What does Heroin do that other opiates don't? (like morphine, oxy, etc)

[mikebobjohn]

What does injected heroin do in the brain that other opiates do not? I mean why does it yield a more euphoric experience?

And, are there any prescription opiates that, taken orally, give a euphoric experience similar to that of heroin (when injected)?

[mikebobjohn]

Originally Posted by mikebobjohn

What does injected heroin do in the brain that other (orally taken***) opiates do not? I mean why does it yield a more euphoric experience?

And, are there any prescription opiates that, taken orally, give a euphoric experience similar to that of heroin (when injected)?

Basically, swim is looking to take something orally, and then have an experience similar to what he would experience if he injected heroin. Is there anything that's very similar? And if not, what's the closest one can get? Which prescription (oral) opiate?

[asaru969]

there is nothing that can compare to the feeling you get injecting heroin,sorry...injecting drugs is an experience all its own,although SWIM never ever would recommend injecting anything...one could try chewing an 80 mg oxy...

[psyche]

Heroin is diacetylmorphine. It is converted to morphine in the body. I think it passes the blood-brain barrier more efficiently because of the acetyl group and thus is able to get into brain more easily. Oxycontin and fentanyl are the closest things to heroin in prescription field, but SWIM isn't very familiar with these sort of things as he has never been even near of any of the the beforementioned. It is true that nothing orally compares to the rush that one can get from I.V:ing because the drug gets to the brain so much faster and any of it isn't destroyed by stomach of G.I tract.

[VincentVan]

In SWIM's (deep, long, life changing and awfully sad if sometimes illuminating) experience, absolutely nothing compares with intravenous injection of H.
True: diacetylmorphine once in a human body quickly degrades to morphine but still, if an H user is'nt in desperate conditions (in which case anything would do) he would'nt settle for anything less than the real thing.
SWIM found that , if one is prepared to forego the intial orgasmic rush, the most satisfing substitute is probably good quality opium taken orally; or smoked if one wants a faint reminder of the rush but could do without the longer term bliss sensation.

All this may sond tempting but you better keep always in mind that whoever falls in this sort of dreams is in for the rudest of awakenings.
Anyone who has had the time and the occasion to stare at this charming monster in the eyes would tell you the same thing: it just isn't worth it.
This is the only life you got.

VV
"They say you learn from your mistakes.
It's a lie.
My redemption has been staged numerous times
but the angels of passion still tail me in my sleep..."
(Vaya Con Dios - "Time Flies")

[samuraigecko]

Originally Posted by mikebobjohn

What does injected heroin do in the brain that other opiates do not? I mean why does it yield a more euphoric experience?

And, are there any prescription opiates that, taken orally, give a euphoric experience similar to that of heroin (when injected)?

To put it very simply . . .

Heroin (because of the dual acetylation at sites 3 and 6) passes the blood/brain barrier faster than other opiates. This is the most significant thing which Heroin does that other opiates cannot achieve.

(DiacetylMorphine is its real name, although SWIY may have seen it shortened to DiaMorphine which is basically just an abreviation - Di (2) Acetyl (acetylated) Morphine (duh. . HEH) . . basically meaning "dual acetylated Morphine" )

Because Heroin can get to the receptor sites so fast it has added advantages over Morphine and other opiates.

1] it can give a more instant pain relief. (useful for ER situations where INSTANT pain relief is needed and DiacetylMorphine is still used in hospitals in certain countries for this.)

2] because of its quickness in getting to the receptor sites it produces a better rush.

3] because it can get to the sites quicker it makes for a better FLOOD of opiates to the receptor sites giving a more profound euphoria quicker.

[NOTE: CAUTION is always advised when using opiates, but more especially street opiates as they can be of unpredictable strength. One should not use any of this information to influence ANY decision made by ones self]


Hope this has helped.

Reputation Comments on this post:

That's definitely more precise than my post, but when talkin' to someone likely to fall into temptation some kind of war...

[toighttoiger]

well the medical answer has to do with acetylation and being able to penetrate the BBB faster than other opiates. but it's really a lot more complicated than that, as anyone who has had a nice fling or two with it would tell you. one of the things that i always think of is the fact that depending on how quick you can cook up a shot, you can go from depressed to feeling like a million bucks in literally 5 minutes. nothing really compares to the simple power of that. that is why i have such a problem with it, because it's such a spontaneous thing to me.

but there has to be more than what i already mentioned, i hope other people in this thread can come up with more stuff. all i can tell you is that i haven't had a shot for almost a month, and i'm having fucking dreams about it. I have dreams about copping and shooting up, that right there is fucking ridiculous. like i said, there are a lot of factors at work that make it more complicated to understand, which i don't really still.

[samuraigecko]

1] everything said there was said above already.
2] one might want to not self incriminate.

Hope this has been of help