Is it safe to mix Piracetam with MAOIs?

[ethacetin]

I'm wondering if there are any contraindications between the Racetam family and MAOIs. For instance, if someone has been taking Piracetam daily for a few weeks and they want to use Peganum Harmala along with various Tryptamines, is this bad?

Piracetam looks like it would be oxidized by MAO enzymes..if this is true, taking an MAOI would temporarily result in the Piracetam not breaking down. Would this just make it more potent and amazing, or could this somehow result in toxicity, overdose, general unpleasantness, serotonin syndrome, etc?

And also, Piracetam is one of those things that works best used daily over a period of weeks. How long would one have to wait after ceasing Piracetam use before it's out of the system?

Thanks!

[Paracelsus]

There are no contraindications at all.

I have no idea how piracetam would interact with MAO, since MAO generally replaces the amine with a ketone, but the alpha-carbon is already quarternary so that's not going to happen.

Piracetam seems to be a nonspecific potentiator of many drugs - keep that in mind when babysitting someone contemplating taking various tryptamines.