Ibogaine for Opiate Addiction- experiences and info

[Alfa]

IBOGAINE
EXPLORING THE NEW FRONTIER OF PSYCHEDELIC ADDICTION THERAPY
Ray slips his shades back over his eyes and leans against the window as the van crosses the border into Mexico. It's noon on Monday, Oct.
31, and he hasn't slept in three days. He thinks about the bag of chronic he threw out the window on the way to meet the guy from the clinic. He thinks about the pipe load of meth stashed in the seat of his motorcycle back home. Ray is skeptical--will he really be so changed by Friday that he'll be able to go home and throw it away?
Ray is a 33-year-old meth producer, dealer and addict. So far, Ray's missing fingerprints are the only physical evidence of his addiction--they gradually peeled off after repeated contact with so many chemicals.
Six months ago, after a stint in prison and more than two years clean, he relapsed and took a leave of absence from refrigerator-repair school "to go run amok." The past few months, says Ray, "have been out of control . I won't do anything unless I smoke first. I feel like I just have to do it."
He's afraid that either death or jail is imminent if he doesn't change his life.
"I find myself doing stuff that I would never even do normally," Ray says. "I have a pocket full of money, but I'm out there robbing warehouses and things--Target warehouses, Wal-Mart--just to do something. I've got $2,300 in my pocket and I'm sitting there trying to break into a Coke machine at the Embassy Suites."
Reluctant to quit partying but desperate to curb his destructive behavior, Ray is traveling to the Ibogaine Association, a Tijuana clinic originally founded in Mexico City that treats patients with a powerful psychedelic--ibogaine--rumored to be able to stop addiction in its tracks. Legally accepted as an experimental therapy in most countries, ibogaine is classified as a Schedule 1 substance in the United States, believed to have a high potential for abuse with no accepted medical value.
Every Monday, program director Nathen Gabriel meets new patients at Urban Grind, a cafe located just north of Balboa Park, and shuttles them to the clinic, where they stay until he picks them up Friday morning.
Program director since March 2005, Gabriel has a background in psychedelic healing and a doctorate in naturopathic medicine. He's a lean, compact man in his early 40s with a gaunt face and large eyes that seem to take everything seriously. He looks like a mystic only from the neck up, where an elaborate tattoo of serpents twining around a lotus flower crowns his shaved head and creates the illusion of a third eye at the base of his skull.
Though he's worked at the clinic less than a year, Gabriel's talent for the job emerges during the 30-minute drive. He's friendly and sincere with each patient, asks them straightforward questions about their addictions and absorbs their answers without judgment. They invariably ask questions about ibogaine, and when they do, excitement creeps into his responses.
He explains that ibogaine comes from the root bark of Tabernathe Iboga, a shrub that grows in Central Africa, and has been used for centuries in various ceremonies of the Bwiti tribe.
A man named Howard Lotsof, Gabriel says, took ibogaine in 1962 as a 19-year-old junkie chasing a new thrill. After enduring 36 hours of harrowing visions, Lotsof awoke to find he had no desire to use heroin and was totally free from any symptoms of withdrawal. He has spent the rest of his life trying to make ibogaine more readily available for those in need.
Gabriel himself has taken ibogaine twice, he says--once to better relate to his patients and again recently in an attempt to curb his pot habit. Gabriel describes his own personal experience of ibogaine as "completely hellish" but hastily adds that everyone experiences it differently.
Before leaving San Diego, Gabriel stops the van at a downtown Days Inn to pick up another patient. Ted is in his early-50s, has red hair and a red beard and wears a faded blue-gray polo shirt, green shorts and athletic socks under Birkenstock sandals. He's been on Vicodin for seven years to treat his chronic neck pain--a result of getting hit by a car while crossing the street 10 years ago--and currently takes 15 to 20 pills every day. He wants to stop and has tried to quit cold turkey "numerous times" but finds it "physically impossible."
Though he's emphatic that the pain he now experiences is from Vicodin withdrawal and not from his injury, he hopes that at the very least ibogaine will reset his tolerance to the Vicodin, enabling him to once again get full relief from a couple of pain pills instead of 20.
Preston Peet, a 38-year-old New York writer, told CityBeat in a phone interview that he uses ibogaine for just that. Ever since a car accident 24 years ago, Peet says he has suffered from chronic pain in his back and legs. Until he took ibogaine for the first time in 2004, he took four MS-Contins (a morphine-based pain killer) and more than
12 Dilaudids every day for the pain. He'll live with chronic pain for the rest of his life, he says, but periodic boosters of ibogaine enable him to keep his painkiller intake down to a mere two MS-Contins per day.
The van arrives at the clinic--a nondescript house in Tijuana's most affluent residential neighborhood--shortly after noon. On the inside, the four-bedroom house looks more like a travelers' hostel than a medical clinic. The only medical equipment in sight is a heart-rate monitor on the nightstand next to each bed. The walls are sparsely decorated, the furniture secondhand, and paisley tapestries are draped over the couches. It was once a grand house, full of high ceilings, chandeliers and pink marble. The contrast gives it a haunting air of abandoned opulence.
Gabriel shows Ted and Ray upstairs to their rooms. In turn, they submit to a blood test, which will be taken to a lab for analysis before they take the ibogaine later that night. Gabriel collects the $4,000 fee before their blood is drawn, and a staff member searches their bags for drugs. At no point does anyone search the patients or their pockets.
When Ted's wife calls on his cell phone, Ray goes out on the balcony for a cigarette.
He leans against the railing and smokes pensively.
Hundreds of cigarette butts have collected on the ledge beneath, a reminder that so many people before Ray have stood smoking on that same balcony, all probably pondering ibogaine's power to change them for good.
Greg Douglass, a musician and recovered heroin addict who's been clean since he took ibogaine in 2003, told CityBeat that the visions he experienced with ibogaine were what changed him the most.
"The whole time I was hallucinating, I didn't feel like I was hallucinating," says Douglass. "I felt like I was being shown something for a reason. All of a sudden it was right there for me to see it's really marvelous to be on this planet and part of this universe. Why didn't I see that before? And all of a sudden it was like this big black hole got filled in."
But Ray is skeptical that he will have a psycho-spiritual epiphany with ibogaine.
"I never saw no ray of light when I was sober," he says matter-of-factly. He gloomily predicts the ibogaine won't work and he'll end up being "burned four grand."
Ray perks up when he remembers that he still gets to trip out one last time before he's supposed to turn his life around.
"I want to fry," Ray says smiling, his eyes lighting up. "Let's do it."
Although Ted and Ray are eager to get the treatment underway, hours remain before the blood tests come back. To kill time and give them a better picture of what they're about to experience, Gabriel shows a documentary about ibogaine called "Ibogaine--Right of Passage."
Before it ends, Gabriel leaves Ray and Ted in the hands of the medical staff. Gabriel, whose role is more administrative than medical, won't see either of them until he returns on Friday to pick them up and take them back to San Diego.
Ever since his discovery, Lotsof has reportedly endeavored to make ibogaine legitimate in Western medicine. He quickly passed some out to his junkie friends for more informal testing, but things got complicated in 1970 when the American government cracked down on psychedelics, making ibogaine illegal along with LSD and psilocybin.
Lotsof gained some ground in the mid-'80s when he obtained patents for the use of ibogaine to treat symptoms of multi-drug dependence, but they were never picked up by any pharmaceutical companies and have recently expired.
Nevertheless, since ibogaine remains legal in most other countries, a scattering of informal clinics like the Ibogaine Association have emerged as testimonies spread through personal networks and--more recently--over the Internet.
When Gabriel returns Friday morning, Ray and Ted await him anxiously at the kitchen table. They giggle conspiratorially like two schoolboys who've bonded during a week at summer camp, cracking jokes about the stray dogs outside and the boredom of their post-ibogaine confinement.
There is more color in Ray's face, and he appears physically illuminated from within. He smiles in spite of himself, and his eyes sparkle. But despite the obvious improvement in Ray's appearance, he says he's not sure how effective the treatment was. He says he's feeling good without meth and plans to get rid of the pipe in the motorcycle, but he says he'll probably keep smoking weed. He is disappointed that he didn't experience any visions.
"Everything is just alright," he shrugs. "I still didn't see no ray of light."
Back on the road to San Diego, Ray's quiet until someone on a motorcycle zooms ahead of the van. His eyes light up all over again.
"That's what I want to do," he says, "go for a ride."
The change in Ted is different. No longer in a Vicodin haze, by Friday morning he's grouchy and cursing. He rubs his shoulder repeatedly through the neck of his T-shirt but says the pain he's feeling now is from Wednesday night's overzealous Thai massage.
Still, he's full of praise for the medical staff and leaves a hefty tip for the night nurses.
His hallucinations were much more memorable than Ray's.
"I saw myself in the Civil War," Ted tells Gabriel on the ride back to San Diego. "There were themes of honor and courage," he continues.
"I got stabbed in the back by someone with a bayonet, but I didn't feel fear." So far he doesn't regret his decision to come, he says, but isn't sure he would want to take ibogaine again.
A week after his return, Ted reflects on his experience with a much more optimistic tone.
Now that he isn't living through a mix of pain and Vicodin, Ted says, his biggest pleasure has been spending more time with his children.
"I'm really hoping the effects stay around for awhile," Ted concludes. "It does feel like my life's better because of it."
Despite the fact that most addiction specialists today seem to regard psychedelic addiction therapy as a bygone fancy of Timothy Leary and his ilk, a small community of researchers still strives to find a place for ibogaine in mainstream medicine.
Dr. Stanley Glick, chairman of the department of pharmacology and neuroscience at the Albany Medical Institute, has been studying the effects of ibogaine in drug-addicted rats since the late 1980s.
Though he's published data that confirms ibogaine's ability to block opiate withdrawal and cravings in animals, initiating clinical research on ibogaine in humans has been trickier.
Though the FDA approved initial stages of clinical research on ibogaine in humans in 1993, protocol was still being developed for the studies when the National Institute on Drug Abuse (NIDA) pulled its funding in 1995.
Frank Vocci, director of the Division of Pharmacotherapies and Medical Consequences of Drug Abuse at NIDA, says NIDA's review panel made the decision not to go forward with the research based on evidence that ibogaine was a neurotoxin in rats and posed other potential health risks like bradychardia (slowed heart rate) and grand mal seizures.
That much of the data NIDA reviewed of ibogaine's effect on humans came from observations of informal treatment in the Netherlands, rather than clinical research that had passed through peer review, seems to have added to the medical establishment's already disdainful view of psychedelic therapy.
"I think that we need some published data on ibogaine," said Vocci in a phone interview. "That's where I really think this whole issue is, in terms of both safety, metabolism and possible effects."
However, ibogaine supporters like Patrick Kroupa, a heroin addict for
16 years who recovered with ibogaine and now runs an online discussion board called the Ibogaine List, believe ibogaine will never make it out of Schedule 1 status because pharmaceutical companies--some of whom have representatives on the NIDA review board--don't see big dollars in the development of a one-time-use drug for a stigmatized population, especially a drug that has known hallucinogenic side effects.
"The pharmaceutical industry exists for one purpose: to make money for their shareholders," Kroupa said in a phone interview. "There is no pharmaceutical company that could even recover the money it would have to spend to get [ibogaine] through the FDA."
"To take a drug through the FDA is very expensive," confirms Dr.
Deborah Mash, a professor of neurology and pharmacotherapy at the University of Miami who responded to NIDA's withdrawal of financial support in 1996 by moving her human research on ibogaine to a facility in the Caribbean. She published her first batch of data in 2000 and then went back to work collecting more evidence.
"The data that was collected from there supports the development track that we're trying to do with the FDA here," says Mash. "I'm getting ready now to re-convene the clinical studies in the U.S."
However, until she does, it seems there won't be any shortage of people desperate enough for relief to cross national borders for ibogaine treatment.
