What is tramadol??

[gibsonUSA]

SWIM just picked up some pills with 30mg' ACET and 36.5 MG of tramadol.. does anyone know what tramadol is or if it is any good? or if SWIM can do a CWE on it??? any information would really help SWIM

[trptamene]

UTFSE...there is loads of information on tramadol. I've never heard of doing a CWE extraction on tramadol/apap, but at 30mg a pop one shouldn't really worry about it too much considering a good starting dose of tramadol is 50mg, and the maximum daily dose is 400 mg (corresponding to 400/36.5 x 30 = 328mg acetomenophen maximum daily dosage if this is only source of acetominophen)...this is about the same as a single tylenol.

Are you sure it is only 30mg, that seems kind of low, what about 300mg?

tramadol also has an unusually high rate of non-responders so you're lab rat may not get the same effects as others.

I was prescribed tramadol (not w/ apap) for backpain for over a year, it is a very good drug IMHO, but is physically addictive unlike how it is marketed as being non-addictive. It gave a slight stimulant effect at lower doses and at higher doses (increased by my doctor) this seemed became more pronounced.

The bad part is that it made me dependent on the drug, I had to have ultram in my system or I was entirely useless. Couldn't study worth crap, very irritable and felt like shit. Also, orgasms on tramadol were quite difficult to achieve causing problems between me and my sig. other.

[KBLSD]

Originally Posted by trptamene

UTFSE...there is loads of information on tramadol. I've never heard of doing a CWE extraction on tramadol/apap, but at 30mg a pop one shouldn't really worry about it too much considering a good starting dose of tramadol is 50mg, and the maximum daily dose is 400 mg (corresponding to 400/36.5 x 30 = 328mg acetomenophen maximum daily dosage if this is only source of acetominophen)...this is about the same as a single tylenol.

Are you sure it is only 30mg, that seems kind of low, what about 300mg?

tramadol also has an unusually high rate of non-responders so you're lab rat may not get the same effects as others.

I was prescribed tramadol (not w/ apap) for backpain for over a year, it is a very good drug IMHO, but is physically addictive unlike how it is marketed as being non-addictive. It gave a slight stimulant effect at lower doses and at higher doses (increased by my doctor) this seemed became more pronounced.

The bad part is that it made me dependent on the drug, I had to have ultram in my system or I was entirely useless. Couldn't study worth crap, very irritable and felt like shit. Also, orgasms on tramadol were quite difficult to achieve causing problems between me and my sig. other.

thats fuck up swim has a extremely hard time achieving orgasms on tramadol too since swim uses protection it is even harder swim hates that effect

[Mint boi]

He probably meant 300mg.
30 mg would serve no purpose!

[trptamene]

^^Ya, I just went back and edited this after it hit me this made no sense.

[Ale]

Considering that the guy who posted the thread is in North America those must be the so called Ultracet® pills,which combines two analgesics:Tramadol Hydrochloride (37.5 mg) and Acetaminophen/Paracetamol(325 mg).that'll most likely be the case IMO.

Reputation Comments on this post:

good insight on the likely pill type and ingredients/dosage

[chico]

it addictive long term because it boost serotonin. Just like being on paxil, prozac, etc if on longer than a year get major withdraw symptoms.....short term waste of time IMOP, better off pounding a bottle of robitussin dm

[donzen]

sry for offtread but here is my tramadol story and what i think about it.

When i went to the dentist more than a year ago she took out my wisdom teeth and wanted to give me paracetamol.. i said that would not work for me so she gave me my first 5 tabs tramadol 150 retard- that was my introduction to opiates and i loved it from the first day. then i had serious "problems" with my teeth and got a regular prescription for 50 x 150mg retard every 2 weeks . So i got addicted to that stuff
first my girlfriend and i had to take a half tab to get high but after a week or so we already needed a whole one to feel anything and so on.
Now after a year or so we need about 3-4 a day to get no withdrawal symtoms and i still get my regular prescriptions without having problems with my teeth anymore.
If you are living in Germany and you are a private patient you have many priveleges
(even some that suck)

Its very easy to take DHC or Codeine instead of tramadol and after 2 weeks on codeine you can even actually feel something again.

