MDMA = parkinson cure

[c_lectric]

In a Dissertation from the year 2002 at german university Tübingen an experiment was performed which lead to the conclusion, that MDMA can cure parkinson.

0,5 mg/kg Haloperidol, injected, leads to a distinctive catalepsy.

Wikipedia:
(Catalepsy is a condition characterized by muscular rigidity, fixity of posture and decreased sensitivity to pain.)

doses of 1, 2.5 and 5 mg/kg MDMA were injected into the mice.

1 mg/kg showed a 57% reduction in catalepsy effects
2.5 mg/kg 88,7% reduction.
5 mg/kg 97,7% reduction

in several tests.


this lead to the conclusion that MDMA (yes the KILLERDRUG ECSTASY) can cure Parkinson!



source: (german)
h**p://deposit.ddb.de/cgi-bin/dokserv?idn=965404625&dok_var=d1&dok_ext=pdf&filen ame=965404625.pdf

there is also a nice synthesis to mdma used in this dissertation from Piperonal using Fe(III)Cl to produce the piperonylacetone. tell me if you are interested, then i will do a translation maybe.

[Pondlife]

I saw a BBC "Horizon" documentary about a similar thing back in 2001. In this documentary Tim Lawrence, who is a parkinson's sufferer showed the positive effects of MDMA. Here's a link to the summary:

http://news.bbc.co.uk/1/hi/health/1169980.stm

Maybe it's available on youtube or similar, but I've not managed to find it.

[c_lectric]

so this is not news.... but why isnt E allowed then
lets cure all the parkinson sufferers.


another parkinson news:

The researchers also found that those who smoked and those who were alcoholics were less likely to have Parkinson's.

http://news.bbc.co.uk/2/hi/health/736017.stm

this is hillarious xD

drink, smoke and take E to not get/cure parkinson.

[spiderpig]

Originally Posted by c_lectric

.... but why isnt E allowed then
lets cure all the parkinson sufferers

Swim has not ever come across much death related information before the dea's ban on mdma, after that it seems all hell began to break loose. E used to be sold in bars for god's sake, now swim is afraid to give his friend a pill for fear of harmful contents.

[FrankenChrist]

If you could only find a cure for serotonin and dopamine depletion first.

[c_lectric]

Originally Posted by FrankenChrist

If you could only find a cure for serotonin and dopamine depletion first.

i could help you there


after using E and before going to bed take 500mg L-Tryptophan or 50-150mg 5-hydroxytryptophan (both amino acids).

they will help your brain cells produce new Serotonin, thus lowering the side effects of mdma.

also take Vitamine B6 and B3 supplements. they are used as coenzymes in the biosynthesis of serotonin. magnesium supplements could help also.


5-HT (~100 mg) + Vitamine B3/B6 + Magnesium

[FrankenChrist]

Originally Posted by c_lectric

i could help you there


after using E and before going to bed take 500mg L-Tryptophan or 50-150mg 5-hydroxytryptophan (both amino acids).

they will help your brain cells produce new Serotonin, thus lowering the side effects of mdma.

also take Vitamine B6 and B3 supplements. they are used as coenzymes in the biosynthesis of serotonin. magnesium supplements could help also.


5-HT (~100 mg) + Vitamine B3/B6 + Magnesium

Please. You don't have to tell me. Besides, you don't sound like a neurologist or biochemist for that matter. It's not that simple. But thanks for trying to help.

Something tells me that you can't keep doing this time after time if you have Parkinson's. Even with supplements it takes a certain period of time before your neurotransmitter levels are back to normal.

[Evil GIR]

MDMA may not be the drug that cures the disease but I beleive it could be a tool to create an analog that is more specific. As for depletions of serotonin and dopamine, i guess 5-HTP and L-Tyrosine supplements could be helpfull.

Reputation Comments on this post:

:D

[Evil GIR]

Yeah they both precursors and can be found at heath food stores.

[yozman]

just had a look at my protein powder bag and there is 405mg of tryptophan per serving. no htp but still, good to know im getting plenty of tp. hav a multi and a shake after a night clubbing

[Jatelka]

For any flamingo who may be interested:

Here are some relevant archive articles:

http://www.drugs-forum.com/forum/loc...=3088&catid=36
http://www.drugs-forum.com/forum/loc...=3089&catid=36

[c_lectric]

Originally Posted by Jatelka

For any flamingo who may be interested:

Here are some relevant archive articles:

http://www.drugs-forum.com/forum/loc...=3088&catid=36
http://www.drugs-forum.com/forum/loc...=3089&catid=36

the first one is a small version of the document i refered to (which is in german). has exactly the same results.

[Nacumen]

Take MDMA daily to forgo Parkinson's, only to start down the path towards Alzheimer's? I'll stick with Parkinson's.

[Evil GIR]

Wouldn't that depend on the dosage ?

I wonder what the minimal dosage would be for it to have a positive effect on parkinson's and less of a negative effect on the brain.

[Earlocybin]

Hehe, and not too many years ago they were saying MDMA CAUSED Parkinson's.

[Eurorider1]

I member reading a story on Parkinson's and a man who used xtc illegally to help him be allowed to use his arms and legs well control them it does actually work. I did a lil testing myself with family who has a forum of parkinson's and it does help them to focus more and have more control of legiments..

[FrankenChrist]

Originally Posted by Eurorider1

I member reading a story on Parkinson's and a man who used xtc illegally to help him be allowed to use his arms and legs well control them it does actually work. I did a lil testing myself with family who has a forum of parkinson's and it does help them to focus more and have more control of legiments..

I'm not judging you or anything, but just to clear things up I'd like to ask if you gave someone MDMA with that purpose, and if it was with their consent.

[imyourlittlebare]

this is ridiculous.
1. lack of dopamine causes parkinsons due to destruction of certain brain areas (basal ganglia) involved in movement. serotonin helps but isnt going to cure. mdma wont help. its a stimulant which is great and thats why it HELPS. but not preferable. the best available treatments and treatments to come are l dopa, deep tissue stimulation, brain lesioning, using stem cells to recreate damaged brain areas and using an electrode to stimulate for months the areas effects.

2. i believe someone confused mdma causing parkinsons and mptp. mppp is a stimulant similar to meth and ex. however, it can EASILY be made wrong. its very hard to made mppp. so the result is mptp which DOES cause parkinsons. it was legal for a short time and caused a wave of young people in 20s and 30s to get parkinsons. once the damage is done by the drug it is irreversable and will continue to damage itself without proper treatment.

Reputation Comments on this post:

nice post - tim

[Eurorider1]

swim was contacted by a family member who has a disease called ataxia it affects your nervous system and the nerotransmitter signals down your spine.. they have been have problems with speech, also movements of ligaments such as arms, legs and so forth.. they asked me bout the drug of choice because they knew i did it.. they havent ever used drugs in their life time and only heard stories bout ecstasy. swim said then take half and see what it does after waiting for about 30 mins they started to feel emotionally pain free and were able to move their arms and legs and focus on their talking with out mental stress.. They because of this disease has very hard trouble doing multi things at once.. he was able to walk and talk and then write on paper and talk at the same time... I saw it as being a big thing because it allow'd swim to see a person he loves finally happy.

[medievil]

hmm, SWIM beleives that DMT in daily low doses might be the cure... (anecdotaaly DMT seems to have the same positive effect on movement as MDMA

but its only an anecdotal report, so i dont know, i do think its better to take DMT daily as it does not cause tolerance

[eltimmy]

Not a cure, a reduction in symptoms.

That amphetamines will alleviate dopaminergic deficits (temporarily) is well known.