The Monday after Ray and Ted's visit to the clinic, three new patients meet Gabriel at the cafe. This time, they're all there because of heroin.
One of the men changes his pants behind a dumpster as the other two pile into the van. The vibe among the patients is considerably different, but Gabriel's approach doesn't change. He remains unswervingly calm and again seems at once respectful and intrigued by his patients' take on their addictions.
Joe Alex is 51, Hispanic and has a droopy graying moustache. When his withdrawals cause him to sweat, he peels off his sweatshirt to reveal an upper body covered almost entirely in tattoos. He is the oldest of the three passengers but by far the most upbeat. He calls Gabriel "doc" and engages him in friendly conversation.
He says casually that he's used heroin on and off since he was 18, when he started "out of curiosity." He's been in and out of jail many times since, with one four-year sober stretch, during which he became a certified substance-abuse counselor. He says he enjoyed the work and that people told him he was good at it. But he relapsed when he stopped counseling to take part in a family real-estate venture.
"I've stopped a thousand times," he says good-naturedly. "The problem is staying stopped."
He proves his point as he counts aloud the different times and ways he's detoxed: cold turkey "about a dozen times," in the hospital "about two dozen times," four or five times in Christian homes and six or so times in secular facilities.
He says he hopes he can find his passion, something that will give him something else in life to look forward to.
"I got a Harley I'm passionate about," he adds, "but I can only keep it clean so much."
Josh is a former heroin addict currently on methadone, and at 32 is the youngest patient in the past two weeks. He is white and tall, has short brown hair, wears jeans and a green hoodie and carries James Frey's recovery "memoir" A Million Little Pieces. His skin is yellowish and sallow, and the color of his lips span the spectrum from green to purple. There are dark circles around his eyes and he leans listlessly against the window in the same seat Ray occupied just a week before. He's shy, and his story emerges haltingly. "A bad roommate" introduced him to heroin nine years ago.
"Six months later, I realized I was in trouble," he recalls. "The whole time I was doing heroin I wanted to stop."
He used heroin for four years straight, got clean for three years, but a year ago "a bad breakup" sent him back to the needle. He transitioned to methadone four months ago but is ready to get off it so he can go back to school for shoe design.
It turns out Josh has already been working through a recovery program. He goes to group and individual therapy on a weekly basis and feels like he's already worked through a lot of the "psychological stuff" that caused his addiction. He isn't looking for a spiritual awakening with ibogaine, he says--he just wants a fast, easy way to detox off the methadone.
The third man in the van, Jesus, like Joe Alex, has been using drugs since he was in his teens.
"I know why I use--I grew up around it," Jesus says bluntly. "My brother did it, and I wanted to be like my brother."
Jesus has a jet-black moustache and wears black jeans, a gray sweatshirt, a baseball cap and a dog tag around his neck that says "father of a soldier." He has spent 18 of his 41 years in jail, makes not-so-veiled references about gang involvement and is clearly terrified of ibogaine. His watery eyes--a common sign of early opiate withdrawal--dart back and forth around the van like those of a caged animal. He confesses he almost ran away from the van when it stopped at the bank but couldn't reach anyone from the pay phone. He dominates the conversation in the van, another question pouring out of him while Gabriel is still answering the one before. He's had bad acid trips before, he says--is this one going to be like that? He's going to break parole when he crosses the border--what about that?
What if they get the blood tests back and find out he can't take the ibogaine--what will they do for him then? He has overdosed before and his heart has stopped--could that happen again?
Gabriel patiently and repeatedly tries to calm him, but with marginal success.
At the clinic, Jesus chain-smokes on the downstairs patio. His withdrawal symptoms continue to worsen, and even though he is afraid of the ibogaine trip, he tries to persuade Gabriel to let him take it sooner. Instead, Gabriel shows them the ibogaine documentary, hoping it will distract Jesus and help calm his nerves. He wishes them all well--just like last week, he won't see them again until Friday.
By the time the acupuncturist arrives on Wednesday night, Jesus is already long gone. According to Gabriel, who was contacted by phone in the middle of the night on Monday by one of the night nurses, Jesus remained agitated even after they gave him the ibogaine and was ultimately sent home when he became disruptive toward the other patients.
"Dr. Paula," who gave Jesus his capsule of ibogaine, said at the time that she personally saw him put it in his mouth.
But the fact that Jesus was active and mobile a few hours after pill was given--highly unusual for someone under the effects of ibogaine--compounded with his vocalized fear of having a bad trip, suggests to Gabriel that Jesus never actually ingested any ibogaine.
Jesus' own account is quite different. A few days later, over the phone from his home, he says he did take the ibogaine but could still feel painful symptoms of his withdrawal and wanted more drugs to knock him out. When the night nurses wouldn't give him any, he demanded that they call Gabriel. Once he realized Gabriel was not coming to his aid, Jesus tried to roust Joe Alex, who he believed had methadone. It was around this time that Gabriel instructed the night staff to call a taxi and get Jesus out of the house.
"He treated me with indifference," Jesus says of Gabriel. "He should have come down, or sent Dr. Paula. His solution was to put me in a taxi and send me on my way."
Jesus took the taxi all the way home to San Bernardino; his family had to pay for the $300 ride.
"My family didn't believe in this shit--nobody believed," Jesus says angrily. "The next thing they see is I'm looking to them to cop some dope. That was so difficult. It was just disappointing."
It turns out Jesus' fear of ibogaine may have been more than paranoia. On Jan. 31, a man named Jason Sears died at the Ibogaine Association while receiving treatment for his heroin addiction.
Nineteen hours after Sears ingested the ibogaine, his heart monitor sounded, alerting the staff. Gasping for air in the arms of the doctor, Sears died of pulmonary thrombosis, which is the end result of a blood clot that forms in the body over time and eventually travels to the lungs.
Like all the patients who come through the Ibogaine Association, Sears' heart and liver functions were checked for abnormalities before he was given the ibogaine, says Dr. Medina, who treated Sears at the Tijuana clinic and prefers his first name not be used.
"Evidence shows that ibogaine can slow the pulse of the heart, so it's a red flag when you have a patient with previous heart disease or rhythm abnormalities," Medina explains. "That's why we do an EKG prior to the administration of the ibogaine. He had a perfectly normal heart . His liver enzymes were completely normal."
Though Sears wasn't technically killed by ibogaine, there have been a handful of fatalities reported during informal ibogaine treatments worldwide over the past two decades, none of which have been good publicity for the drug.
Mash, who collects her data in a traditional clinical facility with much more extensive medical scrutiny, is afraid her work will eventually be derailed by such ibogaine-related fatalities.
"I get concerned the more dead bodies we have," she says. "And at some point the door is going to shut tight forever because of this behavior."
However, many ibogaine supporters don't seem overly worried about standards of care at the smaller, informal clinics.
"With all due respect to her opinion," says Kenneth Alper, associate professor of psychiatry and neurology at New York University and co-author of A Contemporary History of Ibogaine in the United States and Europe, "my approach is simply to appreciate the fact that they exist."
In contrast to Jesus, Josh and Joe Alex experience ibogaine without incident. Even by Wednesday, Josh's physical transformation is remarkable. His lips and cheeks are pink again, and he's much more vibrant and alert. He's still shy while he describes his trip, but, just like Ray, he seems unable to contain his smile.
"It wasn't as intense as I expected it to be," he says. He didn't have many visions but does recall feeling shame and embarrassment.
"I had probably every feeling," he says, and then reconsiders. "I wasn't really scared."
While Josh didn't gain too much insight into his addiction, he repeats that that wasn't his expectation. "I feel almost the same as I did the day before I took [ibogaine]," he says confidently, "but I know I don't have to do methadone anymore."
Perhaps because he's 20 years older, Joe Alex doesn't recover as fast and is still groggy on Wednesday evening. After some ear-acupuncture, Thai massage and a guided meditation exercise, Joe Alex curls up on the carpet and weeps softly, murmuring that it's hard to forgive himself, that he is feeling powerful shame and guilt.
When Gabriel comes to pick them up on Friday, Joe Alex's condition has improved. He and Josh sit side by side on the couch as they wait to depart the clinic, both more mellow and less anxious to depart than Ted and Ray before them. Both men have been through excruciating heroin withdrawals before and seem stunned by their ability to function and feel relatively normal so soon.
By now, Joe Alex is invigorated and chatty. He talks animatedly about all the unfinished business he wants to take care of, like getting his teeth fixed, building another motorcycle and helping his daughter buy a house.
"I'm glad I did this," he says firmly. "It's definitely the best detox I've ever had."
On the way back to San Diego, Gabriel stops at a gas station for a pit stop.
"Hey, Doc!" cries Joe Alex like a proud child as he clambers back into the van, "I can feel I've got a little spring in my step!"
For Lotsof, Glick and Mash, progress and legitimacy lie in ibogaine derivatives.
There's not much money to be made in psychedelic drugs, it turns out, and now that Lotsof's patents on ibogaine have expired, there's not really much incentive to try.
But second-generation drugs have not yet been patented and look like they might be as successful as ibogaine, in terms of stopping cravings and withdrawal. Glick has already developed one such drug, a synthesized version of ibogaine called 18 MC.
Mash is also working in a similar direction.
"All the data we've obtained to date suggests that ibogaine gets converted to an active metabolite and that the active metabolite holds promise as a drug candidate," Mash explains. "The ibogaine causes the visions. The active metabolite is what blocks opiate withdrawals, the cravings and the desire to use the drugs."
Until Glick and Mash secure funding to test these non-hallucinatory derivatives on humans, one question remains: how big a part do the visions play in the overall healing process?
One biologist and former crack addict, who asked that his name not be published, told CityBeat in a phone interview that ibogaine presented him with a clear choice to surrender to death or keep on living.
"It doesn't seem like random images that come up," he explained. "I saw a man with graying hair. He was sitting alone in a motel room, and I suddenly realized it was myself, and I had to make a decision whether I was going to kill myself or decide not to and lead a healthy life. That was an image I tried to get rid of, but it kept popping up, like that was the crucial thing I was supposed to see."
Because of testimonials like these, over the years the media has repeatedly portrayed ibogaine as a possible "magic bullet" cure for addiction. But even the most ardent ibogaine supporters say this is hogwash.
"You have to do a tremendous amount of work," affirms Kroupa, the former heroin addict. "One thing that is absolutely certain is that after ibogaine, you need to have some sort of aftercare plan in place. Whatever that means for you [because] problems will not magically vanish. Ibogaine will not hand you a brand new life."
CityBeat followed five desperate men to the Ibogaine Association in Tijuana to see firsthand how ibogaine really works. Four of them returned visibly healthier, free from cravings and relatively optimistic about their future. But how far away from their former lives did ibogaine really take them?
As of press time, Ted remains unreachable by phone and e-mail.
Ray has been in jail since Dec. 21, his mother told CityBeat.
"It was almost like he was on a mission once he got home to get back in jail," she said. "I know that that's not exactly the case, but that's what it seemed like. He just went berserk. I was actually glad that he wound up in jail; I was expecting a worse phone call, to be honest."
Joe Alex checked into a sober-living home at the beginning of December and stayed there for a few weeks. Once he returned home to San Bernardino, he "had some slips" and says he "hasn't been completely clean." He is now taking methadone and thinking of going back to the Ibogaine Association for a second treatment.
Josh is still clean, goes to Narcotics Anonymous meetings twice a week, and was on his way to a job interview when CityBeat called to follow up.
"If I ever got in that situation again, I wouldn't even think twice about doing [ibogaine] again . I was practically dead before," says Josh. "I hope I don't. I'm still kind of blown away at how well that worked and the opportunity it's given me."

