Fentanyl

[Angrytelepath17]

Swim is finallly getting prescribed some Duragesic fentanyl 12.5 micrograms/h patchs. Swim is wondering if these things are any good. Also, if one wanted to get an increased effect from one of these, SWIM has read that there are ways to take the gel off of the patch and either shoot or smoke it. Does anyone know anything about this? Can anyone give any information and recommendations about this? My friend would definitely wouldn't inject, but would smoking the gel give a better effect?
Information please.

Also, if someone can point swim in the direction of a recipe/guide for making fentanyl with standard chemestry products and/or poppy pods, seeds, or cooked flake opium, that would be very helpful

[samuraigecko]

wiki data

Fentanyl is an opioid analgesic, first synthesized by Janssen Pharmaceutica (Belgium) in the late 1950s, with a potency eighty times that of morphine. Fentanyl was introduced into medical practice in the 1960s as an intravenous anesthetic under the trade name of Sublimaze. Fentanyl has an LD50 of 3.1 milligrams per kilogram in rats, and, 0.03 milligrams per kilogram in monkeys. The LD50 in humans, by intravenous injection, is 0.2-1 milligrams. In the United States, fentanyl is a Schedule II drug.

Chemical data Formula C22H28N2O Mol. mass 336.471 g/mol Physical data Melt. point 87.5 °C (190 °F) Pharmacokinetic data Bioavailability 92% (transdermal)
50% (buccal) Protein binding 80-85% Metabolism hepatic, primarily by CYP3A4 Half life 7 hours (range 3–12 h) Excretion Urine

[Angrytelepath17]

thanks for the wiki data but ive already read that. im curious about how some people have used the patches, what its like to be on them, etc etc.

[trptamene]

Fentanyl experiences

There isn't much there, but would be the place to look... Also, try the vaults of erowid they usually have a few trip reports

[samuraigecko]

Originally Posted by Angrytelepath17

Swim is finallly getting prescribed some Duragesic fentanyl 12.5 micrograms/h patchs. Swim is wondering if these things are any good. Also, if one wanted to get an increased effect from one of these, SWIM has read that there are ways to take the gel off of the patch and either shoot or smoke it. Does anyone know anything about this? Can anyone give any information and recommendations about this? My friend would definitely wouldn't inject, but would smoking the gel give a better effect?
Information please.

Also, if someone can point swim in the direction of a recipe/guide for making fentanyl with standard chemestry products and/or poppy pods, seeds, or cooked flake opium, that would be very helpful

Since fentanyl is a synthetic opiate one seriously doubts that there would be a way to synthesize it from opium for a number of reasons.

If it was possible to do so one would think that many would already be doing it since it is supposed to be like 80 times the potency of morphine. One will do a little more research and find out BUT one is pretty sure it is a fully chemical and complicated process. (one could be wrong though so any one else's input is always welcomed)

[samuraigecko]

you may want to look at THIS too

Hope that helps in some way.

[Angrytelepath17]

So it's not even a real opiate? Damn doctor. Never giving me the real deal. ARGHH!!!!!

[samuraigecko]

err. . SWIY said he read the wiki data
it IS an opiate.
its just that its a VERY powerful SYNTHETIC (man made) one.
mainly used as an operating room anesthetic and analgesic, it can have different synthesis including one that is 10,000 times more potent than Morphine (which is used to anesthetize or immobilize large animals).

Since the chemical makeup of Fentanyl is totally synthetic and does not even use a natural opioid as a starting point for synthesis like Hydro/Oxy Codones do, one HIGHLY doubts that one would be able to make this from any type of raw opium.

quick analysis:
all notes taken from wiki data which SWIY may have overlooked.

(N-phenyl-N-(1-phenethyl-4-piperidinyl)propanamide) by Janssen Pharmaceutica was achieved in four steps, starting from 4-piperidinone hydrochloride. The 4-piperidinone hydrochloride was first reacted with phenethyl bromide to give N-phenethyl-4-piperidinone (NPP). Treatment of the NPP intermediate with aniline followed by reduction with sodium borohydride afforded 4-anilino-N-phenethyl-piperidine (ANPP). finally ANPP and propionic anhydride are reacted to form the amide product.

