Health - How Dangerous is Cocaine Use?

[Jatelka]

Eniacoc
Coke can be taken pure and in large lines, unlike common belief. For a 90kg human it takes around 7 grams to kill him (if one doesnt have heart or liver problems, or doesnt mix with anything else). Usually dealers make up this lie as an excuse for the excessive cut.

SWIM thinks (oppinion) that snorted coke is unlikely to kill by OD - the body (and nose) gives up earlier because the absorbed dose is much less than the ingest dose, but indirect problems (heart, liver, stroke) can happen in less healthy individuals. Smoked is the same (maybe a bit more is absorbed and faster), but IV is dangerous as any other drug - once injected, it's done, no turning back so be VERY careful.

As an oppinion, SWIM also thinks coke is only mentally addictive, not physically. No one can talk about this for sure as it is an extremely variable subject. SWIM thinks cocaine is a "24h addiction" drug - once you sleep you will be ok. Dont abuse it on a hard time of your life, that can make you think about it after you sleep, which isnt good.

Only some conclusions SWIM had in a dream... SWIM is sorry for the long post but he hopes it's useful for someone. If wrong please discuss.

Cheers

Does SWIEniacoc have a reference for "for a 90kg human it takes around 7g to kill him"?

Just so all SWIY's know the figure quoted above seems high, given that oral LD50's are stated in various places as being 1.5g (and SWIJ STILL hasn't been able to find a reference for that one either!)

When we're talking toxicity/fatality stats we need some science people!

[eniacoc]

Google "cocaine ld50" and you find even higher ld50 doses than what was said by SWIM. As much as 90 to 100 mg/kg (intravenous) is the ld50 for pure cocaine, this has been tested many times in mice. The control populations are healthy of course. Dont forget this is the toxiciy levels and that ld50 is the average. Most deaths are by indirect causes (heart attack and stroke caused by body stress) and not by an intoxicated organism.

SWIY said "oral dose" - that seems pretty outlandish since only about 20% are absorbed once it is taken in this fashion. The rest is hydrolized into ecgonine it the stomach, and this is not even active.

SWIM would have died several times if this was true

Originally Posted by jatelka

Does SWIEniacoc have a reference for "for a 90kg human it takes around 7g to kill him"?

Just so all SWIY's know the figure quoted above seems high, given that oral LD50's are stated in various places as being 1.5g (and SWIJ STILL hasn't been able to find a reference for that one either!)

When we're talking toxicity/fatality stats we need some science people!

[Jatelka]

Ok: Seeing as SWIJ has to do all the work round here.

From inchem.org:

"Lethal doses are estimated at 0.5 to 1.3 grams per day by mouth; 0.05 to 5 grams per day by the nasal route, 0.02 grams of cocaine by the parenteral route (Baschard & Richard, 1984; Haddad & Winchester, 1990;
Burnat & Le Brumant-Payen, 1992).

Cocaine addicts can tolerate doses up to 5 grams per day. Toxic effects can be manifest with plasma concentrations equal to or above 0.50 mg per litre; deaths have been reported with concentrations of 1 mg per litre (Clarke,
1986)."

Mice are not humans, it is disingenuous (and potentially dangerous) to extrapolate human doses from animal LD50's. The little buggers are remarkably resistant to the toxic effects of many drugs.

You talk of "body stress" as if it is seperate from the effects of cocaine. Strokes and Heart attacks are caused by hypertension and coronary artery spasm, BOTH OF WHICH are direct effects of cocaine.

Bear in mind that many people may read these pages and take it as simple fact. They may not be arsed to Google Search. Therefore backing up your statements here with references is a means of harm reduction.

Please consider this in future.

Reputation Comments on this post:

Thanks for fixing the facts

[eniacoc]

About the ld50, i've read more about it and in fact the human tolerance seems lower in many documents, although there doesnt seem to be much agreement on this, maybe because of the lack of ld50 human volunteers (hehe) and also because it's almost impossible to evaluate the total dose in the fatal cases, even when it's possible to know how many grams have been taken (street drugs vs lab drugs, mice are always tested with lab coke, virtually 100% pure so statistics are precise).

