Dose - How Much Coke Do You Use To Get High?

[Nicaine]

Originally Posted by Bwen

I would just like to know how much experiences users re-dose once the effects start to go away. I am a beginner with cocaine so I only do about*.2 of a gram*starting off.. When I re-dose I allways seem to do a smaller dose usually 15 mins later. I usually do .1 of a gram. How much do you guys start off with and when it comes to re-dosing how much do you usually do? Also how much usually do you consume on a night?


Also please say how often you re-dose

SWIM (this guy I know & post for here) tends to get really high for the first couple hours, then continually bump himself into a steady moderate buzz for most of the rest of the time, with occasional forays back into seriously wasted territory. Occasionally he'll let himself come part or most of the way down, then bump back up into a nice euphoric buzz.

This guy SWIM often consumes about half an 8-ball at a time (about one ball shared with a friend). Basically, he consumes whatever he has until it's gone. If that happened to be a kilo, he'd probably do the full kilo and make sure he had a coffin, last will & testament, & other pre-arrangements sitting in an easy to find spot. Edited by: Nicaine

[Bwen]

I would probably do the same Nicaine. If I had a huge pile of cola I would do it until I start to shake out of control then wait till I stop shaking and re-dose!

[IDidntDoIt]

Just wondering how much SWIM does in a usually setting or the most swim has done in one time...

SWIM does if alone maybe half a g.. sometimes up to a 16th..

a friend has done a whole 7 g's by himself

[matti_2003]

Depends really, Swim usually has around a quearter of a gram and then gets bored of the feeling and ends up taking something else. The most he has had was about 1.5 grams, the reason being that it was quite poor quality stuff.

[tre2005be]

swim n about 7 other lads normally get through about half oz on a friday then another half oz on the saturday. but swim is tryin to stop takin it, but to do that swim needs to stop drinkin which is a whole different problem.

[IHrtHalucingens]

SWIM usually enjoys an 8th for a night of being coked up, but if other drugs are being taken as well he can go as little as a half a gram for the night. SWIM in the peak of his use has done an ounce in four days. It was after that week that SWIM realized the power of the drug and decided to keep his use to one or two binges a year not exceding 5 days and a 1/2 ounce. He has stuck to that rule for 2 years now and finds he enjoys it much more this way.

[Bajeda]

Swim isn't a big fan of cocaine, though some of his friends are.

He very rarely does it alone, and prefers to do it with a bunch of people, preferably drunk.


Generally a gram a person equals a very fun night out on the town (or just partying at your own place).

Less works too, especially if all you want is an energetic drunk.


The most swim has done by himself is two grams over the course of a few hours. He tries to take care not to binge too much, given the addiction and monetary factors that make coke less desirable in his eyes in the first place.

[AceOvArts]

The most SWIM did was about 5g in a day/night probably a couple of years ago. A bad binge time that was, you can imagine the come down, I heard SWIM say "never ever again", he said how much he hated coke and how much he loved life. Yesterday SWIM did 3g *sigh*

[powderhead55]

Definitely depends on the crowd. If SWIM is out with friends who dont "approve" of cocaine, then maybe 1/4 gram a night. If everyone is doing it and everyone is just breaking up lines, an SWIM will kill an 8ball easily within a couple hours.

Most SWIM has ever done was about 6g's in one day. SWIM and his friends bought a ounce, sold enough to make their money back and planned on making it last a couple weeks. It lasted one day.

[tre2005be]

Originally Posted by powderhead55

Most SWIM has ever done was about 6g's in one day. SWIM and his friends bought a ounce, sold enough to make their money back and planned on making it last a couple weeks. It lasted one day.

swim knows the feelin, if its there it will almost definitely go...

Originally Posted by Bajeda

He very rarely does it alone, and prefers to do it with a bunch of people, preferably drunk.

swim is exactly the same, he doesn't see the point in taking a drug that makes him chat all night when no one is there to chat to.

[levdog]

Swim usualy buys 1 ounce, that lasts about 2-3 weeks. When swim goes out partying or drinking, he gets through about 1 ounce over a weekend period. Swim is a habitual user, he is using from the moment he wakes up to the moment he goes to sleep. This is because of how swim lives his life, and his job. Swim is a cameraman for various bands and musical artists, and is touring for about 50 weeks a year. Because of the nature of the job, it is pretty much assumed by everyone in swims line of work that everyone else is also using like this. Most tours organise the cocaine in diferent areas they travel as though they are booking a hotel. A habit like this costs around 70 *flamingos* a year. I cannot obviously say the price, SO I WON'T!

