Drug info - Flexeril (Cyclobenzaprine)

[Colby]

Just wondering what would you all rate Flexeril. My buddy has quite a few and says they are a lot like somas. I have taken somas before and gotten straight shit faced, are these things any good compared to somas?


Also, how many would I need to take to be on a good level? I have heard they are not as strong as somas, but are still good.

[OneDiaDem]

I like em, they are weaker than soma's tho. It all depends on your tolerance. Try one and go from there.</font>

[xMeTaL HeAdx]

10 mg's to start out. I like em a lot, on a scale of 1-10 id give em a 7 or 8

[Colby]

I am going to be getting two 10MG Flexeril and 1 Loratab, is this a good mix? Also be smoking a few blunts

[Colby]

Just to let ya'll know, mixing those two is all good, and its pretty bomb too

[Herbal Remedy]

hey, i was on darvocet for an neck injury for a week or so but i asked my doctor for something a lil less strong cuz i was noticing i was having too much fun with them, then they started not doing much for me at all and i was popping them like crazy,and when i wasnt on them i felt like shit (pain and depression for some reason). i asked for some muscle relaxers that i could take in the morning and at nights cuz thats when my neck pain was the worse. he gave me these cyclobenzaprine muscle relaxers and i took one last night and noticed they made me very drowsy, pretty sedated... i was wondering anyone had any info on these pills, im not even sure what classification they fall under so im sorry if this is the wrong forum. also just wondering if i can have some fun with them in any way, theyre 10mg tablets, kinda small... any replies are really appreciated...

[BA]

Flexeril

Category
Skeletal muscle relaxant

Description
Cyclobenzaprine (sye-kloe-BEN-za-preen) is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects

[Benzhead]

Well, it's not a benzo..it doesn't have the typical diazepine + benzene ring common to all benzos.


However, Cyclobenzaprine ismore chemically akin to common tricylic anti-depressants(Imipramine, Amitriptyline, etc.) with a novel analgesic effect.


There arevery fewexperience reports at Erowid.org


As far as 'having fun with them' is concerned, check out Erowid and please watch your dosing(s). Nosense becoming a statistic when all you had in mind was a little pleasure.


(OD info. is available at RxList.com and many other pharm sites)

[Herbal Remedy]

Hey thanks for the quick replies! sorry, i usualy always refer to erowid but for some reason i keep forgetting about those drop down bars (pharmacueticals being one)... thanks for pointing me in the right direction.


As for the "having fun" part, im definantly gonna stay away from taking more than the recommended does since i went through some hell finding out what can go wrong with that while on the darvocets (i really lost it, they made me feel soo good but when i wasnt on them i felt very low and so i didnt want to refill my script for fear things would only get worse).


I'll probably just end up throwing back a few shots along withmy nightlypill to see if theres any kinda comfy mix i could fall back on during the rough nights of my drug court program... thanks again!

[Psilocybe S.]

I dont like flexeril too much. It's too week for me. I tried using it for meth withdrawls, and it was okay for that. It made me relax a little, and with some pot, I was able to go to sleep. But over all, they're too weak and unsatisfying for my taste.

Reputation Comments on this post:

don't incriminate yourself!

[tweakerfrommars]

Nice for a night of relaxation, or to hold me over from another drug craving.

[Zandorf]

SWIM's roomate was prescribed ten 10mg flexeril for his lower back problem last december.



SWIM and his roomate each insufflated one pill, no special
modifications to the dorm room environment were made. it was maybe 5pm.



Within 20 minutes a drowsy haze settled over each of them. SWIM began
to nod in and out of consciousness, he would intend to do
something(such as pick up the remote and change the channel), nod out,
dream that he'd done it and wake up in utter confusion.



At approximately 8pm some friends called the room, SWIM's roomate
answered groggily and promtly handed the phone to SWIM, who also talked
in a detached manner. The caller must have thought he was calling an
opium den.



Soon after both drifted off to sleep, SWIM awoke feeling unrefreshed and was tired throughout most of the following day.

