracetam is a stimulating, intelligence boosting drug which can be ordered cheaply and easily online. The elf recommends you start taking 7-10 grams of Piracetam spread out into a few doses a day a week in advance of the trip. If one wants they can take even more a day as Piracetam is extremely safe and healthy. The closer you get to your trip if you so choose you can lower your dose of Piracetam a bit as your body is becoming more and more sensitive to it as it builds up in your system. The elf said he has tried Piracetam and it does boost his trips.

Some substances one can take the day of the trip hours before it to enhance
it. One such drug that may theoretically work is Grapefruit juice (supposedly White Grapefruit juice is the most potent not Ruby Red). More and more people on forums have suggested that filling your system with glasses and glasses of GFJ the day of your trip may potentiate it and make it healthier. GFJ preloading has been proven to boost DXM, some benzos, opiates and amphetamines. The elf said every 30 mins or hour drink at least 1 12 oz. glass of GFJ the day of your trip. He starts drinking the GFJ 6-12 hrs in advance of his trip as the more hours youve been saturating your system with the GFJ the better it will synergize with your trip.

Another substance one can take starting a few hours or even days before a trip is Deprenyl. It is an MAO-B inhibitor and MAO's theoretically boost and lengthen Tryptamine trips. If you start taking Deprenyl daily days in advance (5-10 milligrams a day) it will slowly build in your system giving you the best chance of it boosting your trip. At the very least take a few divided doses of Deprenyl the day of your trip.

MAOI's also theoretically may boost a trip Tryptamine trip (the combo of an MAOI and tryptamine is known as "Huasca"). However, this may be physically risky as MAOI's can have many potentially harmful interactions if you take too high a dose of them or are on the wrong food/drug diet. A popular MAOI that people use on forums before tripping is Syrian Rue. The Caapi vine is another good source of MAOI's. These plants the elf warns you taste HORRIBLE can can cause very strong nausea. However, if you make them into a concentrated resin (resin recipes are in the Syrian Rue vault on Erowid) you have less chance of nausea. Another advantage of the resin is it can be smoked. If you don't feel like doing this at the very least grind your Rue up finely and pack in capsules and swallow it a few hours before your trip on a relatively empty stomach. Take no more than 4 or 5 grams of Rue, maybe even less. Another MAOI substance which may be a safer choice is the prescription drug Moclobemide.

Lastly, the elf mentioned there are a number of substances people commonly take either right before a trip or during it. He said you people likely already know of these though- MJ, E/Mescaline, Nitrous, DXM/K, opiates, Kratom.

The elf told me to wish you people good luck on your journeys.

Reputation Comments on this post:

No links to commercial sites

[Heretic.Ape.]

^ Nice informative post. MAOI's are probably not a good idea as they can be unsafe (as mentioned) and studies have shown them to actually diminish response to lsd (although they can potentiate other tryptamines). You may want to edit out the commercial site (for Piracetam). Thanks.
h.a.

[The Wizard]

I am pretty confused at the conflicting reports online about the interactions between LSD and MAOI's. I too have read many sourches that say that MAOI's weaken LSD, however, at the same time there's numerous experiences online of people who've used Syrian Rue with LSD and insist it potentiated their trip. My elf friend used 5 grams of Rue an hour or 2 before an L journey and he too found it seemed to enhance the effects. It produced more of a mellow stoning feeling. He also did not feel like the Rue made his trip any more toxic feeling. So what would make Rue different than other MAOI's?

Two potentiators I failed to mention earlier which the elf discussed with me are Tricyclics and Lithium. The idea that Tricyclics would potentiate a trip baffles me because I thought they had a sedating effect (such as Elavil)? However, I've noticed there's a new novel tricyclic drug called Amineptine which is said to have a very speedy effect.

As far as the Lithium the elf strongly warned NOT to be foolish enough to take it before or during a trip as the combo has been known to cause seizures (as is evidenced by numerous experience reports on Erowid).

[radiometer]

LSD is a receptor slut. There is no need to potentiate it. Is the idea here to take a very safe drug and try to make it more dangerous?

From what I understand, LSD is a poor substrate for MAO in the first place, so any effect from MAOIs would be additive, not potentiation. I find the idea that MAOIs decrease the efficacy of LSD to be difficult to swallow (yes, I have seen the sources of this theory, I just don't quite buy it).

Also, re: Deprenyl and MAO-B - MAO-B is mostly involved with the metabolism of phenethylamines, not tryptamines, which are mostly dealt with via MAO-A. There is some crossover, but that's the general rule.