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Research Chemicals Piperazines, Phenethylamines, Tryptamines & other Research Chemicals or designer drugs.

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  #1  
Old 28-01-2005, 01:07
AZMEO2 AZMEO2 is offline
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The whole brain damage thing is a matter of perception. Goverment studies like to define damage as any change in function or chemistry. It is true that memory problems have been associated wit the use of MDMA but this is all short term. Read below:


MDMA (Ecstasy) and Holes in the Brain?


Dear Dr. Shulgin:


Lately I've been hearing a lot of talk about how every time you take ecstasy it does permanent damage to the brain. I've also heard that ecstasy puts holes in the brain. Are these statements true?


-- Road Dog


Dear Road Dog:


No, they are not. The "permanent brain damage" is based totally on studies done with experimental animals, with the findings extrapolated to encompass the human subject. In a simple statement, there have been no studies in man that have indicated brain damage.


The "holes in the brain" is an even more outrageous deception. These popular holes are areas in brain scans that appear less active in attracting radiolabelled agents that are agonists for certain receptor site areas. The pictures that are shown for comparison are not of the same person with or without MDMA in them, but of different people, one of whom has used a lot of ecstasy and the other one without any such history. The quintessence of this line of mythology is an article that appeared recently in the Willamette Week. It not only assured the reader that there were holes generated by serotonin loss, but that they became flooded with dopamine (the default neurotransmitter) and, being attacked by hydrogen peroxide, produced rust.


Sorry, drug warriors. No damage, no holes, no rust.


-- Dr. Shulgin
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  #2  
Old 28-01-2005, 04:54
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Quote:
Originally Posted by dmax
msimm: Yes, one recent study by a prominent mdma researcher at Johns
Hopkins University, George Ricaurte, was retracted because the chemical
they were administering turned out to be methamphetamine instead of
mdma. No study has yet conclusively proven that mdma has
neurotoxic effects in humans because to do so would involve disecting
the brains of humans who had recently been taking mdma. However,
memory loss, and poor performance on cognitive ability tests have been
found in mdma users. Also neurotoxic effects have been shown in
other primates. Erowid has archived many scientific journal
articles: http://www.erowid.org/chemicals/mdma/mdma_journal.shtml Other
articles are also in the section on mdma.



Basically, don't assume that mdma is safe because one study was
retracted, and don't assume mdma is dangerous because you read it
somewhere.




Quote:
Originally Posted by msimm


(I have known people with disturbing personality changes after chronic
long-term use, but a least the above study was seriously flawed.)



No worries, I wasn't assuming anything.

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  #3  
Old 01-02-2005, 20:46
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received EXPLOSION in the mail yesterday.

consumed at about 9pm.

starting feeling the effects at 9:10

was fully on by 9:30

amazing euphoric effects. similar to MDMA, but without the jaw tension. very giddy, and very happy. sensual and sexy energies flowing like. the air movement on my skin is even amazing.

total effects were gone by 1:30am. slept fine by 2:30am

This is absolutely an amazing chemical. I recomend anybody try it. Those of you who have not yet tried it, what are you waiting for? You have the ADMIN and PLATINUM MEMBERS of this forum saying it's great.

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  #4  
Old 01-02-2005, 22:18
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pinkawy.. have you tried methylone??? you make me curious to test this explotion =)



myself i took 100mg methylone.. and didn't find it particularry
interesting, eventhou there were effects.. there are plenty of other
better rc for lower price... whatever.. lot of people experience
methylone as mdma.. myself, i didn't.. the only mdma i have tried are
the indonesian valentines.. half pill is pretty strong already.




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Old 01-02-2005, 23:48
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It contains 280 mg. Surely becomes interesting then.
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Old 02-02-2005, 09:29
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100 mg of methylone is a threshhold dose.

i would suggest staring with at least 175-190mg.



Alfa, is the whole 280mg of methylone taken at once or is it split into a couple doses?


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  #7  
Old 02-02-2005, 20:29
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Depends if you are male or female, sensitive or not. If you'd take one xtc pill at once, you'd do the same here.
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Old 02-02-2005, 23:40
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So is this really 280mg of methylone? I try to stick to around 200mg of methylone as a starter, and boost as needed, but at any dose I don't find it really "better" than e, I feel it lacks the empathy and is more of just a pushy, social stimulant. The crash can be just as hard too. I've noticed some slight side effects which the medical community would label "toxicity" such as increased salivation (literally frothing at the mouth) and sometimes a sort of amnesia from methylone. While definetely better than MBDB, I would say it's better than molly.


