Contribution of CY3PA4, CYP2B6 and CYP2C9 Isoforms to n-Demethylation of Ketamine in Human Liver Microsomes (Hijazi and Boulieu, 2002)

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Contribution of CY3PA4, CYP2B6 and CYP2C9 Isoforms to n-Demethylation of Ketamine in Human Liver Microsomes (Hijazi and Boulieu, 2002)

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20-06-2007, 20:59

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Contribution of CY3PA4, CYP2B6 and CYP2C9 Isoforms to n-Demethylation of Ketamine in Human Liver Microsomes (Hijazi and Boulieu, 2002)

A new entry has been added to Drugs Archive

Description: Originally published in Drug Metabolism and Disposition

Concludes that CY3PA4 (the one inhibited by grapefruit juice) is the dominant cytochrome enzyme involved in metabolism of ketamine

To check it out, rate it or add comments, visit Contribution of CY3PA4, CYP2B6 and CYP2C9 Isoforms to n-Demethylation of Ketamine in Human Liver Microsomes (Hijazi and Boulieu, 2002)
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