[Interzone]

Flexeril, or it's generic name Cyclobenzaprine HCL is not as good as SOMA in my opinion. SOMA has a more mellow, happy type of relaxation to it, while Flexeril, to the intolerant user is extremely hard-hitting in that it knocks you on your ass and puts you into a shitty sleep. If you are used to muscle relaxers however it usually does nothing, and has to be taken at least 2-3 days in a row, 3-4 times a day to get a cumulative effect much like SSRI's. I would stick to the best: SOMA, or it's generic: Carisoprodol.

[peggs16]

Some people say that flexiril gets you high. I have 90 10mg pills........whats the best way to get high from them?

[magicmaster141]

What is it? Is that a muscle relaxer? I know I've heard of it before, might be the same thing I took a few times but I don't remember. If it is what I took I wouldn't try getting high off it I didn't enjoy it, but I'm not sure if it is. Sorry I can't be of more help

[BA]

SIDE EFFECTS
Incidence of most common adverse reactions in the 2 double-blind‡, placebo-controlled 5 mg studies (incidence of &gt; 3% on FLEXERIL 5 mg):


FLEXERIL 5 mg N=464
FLEXERIL 10 mg N=249
Placebo N=469

Drowsiness
29%
38%
10%

Dry Mouth
21%
32%
7%

Fatigue
6%
6%
3%

Headache
5%
5%
8%



Adverse reactions which were reported in 1% to 3% of the patients were: abdominal pain, acid regurgitation, constipation, diarrhea, dizziness, nausea, irritability, mental acuity decreased, nervousness, upper respiratory infection, and pharyngitis.

The following list of adverse reactions is based on the experience in 473 patients treated with FLEXERIL 10 mg in additional controlled clinical studies, 7607 patients in the post-marketing surveillance program, and reports received since the drug was marketed. The overall incidence of adverse reactions among patients in the surveillance program was less than the incidence in the controlled clinical studies.

The adverse reactions reported most frequently with FLEXERIL were drowsiness, dry mouth and dizziness. The incidence of these common adverse reactions was lower in the surveillance program than in the controlled clinical studies:

‡ Note: FLEXERIL 10 mg data are from one clinical trial. FLEXERIL 5 mg and placebo data are from two studies.


Clinical Studies With FLEXERIL 10 mg
Surveillance Program With FLEXERIL 10 mg

Drowsiness
39%
16%

Dry Mouth
27%
7%

Dizziness
11%
3%


Among the less frequent adverse reactions, there was no appreciable difference in incidence in controlled clinical studies or in the surveillance program. Adverse reactions which were reported in 1% to 3% of the patients were: fatigue/tiredness, asthenia, nausea, constipation, dyspepsia, unpleasant taste, blurred vision, headache, nervousness, and confusion.

The following adverse reactions have been reported in post-marketing experience or with an incidence of less than 1% of patients in clinical trials with the 10 mg tablet:

Body as a Whole: Syncope; malaise.

Cardiovascular: Tachycardia; arrhythmia; vasodilatation; palpitation; hypotension.

Digestive: Vomiting; anorexia; diarrhea; gastrointestinal pain; gastritis; thirst; flatulence; edema of the tongue; abnormal liver function and rare reports of hepatitis, jaundice and cholestasis.

Hypersensitivity: Anaphylaxis; angioedema; pruritus; facial edema; urticaria; rash.

Musculoskeletal: Local weakness.

Nervous System and Psychiatric: Seizures, ataxia; vertigo; dysarthria; tremors; hypertonia; convulsions; muscle twitching; disorientation; insomnia; depressedmood; abnormal sensations; anxiety; agitation; psychosis, abnormal thinking and dreaming; hallucinations; excitement; paresthesia; diplopia.

Skin: Sweating.

Special Senses: Ageusia; tinnitus.

Urogenital: Urinary frequency and/or retention.