Website: http://www.sdcitybeat.com/

[silkyill]

i have heard that you can take a small amount of hcl ibogaine to get through your withdrawl.the person that needs it is in his 50's and doesn't think he could get through the treatment if he had to take a full dose.he does about a half of gram of heroin a day.any feedback would be most appreciated.

[Alfa]

This part was missing from my post on page 1:

REDUCTION OF THE NEED FOR SLEEP

In all cases, Ibogaine temporally reduces the patient's need for sleep to as few as three or four hours a night. This effect may last a month or more, gradually returning to normal. Two theories have been put forth concerning this effect. One theory suggests the long-lasting bioavailability of Ibogaine or one of its metabolites. This is in keeping with the pharmacokinetic studies conducted at the University of Miami (Mash, 1995). The second theory suggests the cause is the decrease in the psychological requirements for sleep associated with the necessity to dream. Evidence supporting this theory is that Ibogaine promotes an intense emulation of dreaming that lasts for many hours during its acute stage of activity.

The reduction in the need for sleep is viewed by the majority of patients as a discomfort, since they have used drugs and sleep as an escape mechanism. These patients may require some mild form of sedation during the first days after treatment with Ibogaine. Normal precautions should be taken in providing sedatives to persons with a history of chemical dependence. In a minority of cases, patients have used this newly available time to advantage in their busy work schedules.

LONG-TERM EFFECTS

Long-term are those which may be noticed from one to twenty-four months after treatment, and in some cases even longer. I have provided three examples.
Example One

A heroin-dependent couple was treated. The woman of 26 was a relatively new addict of three months while her 27-year-old husband had a history of over ten years of heroin use. At the time of their treatment a protocol of treating one patient at a time was followed. These were early treatments and the medical and medical support staff were familiarizing themselves with what might be expected during such episodes.

Portions of the treatment episodes were observed by Dr. Carlo Contoreggi, Deputy Medical Director of the Addiction Research Center of the National Institute on Drug Abuse in Baltimore and Dr. Lester Grinspoon of the Harvard School of Medicine.

The husband was treated first, and his wife was completely cooperative and helpful during his treatment. The following day, when the wife was administered her dose of Ibogaine, her husband demanded that he be allowed to leave his room and remain in bed with her. He informed the medical and paramedical staff present that unless he got his way he would create a disturbance to interfere with his wife's treatment. Rather than deal with a belligerent and angry patient, we decided it would be less harmful to let him have his way. He continuously disturbed his wife during her treatment. This resulted in a policy of treating couples simultaneously in separate rooms.

He recovered before his wife, as she had been administered Ibogaine twenty-four hours after his treatment. He complained that he was getting bedsore and was no longer able to stay in bed and asked for permission to go for a bicycle ride. Upon his leaving, his wife broke down and cried in the arms of a female paraclinician, stating she did not know if she could remain with her husband, but she was afraid he would die if she left him. This was a concept he continuously stressed to her during their treatment.

After treatment, he followed a pattern of controlling his wife's contacts with other persons including the treatment team, which was denied access to either of them. We later learned that they both returned to heroin use. However, three months later the wife determined that her husband was incapable of loving himself or her and this was not the life she wished. She stopped using heroin, enrolled in nursing school, filed divorce proceedings against her husband, and is now specializing in psychiatric nursing.

While initially she did not recognize that her decision to stop heroin use was due to her Ibogaine treatment, as the months went by she realized that her determination to change her life was catalyzed by her experience with Ibogaine.

Example Two

A cocaine/cocaine-base dependent patient was treated with the Lotsof Procedure and experienced an acute interruption of his drug use. During his Ibogaine treatment he had a strong impression that if he continued drug use God would punish him. He remained drug-free for about thirty days, after which he increased his drug use over the next months and was retreated. The dose he received proved to be inadequate due to his vomiting of the oral dose and to a bowel movement immediately after the rectal administration of Ibogaine, which he requested to remedy the loss of his oral dose. His drug use continued, but far below his original pretreatment levels.

About six months after his retreatment, the first Ibogaine therapy group sponsored by the International Coalition for Addict Self-Help, directed by psychotherapist Barbara Judd, CSW, was established in New York. The patient attended these sessions until fifteen months after his original treatment, when he recognized that he had to move away from his drug-infested neighborhood. Thereupon he moved to Florida. In Florida, he has remained drug-free, even though he had access to cocaine. He is employed in the construction industry by a business with strict non-drug use guidelines that is owned and run by former drug users.

