Snorting - Everything SWIY Needs to Know About Snorting Benzodiazepines

[Benzeneringz]

True, most benzodiazepines have no appreciable solubility in water. But "most" doesn't mean "all". A handful of benzodiazepines do have appreciable solubility in water. Temazepam is in fact water soluble, which means it can successfully enter the bloodstream through the mucous membranes of the nose and sinus passage.

Temazepam does indeed have a rapid onset of action when taken orally. But it has a more rapid onset when sniffed. Plus, you avoid first pass metabolism by sniffing the drug. Rectal administration is a lot like sniffing, but there are a few major differences between the two. Sniffing temazepam will result in a very rapid onset of action. The subjective effect is generally more intense: this is because the dose enters the brain virtually all at once. With oral administration, temazepam slowly diffuses into the brain at a constant rate. Rectal administration results in a quicker onset of action than oral delivery but a slower onset of action than sniffing. Rectal administration, like sniffing, avoids first-pass metabolism. However, the maximum amount of drug present in the body is highest with rectal administration. Sniffing gives a rapid dose of temazepam to the brain but has a shorter duration than rectal or oral. Rectal slowly gives you the highest peak plasma level and thus has a longer duration of action than sniffing. But since the "feel good" quality of any drug has to do with the time it takes to reach the brain. Since sniffing is quicker then rectal, it feels better. Trust me, I'm prescribed to temazepam and have done both.

[fiveleggedrat]

Snorting works for my cat. Xanax/alprazolam, specifically.

Swim's cat finds oral consumption, first dissolved in water, is the most efficient method for both benzos and opioids. His personal opinion, though. Snorting does not last as long, as is not always as intense.

[nefbass]

Has anyone ever snorted ativan... ive taken a few mg's by mouth before and it fucked me up pretty good, however the ouking and falling and fucking my ankle up wasnt the best part... but has anyone snorted it, and the results??

[Powder_Reality]

SWIM would like to know if snorting lorazepam is an effective route of administration? What are the effects and recommended doses for snorting it in comparison to oral administration?

[MrJim]

Lorazepam isn't water soluble, so snorting it isn't really a good idea. It won't dissolve in your mucus membrane, the only effects you'll get out of it are the drip down the back of your throat into your stomache, therefore you are better off administering it orally.

[Nahbus]

Sublingual ingestion. Break it up (lorazepams are small, you shouldnt have to) and put it under your tongue untill it's gone. Comes on much quicker.

[XCorruptX]

some lorazepam tablets are sublingual and some aren't... I took some lorazepam before and i just swallowed them, I never even heard of sublingual till reading this so could someone tell me if they were the sublingual kind would there be different effects and would this be bad to swallow it. thanx

[kapten]

SWIM.I experimented with this some time ago. Realising that most benzos are water soluble he decided to dissolve xanax in a weak EtOH solution which was added to a nasal inhalar.

After a few squirts his nose was burning like hell, but he swore that it was worth it ..... From the tears pouring out of his eyes though, I decided to give it a miss.

[baron samedi]

Is it true that Midazolam is the only snortable benzo? Would SWIM need a smaller amount than if taking it orally?

[demon_candy]

SWIM has found this thread interesting to read, though never much prefered insufflation as a method of consuming benzos or other substances alike. The only substance SWIM had insufflated before that she felt was worth the effects was a brand of common ADD medication containing amphetamine. Once the painful burn had subsided, SWIM could feel the effects very intensely.

But SWIM digresses, back to the topic. She has never had much experience insufflating benzos, and has generally preferred the oral route of administration. She thinks parachuting or holding a pill such as Alprazolam under her tongue is an interesting method, however the taste of some such benzos is quite terrible and more than SWIM can bear. She imagines other ways of consumption may lead to more immediate effects and perhaps more of an intense 'head-buzz' upon contact, but in many cases might not be too much stronger, or perhaps pleasant than taking it orally. She also wonders though, if an individual has adverse stomach reactions to such medications, if insufflation would perhaps remedy that slightly. Just a thought.

SWIM has heard rumors of xanax being taken in this method, especially with the use of alprazolam bars (2mg and up). She imagines that a user may well feel very intense effects from this, however she surmises that consuming a large quantity of any such benzo would have intense effects, possibly making a report of insufflation as being a better method somewhat biased, unless a comparison was made of the same amount taken in both methods.

At any rate, SWIM thinks that a big factor is just that like people like to snort stuff. She knows it's true too, because kids in high school used to snort pixie sticks. And then what happens when those kids grow up? Thus my point, lol.