NOTE: no naturally occurring opioid was used for a "starting point" such as the Thebaine used to synthesize Hydro/Oxy Codones.

To date, over 12 different analogues of fentanyl have been produced clandestinely and identified in the U.S. drug traffic. The biological effects of the fentanyls are similar to those of heroin, with the exception that there is a noticeably less euphoric 'high' associated with the drug and a stronger sedative and analgesic effect. Because the effects of fentanyl last for only a very short time, it is even more addictive than heroin, and regular users may become addicted very quickly. Additionally, fentanyl may be hundreds of times more potent than street heroin, and tends to produce significantly worse respiratory depression, making it somewhat more dangerous than heroin to users — though in some places, it is sold as heroin, often leading to overdoses.

One would be inclined to suggest caution in this matter considering the dangers to health involved and also be inclined to suggest non-usage if for recreational purposes because it does not produce the HIGH.

One hopes that this has helped in some way.

[crunchyblack]

Originally Posted by Angrytelepath17

So it's not even a real opiate? Damn doctor. Never giving me the real deal. ARGHH!!!!!

LOL dude you have the strongest shit allowed to be prescribed. Be careful with that shit because it ain't no joke and has killed alot of people who were careless.

[CosmosSurfer]

Fentanyl is the most potent synthetic opiate prescribed. Are your patches q72 or...?
Crunchyblack is correct, the stuff is incredibly powerful and has caused many many many deaths by overdose. It's actually been used to cut heroin , causing the consumers to o.d. due to their ignorance of the cut..careful and use responsibly and moderately.

[Psych0naut]

Originally Posted by Angrytelepath17

So it's not even a real opiate? Damn doctor. Never giving me the real deal. ARGHH!!!!!

Chemicals that bind to the mu-opioid receptors are known as opioids. Only the opioids that naturally occur in the papaver somniferum(opium poppy) are called opiates. Any painkiller except for morphine and codeine are not opiates, but opioids.

Fentanyl is difficult to synthesise, one needs a proper labaratory setup to do this. It's, as mentioned above, not made from opiate alkaloids like the semi-synthetic opioids; oxycodone and hydrocodone are made of. The starting precursor for the synthesis of fentanyl is 4-piperidone. It's a 3 or 4 step synthesis to Fentanyl, with very high yields, but the precursors are hard to aquire, and thankfully one needs to have a good knowledge of organic chemistry to be able to synthesis it.

Reputation Comments on this post:

Great bit of clarification regarding the opiate/opiod terminology. Good job.

[OhCasey]

Originally Posted by Psych0naut

Chemicals that bind to the mu-opioid receptors are known as opioids. Only the opioids that naturally occur in the papaver somniferum(opium poppy) are called opiates. Any painkiller except for morphine and codeine are not opiates, but opioids.

Fentanyl is difficult to synthesise, one needs a proper labaratory setup to do this. It's, as mentioned above, not made from opiate alkaloids like the semi-synthetic opioids; oxycodone and hydrocodone are made of. The starting precursor for the synthesis of fentanyl is 4-piperidone. It's a 3 or 4 step synthesis to Fentanyl, with very high yields, but the precursors are hard to aquire, and thankfully one needs to have a good knowledge of organic chemistry to be able to synthesis it.

I wonder just how difficult it would be to make fentanyl from opium. Considering all the steps it probably wouldnt be plausible for a small time grower of poppies but could you imagine some big illegal middle eastern poppy farmers getting some starting capital to turn that opium to fent and maybe even stamp it into sublingual pills and sending it this way instead of the Big H.

Reputation Comments on this post:

Learn to read the thread before posting.

[Ethyl]

Why don't u read a little on the subject or the posts before putting stupid coments and questions in some posts. Talk is cheap and more cheaper than that is impossible..

Fent is not made from opium nor will ever be, just fucking read on the subject first before putting such shitty comments..

The amount of posts that futile, false, and nonsense that one gets in forums that the topic is drugs leads to one thinking that drug users are mostly like that...

How can a knowadge grow in this way?

