How much Acetaminophen is ok to take?

[Nickoteen]

SWIM has Tylenol 3's.Swim doesnt take them often but SWIM wants to take some now without doing the CWE.Is it ok for SWIM to take 1800mg of Acetaminophen if he rarely takes Acetaminophen?

Whats the limit SWIM should stay under for occasional use?

[fnord]

CWE's are quick and easy.why not take the few minutes to do it?

[Nickoteen]

Originally Posted by fnord

CWE's are quick and easy.why not take the few minutes to do it?

SWIM has never done it before.SWIM will go read up more on it

[pixplzthx]

Here's a study I found

1800 mg isn't too much but keep in mind that large doses of acetaminophen can leave one feeling "icky". So don't harsh your buzz and take a little time to get rid of as much acetaminophen as possible.

[trptamene]

1800 mg rarely should cause little harm to someone that is not allegic to the drug.

I read somewhere that the toxic dose would be 10g in a day, but when one starts to push the 4+ g range they should seriously consider what they're doing to their liver.

Follow the advice above...look into a CWE...

even if the tylenol isnt bad...it taints the opiate high in swims opinion (particularly at higher doses).

[fnord]

still an CWE should be done anyways, even if it is a safe amount.the cleaner,the purer,the better,the safer. what if someone ended up drinking without doing a CWE?and anyways id assume any large amount of acetaminophen would be bad for someones liver.

theres no excuse for not doing a CWE its quick and simple and needs nothing but some water coffee filter and the ability to follow simple directions.

[Nickoteen]

Originally Posted by fnord

still an CWE should be done anyways, even if it is a safe amount.the cleaner,the purer,the better,the safer. what if someone ended up drinking without doing a CWE?and anyways id assume any large amount of acetaminophen would be bad for someones liver.

theres no excuse for not doing a CWE its quick and simple and needs nothing but some water coffee filter and the ability to follow simple directions.

Its take an hour or more doesnt it?

[Jatelka]

It's simple folks.

No More than 4g Paracetamol (acetominithingy) in 24 hours. Less if alcohol or other drugs affecting the liver are taken, or if there is liver damage from other sources (Eg: Hepatitis).

SWIJ has seen a 16 year old girl with fulminant liver failure from paracetamol after taking only 5.5g.

Liver failure is a terrible way to die: Yellow, encephalopathic, deranged clotting leading to bleeding from every orifice, kidneys shutting down...

There's really no excuse

[Mint boi]

Originally Posted by Jatelka

Less if alcohol or other drugs affecting the liver are taken

This is a very important point. The amount of paracetamol the liver can take can be almost halved if one is taking enzyme inducing drugs like St Johns Wort, or if one frequently consumes more than the "rda " of alcohol.

Might be a good idea to make a sticky thread giving info on paracetamol toxicity ect, as alot of posts pop up here ever so often on this subject? If a mod thinks this is a good idea I can start the ball rolling!

Its take an hour or more doesnt it?

My ferrets take about 30min from start to finish

[oxyaddict420]

SWIM just got back from the E.R about an hour ago after taking 17,500 in 26 hours time! This is no lie!! Go check the other liver repair thread for details before he went, and how scared he SWIM was!! SWIM is back home after only a couple of hours at the E.R and they ran blood tests on him, and urine tests.. EVERYTHING came back 100% perfect! They monitored SWIM for hours but didn't give him anything to counteract it or anything.. As a matter of fact the DR. himself told SWIM that since he was a 300lb man that he didn't even ingest enough to be lethal.. He broke it down into ml per kilo or some technical crap.. Bottom line SWIM is ALIVE and WELL..

SWIM reccommends this high of dose to KNOW-ONE!!!! SWIM was very lucky and thanks god for not having liver failure! SWIM has also at many other times taken over 20,000mg of tylenol 3-4 days in a row even.. SWIM technically should be dead, but thankfully isnt!

p.s- The D.R from the E.R that was told the 100% truth about SWIM taking 35 5/500 vicodion in 26 hours,, after wrote a script for #20 of oxycodone IR..NO TYLENOL! SwIM had to tell him the drug name as he looked it up in his medical book.. ONLY IN AMERICA

[ironmics]

Kind of offtopic, but the ceiling effect for codeine is around 200mg right? Which would be around 2.1g APAP. If taking that much anyway, I would definitely say to avoid alcohol completely mixing that much codeine or APAP with alcohol could be bad. APAP can also cause long term liver damage in much smaller doses, and since liver enzymes can vary so drastically from person to person it's tough to say how much is safe in the long run.

On another side note, I'd really be interested in the effects of grapefruit juice and tagamet on the toxicity of APAP. Since tagamet should be able inhibit the enzymes which cause the harmful effects of APAP. Plus, in swim's opinion anyway, grapefruit juice at least doesn't hurt a codeine buzz and thinks it actually helps. Could just be placebo, but I've never found a consensus about it. Also IR OXY is a crazy find, swims seen 10mg pure once and had a couple. Careful with that though, if your name was just a joke before, it won't be after swiy's done with that bottle.

[oxyaddict420]

Nothing joking about the name brotha.. That bottle of 20 5mg oxy IR is gone.. was gone in 4 doses...

[Mint boi]

Originally Posted by ironmics

ceiling effect for codeine is around 200mg right?

400mg more like