Causal Relationship Unknown

Other reactions, reported rarely for FLEXERIL under circumstances where a causal relationship could not be established or reported for other tricyclic drugs, are listed to serve as alerting information to physicians:

Body as a whole: Chest pain; edema.

Cardiovascular: Hypertension; myocardial infarction; heart block; stroke.

Digestive: Paralytic ileus, tongue discoloration; stomatitis; parotid swelling.

Endocrine: Inappropriate ADH syndrome.

Hematic and Lymphatic: Purpura; bone marrow depression; leukopenia; eosinophilia; thrombocytopenia.

Metabolic, Nutritional and Immune: Elevation and lowering of blood sugar levels; weight gain or loss.

Musculoskeletal: Myalgia.

Nervous System and Psychiatric: Decreased or increased libido; abnormal gait; delusions; aggressive behavior; paranoia; peripheral neuropathy; Bell’s palsy; alteration in EEG patterns; extrapyramidal symptoms.

Respiratory: Dyspnea.

Skin: Photosensitization; alopecia.

Urogenital: Impaired urination; dilatation of urinary tract; impotence; testicular swelling; gynecomastia; breast enlargement; galactorrhea.

DRUG ABUSE AND DEPENDENCE

Pharmacologic similarities among the tricyclic drugs require that certain withdrawal symptoms be considered when FLEXERIL is administered, even though they have not been reported to occur with this drug. Abrupt cessation of treatment after prolonged administration rarely may produce nausea, headache, and malaise. These are not indicative of addiction.

DRUG INTERACTIONS
FLEXERIL may have life-threatening interactions with MAO inhibitors. (See CONTRAINDICATIONS.)

FLEXERIL may enhance the effects of alcohol, barbiturates, and other CNS depressants.

Tricyclic antidepressants may block the antihypertensive action of guanethidine and similarly acting compounds.

Tricyclic antidepressants may enhance the seizure risk in patients taking tramadol.

[Benzeneringz]

Cyclobenzaprine (Flexeril) is, strangely enough, a tricyclic drug as well as a muscle relaxant. SWIM has had a generous amount of experience with cyclobenzaprine, albeit with lower doses save a single high-dose experience. Here's my 2 cents:

-- Flexeril does indeed "feel like something". Some muscle relaxants, such as metaxalone (Sklaxin) have very little to no "feel-drug effect", even in extremely high doses*. SWIM remembers a specific incident with a friend where SWIM and her had each taken 20 mgs cyclobenzaprine and an hour later SWIM declares out-loud "I definatly feel something, I can't put my finger on it but this is definatly cyclobenzaprine-induced". The friend didn't feel a thing and never has on the drug.

--When one goes 72 hours without eating a single bite of food, the effects of drugs taken orally are multiplied by at least 5. SWIM knows because has done just that more that 75 times (but thats another story for another day). Anyway, one night, after 75 hours without eating SWIM sublingually took 10 milligrams of cyclobenzaprine (it burns the tongue.. baad). The effects were extremely pronounced; muscle tone was greatly reduced and my body became relaxed. The tension was sucked out. There was little disruption of cognitive skills, marked sedation, and minor coordination difficulties. The effects would definatly be labled as pleasant; not euphoric like hydrocodone or amphetamine, but pleasant like Xanax or Soma. This means that, with sufficient doses, cyclobenzaprine is rewarding and/or posesses abuse potential.
--At theraputic doses, cyclobenzaprine is not rewarding but it is indeed theraputic in painful muscle conditions.

Hope this helps a little.

[DrMuffy]

SWIdr has had several experiences with Flexeril, and it does definatly help relax your muscles (of course). Alone it doesnt produce much of anything (euphoria wise, that is) but it can really add to opiates and benzos. So in that case SWIY could combine them and it would probably produce SWIY's desired effects. Of course mixing CNS deppresants can be dangerous, so be extremely careful if you choose to do so!

Reputation Comments on this post:

Good warning & advice!