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Old 02-02-2005, 23:44
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Quote:
Originally Posted by voogoo
I would say it's better than molly.

imeant wouldn't
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  #10  
Old 04-02-2005, 00:24
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Just wanted to let you guys know that SWIM ordered 10 Explosion vials and received them very promptly. The source is very reliable. Can't wait till this weekend!

Edited by: Alfa
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  #11  
Old 06-02-2005, 04:35
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I am curious about methylone and 'hangovers'-- so far, it seems
remarkably lacking in after-effects (except tiredness from lack of
sleep)-- has anyone found negative after-effects with persistent use?
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  #12  
Old 07-02-2005, 15:06
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I personally find the after afffects almost identical to MDxA, it´s just the high that differs... I´ve always felt VERY cracked out after methylone.
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Old 23-02-2005, 18:47
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Does anyone know who makes Explosion? Who owns the trademark?I have done extensive research to find the manufacturer but all I can find are retail outlets (smartshops) that sell it to end users or other retail outlets. I am not requesting a link to the website of the manufacturer. I am just wondering if other people have knowledge of this information (in which case I will continue my search) or if it is such a closlely guarded secret that know one knows.
Edited by: msumegi
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  #14  
Old 24-02-2005, 19:15
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I have two other questions regarding Explosion.


What are the effects of full vile as compaired to a half a vile ?


How long do the effects of a full vile last as compaired to half avile?

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  #15  
Old 24-02-2005, 21:38
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Advise from a smartshop:
For the first time use (prever woman) firstly take a half tube and as soon as the less becomes take the other half.

Advise from a girl at the dutch explosion topic:
Better to begin with a half tube, complete it later with a half.
While if I start with a half tube it come slowly up and can enjoy longer. (I will complete with always a half tube till at most totally 1.5 tube) go I as the fire department.

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  #16  
Old 25-02-2005, 02:38
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I tried explosion and found it similar to MDMA in some ways (sociability, warmth) but without the pushiness of MDMA.



It's a nice buzz, and leaves the head clear, but I did find three negatives:



1) It's double the price of MDMA (good MDMA in London = £40/gram = 8 doses = £5/dose. Methylone is around £10/dose.



2) It could induce a "hedonic treadmill" effect. I found that as the
methylone wore off, I wanted to use other substances. There have also
been a few trip reports on Erowid stating this:



http://www.erowid.org/experiences/exp.php?ID=27823



3) Some people (also from reports on Erowid) have experienced the "loss
of magic" effect from methylone, which is sometimes experienced after
50 doses or so of MDMA. With methylone, this appears to happen sooner.
This would mean that methylone would work better if it wasn't consumed
very often.



Despite the negatives, I enjoyed my Explosion experience. I just won't be doing it very often.


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Old 25-02-2005, 02:42
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Quote:
Originally Posted by voacanga
correct me if im wrong, but when people make up
misleading names for products, its cause they wanna take the truth
away


I agree, Voacanga. I think it is criminally irresponsible to sell
powerful experimental chemicals with the intent that they are
consumed.... and not be honest about what the contents of the vial are.
By all means, anyone should be free to sell anything they choose, but
to not print the ingredients on the label is sick. Someone could get
seriously hurt.

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Old 25-02-2005, 03:27
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Does this stuff alter your driving abilities? They say you shouldn't drive while on it but does it really cause imparment?
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Old 25-02-2005, 04:51
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its a psychoactive substance, so yes driving on it would be stupid.
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Old 26-02-2005, 00:09
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Yes, but it is safe to drive on amphetamines, especially if they are perscribed.
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Old 26-02-2005, 14:33
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The come up can make you feel a bit light headed and easilt distracted, so it's best to avoid anything during the 1st hour, but after that, you're pretty much fully functional (although you can get distracted if getting deep into a conversation)
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Old 26-02-2005, 22:44
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Can anyone tell me which Smartshops in Amsterdam sell Explosion ? I
guess I'm asking whether it is going to be difficult to get (under the
counter type stuff) or is it openly on display in most shops ? Also,
what the effects on sexual functioning ? Can it cause problems as MDMA
sometimes (not myelf of course .....)
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Old 27-02-2005, 06:50
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can someone please confirm once again that this is 280mg of methylone.

that sounds unreal to me. The flyer i read for it stated 180mg of EMM.
Now that we know the whole EMM thing was bullshit and that it is
actually methylone how has it jumped from 180 to 280mg?



Perhaps it was a typo earlier in the thread and what the poster meant to say was 180mg instead of 280mg.


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Old 27-02-2005, 07:12
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I also have been confused about the content of methylone. I have read that there is 280mgs and also that there is 250mgs. Could someone with direct knowledge please clear this up?
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Old 27-02-2005, 07:15
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Aslo if there are people who firmly believe that it is EMM, please post why.
Edited by: msumegi
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