Example Three

One of the most important concepts learned by persons treated with Ibogaine is that addiction can be reversed. Persons dependent on drugs such as opiates or cocaine are not able to recognize that chemical dependence is a reversible phenomenon.

This third example is of the only chemically-dependent person from the 1962-1963 study to receive a series of treatments at therapeutic levels with Ibogaine. The individual remained free of addiction for approximately three and a half years as a result of his series of treatments.

During that period he moved to California, married, and worked in pharmaceutical sales. He later lost his job and, when offered a ride back to New York, accepted it and returned to a life of minor drug dealing and use that resulted in his arrest and imprisonment.

After his release, he worked for a while as a machinist, then slowly fell back into heroin use and addiction in 1969. Luckily, this was a period when methadone programs were expanding, and he was able to enter one of the better programs run by Beth Israel Hospital. At that time, the programs were well-staffed with doctors, nurses and adequate counselors, and the patient reached a point in his life when he recognized that the life of a heroin addict was not what he wanted. It was not just the heroin, but the scene itself, wherein a human life was without value, where sometimes a human being would be murdered for two cents worth of an innocuous powder in a glassine envelope. The patient was ready to quit heroine, but was a slave to the craving to use opiates for the anxiolytic relief they provided.

Over a period of more than two years, the patient stabilized himself on methadone. He tried heroin once, two weeks after starting methadone, was satisfied with the level of blockage that methadone offered, and never used heroin again.

During the next few years the methadone programs changed. Many of the competent counselors were unable to continue in their positions due to the stress and sense of frustration in their work, a condition common in the treatment community. The Federal government placed more and more restrictions on methadone patients' freedom of movement and, though methadone is anticipated to maintain the methadone client for a period of twenty-four hours, in many cases it does not. For this patient withdrawal signs were setting in at eighteen hours and not twenty-four. The patient began a slow detoxification process from 100mg of methadone per day that took approximately eighteen months.

The final stage of detoxification was followed by the patient's entry into University-level training after he obtained a scholarship to a prominent university. At the time of the detoxification, the philosophy among methadone patients was that you could not get off methadone, but having previously had the Ibogaine experience, the patient stated that he knew addiction was reversible, and that knowledge allowed him to successfully leave addiction behind.

[doublezero]

thankyou alfa, good read, very insightful and inspiring... something swim defently consider in the future, to get off H and methadone, defently some bright hope out there

[oggy]

This is amazing, love it. Would it be ok for an ex heroin/methadone user to try the treatment? Swim is 100% clean now for just 2 weeks but feels amazingly alive, he did go through hell for 3 days and had very spiritual experience and would never use man made drugs again or let himself get addicted ever.

Swim wants more tho, he loves this feeling of life and being "alive" but maybe ibogaine would enlighten him even more.

Is Swim just being greedy for love and happiness?

Love n peace.

[0utrider]

you might wanna give a look at this thread and help me make the article better please
http://www.drugs-forum.com/forum/sho...ighlight=iboga

i might copy some of this thread since this thread has tons of information itself in it

[Dickon]

An Introduction to Ibogaine

by Nick Sandberg
ISBN 0-9538348-1-6 www.ibogaine.co.uk
This piece is not subject to copyright and may be reproduced
Written in 2001, and occasionally updated


Chapters
Introduction
Ibogaine
The Problems of Developing Ibogaine
Casual Ibogaine Treatment
Ibogaine Treatment
How Ibogaine Works
The Bwiti
Ibogaine for Self-development
Iboga Visions
Bibliography



Introduction

Ibogaine is a psychoactive indole alkaloid derived from the rootbark of an African plant - Tabernanthe iboga. In recent years it has been increasingly noted for its ability to treat both drug and alcohol addiction. Both scientific studies and widespread anecdotal reports appear to suggest that a single administration of ibogaine has the ability to both remove the symptoms of drug withdrawal and reduce drug-craving for a period of time after administration. In addition, the drug's psychoactive properties (in large doses it can induce a dreamlike state for a period of hours) have been widely credited with helping users understand and reverse their drug-using behaviour.
Studies suggest that ibogaine has considerable potential in the treatment of addiction to heroin, cocaine, crack cocaine, methadone, and alcohol, with some suggestion that it further be useful in treating tobacco dependence. It has also been suggested that the drug may have considerable potential in the field of psychotherapy, particularly as a treatment for the effects of trauma or conditioning.
A single administration of ibogaine typically has three effects useful in the treatment of drug dependence. Firstly, it causes a massive reduction in the symptoms of drug withdrawal, allowing relatively painless detoxification. Secondly, many users report, and scientific studies confirm, a marked lowering in the desire to use drugs is experienced for a period of time after taking ibogaine, typically between one week and several months. Finally, the drug's psychoactive nature is reported to help many users understand and resolve the issues behind their addictive behaviour.
Ibogaine can be easily administered, in capsule form, and has no addictive effects itself. It is essentially a "one-shot" medication and, used in a clinical setting with proper client screening procedures, the drug thus far appears to be safe to use. Whilst it is rare for an individual to stop using drugs permanently from a single dose of ibogaine, as the initial component in an overall rehabilitation programme the drug would appear to offer much potential.
Although approved for clinical trials (trials on humans) for the treatment of addiction in the US in the early 1990s, problems with financial backing have so hindered the development of ibogaine that, as of mid 2001, it remains undeveloped and thus unavailable to the majority of addicts worldwide. There are however a couple of private clinics, located around the Caribbean and in Mexico, that offer ibogaine treatment at prices starting around £4,000, and some lay treatment providers offer lower cost treatment, without medical facilities, in Europe. In addition, ibogaine, either in pure form or as a plant extract, has become available from some lay sources on the internet.
Ibogaine's current legal status in the UK, and much of the rest of the world, is that of an unlicensed, experimental medication, and it not therefore an offence to possess the drug, though to act as a distributor may be breaking the law. Ibogaine is a restricted substance (possession is illegal) in some countries, including the US, Switzerland, Sweden and Belgium.



Ibogaine

Of the various substances that have, at one time or another, been proposed as being useful in the treatment of drug or alcohol dependence, ibogaine would certainly appear to be the one offering the greatest real potential. A slightly psychoactive indole alkaloid derived from an African plant, the drug, in plant form, has been used by indigenous groups for millenia. The Bwiti, a Central African religious group, use the rootbark of the Tabernanthe iboga plant for a variety of social and religious purposes, most notably as the central component of a "rite of passage" initiation ceremony intended to confer the status of adulthood upon new group members. In the West, ibogaine is usually administered in the form of the hydrochloride - a fine off-white powder either lab synthesized or chemically extracted from the rootbark.
When administered to persons seeking to beat addiction to heroin, methadone, cocaine or alcohol, a single dose of ibogaine typically achieves the following. Firstly, the complete removal or severe attenuation of the symptoms of drug withdrawal, allowing painless detoxification (occurs with approx. 90% of subjects). Secondly, the removal of the desire to use drugs for a period of between one week and three months (occurs with approx. 60% of subjects). Finally, the revealing of personal issues underlying drug-using behaviour, leading to long-term drug-abstinence (occurs with approx. 30% of subjects).
Ibogaine is not itself addictive and the drug may be taken a second time to help preserve a drug-free state. It should be noted, however, that relatively few people permanently beat addiction solely through using ibogaine, and the treatment should thus be regarded as simply an initial component in an overall rehabilitation strategy.
The discovery that ibogaine could treat drug addiction is usually credited to Howard S. Lotsof - a New York based former heroin user who first took ibogaine in 1962. Lotsof took ibogaine believing it to be a new recreational drug but, 30 hours later, suddenly realized he wasn't experiencing heroin withdrawal, and had no desire to seek drugs. Subsequent casual experimentation by addict friends revealed that this effect was common to others.
Some 20 years later, Lotsof returned to his discovery and set about trying to bring it to the market. He initially set up a charitable foundation with the aim of promoting and developing ibogaine as an anti-addiction medication but, dismayed by the lack of interest shown, later decided to form a company, NDA International, believing a business concern would more likely attract the necessary financial backing. NDA filed patents for the use of ibogaine in the treatment of addiction and began to carry out treatments to better evaluate the drug's potential.
Because, by this time, ibogaine had been made a Schedule 1 restricted substance in the USA (ibogaine was banned along with LSD and psilocybin in the early seventies) NDA chose to carry out experimental ibogaine treatments in Holland. Jan Bastiaans, a highly-regarded Dutch psychotherapist, partnered him and, over the early years of the nineties, they treated some 30 addict volunteers, the results of which were later medically assessed by Dr Ken Alper in a scientific paper (see How Ibogaine Works for ref).
The nineties, after a promising start, proved to be a tough time for ibogaine. In 1991, the US National Institute for Drug Abuse (NIDA), impressed by case reports and animal studies, began studying ibogaine with a view to evaluating its safety. They constructed protocols for the treatment of addiction. In 1993, the US Food and Drug Administration (FDA), who oversee the development of new drugs, approved clinical trials with ibogaine, to be carried out by Dr Deborah Mash of the University of Miami School of Medicine, on behalf of Howard Lotsof's corporation, NDA International.
It was at this point that things started to go astray. The death of a young female heroin addict during treatment in Holland brought an abrupt end to the Dutch project. A subsequent inquest did not find the project organizers guilty of negligence but the lack of scientific knowledge about the effects of ibogaine hindered the establishing of an actual cause of death. (It was believed that the surreptitious smoking of opiates during treatment may have been responsible).
The approved clinical trials commenced but contractual and funding problems that arose between NDA International and the University of Miami brought the trials to a close before completion, (the drug's safety was not an issue). A lengthy legal battle between the two ensued, and developmental work came to a standstill.
In March 1995, after several years spent progressively becoming more interested in ibogaine, a review committee at NIDA suddenly decided to greatly reduce further activity with the drug, apparently having been influenced by critical opinions from the pharmaceuticals industry. Officially, it was reported that the death in Holland was of concern, and that NIDA were disappointed that ibogaine was only shown to keep people off drugs for a period of months, not forever. Howard Lotsof has subsequently pointed out that the death, whilst tragic, was likely caused by concurrent opiate usage and, with regard to the second point, that any drug that could put, say, cancer or AIDS into complete remission for a period of months would be being developed as a matter of national urgency.
Over the last five years, very little has happened. The escalating legal battle between NDA International and the University of Miami, each suing the other for alleged breaches of contract, appears to have ended with the bankruptcy of the former. Yet, as of mid 2001, the precise outcome is not clearly established.
Meanwhile, widening knowledge of the effects of ibogaine has resulted in casual treatments being provided by various individuals in different countries. Though usually undertaken with good intentions, these treatments have frequently been carried out by people with little medical knowledge, and this may have resulted in further tragic incidents.
A couple of small countries, notably Panama and St Kitts, have made ibogaine treatment legally available at private clinics, but only at prices starting around UK£7,000 per treatment (approx US$10,000. Unlicensed medical clinics in Mexico currently offer the treatment slightly more cheaply). As of mid 2001, ibogaine remains in a legal nowhere-land, desperately needed by millions of addicts worldwide, but, tragically, little closer to becoming easily available.