Its very hard to get an orgasm on tramadol but when you have one it feels just unbelievable, especially for the girlfriend.

treads and doctors say that tramadol does not combine with most nice drugs, but after more than a year of research SWIM knows that there are nearly no bad interactions

best regards
donZen

[donzen]

Originally Posted by donzen

sry for offtread but here is my tramadol story and what i think about it.

When i went to the dentist more than a year ago she took out my wisdom teeth and wanted to give me paracetamol.. i said that would not work for me so she gave me my first 5 tabs tramadol 150 retard- that was my introduction to opiates and i loved it from the first day. then i had serious "problems" with my teeth and got a regular prescription for 50 x 150mg retard every 2 weeks . So i got addicted to that stuff
first my girlfriend and i had to take a half tab to get high but after a week or so we already needed a whole one to feel anything and so on.
Now after a year or so we need about 3-4 a day to get no withdrawal symtoms and i still get my regular prescriptions without having problems with my teeth anymore.
If you are living in Germany and you are a private patient you have many priveleges
(even some that suck)

Its very easy to take DHC or Codeine instead of tramadol and after 2 weeks on codeine you can even actually feel something again.

Its very hard to get an orgasm on tramadol but when you have one it feels just unbelievable, especially for the girlfriend.

treads and doctors say that tramadol does not combine with most nice drugs, but after more than a year of research SWIM knows that there are nearly no bad interactions

best regards
donZen

Sorry for my bad language skills
I have to say i like this place very much its just great here

[Ryu]

SWIM is staring at a 30 pack of europe strenght 50mg tramadol hydrochloride. SWIM would also like to convey his total dislike of this substance and inform of its lack of fun and serious propensity to cause major constipation and haemroids. Dont even bother with this unless you are seriously desperate or curious, its not even fun.

[heroin_ed]

Originally Posted by Ryu

SWIM is staring at a 30 pack of europe strenght 50mg tramadol hydrochloride. SWIM would also like to convey his total dislike of this substance and inform of its lack of fun and serious propensity to cause major constipation and haemroids. Dont even bother with this unless you are seriously desperate or curious, its not even fun.

'nuff said.

Tramadol is the worst opioid known to man.

[Melalicious]

swim has had "tramal" before, but made the big mistake those many years ago, of not knowing what she was taking!! swim took the 200mg tablets, without knowing/realising they were the 200mg instead of the 50mg, bcoz she had NO idea about the drug at the time,and received them from a friend, long story short, swim swallowed 4 of the 200mg Tramal tablets over, lets just say not a very long time! and was vomiting and EXTEMELY ill for a good 6 hours straight, nothing but throwing up! a puff of a smoke would enduce the vomiting, not even weed would stop swim from being sick! swim had to let her body ride it out!

althought swim did feel fantastic for a cpl of hours before all the sickness started, it definatly was one of swims most stupiest mistakes!

swim is very lucky she got it out of her system enough to not do serious instant damage!

so guess swims point here is, PLEASE BE CAREFUL AND READ AND RESEARCH EVERYTHING CAREFULLY BEFORE CONSUMING!


thats why swim loves this forum so much, fantastic info, amd great swimers

[trptamene]

Originally Posted by Melalicious

swim has had "tramal" before, but made the big mistake those many years ago, of not knowing what she was taking!! swim took the 200mg tablets, without knowing/realising they were the 200mg instead of the 50mg, bcoz she had NO idea about the drug at the time,and received them from a friend, long story short, swim swallowed 4 of the 200mg Tramal tablets over, lets just say not a very long time! and was vomiting and EXTEMELY ill for a good 6 hours straight, nothing but throwing up! a puff of a smoke would enduce the vomiting, not even weed would stop swim from being sick! swim had to let her body ride it out!

