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Piperazines Piperazines and piperazine containing party products.

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  #1  
Old 27-01-2005, 11:19
lociel lociel is offline
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2,5-dimethoxy-4-bromobenzylpiperazine



Has anyone information about "2,5-dimethoxy-4-bromobenzylpiperazine"?


it's similar 2C-B, and orally dosage range 50-75mg.
only it that i know.
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  #2  
Old 27-01-2005, 18:17
anj0vis Gold member anj0vis is offline
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I'm interested but never seen this. Where did you get this information?
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  #3  
Old 28-01-2005, 20:43
lociel lociel is offline
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This substance is information from Chemical supplier.
It seems to have sent it to some customers though it did not sell in general.
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  #4  
Old 27-02-2005, 03:20
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This substance is information from Chemical supplier


I very much doubt it's anything like 2C-B as it is simply the 'wrong' shape to bind to the 5HT2a receptor (which is responsible for the activity of the 2C's-DOx compounds). You need independant info as to it's effects before even thinking of believing a RC vendors hype
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  #5  
Old 01-03-2005, 22:52
moeBius Gold member moeBius is offline
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i asked a vendor about more informations, here is his answer:



Quote:
1-(2,5-dimethoxy-4-bromo)benzyl-1,4-diazacyclohexane (the


benzylpiperazine analogue of 2cb) is a novel compound; it has some


popularity in New Zealand and South Africa. I do not have


additional info on it, other than it has some stimulating and


possibly other central effects.


never heard that this compund gained popularity anywhere and afaik they sell only bzp and tfmpp in new zealand.


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  #6  
Old 02-03-2005, 23:22
blackwolf blackwolf is offline
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Yea......that sounds kinda shady if you ask me. It could possible
work....but then again as F&B said, it doesnt look to be the right shape to
fit into the receptor right. I would ask for a small sample before making a
bigger purchase.
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  #7  
Old 08-04-2005, 21:00
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is 1-(2,5-dimethoxy-4-bromo)benzyl-1,4-diazacyclohexane????is it active??
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Old 09-04-2005, 03:34
Labrat Labrat is offline
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That is just some misfits feeble attempt to describe this piperazine: 1-(4-bromo-2,5-dimethoxybenzyl)piperazine, which is the 2C-B version of BzP, a.k.a A2. There is nothing, nothing suggesting that it has any sort of pleasant or interesting activity. The structure-activity relationship of phenethylamines isn't applicable to benzyl- or phenylpiperazines. If some RC-vendor tries to tell you otherwise he's lying.


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Old 11-04-2005, 16:58
Dimitri Gold member Dimitri is offline
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Quote:
If some RC-vendor tries to tell you otherwise he's lying.
I also bought some of this substance due to the fact that it is really
cheap & my curiosity...I didn't get it from an RC-vendor, but
probably the person I bought it from. I was told, that it is definitly
active & should have stimulating as well as psychotomimetic
effects. Although the chemical structure is not correct to fit the
right place in brain .

I didn't try it
yet. I found this other thread, maybe that is a help with a dosage:





Edited by: Dimitri

Last edited by Alfa; 28-07-2009 at 05:27. Reason: dead link
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  #10  
Old 17-04-2005, 09:06
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sounds like a dirty ass version of 2C-B, bound to be active but the piperazine side effects profile makes for a pass on this one
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  #11  
Old 25-04-2005, 00:00
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Well i've tested this substance at 10, 20 and 60mg. Some stimulation at 60mg but barely noticeable buti will be experimenting further soon. I have read a recent trip report from a dutch site (i don't speak dutch and babelfish is shitty at dutch ) in which atripper used 120mg and then another 120mgsome hours later without any problems, think i'll push up the dose to 150mg next time. Oh and i've got a headache...
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Old 26-04-2005, 05:28
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>Iggypop


thanks your post.
i expect your following report.
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  #13  
Old 26-04-2005, 10:53
Dimitri Gold member Dimitri is offline
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A friend of mine recently tested it with just about 20 or 30mgs. But he
eyedosed it by licking out the baggie, so that is not very reliable. As
he told me he definitely got some treshold effect from it already in
that low dosage. I post here, as soon as I get some more reports from
him.
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  #14  
Old 26-09-2008, 00:10
dr.qil dr.qil is offline
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Re: 2,5-dimethoxy-4-bromobenzylpiperazine

