Phenibut sucks

Phenibut was prised as a chemical GHB related, relexant, I tried this stuff first 2 g after 40 min 2g again and I felt nothing with exception a huge desire to sleep.


fuck this stuff is not the money worth.

[hitman278]

Guest. Fill me in with what Phenibut? I've never heard of it. I am guessing that it is some kind of G?


Take care.

[Alfa]

Phenibut (beta-phenyl-gamma-aminobutyric acid) was developed in Russia in the 1960's and is used for its anxiety-reducing effect as well as for its nootropic effect. Phenibut iiis structurally similar to the inhibitory neurotransmitter GABA, but it more effectively crosses the blood-brain barrier.
In Russia phenibut is used to treat post-traumic stress disorder, stuttering, and insomnia.


Phenibut (beta-phenyl-gamma-aminobutyric acid HCl) is a neuropsychotropicdrug that was discovered and introduced into clinical practice in Russiain the 1960s. It has anxiolytic and nootropic (cognition enhancing) effects. It acts as a GABA-mimetic, primarily at GABA(B) and, to some extent, at GABA(A) receptors. It also stimulates dopamine receptors and antagonizes beta-phenethylamine (PEA), a putative endogenous anxiogenic.The psychopharmacological activity of phenibut is similar to that of baclofen, a p-Cl-derivative of phenibut. This article reviews the structure-activity relationship of phenibut and its derivatives. Emphasis is placed on the importance of the position of the phenyl ring, the role of the carboxyl group, and the activity of optical isomers. Comparison of phenibut with piracetam and diazepam reveals similarities and differences in their pharmacological and clinical effects. Phenibut is widely used in Russia to relieve tension, anxiety, and fear, to improve sleep inpsychosomatic or neurotic patients; as well as a pre- or post-operative medication. It is also used in the therapy of disorders characterized by asthenia and depression, as well as in post-traumatic stress, stuttering and vestibular disorders.

[Francois]

Originally Posted by Alfa

Phenibut (beta-phenyl-gamma-aminobutyric acid) was developed in Russia in the 1960's and is used for its anxiety-reducing effect as well as for its nootropic effect.

Hi all, sorry, I am new here and may be repeating the obvious or the oft-posted.

Just a quick thought: I would not advise experimenting with high doses of any psychotrope developped in the Soviet Union unless you have a soviet doctor at hand (I do: I live in Kyiv, Ukraine)

The reason is that double-blind, placebo-controlled studies on pharmacology and toxicity were done (and still are done) in a rather creative way, if at all.

Remember what psychiatry was used for here until 1989...

Now, I just was prescribed Phenibut 2,5 g. tid for anxiety disorder in combination with Novo-Passit (and if someone can tell me what THAT is, I would be grateful...) So far, so good, obvious skeletal muscle relaxation, no drowsiness, none of the typical benzodiazepine depressive effects.

Enjoy!

[Abrad]

Originally Posted by Francois

Now, I just was prescribed Phenibut 2,5 g. tid for anxiety disorder in combination with Novo-Passit (and if someone can tell me what THAT is, I would be grateful...)

Here is some information, it seems to be some kind of herbal remedy.

NOVO-PASSIT®
oral solution



Marketing Authorization Holder and Manufacturer:
IVAX Pharmaceuticals s.r.o.
Opava-Komárov
Czech Republic



Composition:
Active Ingredient:
Herbarum extractum. for Passit fluidum (Hyperici herbs, Passiflorae herbs, Valerianae radix, Crataegi folium cum flore, Lupuli flos, Melissae herbs, Sambuci flos ) 7,75 g, Guaifenesinum 4,0 g in 100 ml.
Excipients:
Saccharine, Sodium Benzoane, Sodium cyclamate, Propyleneglycol, Invertosa, Ethanol 96%, Maltodextrin, Xanthene gum, Dihydrate of sodium citrate, Orange aroma, Purified water. Sodium content: 0,11 g in 100 ml

Indication group:
Sedative, anxiolytics.

Characteristics:
The product is a combination of extracts of herbs with sedative effect and guaiphenesine. Guaiphenesine removes fear and psychical tension and relieves skeletal (striated) muscle.

[Hover]

Originally Posted by Abrad

The product is a combination of extracts of herbs with sedative effect and guaiphenesine. Guaiphenesine removes fear and psychical tension and relieves skeletal (striated) muscle.