althought swim did feel fantastic for a cpl of hours before all the sickness started, it definatly was one of swims most stupiest mistakes!

swim is very lucky she got it out of her system enough to not do serious instant damage!

so guess swims point here is, PLEASE BE CAREFUL AND READ AND RESEARCH EVERYTHING CAREFULLY BEFORE CONSUMING!


thats why swim loves this forum so much, fantastic info, amd great swimers

WOW!! Glad to hear everyone is oK! 800 mg tramadol sounds extremely nauseating even to me and I've taken up to 400mg w/ a doctor's prescription.

It should be noted the maximum indicated daily dose for this drug is 400mg. Swiy would be careful about trusting that friend again as he should've told swiy and made it clear not to take all four.

[yaba]

Swim is on tramadol he gets about 60 a month from his doc and loves them!! They give swim a nice relaxed high he usual start with 4x50mg and the same dose 2-3 hours later. Not everyone likes them, But both swim and some of his friends love them.

[Paracelsus]

"Known to me" would've been more exact, am I correct?

[heroin_ed]

There's a myriad of opioids out there.

How are you gonna tell SWIM that tramadol is better than other opioids such as morphine, hydromorphone, heroin, oxycodone.... the list could go on. Even other atypical opioids such as pethidine, fentanyl and methadone blow tramadol out of the water. Hell, SWIM would take codeine over tramadol. SWIM isn't trying to be a douche, it's just if there is an opioid that does not give a better feeling than tramadol, SWIM would love to know.

[testodan]

SWIM has taken up to 2.000mg of Tramadol capsules,(brand name Tramquel/Tramadol SR),with two days hangover though.He usually takes up to 1.000 mg the least.He has never done any other opiate though,besides Kratom which has a high tolerance on .

[trptamene]

1000-2000mg of tramadol is a bad idea for the great majority of uses. Above 400mg, nasty side fx involving brain chemistry become apparant.

[testodan]

Originally Posted by trptamene

Above 400mg, nasty side fx involving brain chemistry become apparant.

Trptamene,
What SWIY mean by that,any relation on nerve cells' damage in these dosages?

[yaba]

1000-2000mg is a very large dose. Swim done about 1000-1200mg once, or he thinks. and had a bad experiance... He now wouldn't exceed 300mg without a drink or 200mg with a drink.

If he is in pain he will take more but will spread it throughout the day.

[trptamene]

Originally Posted by Nursing2005 Drug Handbook

INDICATIONS & DOSAGES
Moderate to moderately sever pain
Adults: Initially, 25 mg P.O in the morning. Adjust by 25 mg q 3 days to 100 mg/day (25 mg q.i.d.). Thereafter, adjust by 50 mg q 3 days to reach 200mg/day (50 mg q.i.d.). Thereafter, give 50 to 100 mg P.O. q 4 to 6 hours, p.r.n. Maximum, 400 mg daily.
Elderly Patients
For patients older than age 75, maximum is 300 mg daily in divided doses.

Adjust-a-dose: For renally impaired patients with creatinine clearance below 30ml/min, increase dose interval to q 12 hours; maximum is 200 mg daily. For patients with cirrhosis, give 40 mg q 12 hours.

ACTION
Unknown. A centrally acting synthetic analgesic compound not chemically related to opiates. Thought to bind to opiod receptors and inhibit reuptake of norepinephrine and serotonin.

So it has some SNRI activity then, as we know. I thought was SSRI, but apparantly me and a few others were mistaken.