Reputation Comments on this post:

The flaming isn't necessary, but Swim agrees

[Ethyl]

Originally Posted by Psych0naut

It's a 3 or 4 step synthesis to Fentanyl, with very high yields, but the precursors are hard to aquire, and thankfully one needs to have a good knowledge of organic chemistry to be able to synthesis it.

Thank god for that. But in the other face of the coin, i wouldn't mind if illegal made fent were more available! I never tried it.

[dna_1977]

Originally Posted by Ethyl

Why don't u read a little on the subject or the posts before putting stupid coments and questions in some posts. Talk is cheap and more cheaper than that is impossible..

Fent is not made from opium nor will ever be, just fucking read on the subject first before putting such shitty comments..

The amount of posts that futile, false, and nonsense that one gets in forums that the topic is drugs leads to one thinking that drug users are mostly like that...

How can a knowadge grow in this way?

hehehehehe.....não te chateies homem!!....

abraço

[Orchid_Suspiria]

Why would someone complain about getting fentanyl instead of a natural opiate?Fentanyl is better than most the natural opiates,certainly stronger.Wearing a fentanyl patch is like three days of fun for swim.And please those with no opioid tolerance please don't even think of trying fentanyl!Swim doesn't want to see anyone in the hospital or worse.

[waltz#2]

SWIM's friend got it while they were pregnant. SWIM's friend claimed it was the best thing in the whole world, perhaps because it relieved the pain, perhaps because it really is the best thing ever, SWIM will most likely never know.

It only takes a small amount of searching on here to get 95% of the answers any SWIMMER is looking for.

http://www.drugs-forum.com/forum/sho...light=fentanyl

None of those chemicals occur in any poppy plant. It would be best not to (pardon the phrase) fuck with fentanyl. Even after cutting heavily, a slight breeze when measuring the initial pure product could be the difference between (as SWISG puts it) hearing the ambulance coming to pick you up, or worse not hearing it at all.

Ultra strong semi-synthetics can be derived from regular M, at least wikipedia seems to think so
"Replacement of the N-methyl group of morphine with an N-phenylethyl group results in a product that is 18 times more powerful than morphine in its opiate agonist potency.[citation needed] Combining this modification with the replacement of the 6-hydroxyl with a 6-methylene produces a compound some 1440 times more potent than morphine,[citation needed] stronger than the Bentley compounds such as etorphine."

SWIM is pretty sure some SWIMMER on this board knows exactly what SWIY would need to do this. Again, a significant increase in strength requires a significantly higher accuracy scale. No, the ones at your local head shop aren't going to do it.

SWIM slept through his O-chem classes, this is all garbage to him anyways.

[Ethyl]

Originally Posted by dna_1977

hehehehehe.....não te chateies homem!!....

abraço

A neura no dia era grande..

Abraxao!

+- Translation:

Was in a bad mood..

a big hug!

[vantranist]

I doubt anyone has pure Fentanyl to messure out anyways.

And if they did you could dose Much much safer when in solution with larger amounts of water... Please make sure u know what you're doing tho.

[truth]

SWIM just got 3 75 mcg/hr Fentanyl Patches

its says Delivery of 75 mcg/hr Fentanyl for 72 hours.

Now SWIM would like to know if this is high of a dose?
And if SWIM would die from just putting one on?
SWIM has a tolerance of about 120 mg of oxy
or 60 mg of Hydrocodone

EDIT:SWIM found out 75 is perfect for SWIM =)

[gw1951]

My friend started out on 25mcg and he is now up to 50mcg, additionally his dr prescribed Oxycodone 15mg immediate release. My friend said that after the 72 hours are up, he rolls the used patch like a doobie and snips one ends and smears the goo on his inner arm for added relief. The Oxy's are right on time, says my friend.

gw1951 added 5 Minutes and 11 Seconds later...

My friend reports he gets absolutely no nasty side effects from the Fentanyl (like a buzz or anything near one) but he does get relief from the degenerative disk desease.

[Solinari]

I had a look at a PDF called Fatal Intravenous Fentanyl Abuse, scary stuff. It also mentions people dying from eating the patches and smoking them. In fact it talks of one person being revived after smoking a patch, then later dying from doing the same thing again.

Very dodgy drug to fuck around with, not to be toyed with.