[peggs16]

Ok, i went through vike and heroine withdrawl bad.......ended up eating maybe 15-20 10mg of flexril. It did shit to me. I don't know why. on another occassion i had like 15 more (no withdrawal)just to relax me and it did shit. Should i snort them............what should i do..........................thanks

[OiledMandible]

Hmmmm.....A few always worked for me. Just a stab in the dark,
but maybe you need to take them over and over before they begin to work
(think allergy medication).



Flexeril is cyclobenzoprene (sp?), correct?

[Mike177]

Flexeril is Cyclobenzaprine, an Un-Scheduled muscle relaxant.

[GForce]

SWIM recently pulled his trapezius muscle and was prescribed 10mg tablets of cyclobenzaprine. His doctor warned him about combining the medication with clonazepam as he has been prescribed clonazepam for a while now. Conveniently enough there is a pharmacy in his University's health service and he was able to fill the prescription before he left. He had taken 2mg of clonazepam earlier in the day (maybe 2 hours prior) which constitutes nothing more than a therapeutic dose for him so he figured the cyclobenzaprine wouldn't be that intense in combination. He took 20mg before he left health service and drove home (about 5 minutes away) no problem. From the time he took the medication to the time he pulled up on his driveway at least 20 minutes had elapsed, but not much more. He got out of the car feeling fine and began walking down his driveway only to realize his balance was severely impaired. He fell flat on his face and, ironically, ended up injuring his knee worse, pain-wise, than his neck. SWIM didn't suffer any serious damage to his knee, just a lot of scrapes and blood, so he cleaned it and the pain was gone pretty quickly.

After this he sat in his room listening to music and realizing how intense the synergy between clonazepam and cyclobenzaprine had become. He experienced medium intensity closed eye visuals, a euphoria from relaxation, and enjoyed music more than normally. The combination eventually caught up with SWIM and made him extremely tired so he had to take a 3-4 hour nap. He woke up pretty much sober and without a problem.

SWIM knows that people differ on opinion regarding the recreational value of cyclobenzaprine and other skeletal muscle relaxants, but he had a great time on it. In fact he isn't taking it regularly because he's afraid it will mess him up too much to do his work, and his neck is a lot better now. If SWIY has the opportunity to combine a benzo with cyclobenzaprine SWIM highly recommends it. SWIM's drug tolerance is usually abnormally high, even to new medication, so had the meds been taken without the other he wouldn't feel much more than a therapeutic effect. However the combination seems to be quite potent so exercise caution if SWIY decides to combine the two.

[Politicalchalk]

Swim's heard that cyclobenzaprine (When you take it's, it's called "Cycling" tehehehe), it either works with you or it doesn't. Personally Swim's cat had taken up to 50mg with only being sleepy, and dry mouth (anti-cholinergic action, methinks). Never ran an assay with a benzo, though, so I can't say as to the synergy. Some people just love it. Clonazepam and many other benzos already act as a muscle relaxant, so there might be extra-additive effect.

Strange though, Swim's never, ever gotten the effects some others describe, at much lower doses, too. Swim has always found this confusing, as he'll generally be able to at least relate to what others psychopharmacologically describe. not this though...

[BuffaloBoobs]

This other swim just had his first cyclobenzaprine experience today.

A quick fact about swim: whenever he scores *anything* he feels the need to give it a try, as soon as possible (if at all possible).

Swim is quite experienced with carisoprodol and always had a fun, relaxing time. Swim took one 10mg cyclobenzaprine very early into the work day.

Wow.

Maybe it was just a simple underestimating of the drug, but swim became *too* relaxed and had to leave work early. It was a good thing that swim had a swell excuse--dancing and fucking the whole night before.

OK, that was a shitty excuse, but swim was free to go and almost passed out while watching Kentucky Fried Movie.

Swim plans on saving the rest for a certain music festival next week. He reckons these cyclobenzaprines will work wonders in helping swim sleep after a long, hot day of dancing and tripping/rolling/etc.

[Politicalchalk]

Festies! Whoooooooo!