Dose - How many Yopo to be orally active?

[tayo]

I know what you're thinking about the thread title, "Yopo's not orally active!" ....but with no Syrian Rue in the picture...

5-meo-dmt can be a minor MAOI itself, does anyone have an idea of how many seeds it would take to make Yopo orally active? ... I imagine it is quite a few, probably around 15-20 for inhibition and effects. Any ideas?

Does anyone know at how many mg of 5-meo-dmt an MAOI effect takes hold?

[Hyperspaceblastoff]

u dont wana take yopo orally cuz it contains bufotoxin
yopo orally=no no

[BackToBasics]

Originally Posted by Hyperspaceblastoff

u dont wana take yopo orally cuz it contains bufotoxin
yopo orally=no no

It would contain said toxin when you snort it as well would'nt it? That doesn't seem to do much harm..

[tayo]

Well actually, when taken with syrian rue Jimmy enjoyed it.

[Hyperspaceblastoff]

weirdo....

[Hyperspaceblastoff]

well i think bufotoxin is much more potent with an maoi and orally

[Anadenanthera]

Originally Posted by Hyperspaceblastoff

well i think bufotoxin is much more potent with an maoi and orally

Bufotenine is active orally at 100 mg and up. But in the stomach it gets converted to bufotenine hydrochloride, which is only pleasant at very low doses. At moderate doses it causes nausea and a whole host of other unpleasant effects.

You really want to use calcium bufotenate, not bufotenine hydrochloride. It can be made by reacting wet calcium hydroxide with any form of bufotenine. But if you ingest it orally, it gets converted back to bufotenine hydrochloride. The only way to really enjoy bufotenine is via sublingual, intranasal, or by vaporization.

Now about all the stuff you heard about bufotenine being toxic. Only certain forms are toxic. Mostly the water soluble acidic forms are (like bufotenine hydrochloride...yuck!!!) Calcium bufotenate is not toxic. Calcium bufotenate is a very pleasant experience. Its more hallucinogenic that DMT and 5-MeO-DMT. Its effects are very different from other forms of bufotenine. A strong hallucinogenic dose produces no side effects.

When I was in Brazil and took part in a medical study on the effects of bufotenine, I experience bufotenine hydrochloride, and then the natural form from a water based extract of the beans, and then free-base bufotenine, and lastly calcium bufotenate. All tests were done via vaporization using some sort of fancy vaporizer. All tests used approximately 10 mg of each compound. Bufotenine hydrochloride made me feel a little euphoria, but the entire time I felt nausea, tension in my throat, tension in my body, and got a headache. The natural one made me nauseated too, but not as bad, I felt a little tension in my body, but it was a little hallucinogenic. Not that bad actually. Free-base bufotenine was pretty good. I didn't get nauseated from it at all, I got strong visuals, but I felt a little tension in my body. Calcium bufotenate was GREAT! Way better than anything else I ever tried. Tons of visuals, more than I ever got from anything else, even DMT. I was hearing music and voices in my mind, seeing landscapes, faces, all sorts of stuff. I was blown away. At the same time, I felt relaxed and at ease with it. There was none of that nervousness felt from DMT. Also there were no side effects at all, except the first minute of it my stomach felt a little uneasy, but that passed completely within a minute. The peak was AMAZING and lasted a good 10 minutes. As with all the others, the over effects lasted 2 hours. It was administered to me at 10 mg for 5 days in a row to test for tolerance and signs of toxicity. I experienced no tolerance at all and the reports showed no signs of toxicity. All 5 trips were very enjoyable. After that they began testing it via insufflation, and I didn't want to take part in that part of the study so I stopped at that point. I'm not into putting things in my nose.