Edited by Jatelka: Prices are only OK in the context of an article/news report with a quoted source

[adzket]

swim at first used to be able to make a gram last about 18hrs of partying with other drugs. at one point they stuck 3/4g up there nose in one go because they poured it out in a club for friends to share and threw bag away friends only had a little swim said they could have what they wanted but then ended up with 3/4 left and no where else to put it. swim then a bit later had a very buzy life working 80-90hr weeks and partying most of the rest during the week they wold do upto 5g a night at weekends they would do 1/4 oz between sat night to erly monday morning swim got very parinoid and moody this was not good lost many friends ect.

[Jatelka]

SWIJ does hope that this isn't going to turn into one of those dick sizing threads:

Remember "peeps" that taking large amounts of drugs is neither big nor clever (and no-one is really interested). Some extrapolationon re reasons,the effects on one's life/nose etc is needed!

[bunk8017]

swim wishes she knew how big all these measurements actually are...

[Beltane]

About 10 years ago SWIM went through a year of heavy meth use. He used about daily, staying up between 3 and 5 days on average, sleeping for a day or two and then starting up again.

He did great at work, got promoted twice and then hired away to another company that was a way better job.

Finally he realized how dangerous it was (had little access to info then,) so he quit. In the 10 years since he's done it 3 times, all in a 2 day period, so he's pretty done with it.

Anyway, years later SWIM gets into Coke. He sees others use some, stay up until 4am and go to bed. SWIM himself usually finds himself staying up all night and for the next day or two with no sleep at all as if coke were meth.

But meth is made for staying up for days where coke is not. So he ends up sloppy with a messed up nose. Not really getting high like he was, but not wanting to stop.

Anyway, that's SWIM's private hell. Just wondering if anyone else ended up the same way by starting on meth and switching to coke.

BTW, IV use solves the nose issues and the not getting high, but coke still doesn't seem well suited for staying up days in a row the way meth is.

Comments?

- Beltane

[spacing-dopey]

I don't really know where to place this topic, but so I'll just try posting it here.


I've been doing some research on crystal meth andn crack on the internet, but I'm still not exactly sure what the difference is between crack and crystal meth. From what I research I figured that crack is the smokable form of cocaine and crystal meth the smokable form of speed.

Could someone please correct me if I'm wrong or tell me what the the true differences are between crack and crystal meth if I am wrong. thanks

[fnord]

hmmmm crack is freebased cocaine, meth is methamphetamine,while there both speedy i dont feel like going into it too far,seeing aS this could of been solved by useing the search engine.but meth is long acting speed, crack is short acting.both produce euphoria and paranoia among its users.neither drug makes a good hobby if used more then once and a great while.for more info on thier effects try google or wikipedia

[eon_blue]

SWIM is wondering if an aquired tolerance to cocaine will create a tolerance to Adderall as well?

Reason SWIM is asking is because after a couple months of "regular" cocaine use (3-4 times a week), SWIM has developed a tolerance to the stuff. Recently, he took 30mg of IR Adderall (instant release), and felt next to nothing. Before cocaine, 30mg of Adderall would have SWIM feeling pretty good (not tweaked).


SWIM knows that Cocaine is not an amphetamine whereas Adderall is...but is it possible to develop a cross-tolerance from one to the other? Or is SWIM just not "feeling" the Adderall because subconciously he's expecting it to be just like cocaine?

Thanks in advance

[SWIMming]

Multiple things could form a cross tolerance there -

First of all, Amphetemine and Cocaine are both stimulants, and create their effects in the same channels (Dopamine, Norepinephrine, and a bit of Serotonin).

Standard, physical tolerance to these drugs is mostly through 'depletion' of these transmitters (which is short term, for the most part, 2-4 days of so with sleep/good diet(protein)/etc. The other form of (longer term) 'physical' tolerance is through damage of the neurons in play with these drugs, which can cause significant long term tolerance (as well as the long term withdrawal/depression/craving symptoms - these are SWIY's reward pathways).

Then there's mental tolerance - also probably in play. Essentially SWIY doesn't feel/enjoy the low dose/weaker drug kick after the bigger rush/euphoria/effect of the higher dose/stronger drug.

This is SWIM's understanding of stimulant tolerance, correct SWIm if he's wrong on anything!

[Bio-Cellular Enigma]

Originally Posted by SWIMming

The other form of (longer term) 'physical' tolerance is through damage of the neurons in play with these drugs, which can cause significant long term tolerance (as well as the long term withdrawal/depression/craving symptoms - these are SWIY's reward pathways).

