Weekly usage

[acetylene]

SWIM has recently been using peyote every week. Is there a long term health effect to this? SWIM heard about the goldfish study that concluded that mescaline causes dopamine deficiency...

[Samadhi]

every drug has an effect on the brain...
the cacti is a beautiful thing. one should not abuse it by doing it once a week. space it out and let your mind and brain chemistry bounce back before doing it.

BTW: Swim is happy to hear SOMEONE still uses good ol' peyote. Just be aware that mescaline has been shown to have a negative effect on the brain when abused (like any hallucinogen)

[meep]

How is swiy getting that amount of peyote?!

*jealous*

[acetylene]

one of swim's friends belongs to the native american church..

swim will just take a tiny bit instead of a full dose this week. then he will space out his usage.

[Samadhi]

that sounds good
lets not abuse the beautiful cacti

[wendel]

The first time I ate cactus I thought "hey, I should do this everyday." Life was awesome. But I know that is a bad idea.

[Richi]

Wikipedia says that a tolerance develops with constant use. This means mescaline is changing something permanently...

[Mint boi]

tolerance does not mean permanent change

[Richi]

Originally Posted by mint boi

tolerance does not mean permanent change

How about if it is permanent tolerance?

[Shampoo]

Permanent tolerance implies permanent usage, or permanent neurotransmitter production damage. Mescaline has been shown over long periods of time, and in relatively high doses, to cause dopamine-withdrawal syndrome, though this commonly clears up within a few days. swimy last peyote experience lasted through about a month, with doses administered every 48 hours. Outside of the inherent psychological change caused by any experience (drug-induced or otherwise), the permanent psychological impact seems negligible if existent at all.

As for samadhi123, please provide some evidence that "mescaline has been shown to have a negative effect on the brain when abused (like any hallucinogen)" Thats a pretty lofty statement to make. What exactly is this definition of negative impact? Please elaborate, or provide sources, rather than making blanket statements of negativity.