Quote:
Originally Posted by Dimitri View Post
A friend of mine recently tested it with just about 20 or 30mgs. But he
eyedosed it by licking out the baggie, so that is not very reliable. As
he told me he definitely got some treshold effect from it already in
that low dosage. I post here, as soon as I get some more reports from
him.
From the little knowledge I have on the subject I have witnessed subjects consume up to 60 to 75 mgs but found it to be of little to no effect solitary however this amount compounded with MDMA seemed to produce a hallucinogenic effect. Also it was noted on one occasion that only a small amount was imbide through the same means as above stated in quotation and the same effects were also noted approx 15-20mgs we're imbided/ saturated thro the skin. Anyone with similar data please share???
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  #15  
Old 26-04-2005, 23:55
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Yeah i had taken it around that sort of dose and thought i had threshold sorta dose but i think it was more the 'this is untested' placebo effect. I'll be doing it at a higher dose soon, i'll let you know how it goes. There'll be a trip report on it.
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Old 01-05-2005, 20:00
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I think this one is bunk.


My primate has taken up to100 mgs of this stuff with very little result.


May be my primates body chemistry is funny with this stuffor had gotten a bad batch. (From a good vendor)


If you are experiementing tho'...start low. This is a compound with very little info about it. Don't startat the 100 mgs where I left off please!
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  #17  
Old 11-03-2006, 05:28
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Has anyone found an active dose, or indeed any worthwhile acticity with this one?
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  #18  
Old 20-03-2006, 15:10
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No worthwile activity noted at any dosage up to 150mg. Methinks that this was a marketing ploy to sell the *2c-b* branding.

I wouldn't bother even if i could get it anymore.
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Old 21-03-2006, 14:18
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Thanks for the reply. Shame. I have read that PEA analogues don't apply with piperazines which are genarally considered rough anyway. One comment I recall was that 2CB-BZP was "worth its weight in shit." Maybe it has no activity at all.
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Old 14-02-2007, 02:42
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Re: 2,5-dimethoxy-4-bromobenzylpiperazine

that's not much shit considering how big is a bzp dose...ok, stupid comment
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Old 29-09-2008, 06:11
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Re: 2,5-dimethoxy-4-bromobenzylpiperazine

From the wiki:

2C-B-BZP

From Wikipedia, the free encyclopedia

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This article does not cite any references or sources.
Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged and removed. (December 2007) 2C-B-BZP
Systematic (IUPAC) name 1-(4-bromo-2,5-dimethoxybenzyl)piperazine Identifiers CAS number ? ATC code ? PubChem ? Chemical data Formula C13H19BrN2O2 Mol. mass 315.2085 g/mol SMILES eMolecules & PubChem Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ?
Legal status
Routes ? 2C-B-BZP is a research chemical and stimulant of the piperazine family.

[top]Contents


[hide]

[edit] Chemistry

2C-B-BZP is 4-bromo-2,5-dimethoxy-benzylpiperazine. It is related to BZP and shares the ring-substitution pattern of the psychedelic phenethylamine 2C-B, although 2C-B-BZP is not a phenethylamine itself.

[edit] Dosage

Reported doses are mainly in the 100-200 mg range.

[edit] Effects


This section does not cite any references or sources.
Please help improve this section by adding citations to reliable sources. Unverifiable material may be challenged and removed. (June 2008) 2C-B-BZP produces dose-time-dependent stimulant effects[ambiguous] lasting 3-6 hours. Despite its structural similarity to 2C-B it does not produce psychedelic effects as the binding groups are in the wrong position to activate the 5HT2A receptor. 2C-B-BZP is also said by several sources to increase the effects of other compounds when combined. Side effects include headaches and nausea, similar to other piperazine derivatives used recreationally.

[edit] Legality

2C-B-BZP is unscheduled and uncontrolled in the United States, but possession and sales of 2C-B-BZP could possibly be prosecuted under the Federal Analog Act because of its structural similarities to 2C-B or BZP. 2C-B-BZP is said to be illegal to possess, use or sale in Japan where it used to be sold in local smartshops.

[edit] Pharmacology

The pharmacology of 2C-B-BZP is unknown.

[edit] Dangers

The toxicity of 2C-B-BZP is not known, although benzylpiperazine (BZP), which is chemically related, has known toxicity.

[edit] Popularity

2C-B-BZP is unknown on the black market, though it is available from research chemical vendors that operate on the internet. It is more common in South Africa than Europe and North America.
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