The Problems of Developing Ibogaine

Ibogaine development has been beset with hold-ups for years. The existing legal disputes may now be close to resolution, but ibogaine still needs the participation of a pharmaceutical company for it to make it to the mass market. The business of developing new medications is solely in the hands of the private sector - the pharmaceutical corporations - and the problems that drugs companies appear to have with ibogaine are many.
Firstly, as a drug derived from a natural source, patent options are more limited than they would be for a drug that can only be created in the lab. Potentially, this greatly reduces the level of financial return that the drug could provide, of serious concern considering the degree of backing needed to bring a new drug to the market. Whilst, in the West, there are governmental provisions in place to encourage companies to develop drugs that could be socially useful, to date no one seems interested in taking advantage of them for ibogaine.
Secondly, ibogaine is not a maintenance drug - it is not taken repeatedly over a short period of time - and is usually administered only once. As a general rule, medications developed by the drugs companies, for whatever purpose, are maintenance drugs, for only maintenance drugs allow sufficient financial return to justify the necessary prior outlay on research and development.
Thirdly, industry insiders relate that there are public relations concerns when developing medications for groups that are negatively socially marginalized in the way drug addicts have become. Drug companies, like most modern corporations, are acutely image-sensitive and there are thus concerns that developing medications for addicts could bring about a deterioration in their overall market value.
Finally, some believe that bringing an addiction medication of ibogaine's potential to the market may present "conflict of interest" problems, of dubious moral worth, to other corporate bodies involved with the sale of licensed recreational substances such as alcohol or tobacco.
The root of the problem that ibogaine faces in becoming available is that our society lacks any mechanism by which a substance of this nature, offering high social benefits but only marginal direct financial return, can be developed. Drugs companies are shareholder based, and so can only develop medications that offer sustained, direct financial return. Whilst ibogaine potentially offers immense savings to government in terms of reduced spending on social welfare and crime prevention, there is no mechanism by which this saving at a public level can be used to induce a corporation to develop the drug.
Assuming the absence of corporate backing, about the most likely route by which ibogaine might become legally available is via projects carried out by local government drug dependency units. Projects of this nature, once started, would allow addicts access to safe, low-cost treatment and, as each project generated more knowledge and data, so drug treatment centres in other areas could make use of the same to develop their own ibogaine protocols. As of mid 2001, however, no projects of this nature are underway, although East European countries appear to be at the forefront of those interested. In addition, the medical laws of some countries allow registered practitioners to prescribe an unlicensed medication like ibogaine, usually providing the subject has given their "fully-informed consent."



Casual Ibogaine Treatment

With ibogaine treatment now more available than ever before, in an ever-widening range of settings, more and more knowledge about the drug is gathering. At the time of writing, March 2007, one thing that is becoming increasingly clear is that there is a reasonable degree of risk associated with taking the drug. At least 12 people are recorded as having died in connection with taking ibogaine or other iboga substances over the last decade or so, and there is reason to believe that the number may be higher, with other deaths having occurred in non-clinical settings and without being recorded.

Here is some safety-related information about the drug:

- There is an inherent level of risk with ibogaine treatment. Twelve people are known to have died in connection with taking ibogaine or other iboga alkaloids. In actuality, the figure is likely higher, given that ibogaine is frequently administered in surroundings where people may be reluctant to contact the authorities in the event of something going wrong. Statistically, a ballpark figure for deaths during treatment is probably of the order of 1 in 300. (This is based on 12 recorded deaths having occurred within 3611 recorded treatments, outside of Africa, as of March 2007). The following factors have been identified as having caused death:

• having a pre-existing heart condition, sometimes one not detectable by EKG
• using opiates when on ibogaine, or shortly afterwards
• using the rootbark or iboga extract. Ibogaine HCl is statistically much safer
• taking ibogaine outside of a clinical facility. Persons taking ibogaine need constant supervision and, ideally, online heart monitoring

- Ibogaine is principally recognised for its ability to vastly reduce the symptoms of drug withdrawal, thus allowing addicts to detox relatively painlessly. Any other claims made for the drug, such as that it creates long-term drug-abstinence, or removes the effects of trauma or conditioning in either addicts or non-addicts, may have a degree of truth but are a great deal less substantiated.
- You must be medically tested before you take ibogaine. Proper clinical testing of heart and liver function are the absolute minimum. The site author is not aware of any reputable treatment provider who would allow you to take ibogaine without prior medical testing. Do not go with someone who does not insist on it. Ideally, you should have constant monitoring of heart function whilst on the drug, and medically-trained staff present.
- Beware of listening excessively to the advice of just one individual when deciding whether or not to take ibogaine. Ibogaine's effects can be life-changing, and it is common for someone who has had a very positive experience to do their utmost to "spread the message," possibly allowing their enthusiasm to override the very real concerns about safety.
- If you are thinking of taking ibogaine for personal development and haven't yet been involved in proper therapy (therapy where there's an open admission by the individual of the presence of emotional issues), be aware that you may be being attracted to a "quick fix" strategy that avoids really dealing with deeper issues. If this is the case, ibogaine could possibly make things worse. For some, using psychoactive substances can invoke disturbing reactions as the mind's defences struggle to keep down rising repressed material. Drugs like ibogaine, ketamine, LSD and MDMA (Ecstasy), have been used in the past by therapists, but only as one component of an overall therapeutic strategy. Using the drug out of this context could cause more harm than good.




Ibogaine Treatment

(This article has been reproduced for interest value only).
Ibogaine, an indole alkaloid derived from an African plant source, has for many years been recognized for its ability to interrupt drug dependency. Specifically, it can be effective in the treatment of withdrawal from heroin, methadone, cocaine (inc. crack cocaine), amphetamine, and alcohol.
Although it is slightly psychoactive, ibogaine should not be confused with drugs like LSD or psilocybin. Ibogaine's effects are far longer lasting and can be intensely physical in some users. The drug should be treated with respect and not administered by persons unfamiliar with basic medical procedures. Because vomiting can be a problem with ibogaine treatment, persons administering should ensure especially that they are fully familiar with resuscitation procedures and have rapid access to the emergency services should they be required. It is important persons interested in receiving ibogaine treatment are properly screened. Failure to do so may have resulted in previous tragic accidents. Heart (EKG) and liver (Blood) screening are the absolute minimum.


PREPARATION OF THE CLIENT - The prospective client should attend several informal interviews to ensure he or she is fully aware of the following information relating to ibogaine treatment:
(i) - that ibogaine is principally a detox tool and that, whilst it can help with drug-craving for brief periods as well as help a person understand why they started using drugs, it will still be up to them to stay off. As a general rule, addicts who regard ibogaine as simply something which is supposed to "cure them" rarely have success.
(ii) - that ibogaine is an experimental medication, not recognized as a licensed medicine anywhere in the Western world, and that other options for treating their addiction exist.
(iii) - that deaths have occurred in association with ibogaine treatment, and that it must therefore be regarded as having a definite level of risk, though proper client screening procedures should be able to keep this to a minimum. Specifically, anyone with any history of heart problems should be very wary of taking ibogaine. In recent years there have been several reports of mysterious deaths associated with cardiac problems.
A basic level of physical and psychological screening is essential prior to a person being considered suitable for ibogaine treatment. A blood test should be undertaken to check for liver abnormalities and to ensure general health is good. An EKG should be undertaken to check heart function. Problems with the liver, heart or lungs should result in exclusion from treatment unless subsequent professional medical opinion advises to the contrary. Many long-term addicts may have developed medical health problems which would make ibogaine treatment in a non-clinical setting dangerous. These tests can be often be organized by drug dependency units or private doctors.
Attention should also be paid to the clients' mental state. Persons exhibiting signs of significant mental disorder should be excluded from treatment.

