Combinations - Zyprexa and MDMA?

[richiedog]

Ive read through many of the threads posted and most say not to mix anti-depressants and MDMA.
Zyprexa is an anti-phycotic, and im pretty sure its an absolute death sentence (slightly over eggagerated)
I need to know this to show a friend who is seriously thnkning about taking X while on Zyprexa. Im really worried because ive been googling and there isnt that much info, but the info i can find suggests strongly against it.
Hopefully your wise minds will have some answers.
And also do you know if Zyprexa is a MAO inhibitor?
Need some answers,
Many thanks

[Jatelka]

Zyprexa (Olanzipine) is an atypical anti-psychotic. As well as effects at dopamine receptors it also has effects at serotonin receptors (specifically it has a blocking effect at the 5HT-2A receptor).

Mecause of it's effects at serotonin receptors the effect of MDMA is likely to be severely attenuated (if any effect is felt at all)

No idea re MAOI, sorry

[richiedog]

SO would the main concern then, be that because of zyprexa the effects are less, that one may take more, and there is more of a chancce of overdoes?