1000mg 5-htp prior to 100mg MDMA, to "reclaim" first-time experiences??

[wynter]

I hear that if you take a 100 mg capsule every 30 mins for 5 hours before the pill, that you can have an experiences JUST like the first time, if not, better. Okay, sure I believe this, since loading up on 5-htp is like loading a petrol tank.

From other people's experiences, they say it can be done as many times as you like and will hit same as everytime you would preload with the same amount of 1000mg 5htp and 100mg - 120mg mdma.

My question is:
Doesnt this build tolerance?
Does this mean I can be a weekly user?
Does this mean I can preload on friday night & postload, and preload saturday night without any loss of effects since I am "refilling" the petrol tank with serotonin?

Reputation Comments on this post:

Inconclusive at BEST. There are better threads regarding regaining the magic. Specifically the st johns wort technique.

[enquirewithin]

There has been a lot of discussion about this and most people seem to say that the 5-HTP pre-loading lessens rather than intensifies your 'roll.'

Perhaps SWIK could try and write about it?

Trying to recapture one's first MDMA experience is like trying to regain one's virginity!

[acolon_5]

Try Piracetam. It has worked WONDERFULY for SWIM. He thought the magic was gone, but no! A few days of 1600mgs of this stuff and it is back...not to mention that for some reason, it makes the roll last LONGER.

[TMM]

Your first time is special because it's your first time. You're not going to get that back. Stop trying.

[KyleM]

Before SWIY takes large amounts of 5-HTP, he should take small doses to adapt his body to it for a week or so, otherwise taking large doses of 5-HTP can be very nauseating if one is not used to it.

And to answer SWIY's questions. Yes, this will rapidly build tolerance, much quicker than without 5-HTP. Being a weekly user with 5-HTP would not be a good idea, this may cause massive down-regulation and not allow for receptors to up-regulate if SWIY constantly takes 5-HTP. Postloading may prevent harsh comedowns, but it prevents receptors from up-regulating to original levels and SWIY will quickly lose his/her ability to roll at all. Low receptor tolerance is much harder to fix than low serotonin tolerance.

If it were SWIM, he would try it once, then not take 5-HTP or MDMA for a while. He would wait at least a few weeks or more (longer the better) before he tries taking large preloads of 5-HTP again.

[sg43]

SWIM has also noticed in a decrease in mdma effects when taking 5htp within 48 hours of mdma, it is very good for taking after or while the effects ware off to recover however.

[naatural]

that much 5-htp destroys your liver i would stear clear

[KyleM]

Originally Posted by naatural

that much 5-htp destroys your liver i would stear clear

Studies have used up to 900mg per day with no problems, SWIM believes this applies more to those with pre-existing liver conditions.

Originally Posted by sg43

SWIM has also noticed in a decrease in mdma effects when taking 5htp within 48 hours of mdma, it is very good for taking after or while the effects ware off to recover however.

SWIM has also had wonderful results from taking 1250mg in divided doses throughout the day before taking MDMA. These claims seem very anecdotal to each user. Some may not have had the roll they hoped for after preloading with 5-HTP and point the finger at 5-HTP as the reason, while others swear by it. There could be many factors involved, but SWIM doubts that simply having higher levels of 5-HTP should interfere because they (MDMA & 5-HTP) do not absorb the same way and 5-HTP should be giving the MDMA something to feed off of in essence.

[wynter]

So is it best to take the last of the 1000mg 5-htp capsule WITH the pill..

OR

Take the last capsule 3 hours BEFORE the pill

OR

Take the last capsule 48 hours BEFORE the pill?

[Bajeda]

Originally Posted by acolon_5

Try Piracetam. It has worked WONDERFULY for SWIM. He thought the magic was gone, but no! A few days of 1600mgs of this stuff and it is back...not to mention that for some reason, it makes the roll last LONGER.

Piracetam has proven awesome with amphetamines in general, and with MDMA and MDA it really has synergy. I'd have to agree with you. Mr. Panda found that the MDMA/MDA experience was intensified to varying extents once he was on a piracetam regimen and took additional amounts along with the drug, and some aspects of the quality and duration of the experience seemed to be altered as well, though its hard to qualify the Panda's perceptions.

Overall I think piracetam is something worth trying when attempting to potentiate or simply improve the MDMA experience.

For Mr. Panda, 5-HTP is something taken the day before a roll and right after the roll. He found that if he took it before he either wouldn't notice much of a change or he would get a diminished level of effects in some respects.

[wynter]

Which is better? Piracetam or 5-htp? What does piracetam actually do?

[Fantasian]

SWIF thinks piracetam dilates the blood vessals in the brain allowing for more oxygen and blood to get to it, but also it suppose to affect the receptors themselves causing them to upregulate. There is alot to piracetam, it seems like a bit of a wonder drug from what SWIF has read but he has yet to try it.

[medievil]

piracetam does indeed work

[Fantasian]

Originally Posted by medievil

piracetam does indeed work

is there an experience report of this anywhere, SWIF is still yet to find one.

[Broshious]

SWIM read a study where they gave rats 5-htp and L-Tryptophan prior to taking MDMA, and it was able to prevent any damage from occurring so even if it doesn't make you roll harder it may be worth taking.