DOSAGE - Assuming the client is sufficiently well to be treated, their bodyweight in kilos should be measured, and a suitable dose of ibogaine calculated.
Pure ibogaine HCl is typically administered at doses of around 10 milligrams per kilo bodyweight (mg/k) for men, and 9 mg/k for women. To calculate the dose, multiply the client's bodyweight in kilos by either 10 (for men) or 9 (for women) and you will have the dose in milligrams.
Example: An 8 stone female alcoholic will require about 460mgs of ibogaine HCl, a little under half a gram. (8 stone x 14 = 112 lbs. 112 / 2.2 = 50.9 kgs. 50.9 x 9 = 458mgs)
Note that this is for pure ibogaine HCl, one of two forms of the drug commonly available in Europe. The other is the "Indra iboga extract," which is believed to be approximately one quarter the strength of pure HCl, meaning clients will require roughly four times the amount. Although the "Indra" product is becoming increasingly available in Europe, it is known to induce more vomiting than the HCl. In January 2000, a 40 year old heroin addict died in London after vomit clogged his airways some 40 hours after taking a dose of this extract.
For opiate addicts, such as those using heroin or methadone, the dose of ibogaine HCl is typically doubled, to around 20mg/k for men, and 18mg/k for women. This is because the opiates in a person's system partially block ibogaine's effect.
It is recommended that ibogaine only be given as a single dose, in the range of 9-10 mg/k. From what is known, this appears to be the safest way to take the drug, bearing in mind that higher doses can always be taken in subsequent sessions if necessary. When re-dosing, it is recommended to wait at least one month as ibogaine and its metabolites linger in the body.

TREATMENT PREPARATION - It is very important that the client's drug intake be regulated for 24 hours prior to taking the main dose of ibogaine. This will prevent the ibogaine from reacting with any other drugs still in the body, which research indicates may lead to adverse reactions. This means that no heroin, no cocaine and no other drugs should be taken for a minimum of 12 hours prior to taking the main dose of ibogaine. No methadone for a minimum of 24 hours. Drug use for the days prior to treatment should therefore be planned in advance to ensure this is possible. In addition, no stimulants should be taken for at least 24 hours prior to taking the main dose of ibogaine. Normal doses of benzodiazepines like valium can safely be taken prior to ibogaine to assist in reducing anxiety or to help the client sleep if necessary.
Ibogaine is recognized as having the ability to potentiate other drug reactions, meaning it is very important persons under its influence do not get access to drugs. Any level of opiate or cocaine usage whilst on ibogaine could be very dangerous.
24 hours prior to taking the main dose of ibogaine, a test dose of about 100mg of the drug should be taken. Allergic reactions have not been reported to the best of the writer's knowledge but, in the event of one occurring, the treatment should not proceed. Some minor level of ataxia, (difficulty in standing upright), nausea, and aural amplification may be experienced at this dose level. This is quite normal.
Food consumption should cease about 12 hours prior to the main dose of ibogaine being taken. To make this easy to bear, many people take ibogaine first thing in the morning, as a replacement for their morning fix. 1 hour prior to taking the main dose, an anti-nauseant such as domperidone (or similar travel sickness medication) may be taken to try and reduce nausea.
The treatment setting is important in that the client should feel relaxed and relatively easy in themselves. This will help to limit anxiety. Noise should be low throughout (ibogaine causes sounds to be heard much louder than usual), and the light level adjustable. Remember that ibogaine incapacitates some people for several days, so make sure that peaceful, dimly lit conditions can be maintained.
A "sitter" should be present with the client for the duration of the experience, which usually lasts between 20 and 30 hours, but in some cases has been known to go on for 3 days. This should ideally be someone experienced in ibogaine administration, or otherwise a close friend. It is unlikely much communication will be attempted in this time and the client should therefore be attended in peace. Requests for water may be fulfilled but nothing else should be taken.

THE EXPERIENCE - The client will likely experience the drug taking effect after between 30 minutes and 2 hours. Withdrawal symptoms should be eliminated or easily manageable. There will likely be ataxia (problems getting upright) accompanied by a buzzing noise in the ears. Sounds will become louder, bright light hard to bear. Some people report feeling nauseous and there may be a sensation of pulsing in the body, rather as though it were being "cranked up to a new frequency." These sensations are quite normal.
Vomiting within 3 hours of taking the main dose may result in some of the ibogaine leaving the body before it can be absorbed. In such circumstances, giving more may be considered or perhaps the treatment aborted. Examining the vomit may reveal if the drug has left the body. Be aware of the dangers of both overdosing and using stepped doses if considering giving more ibogaine to make up for that lost in vomit, especially if this is the first time someone has used the drug.
The experience of taking ibogaine varies so much from person to person, it is difficult to prejudge just what will happen for any one individual. However, there are generally two, distinct phases to the experience.
First, the "oneirophrenic" or "dream-creating" phase. This generally lasts several hours and usually consists of the user experiencing dream-like visions with eyelids closed, which disappear once the eyes are open. The visions may appear to be actual memories running, rather as though a film of one's life was being shown inside the head, or may take the form of characters acting out roles, rather as though a play was taking place inside the head. However, many people report no visual sensations and this is not a problem. People may experience feelings and sensations associated with childhood and early life.
Secondly, the "processing" phase, which follows once the first stage is concluded. This phase is characterized by high levels of mental activity - interiorized processing that allows the material revealed in the first phase to be assimilated and interpreted. People frequently experience comprehending for the first time the reasons why they became involved with drugs. Though ibogaine affects different people in different ways, the oneirophrenic phase typically starts 1-2 hours after taking the main dose, and the processing phase about 3-6 hours later, usually lasting for between 8 and 14 hours. People sometimes experience very negative feelings on ibogaine. If this appears to be happening, the person attending could try to give them reassurance that things are OK. Whatever arises will pass.
What is described above is a typical session but it is by no means unknown for people to be up and moving around within a few hours of taking the main dose, apparently having experienced very little. Alternately, some remain in bed for half a week. In addition, opiate addicts frequently experience little or nothing of the "oneirophrenic" phase. Sessions that are over quickly are usually less effective, and ibogaine does appear to have very little effect on some individuals, regardless of dose level.
Potential treatment providers please note: It is important to realize just how variable the drug's effects can be on different people. Tragic incidents can occur if safety procedures become lax after a string of successful treatments. Because, when ibogaine works, its effect can seem quite miraculous, it is very easy for people who are not medically experienced to start to relax pre-treatment screening procedures in their keenness to treat people and this is dangerous.

POST IBOGAINE - If the treatment has been successful, the client should be clean having experienced little or no withdrawal. In addition, many experience no desire to use drugs for a period of weeks afterward. Furthermore, some users report gaining insights into their drug-using behaviour. As a general rule, ibogaine is most effective for older addicts, a casual study indicating that those over 35 have a far better chance of staying clean than those in their twenties.
In cases where the treatment has been successful, but the client begins to experience the desire to use drugs again after some weeks, repeat dosing with ibogaine can be undertaken. Remember that persons not currently using opiates require ibogaine at a maximum dose of around 10mg/k. Re-dosing with ibogaine at less than one month intervals may be risky, as metabolites of the drug can remain in the body for this length of time.
Melatonin and B vitamins have been suggested as useful after using ibogaine. Some believe they help sustain the drug's effect.

POST IBOGAINE REHAB AND THERAPY - A single dose or multiple doses, given over a period, of ibogaine will occasionally be enough to keep someone off drugs permanently. But for most the truth is that, unless suitable post-ibogaine work is undertaken, a fairly rapid relapse to old ways is likely.
It is simply not possible to give guidelines that will be valid for everyone, for we are all different. However, for many, the addict should ideally enter rehabilitation as soon as possible after the treatment. In the writer's opinion, the best rehab program, and likely the one most suitable for those who have just taken ibogaine, is the Residential Addiction Foundation (RAF) program run by the Humaniversity in Egmont-aan-Zee, Holland, see www.humaniversity.nl for further details.
Other alternatives include any long-term (six months and up) residential rehab program available locally. Where residential rehab is not desirous, or not an option, suitable therapy should be seriously considered. Observations of the ethnic, religious use of the drug and first and second hand experience indicate to the writer that the most suitable types of therapy will be body-based and work around catharsis, confrontation and emotional release. "Talking only" type therapy, such as counselling may be effective in some cases but usually less so. Encounter therapy is often highly suitable for recovering addicts, as is primal therapy, bioenergetics, and indeed anything that sets out to assist the individual contact and release repressed emotions, frequently the root cause of addiction. More gentle, integrative work may also be useful. Dance structures such as 5 Rhythms or Biodanza may be helpful, either as a back-up to deeper work or on their own.
Attention should also be given to pleasure. Long term drug use will have likely had the effect of causing the addict's dopamine system to have been "hard-wired" to associate pleasure with drug use. This is the reason why many who have beaten addiction in the short term frequently relapse. A brief period of exposure to drug-using stimuli, especially at a time when a former addict feels vulnerable, often results in a return to addiction. Everyone needs pleasure and so the recovering addict must take steps to ensure they can get enjoyment out of life without using drugs. For the majority this will mean work on their sex lives. Sexual stimulation, and particularly orgasm, is the principle means by which the healthy body gains pleasure and releases tension. Work to increase the former user's ability to be intimate, both socially and sexually, is very important. Tantra workshops, touch therapy, or other intimacy-focussed processes are an excellent idea.

