what is a good starting dose for injecting morphine?

[ihavequestions]

SWIMs friend stole a morphine vial from a hospital recently along with some insulin needles.

SWIM is definetly interested in trying morphine considering heroin is unreliable when it comes to potency, and hydromorphone would be too intense.

anyways, SWIM is SOMEWHAT of a lightweight when it comes to drugs, and would like to know what a good amount in ML of morphine would be for a first timer with a needle. an experienced person will inject SWIM.

something where swim is still coherent thought wise, but enough to give a mild rush and body high.

about how many ML?

[fnord]

5mg is good to start with,carefull morphine is easy to od on.

[samuraigecko]

One agrees, 5mg is a good start and is what is usually given to patients as a first dosage in most hospital situations. Recreational dosages for someone whom is a little more opiate tolerant may be closer to the 10mg to 15mg mark and even higher in some cases but in SWIYour case one would think that IF SWIyou were going to try it at all . . .

(if SWIyou have never injected before then one recommends against it, as soon as SWIyou cross that proverbial line . . . well . . . )

. . . then 5mg is the place to start at, one also agrees with the above, Morphine is less forgiving than some of the other designer opiates and can in some cases be easier to OD on.

Hope this has been of help

[JaWill88]

swim agrees 5 mg but maybe 10mg. but swim will warn the morphine rush isn't very pleasant. gives a shitty pins and needles feeling that is uncomforable. diacetylmorphine on the other hand is very pleasant but that's not a great thing to start. swim suggests doing the morphine any other way but iv as it isn't a good rush.

[rocksmokinmachine]

Originally Posted by JaWill88

swim agrees 5 mg but maybe 10mg. but swim will warn the morphine rush isn't very pleasant. gives a shitty pins and needles feeling that is uncomforable. diacetylmorphine on the other hand is very pleasant but that's not a great thing to start. swim suggests doing the morphine any other way but iv as it isn't a good rush.

Diamorphine is metabolised into morphine, I beileve it is acetylated to cross the blood brain barrier faster. There is no difference is effects at all if used intra-venously.

[samuraigecko]

Originally Posted by rocksmokinmachine

Diamorphine is metabolised into morphine, I beileve it is acetylated to cross the blood brain barrier faster. There is no difference is effects at all if used intra-venously.

Just to quickly correct that. . It is actually de-acetylated at molecular position 3 to become bioactive as Morphine and 6MAM.

Hope this has been of help.

[rocksmokinmachine]

Originally Posted by samuraigecko

Just to quickly correct that. . It is actually de-acetylated at molecular position 3 to become bioactive as Morphine and 6MAM.

Hope this has been of help.

I meant in the manufacturing process it (morphine) is acetylated to cross the BBB more quickly.

I don't dispute anything else, though I was unaware of 6-monoacetylmorphine being involved. Thankyou for the clarification.

[samuraigecko]

Originally Posted by rocksmokinmachine

I meant in the manufacturing process it (morphine) is acetylated to cross the BBB more quickly.

I don't dispute anything else, though I was unaware of 6-monoacetylmorphine being involved. Thankyou for the clarification.

AHH yes, sorry that was SWIMs misunderstanding . . . SWIMs bad . . .

Morphine, as SWIYou correctly stated, is acetylated into heroin. Positions 3 and 6 in the free hydroxyl group of the morphine molecule are acetylated to produce 3,6DAM or diacetylmorphine (dual acetylated morphine, diamorphine, heroin).

The acetylation allows Heroin to pass the BBB more rapidly as SWIyou correctly stated. When it passes the blood brain barrier it is de-acetylated into mainly 6MAM and also plain Morphine. It is this rapid passing of the blood brain barrier which produces Heroins great "rush" effect and also why it is more effective when used for rapidly relieving pain in an ER situation in the countries whom still use it.

Sorry about that, one totally misunderstood SWIyour post and SWIyou are of course completely correct.

Hope this has been of help

[fnord]

gives a shitty pins and needles feeling that is uncomfortable

Many people love this feeling and its one of the main reasons they use morphine/hydromorphone.

as was said before 5 is a good place to start but some may feel 10-15 is a better dose.
Try 5 and see how you feel,then try another 5mg if your up to it,you can always do more drugs but you cant un-take drugs.