[KyleM]

SWIM would still not rule out 5-HTP or L-Tryptophan from making SWIY roll harder. MDMA reduces tryptophan-hydroxylase so 5-HTP would be the better choice as it skips this step. There are reports that serotonin depletion is still evident years after MDMA use. Eventually SWIY will need a serotonin precursor in order to achieve the serotonin levels SWIY had for his/her first experience, unless he/she is patient enough to wait very long periods of time between MDMA sessions. Piracetam should help lower tolerance, but eventually serotonin will need to be replenished because SWIY could have no tolerance and all the receptors he/she needs to have a wonderful MDMA experience, but still have insufficient levels of serotonin to utilize all those receptors and lack of tolerance. SWIM believes that pre-loading with 5-HTP should enahance the experience if one is deficient in serotonin levels needed for rolling. It may not hurt to try piracetam and 5-HTP together.

Reputation Comments on this post:

Informative

[sockchemy]

SWIM has tried 5-HTP in many different ways before MDMA. Of course, it is nearly impossible to know what difference it made being you cannot truly A-B experiences. SWIM's feeling, however, is that it does not really enhance MDMA. SWIM has pre-loaded with a few different methods and it just doesn't seem to help. SWIM has even been suspicious if it might not hurt the effect rather than enhance it.

[Broshious]

Originally Posted by sockchemy

SWIM has tried 5-HTP in many different ways before MDMA. Of course, it is nearly impossible to know what difference it made being you cannot truly A-B experiences. SWIM's feeling, however, is that it does not really enhance MDMA. SWIM has pre-loaded with a few different methods and it just doesn't seem to help. SWIM has even been suspicious if it might not hurt the effect rather than enhance it.

The question I have is how long it takes for the 5-HTP to be converted to Serotonin. If you do it too soon then I'd think the levels would go back down, but if you wait too long then it won't have helped much. Also, if you do it for like a week before-hand then it could maybe cause some down-regulation. Does anyone have any solid information on how quickly serotonin is created and such?

[KyleM]

Originally Posted by sockchemy

SWIM has tried 5-HTP in many different ways before MDMA. Of course, it is nearly impossible to know what difference it made being you cannot truly A-B experiences. SWIM's feeling, however, is that it does not really enhance MDMA. SWIM has pre-loaded with a few different methods and it just doesn't seem to help. SWIM has even been suspicious if it might not hurt the effect rather than enhance it.

What was the largest amount SWIY took? Remember that a significant amount will be converted to serotonin in the bloodstream, which cannot cross the blood-brain barrier. So taking a few small doses will probably not be sufficient enough to replenish serotonin if it is significantly depleted in areas.

Originally Posted by Broshious

The question I have is how long it takes for the 5-HTP to be converted to Serotonin. If you do it too soon then I'd think the levels would go back down, but if you wait too long then it won't have helped much. Also, if you do it for like a week before-hand then it could maybe cause some down-regulation. Does anyone have any solid information on how quickly serotonin is created and such?

The newly created serotonin is stored in vesicles until it is needed so next time SWIM takes MDMA, there will be a larger supply for MDMA to release from the vesicles. It can cause downregulation itself and increase the down-regulation caused by serotonin release. 5-HTP will allow more "fuel" for rolling, but will accelerate receptor-related tolerance.

As for the time it takes for 5-HTP to be converted, that really depends. There are other vitamins and such involved in the conversion process. Also, as SWIM previously stated, much will convert in the bloodstream if it is decarboxylated before it crosses the blood-brain barrier, so it will take longer to have elevated serotonin levels in the brain. But 5-HTP does have a half-life of about an hour and a half, so most will be gone after 5-6 hours or so.

[hoodabudda]

Originally Posted by enquirewithin

Trying to recapture one's first MDMA experience is like trying to regain one's virginity!

chicks can get there hymens replaced lol

[sockchemy]

SWIM has tried 50MG and 100 mg 1 hour before MDMA. SWIM has tried loading with 50 MG of 5 HTP every 2 hours for 8 hours before MDMA. SWIM has never tried a dose as large as 1000 MG as was described in the original thread. Like SWIM said, you can't truly A-B experiences, but SWIM didn't perceive any gain from the 5-HTP. Of course, SWIM is willing to try any recommendations as SWIM really wants it to work!

[Beta]

My cat observed that, amongst legal substances, piracetam (with choline), sam-e and acid alpha lipoic (take after the peak) are the most effective way to enhance mdma experience.

Reputation Comments on this post:

thanks for the tips ;)

[titanic]

Originally Posted by marcan

My cat observed that, amongst legal substances, piracetam (with choline), sam-e, levitra and acid alpha lipoic (take after the peak) are the most effective way to enhance mdma experience.

SWIM finds this topic very interesting and was wondering what kind of a pill piracetam was...

SWIm was wondering is this a over the couter drug that can be easily available..

[Beta]

Originally Posted by titanic

SWIM finds this topic very interesting and was wondering what kind of a pill piracetam was...

SWIm was wondering is this a over the couter drug that can be easily available..

Here it's cheap and easily available. Normally, you should have a prescription but I never need it.

[wynter]

How much piracetam in mg should Mr.Cool take before popping? How and when?