POST IBOGAINE PROBLEMS - Feelings of deep contentment - although less common with long term heroin users, many people using ibogaine feel in very high spirits for a period of days or sometimes weeks after taking ibogaine. Clients report feeling that their life is now totally straightened out, they don't need to do rehab, and everything is going to be just wonderful. Unfortunately, this feeling usually passes after a week or so. It is important to remember this as some people feel so good for a week or so after using ibogaine, they barely notice when they start to get the urge to use drugs again and so quickly relapse.
Learned behaviour or conditioning - ibogaine is widely noted as having the ability to "reset" a persons learned behaviour patterns, leaving them free from compulsive urges, drug-related or otherwise. Again, this usually only lasts for a period of days or weeks, and so attention should be paid to any drug-using stimuli in one's environment after this time.
Feelings of anxiety or paranoia - for some users the experience can prove quite harrowing. The drug can have the effect of radically altering the way a person looks at themselves and the world around them. Deep-rooted feelings of insecurity that may have been present since childhood can be uprooted and, when this happens, it can leave a person feeling disorientated and anxious for some time afterward. This will clear and is actually an indication that the drug has worked well.
Sleeplessness - many people find they require less sleep for a period of time post-ibogaine. This is quite normal.

RETURNING TO DRUG USE - If a return to drug use is anticipated post-ibogaine, it is imperative the client does not restart at the dosage level they were using prior to treatment. Ibogaine "resets" many brain functions relating to drug usage and to return to heavy usage could easily result in overdosing, and possibly death.



How Ibogaine Works

Just how ibogaine works is a long way from being completely understood. However, enough work has been done for it to be possible to present some insights from the fields of neurology and psychology.
Neurology - Animal studies have revealed ibogaine to be active at many receptor sites associated with drug dependence and its treatment. These include the kappa and mu opiate receptors, serotonin receptors, dopamine receptors, sigma receptors and the NMDA ion channel. Being active at so many sites, ibogaine does not lend itself to easy scientific evaluation, and it is thus likely to be years before scientists develop a good understanding of just how the drug works. However, basic conclusions have been reached by some scientists, and interesting new lines of research uncovered by others.
Through analysing the urine of people undergoing ibogaine treatment in Holland and St Kitts, Dr Deborah Mash believes she has identified the powerful role played by the metabolite, noribogaine. Noribogaine remains in the body for much longer than ibogaine itself and has a higher affinity for many of the receptor sites mentioned above, including the opiate receptors. It may be that an individual's ability to metabolize this substance from ibogaine, which takes place via enzyme activity in the liver, is important in determining just how successful treatment will be long-term.
In addition, scientists at the US National Institute of Drug Abuse (NIDA) have also studied the way that drugs, like ibogaine, which are active at the n-Methyl-d-Aspartate (NMDA) receptor apparently have addiction-interrupting effects. Other psychoactives are also known to be active at this site. Ibogaine's effect on the dopaminergic system, known to be influential in addiction, has also been studied in animals. Some have commented that the drug appears to have a kind of "reset button" effect, temporarily overwhelming craving and learned behaviour patterns.
In total, around 170 studies of the effects of ibogaine on animals have now been published. The conclusions of these papers are well summarized in Chapter 3 of the of the 1999 edition of The Alkaloids - Pharmacology of Ibogaine and Ibogaine-related Alkaloids, Piotr Popik and Phil Skolnick, (1999).
In addition, four clinical studies of the effects of ibogaine have been published. They are:
Luciano, DJ. (1998). Observations on treatment with Ibogaine. (American Journal of Addictions 7, 89-90).
Alper, KR, Lotsof, HS, Frencken, GMN, Luciano, DJ, and Bastiaans, J (1999). Treatment of Acute Opioid Withdrawal Syndrome with Ibogaine. (American Journal of Addictions 8, 234-242).
Luciano DJ, Della Sera, EA, and Jethmal, EG (2000). Neurologic, electroencephalographic and general medical observations in subjects administered ibogaine. (Bulletin of Multidisciplinary Association for Psychedelic Studies 9, 27-30).
Mash DC, Kovera CA, Pablo J, Tyndale RF, Ervin FD, Williams IC, Singleton EG, Mayor M (2000). Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures. (Ann N Y Acad Sci 2000; 914:394-401).
In the last paper, online at www.ibogaine.co.uk/mash.htm, Dr Deborah Mash presents data demonstrating ibogaine's effectiveness in the treatment of opiate and cocaine withdrawal and subsequent drug craving in a case study of 27 patients. As of early 2001, she has treated over 100 people with ibogaine at the Healing Visions clinic in St Kitts.
In attempting to sum up the scientific research that has thus far been done, it might be said that the role of the metabolite noribogaine is likely important in achieving elimination of drug withdrawal syndrome, that activity at the NMDA receptor may be significant in understanding ibogaine's psychoactive effects, and that the drug's effect on the dopaminergic system is likely very influential with regard to the reduction of drug craving and alterations in learned behaviour.

Psychological - Psychologists attached to drug-dependency units have frequently noted that substance abusers very often show signs of having suffered considerable childhood trauma or conditioning. Research in this field has well summarized by Jane Wilson of the University of Stirling in her paper Childhood Trauma, Adult Psychopathology and Addiction.
Trauma is usually a single negative event, the memory of which and associated feelings are repressed. Conditioning is the process by which parents seek to alter their child's behaviour by repeatedly punishing certain acts, usually to try and ensure the child's successful integration into society.
One problem in treating the effects of both trauma and conditioning is that, because the original traumatic event or act of conditioning is repressed, the individual has no conscious memory of it having taken place and a person's defences may make any entry into this area difficult. Ibogaine treatment has frequently been reported to assist in the recall of repressed memories and further aid their processing, thus potentially giving the drug a major role in psychotherapy. However, whilst the cognitive retrieval of repressed material may take place, in the writer's experience most users do not experience a significant degree of emotional connection to the repressed event or events either at the time of ibogaine ingestion or later. It is therefore recommended that ibogaine not be administered in isolation, but rather as simply one stage of an wider therapeutic strategy.
In addition, it is recognized that, regardless of the degree to which the processing of repressed material has taken place, ibogaine does open up virtually all users to open and frank discussion of personal problems for a period of at least a week or so after use, an effect which may be put to good use in therapy.
Psychologically, the drug is essentially "oneirogenic" in that it induces dream behaviour with the ego perspective relatively intact. Modern theories of dreaming often relate that dreams appear to be pseudo-sensory experiences that serve to diffuse the stresses resulting from unresolved emotional conflicts of the day before. In a similar way, it seems to be that ibogaine induces dreams that serve to try and reduces stresses whose origin is much earlier. Ibogaine visions frequently lend themselves well to the principles of dream analysis derived from Jung and others.



The Bwiti

The Bwiti are a Central African religious group whose usage of Tabernanthe iboga, the plant source of ibogaine, forms an integral part of their culture. The rootbark of the plant is known colloquially as "iboga" or "eboka." It contains approximately 12 different alkaloids, of which ibogaine is merely one. Others, such as tabernanthine or ibogamine, are also likely psychoactive.
The word "Bwiti" refers both to the religion - the Bwiti religion, and the group that practice it - The Bwiti. There are estimated to be approximately 2-3 million Bwiti members scattered in groups throughout the countries of Gabon, Zaire, and the Cameroun. Most are from the two principal tribal groups of the area, the Fang and the Mitsogho. Fang Bwiti and Mitsogho Bwiti may be distinguished by their ritual practices and beliefs. It is generally believed that iboga use only spread to these local tribespeople over the last few centuries, having originated with pygmy groups in the jungles of the Congo basin many thousands of years earlier. This migration is understood by the plant's indigenous users as resembling its function, Bwiti myths frequently using images of the lightly wooded grasslands and the dense Congo jungle as symbols of the conscious and the unconscious mind.
Iboga is used for an assortment of purposes within the group, notably as an aid to concentration and to stimulate recovery from illness. Its principal sacramental use is as the central component in the so-called "Bwiti initiation ritual" - an intricate 3-day "rebirth" ceremony, the completion of which is a necessity if one is to become a member of the group. Both sexes are initiated, typically between the eighth and thirteenth birthday, and the ceremony usually begins on the Thursday, ending Sunday morning.
Prior to the ritual's commencement, certain preparatory exercises are undertaken for the purpose of reinforcing the experience. These include the writing and symbolic burning of a "confession" - a written record of all one's moral transgressions, and the undertaking of various rituals, notably one in which the initiate crawls through the legs of local women whilst immersed in a nearby stream, an exercise intended to symbolically reproduce the journey of the sperm to fertilization.
During the ritual itself, iboga is eaten on the first night and may be further consumed on subsequent nights should it be deemed necessary. The initiate's consumption of iboga is supervised by the "nganga," a priest of the Bwiti religion who, being knowledgeable of the effects of iboga, can tell when the initiate has had sufficient.
The overall aim of the ritual is to cause the initiate to be both emotionally and spiritually "reborn," such that they may take their place within the group as a true adult. The consumption of a high dose of iboga is intended to help achieve this by bringing about a deep, dreamlike descent into the world of the unconscious with the effect of both bringing into awareness repressed material and causing a reconnection to the world of the ancestors. If the initiation proceeds well, it is believed that the initiate will actually "meet the Bwiti," envisioned as the primordial male and female originators of the religion, residing in the depths of the unconscious.
The Bwiti initiation ritual, as this "rebirth" ceremony has come to be known, has in recent years attracted the attention of some Westerners who find themselves romantically drawn to the notion of travelling to the region and undertaking it themselves. Anyone considering doing this should be aware of three things. Firstly, that both the Cameroun and Zaire, two of the three countries where the Bwiti are located, are now regarded as being acutely dangerous for Westerners (Zaire especially). Secondly, that, in Gabon, the remaining country, only the least reputable groups would usually consider initiating Westerners, and then almost certainly only undertake the task for financial gain, likely in a half-hearted fashion. Finally, it should be remembered that each year some local initiates are believed to die during the ceremony, bizarre court cases between parents and priests frequently resulting.



