Combinations - Alcohol and its synergy with stimulants

[f13nd]

When consumed with alcohol cocaine forms a new chemical in your body called cocathylene. The effect is apparently great potentiation of the euphoria. Also adds to heart strain i hear too tho. Atleast thats what i've read. Now, When alcohol is consumed in conjunction with amphetamines, do they form a new substance, because all ive heard about that combo is that amphetamines increase your ability to drink more and somewhat inhibit the sedating effects.

SO in my mind i see it as this. Coke and alcohol create a new more potent drug. I dont understand exactly how that works. I imagine if ones a depressant and ones a stimulant that they wouldnt enhance the coke...actually for that matter, is it an increase in the euphoria from both, enhanced coke buzz, or really drunk + really coked up feeling?

and with amps..do they just let your body break it down slower so it takes longer to get drunk? why no synergy here?

[thenightwatch]

I am unable to find any hard information online on the metabolic process that occurs when both amphetamine and alcohol are present in the liver.

However, SWIM has first hand experience with cocathylene and the effects it produces in comparison to just cocaine. Also, it is known that methylphenidate (a compound related to amphetamine, and somewhat related to cocaine) goes through a similar process in the liver in the presence of alcohol, and forms ethylphenidate, which is longer acting and has more Dopaminergic activity and less Norepinephrine/Noradrenilne activity than methylphenidate.

Subjectively, both combinations lead to stronger stimulation, enhanced euphoria, and increased alcohol tolerance.

SWIM also has experience in combining amphetamines with alcohol. SWIM would say, based on his completely SUBjective experiences, that amphetamines go through a similar process. This is based on the observation that alcohol combined with amphetamines also produces enhanced euphoria/duration of effects, and increased alcohol tolerance, in a similar way as cocaine+alcohol and methylphenidate+alcohol.

However, SWIM has absolutely no scientific basis for making this claim, SWIM just knows that the feelings of the three combinations differentiate from the effects of the stimulants alone in the same subjective way. Take it as SWIY will.

Reputation Comments on this post:

Thankyou for the info

[f13nd]

Seems strange that alcohol enhances stimulants. I can only imagine something to do with it increasing our ability to absorb them more efficiently i guess..
But what i mainly was wondering, does one get the effects of the alcohol at all when mixing? cause i cant imagine drunken tweaking being all that good...

[Kodi]

Metabolically, I havnt heard of a similar phenomenon occurring with amphetamines.

However, swim has similar subjective experiences as above, but would explain it a different way. He would say that the amphetamine effects just mask certain effects of alcohol. For SWIM, when he gets drunk he sometimes gets nauseous, tired, spinning feeling. And for him, amphetamines mask these unpleasant side effects of alcohol so the pleasurable ones are more prominent.

[Lethargy]

SWIM does not enjoy alcohol particularly, but the last two times he drank and enjoyed it he had a bunch of Adderall in his system as well. He doesn't know about any chemical alterations but as mentioned above, he feels the amphetamine masks what he perceives as negative effects of alcohol (lethargy, nausea, slowed cognition, loss of coordination...) and synergizes nicely with the effects of alcohol that he enjoys (lower inhibitions, easy conversation, slight euphoria.)

He actually decided after the last experience that he would only get drunk while on amphetamines, and since he doesn't trust street amps he has yet to get drunk again.

Actually after SWIM told me his story, I remembered a snippet of a Chemical Dependency class I took some years back, the professor mentioned that mixing amphetamines and alcohol altered the metabolism to form a greater concentration or different form of -aldehyde than usually formed from alcohol use alone. Alas I cannot remember the specific name, only that he compared it to formaldehyde.