Guaifenesin is a very common expectorant drug here. Swim didn't know it had other properties.

[sunra]

My one experience of phenibut was taking 6 grams over the course of a night. I did feel some mood elivation and I felt able to concentrate and interact socially, justifying its nootropic tag.

However the next day when I woke up I felt nauseous each time I attempted to move, this lasted all day. I could not even read because my eyes had difficulty focusing.

While taking 6 grams was obviously with hindsight stupid, other people have used phenibut as a proper nootropic, i.e taking small amounts over a period of weeks.I have read reports of people then coming off phenibut and suffering withdrawl symptoms similar to the hangover that I experienced. My hangover lasted a day the withdrawl symptoms can last the best part of a week.

[Cleaver]

Phenibut is a great anti-anxiety chemical. It's recreational usage is relatively non-existent though. While playing around with Phenibut, I could consume incredible amounts of caffeine and had almost no jittery side effects. Where as before, a single cup of coffee would make my left hand shake uncontrollably.


I am convinced it's anti-anxiety property is synergistic with GBL. So, if you are using GBL frequently, you can use Phenibut late at night to kill the dopamine rebound effect. Very interesting combination.

[blackwolf]

^^^^I feel the same way. If you are wanting to get fux0r3d it wont
happen....... but if used for antianxiety, and not daily, I have found it very
usefull. I take 10-15mg on fmethamphetamine hcl (desoxyn) daily, for
adhd, and found that during times of high stress that phenibut would
calm any anxiety and help me focus on th etask at hand. I also have
found no side effects from mixing the desoxyn with the phenibut.

[unico_walker]

Some will disagree with me here,but you should not try to get fuxxored on GHB or any of its analogs.

Its a waste and a terrible high,use it in mood elevating and anti-anxiety doses.



Phenibut isn't bad,its great for the post g shakes.

One interesting thing I have noticed is that even taking 12 grams of
Phenibut(I did this to confirm something) I was anxiety free for 4 days.

I found I cannot get fuxxored on phenibut,its odd like it has a set
rate of metabolism that it won't exceed,high doses simply last longer.

Hopefully this will keep people from passing out in public and getting this thing in the spotlight.

[Cleaver]

Yeah, I think Phenibut is a whole new generation of anti-hypertension drugs. Powerful drug with no apparent side effects once you have built up a tolerance. Like ANY anti-hypertension/depressant it has some withdrawl effects. But, it doesn't tickle any pleasure receptors. I hope it stays around for a while.


I wonder what a combo like Phenibut + Neurontin would feel like?

[blackwolf]

I dont know but I am getting a new bottle of phenibut tomorrow......YAY. I
dont have any Neurontin though....so I wont be able to experiment for
you.

I would like to see how phenibut combines with a mild dose of
psychedelics. Maybe swim will have a go at it and let me know.

[Richard_smoker]

in my opinion, phenibut doesn't do anything...


and supposedly, if it DOES do anything, you have to wait FOREVER (like 2 hours) and all it does is make you really sleepy for the next day.


what!?? This is how my nights/mornings are anyways... no buzz, no euphoria, up late, and really sleepy the next day.


We need something WAY better than THIS guys! way better.


Even if it isn't for human consumption.

[snapper]

It really helps with withdrawals from GHB and friends, as well as
dopamine rebound effects. If you feel yourself trapped in that loop,
Phenibut really takes the anxiety away and helps with some of the other
withdrawal effects. Good to have handy just in case.

Snapper

[tinogsx]

The best thing about Phenibut is the "afterglow" the next morning.

[estel]

I have extensive experiance with phenibut ( i have used it 50+ times) and i find that is it good for anxiety but it's no 'high'.

The only time i've seen it do anything drastic is when two friends of mine each took ~ 7g for there first time (foolish i know) they acted like they where drunk and puked up loads. Almost took them to hospitol.

They also passed out a bit like you would from G. So a little warning for everyone out there this stuff does have quite a kick to it in higher doses and it lasts ages.

Estel

[Nagognog2]

I can identify 3 of these in the Novo-Passit: St. John's Wort. Passionflower (harmaline and related alkaloids). Valerian.

Sounds like a soothing blend that would, due to the St. John's Wort, take a few weeks to reach full effect.