Fwiw, SWIM believes there's a debate raging about whether "long term tolerance" is related to neurological damage or not. It seems to be substance-dependent, and some forms of long-term tolerance may be due to receptor down-regulation (which can take very significant amounts of time to return to normal) and possibly other homeostatic brain mechanisms.

SWIY is probably right about long-term tolerance caused by methamphetamine, but SWIM believes there's a lot of disagreement about cocaine.

By the way, the answer to the OP's question is yes - cross-tolerance between stimulants is very common, particularly those that work via approximately the same mechanisms (some) and affect the same neurotransmitters (most).

[epote]

Fwiw, SWIM believes there's a debate raging about whether "long term tolerance" is related to neurological damage or not. It seems to be substance-dependent, and some forms of long-term tolerance may be due to receptor down-regulation (which can take very significant amounts of time to return to normal) and possibly other homeostatic brain mechanisms.

yeh, the "steps" of tollerance are transporter protein upregulation->degenerative enzymes upregulation->post synaptic receptor dencity reduction-> completely changed neuronal pathways

its called neuroplasticity, there is a theory that long term receptor downgrade can be permenant, but you can never be too shure...

and aderal will have cross tolerance with cocaine obviously, they work differently but in the end they both affect mainly dopamine

[Bio-Cellular Enigma]

^ Thanks for clarifying. Does SWIY know if there are any significant studies (either complete or in progress) existing on this topic, particularly anything posted on the Web?

Also - would the steps SWIY listed be the same for reuptake inhibitors and "flooding" drugs such as methamphetamine, or are there important differences? SWIM would guess most of the debate lies in the area of reuptake inhibition, as it would see there's less chance of neurotoxicity.

[epote]

well the net effect is an increase in dopamine which the body doesnt really like, regardless of the method this hapens (DAT antagonism or dopamine displacement in the presynaptic vesicle) the net effect is increased dopamine presence in the synaptic cleft.

the body will initially try to reduce it by increasing transport proteins etc and eventually by downregulating the receptors. I would guess that in the case of amphetamins and ampetamine like drugs the tollerance would take longer to be established because the increase in DAT's would somewhat compensate for the increase in dopamine because it isnt antagonized by anything (like cocaine). But it would eventually hapen.

i couldnt find and research, i will try again later

[epote]

it is very common for most if not all people who try for the first time a dopaminergic stimulant (cocaine, amphetamins etc) to feel nothing. Obviously its the fact that the user is scared of dosing properly, but this study fell into my attention while browsing:

[top]Effects of blockade of NMDA receptors and NO synthase on the expression of associative and non-associative sensitization to effects of cocaine.

Grönig M, Atalla A, Kuschinsky K.
Institute of Pharmacology and Toxicology, Faculty of Pharmacy, University of Marburg, Ketzerbach 63, DE-35032 Marburg, Germany.
After repeated administration of psychostimulant drugs, a sensitization rather than a tolerance to the behavioral effects can be observed. In our own previous studies, it was shown that both blockade of NMDA glutamate receptors and inhibition of NO synthase selectively inhibited the expression of associative but not non-associative sensitization to D-amphetamine. The present experiments were performed in order to study whether a similar selective inhibition of expression of associative sensitization to cocaine can be observed after blockade of NMDA receptors by MK-801 or inhibition of NO synthase by L-NAME. MK-801 as well as L-NAME inhibited the locomotor activity in acutely cocaine-treated rats. Both drugs did not prevent the sensitization either in the associative or the non-associative group. The results suggest that the acute locomotor effects of cocaine were inhibited by both drugs whereas both the non-associative and the associative sensitization to locomotor effects were not inhibited by blockade of NMDA receptors or inhibition of NO synthase. Accordingly, the expression of neither type of sensitization to cocaine was inhibited by any of these drugs. Copyright (c) 2006 S. Karger AG, Basel.
PMID: 16837778 [PubMed - indexed for MEDLINE]

the NMDA receptors are inotropic receptors which when activated allow for the non selective passage of cations. This is interesting because the neurons release neurotransmiters is mediated by voltage gated ion chanels which would be stimulated by the release of cations that the increase in NMDA receptor sencitivity which is conjectured to happen in this study.

ergo, the first time your body just doesnt release enough dopamine to cause a significant high, but later on as use persistis this along with other factors which are described in the cocaine basiscs topic would atribute the increase in potency (?)

discuss obviously

[tigerdude]

SWIM rides the white stallion about twice a month (used to do it much more in the Spring). Over the summer, SWIM legally began taking adderall for ADD. Both are amphetamines. Is anyone "sciency" enough to maybe explain it? SWIM now hardly feels it, but has recently read some experiences that claim that Wellbutrin lowered their tolerance level to a certain extent. Any thoughts?