[NEUROROGUE]

SWIM SNORTED.. XANAX 1 mg tab about 5 mintues ago. THe experience was a waste, since some is stuck in SWIMS nose and with prior knowledge that xanax is not water soluble. the pill drips, which goes into your stomach anyway. The effects were very mild comparing to swallowing it. The onset of the drug was quicker, but one would have to snort more to get the same effect compared to swallowing it. SWIM would def swallow it or stick under tongue. SWIMS doctor told SWIM that sticking it under the tongue would provide quicker onset of action. SWIMS doctor told me this, because SWIM was complaining that SWIMS DOCTOR did not provide enough for the month, so he just told me to stick under the tongue and it might provide quicker relief. DO NOT SNORT IT >>> IT IS A WASTE AS DID OTHERS say in this thread. Thank you for reading

[IHrtHalucingens]

i dont think there are sublingual kinds, u can administer any pill orally, sublingually, insuffated, and i guess IM and IV with some work. It just depends on the substance that is being taken whether one or another is better. Most benzos are not water soluble so not good to snort. however if u want the quicker acting effects then u can stick any pill under your tongue and it will enter the blood stream quicker. but last shorter. So it depends on the substance and your personal [preference.

[XCorruptX]

thanks but i have another question how does the water solubility effect snorting, does the pill have to be water soluable to feel the effects if you snort it..?

[IHrtHalucingens]

If the substance is not water soluble very little of it crosses the blood brain barrier which means you would need a higher dose to feel the same effects as popping it or dissolving it under the tongue. So basically its a waste of lorazepam to snort it and your are more likely to feel adverse affects of the drug because of the maount you must take nasally.

Reputation Comments on this post:

bypassing the BBB is not related to solubility. further, a specifically sublingual formulation of lorazepam has been mar...

[Nicaine]

SWIM just verified that lorazepam is insoluble in water -- and this immediately after snorting a tablet . WTF, this eliminates rectal administration as a possibility too, unless the stuff was dissolved in propylene glycol or something similar.

Edit -- it's interesting to note that the lorazepam SWIM snorted is having a pretty rapid effect anyway. It's certainly a much better quality of relaxation than he gets from clonazepam (the "sh*t sugar pill" of benzos, and nearly worthless as far as SWIM is concerned).

[Juicelvlan]

Do you get a better and more intense high when you snort xanax, or would it be better to just eat it whole? dont go by saftey precautions, just give me honest answer.

[IHrtHalucingens]

Xanax has poor solubility in water which means very little of it crosses the blood brain barrier. It would be better to eat it whole or dissolve it under you tongue. If you can take the taste dissolving it under your tongue is the quickest acting and most intense way mentioned, but of course its not as long lasting as eating it. If your open minded enough you should read my thread on administering xanax rectally. Good luck.

[oldman]

like IHrt said the taste of that stuff is pretty nasty, I can't imagine anyone being able to tolerate the drip personally. I'm not sure anything that lacks anesthetic properties is really worth the trouble of snorting. just my opinion.

[powderhead55]

i was just reading about benzos and that they cant be snorted because they dont dissolve "easily" in water and i had an idea

this might be totally wrong, even stupid if you want to go that far, but i know from my cocaine days that hot-railing is quicker to come on because the coke gets hot as it travels up the tube and dissolves easier into the membranes, could this work for benzo's? its basically the principle that most things will dissolve in water alot easier if heated

SWIM doesnt have easy access to pills and really doesnt want to waste the ones he has if this doesnt work, anyone want to give it a try and report? (since there have been a rush of snorting posts lately) thanks

[Nahbus]

SWIM is sticking to sublingual ingestion on these. Doubt any significant change will happen when hotrailing benzos.

[blondie8734]

From Wikipedia:

Nasal insufflation (often called "snorting") sometimes occurs, but due to the drug's chemical structure, it is not absorbed through the mucous membranes. Instead, the powdered tablets and mucous drip down the back of the throat into the stomach, where they are absorbed as they would have been if taken orally.

Therefore, insufflation of the drug is no more potent than when taken orally, and it often severely irritates the nasal passages.

Furthermore, nasal insufflation may be significantly less potent than other means of administrations on a dosage-per-time basis, because the mucous drip enters the stomach at a slower rate than traditional ingestion. Also, when the drug is snorted, the user often "passes out" into a deep sleep and later wakes up disoriented, having no memory of what occurred prior to sleeping.

[Octo42o]

Swim snots, but is it bad to for SWIM to snort Xanax

[Jatelka]

It may not be bad for SWIY, but it is a highly ineffective method of taking it!

Xanax is not water soluble, therfore any absorption is via post-nasal drip (yummy). Besides who wants wax, chalk and all the other binder crap up their nose?

[sourceman]

Originally Posted by jatelka

It may not be bad for SWIY, but it is a highly ineffective method of taking it!

Xanax is not water soluble, therfore any absorption is via post-nasal drip (yummy). Besides who wants wax, chalk and all the other binder crap up their nose?

This is exactly right. SWIY will only get the effects of the drip, and not all the material snorted even makes it to the drip! SWIY is wasting his pills.

Sublingual is a fast way to take xanax but tastes horrible! Someone in the thread reccommended plugging (up the butt) does this work with xanax? seems like a lot of work when it has very high bio-availability when injested.. Maybe some people like stuff up their butt, but I'd rather swallow, lol..

Also, friends don't let friend snort xanax!

[Colby]

SWIM snorts xanax but prefers to pop some b4 SWIM feels this is much more effecive than taking a large amount, get about 1mg in your system if you have a lower tolerance start with .5mg