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  #1  
Old 15-02-2008, 08:51
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Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE cop

OK, so SWIM got a bottle of Cheratussin AC
Ingrediants:
100 mg guaifenesin and 10 mg codeine phosphate per 5 mL
3.5% alcohol
118 mL of solution total

What SWIM wants to do is seperate the codeine and the guaifenesin for obvious reasons.

SWIM somehow remembers a DARE officer talking about just how to do this in DARE class ages ago.

The officer said that people would tie the bottle to an end of a rope, and spin it around for a centrifuge like effect. to seperate the two guaifenesin and codeine into two separate layers.

Now, he didn't mention any specifics of course. However, I wonder how long it would take of the swinging for the two ingredients of interest to seperate into pure guaif and codeine.

SWIM would also need to know how to then extract just the codeine from that seperated concoction. Maybe a pipette? Also it would be necessary to know if the codeine would be on top or underneath.

Sounds very possible to me.

Any thoughts? Suggestions? Any one do this before?

Thanks DARE!
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Old 15-04-2008, 15:09
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AW: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

no, but would be interested in more information about this, swim highly doubts it work by just spining around without lab-equip. but maybe there are other possibilities to filter it out?
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Old 05-05-2008, 22:39
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Re: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

SWIM's monkey was just prescribed a bottle of the exact same formula, in the same amount. He is interested in this, if any swimmers could post up info he'd be grateful.
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Old 11-10-2008, 02:34
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Re: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

SWiM just obtained a bottle of the same. Unfortunately DARE doesn't exactly have the most amazing track record for reporting factual information...

If it did work, common sense and a glance at the respective molecular structures would seem to suggest that the codeine would end up on the bottom, but I'm far from sure if this would work at all. I might just tell SWiM to give it a try. All in the name of science, of course.
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Old 11-10-2008, 02:48
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Re: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

Sounds like it's a good idea. That stuff is terrible otherwise.
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Old 11-10-2008, 03:20
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Re: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

About two minutes of digging through the Merck manual suggests the centrifuge method won't work, but SWiM'll probably still give it a try. But considering that he has practically no opiate tolerance whatsoever (w00t! he hasn't touched one for more than a month, and even then he had no more than a mild-to-moderate tolerance), and that I've found sources (here, here and here) suggesting that guaifenesin is by itself pretty nontoxic (I've seen 2.4, 1.2 and 3.6 grams all listed as safe, and sometimes even higher doses are prescribed off-label for treatment of fibromyalgia), and that the solution in SWiM's posession is (100/10 g/c)/5ml, and that SWiM actually has a pretty nasty cough, I suspect he may just give dosing 300/30 a shot and upping slowly as 'necessary'. Just plain tussin (sans robo) suggests 2-400 mg/4 hrs., and the codeine should (?) counteract some of the side effects of the guai., so I figure SWiM should be fine.

Last edited by Felix Guattari; 11-10-2008 at 03:29.
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Old 11-10-2008, 07:16
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Re: Cheratussin AC - seperating the Codeine from the guaifenesin - tip from a DARE co

Look and see what solvents that codeine is soluble in but guaifenesin is not, or vice versa. Filter and throw away the appropriate part. Should not be too complicated to find a solvent that would work. Wikipedia, an MSDS on both drugs, and google should help tons here. Let us know!
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