Originally Posted by Nursing2005 Drug Handbook

ADVERSE REACTIONS
CNS: dizziness, vertigo, headache, somnolence, CNS stimulation, asthenia, anxiety, confusion, coordination disturbance, euphoria, nervousness, sleep disorder, seizures, malaise.
CV: vasodilation
EENT: visual disturbances
GI: nausea, constipation, vomiting, dyspepsia, dry mouth, diarrhea, abdominal pain, anorexia, flatuence.
GU: urine retention, urinary frequency, menopausel symptoms, proteinuria.
Muscoskeletal: hypertonia.
Respiratory: respiratory depression.
Skin: pruritus, diaphoresis, rash.

Reactions may be common, uncommon, life-threatening, or COMMON AND LIFE-THREATENING.

What I want to stress is the 400 mg maximum daily dose! This is the dose for a 24 hour period! So 8 50 mg tramadol per day guys! YOU DON'T WANT TO TAKE MORE, TRUST ME! Nasty side fx certainly come out when you don't respect this. Esp. do not excede it for days in a row doing some sort of ultram benge, I do not think doing it a few times spread apart would cause too many problems...

[tigger]

Swim has been taking Tramadol 400/500mg daily for about a year now, swim is definitly dependent on it, swims doctor told him there was a very low chance of dependency which is a lie. so just be careful people swim always thought he would not be silly enough to be dependent on a drug but it happend, and its hard to stop. just be carfull people.

[samuraigecko]

What is tramadol?

Tramadol is classed as a quasi-opioid, but has more in common with a anti-depressant rather than an opiate. (This is not to say that it is not effective on pain, as is reported it seems to be an extremely good pain killer in a fair percentage of people).

Tramadol by itself has almost no affinity for mu-opioid receptors but its metabolite has a moderate affinity for those said receptors.

Tramadol also acts as an SSRI, NARI and MOA thus indicating to one that it may have more in relation to an anti depressant than an opiate. (As a chemical only not necessarily in its action).

Tramadol is most commonly prescribed in either a 50mg instant release or 100mg sustained release capsule but is also available in other forms and dosages.

It is used medically as a moderate pain killer but also for people with "phantom pain" (I.E: a pain in which the cause cannot be determined by medical examinations or imaging). This also seems effective and can also indicate a mood elevation which would help to alleviate a phantom pain in either genuine or hypochondria cases. (More research and proof is needed for this though, it is not solid fact).

A friend of SWIM has a rare bone disorder and is prescribed Tramadol. This particular bone disorder is quite painful as it cases bones to grow outward rather than upward. It also causes bone to grow outward from any break or bruising on the bone when an injury occurs.

Tramadol was quite effective for him to start with and made it so that he was at least able to walk (though not well, he has a permanent "limp" like gait to his walk, he has actually been arrested for "drunk in a public place" when he was completely sober just because of the way he has to walk).

The Tramadol now however is no longer effective for him and he now has to be re-evaluated by a pain management clinic so he can be cleared for a prescription for something more effective. This would seem to indicate not only an easily built tolerance to Tramadol but also an acquired immunity perhaps if it is possible for such a thing to occur.

Example: this guy can take a whole packet of Tramadol and it "only just" takes the edge off so he can walk semi-normal (using the term semi-normal loosely). This sort of dosage would almost certainly OD the average person and even produce the dreaded side effects of Tramadol, none of which has ever occurred in him (which is the reason for the speculation of perhaps some kind of acquired immunity, it would be interesting to hear anyone else's thoughts or experiences concerning this point).

In short it SEEMS that Tramadol is a low potency quasi-opioid (fully synthetic) that also has SSRI, NARI and MOA properties. this is not to say that it is not addictive. Any substance is addictive. Even joggers get "addicted" to the endorphin release caused by simple bodily exertion.

(The reasoning for the comment on "low potency opioid" is because such high dosages are needed to achieve a recreational dosage in the majority of people when compared to other opioids / opiates such as Oxycodone, Hydrocodone, Oxymorphone etc.)

Hope this description of Tramadol has helped. One can see more at Wiki . . .
Click the TRAMADOL.