Ibogaine for Self-development

The use of ibogaine is not restricted to those seeking to beat drug or alcohol dependence. Individuals seeking personal development, access to more "spiritual" sides of their nature, or a breakthrough in overcoming a psychological block may also find the drug useful.
What is especially interesting about ibogaine is that it allows the user access to the unconscious with the ego perspective relatively intact, that's to say, in relatively normal consciousness. In addition, the intensity of the experience can usually be regulated to some degree, the dreamlike visions normally ceasing once the eyes are opened. Another interesting aspect is that, despite its origins, the visions that occur with ibogaine do not appear to feature the "plant teacher" figures common to the visionary experiences associated with entheogens like ayahuasca or peyote, but rather appear to consist of a more direct encounter with one's self.
These benefits have resulted in ibogaine being used as an adjunct to therapy by a handful of psychotherapists over the years, most notably Chilean psychiatrist Claudio Naranjo, who details some sessions in his book, The Healing Journey. The objective of an ibogaine session is invariably to allow the individual to become aware of unconscious processes that may be blocking their personal development. Ibogaine appears particularly suitable for this task with users frequently reporting that the drug gave them a "hotline to their own personal guru."
Whilst ibogaine may seem like an ideal "personalized high-speed psychotherapy" to some, there are however problems with using ibogaine for personal development work, especially outside of the professional psychotherapeutic context. The dose for therapeutic use is usually around 5-8mgs per kilo bodyweight, and whilst this is undoubtedly a far safer amount than the 20mg/k dose sometimes used to treat opiate addiction, the experience can still prove both physically and emotionally gruelling for some. It is important that the individual's physical and psychological integrity is reliably assessed prior to taking the drug, or, when ibogaine is being considered as a "last ditch" strategy, a risk-benefit assessment made with regard to any potential gain or loss that may occur.
For those thinking of taking ibogaine for personal development who haven't yet been involved in therapy, it is important to be aware that using the drug may appear attractive simply because it represents a treatment that avoids the formal psychotherapeutic process. If this is the case, there is a possibility that ibogaine could make problems worse. When a lot of repressed material is present, and for many brought up in the West this will inevitably be the case, psychoactive drug usage can sometimes invoke dangerous reactions as defence mechanisms struggle to keep down rising painful material. This can result in delusional or neurotic beliefs that persist long after the session is over.
It is also important to realize that using ibogaine alone will unlikely be sufficient to bring about deep personal transformation. The drug typically gives people mental insights into repressed aspects of their psyche, but without significant emotional connection. Other therapeutic work, ideally something with a strong cathartic element, is highly recommended to allow the experience to be properly processed.



Iboga Visions

Interpreting the dreamlike visions of the ibogaine experience can prove a fascinating yet difficult task. The "oneirophrenic" phase of the session frequently throws up much material from the unconscious, and whilst the later, "processing" phase of the session, characterized by many hours of frenzied mental activity, may shed light on the meaning of what has been seen for some, as often as not the individual emerges from the session little wiser as to the significance of what they have experienced.
Because ibogaine visions frequently reveal the presence and nature of deeply sensitive issues, cloaked in symbolism, their subsequent misinterpretation is understandably common. This section will therefore cover some basic aspects of the iboga visionary experience such that individuals using the drug might better benefit from the experience.
It is worth remembering that, no matter what they may appear to be about, ibogaine visions invariably contain much personal content. One symbolic device that often appears to be used by the drug is the cloaking of personal issues as world affairs, frequently either political or ecological scenarios that appear to threaten the planet.
One example of this is that of the opiate user who experienced being shown that mankind was an evolutionary mistake that was now destroying the world - the revealing of deep-rooted feelings of lack of self-worth. Another example is the individual, whose father had exerted a excessively controlling influence over his childhood, who experienced being shown that the world was under the control of elite banking groups. Whilst the scenario experienced may appear valid to the individual, and may indeed even be valid, it should be remembered that there will invariably be much personal significance.
Psychologically, the action of ibogaine is always to attempt to bring repressed material to light - to make conscious what is unconscious. This it does at a rate frequently too fast for an individual to fully process and integrate during the session itself. Experience also indicates that for many this release appears to continue long after the drug has left the system. Consequently, even when little has been experienced visually, it is common for the individual to emerge from the session with their defences overwhelmed by rising unconscious material. It is for this reason that I recommend that the drug only be used by those regularly involved in therapy, and particularly therapeutic structures revolving around the cathartic release of emotions and their bodily integration - Bioenergetics, Primal Therapy, Dynamic Meditation, Lowen Technique, Humaniversity Therapy, or similar. Where this is not undertaken, the inexperienced user may find themselves drawn to bizarre belief patterns or perhaps excessively concerned with issues of "control" for a period of time, perhaps even years, after taking ibogaine. Issues relating to mother or father may be projected onto younger women or older men and there may be a tendency to retreat "into the head," to avoid confrontation with issues of sexuality and personal power. All such patterns should pass with time, and the process of integration may be considerably speeded up by undertaking suitable therapy.



Bibliography

Ali, S.F. (editor) (2000). The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines, New York Academy of Sciences.
Alper, K.R & Glick, S.D. (editors) (2001). Ibogaine: Proceedings of the First International Conference, Academic Press, San Diego, California.
Beal, D & DeRienzo, P. (1997). The Ibogaine Story, Autonomedia 1997.
Bureau, R. (date unknown). Péril Blanc, publisher unknown.
Fernandez J.W. (1982). Bwiti: An Ethnography of the Religious Imagination in Africa, Princeton, Princeton University Press.
Fernandez J.W. (1972). Tabernanthe iboga: Narcotic Ecstasis and the Work of the Ancestors, in: P.T. Furst (Ed.), Flesh of the Gods. The Ritual Use of Hallucinogens, Praeger, New York & Washington.
Mary A., (1983). La naissance à l’envers. Essai sur le rituel du Bwiti Fang au Gabon, Paris, L’Harmattan.
Naranjo, C. (1973) The Healing Journey, Ballantine.
Popik, P & Skolnick, P. (1999). Pharmacology of Ibogaine and Ibogaine-related Alkaloids in: The Alkaloids, Academic Press.

Reputation Comments on this post:

giving you lots of rep for this wonderful ibogaine introduction...i hope it turns into a wiki

[0utrider]

first of i wanna share this with you:

Here you can find a collection of Iboga/Ibogaine documentaries. Quite interesting. It is a torrent file so you need BitTorrent to download it, which is easily found and not hard to install/configure.

The Download Link:IBOGA ebook and video collection about ibogaine
(http://thepiratebay.org/torrent/5036448/IBOGA_ebook_and_video_collection_about_ibogaine)
that's whats in it:

A collection of Videos and scientific articles about the Iboga, Ibogaine and its anti-addictive, healing properties.
Iboga/Ibogaine Scientific Articles & eBooks:

* eBook: Ibogaine - Proceedings from the First International Conference
* 200 PDFs, DOCs and PPTs, scientific literature, studies, ebooks, regimen and therapy descriptions, summaries, etc.

Ibogaine/Iboga Video Collection:

A video collection about the ANTIADDICTIVE medication: ibogaine, that can interrupt a 20 years long heroin addiction and raise the levels of neurotropic substances in the brain that is lowered by the narcotics to help the recovery. But more research i needed to be done, to ensure safe treatments and help against one of the most devastating sicknesses in the modern world: The addiction diseases.

*Facing the Habit 134 592 kb
*Ibogaine Reports - Beyond 2000. 92 915kb
*One Life Detox Or Die Ibogaine(BSLMasked) 107 800 kb
*Ibogaine - Rite of Passage 543 501 kb
*Tribe Babongo Iboga Initiation
*L'IBOGA Les Hommes du Bois Sacre (in French)
*Antropologia - Las puertas de la percepcion (in Spanish)

BitTorrent program:Azureus, now called Vuze : Bittorrent Client (others are also available, for every system and taste)
- if you do download it, please keep it seeding a bite (uploading to others who want it) or at best "forever", as this benefits everyone who is interested in this magic and very uncommon medicine.

If one has specific questions about Ibogaine/Iboga feel free to PM me. I'll answer if the answers can't be found out be reading this thread or using the search engine. Especially general advise is sth i think i can provide as well as place to go to / email / etc. where information about Iboga treatment can be found.

[~lostgurl~]

Please add the video and word doc to the archive. Quick Links > Add Video/Add File