Combinations - Diphenhydramine potentiation using grapefruit juice

[RaverHippie]

After looking through the forum I was wondering if anyone had tried to combine grapefruit juice, known for requiring liver enzymes for metabolism, with diphenhydramine since in other threads it has been covered that diphenhydramine also requires the same liver enzymes.* Anyone with specific experiences? Even though the main enzymes aren't utilized by both substances I was wondering if any qualitative effects have been noticed.
A lab rat has made his opinion known that he would be willing to volunteer for experiments.

Thanks

*here's my sources

Originally Posted by Jatelka

Diphenydramine is metabolised by the liver. CYP2D6 has the greatest activity. CYP1A2, CYP2C9, and CYP2C19 are also involved, but to a much lesser extent.

Originally Posted by wikipedia

Compounds in the juice... affect the activity of certain intestinal enzymes including CYP3A4 and CYP1A2.

[Orchid_Suspiria]

Diphenhydramine is a drug that doesn't really need potentating but if swiy really wants to give it a try swim says be careful!