Sorry about jumping to conclusions and post such a dangerous number as if it was a fact. But the reality is that the values you state seem a bit low to SWIM or even more to some people SWIM knows of, maybe because these values rise with tolerance, but it's always safe to stay on the low side rather than abusing it.

The truth is that people see two opinions and usually go for the one that they like the best instead of searching for medical facts. Read and learn.

[zaraza777]

SWIM knows that drinking alcohol while doing cocaine is dangerous. But what amount of each one is dangerous? Is it more dangerous taking 3 lines of cocaine during a period lets say 2 hours and drinking 2 beers - or drinking 5 beers and do 2 line of cocaine? Or meaby that doesn't matter and the only thing that matters is that the 2 substances were mixed. Things like that.
Drinking any alcohol with cocaine is obiously dangerous. But which alcohol is more dangerous when mixed with cocaine? Is it beer, whiskey, vodka etc, or meaby the kind of alcohol does not matter and only the amount consumed matters.
What are symtoms of taking to much cocaine and alcohol together? When should a person that is using fhose 2 things be concerned?
Any answers and info would be very appreciated as I would like to answer SWIM question in the best possible way and pass some knowledge to him.

I tried the Search in this forum bo coudn't find any helpful info.

Although I live in the USA English is my second language so please excuse my spelling errors and any other mistakes. SWIM should have wrote it because he speaks better English lol
If Moderator finds these questions silly or stupid please delete this thread.
Thank you.

[ProteinBlast]

Hi Zaraza, SWIM knows that everyone is different and depending on a myriad of factors (age,height,weight,tolernace, etc.) the outcome can be different. For SWIM, whenever the stuff came 'round, it would be about 3-5 beers first, THEN a few lines, then drinking throughtout. Sometimes the number of beers would be greater, 5-8 range. After the cocaine starts kicking in good, the drinking slows down dramatically.
SWIM is very aware of the bad combo created by mixing both (more damage to the liver and heart), but SWIM has found that he was unable to truly enjoy the cocaine without a few beers first.
SWIM would often enjoy a 12 pack of light beer and about a gram for a typical "party" night. But again, everyone is different.

[surf1284]

SWIM has a questions pertaining to this subject.

SWIM has gotten comfortable to only doing coke while drinking. He'll usually just go to a party with some beers, and if anyone there has some cola he'll do a line or two, and than finish off the night with some more beers. He is comfortable with doing this because it makes getting to sleep much easier.

The question is SWIM and his friend are planning on buying a g for the upcoming vacation, but of course wants beer to help him get to sleep.
They will be doing half the g each and than say half a 12-pack each.

Now 6 beers is not by any means a lot for SWIM, but is not used to doing that while sniffing .5 a g.

My question here is, if he does cola all night and than waits at least an hour after his last line, is it still dangerous, or is it significantly safer than doing both at the same time?

[dolphinsnow18]

concerning hread cuz SWIM has always drank JD to come down form lining. Never had any issues though

[KomodoMK]

SWIM and friends have done large amounts of cola each, like eights over the course of 6 hours with loads of alcohol, usually stella and not once ever had a problem.

While it can be dangerous, it very rarely is, and SWIM has never known anyone to have a problem and SWIM knows a lot of people in this scene.

I would advise against it though, because everyone is different, just because in my experience it has never been a problem, it by far doesn't mean it isn't. The best advice I can give you is follow your own body and mind.

[surf1284]

My question still is, if you wait for the high to go away, and than drink alcohol is it still as dangerous? Or is just just bad when your mixing them at the same time?

[jojadi]

Here in Colombia most people drink and do cola at the same time, that's the beauty of the two, never heard any problems related of mixing the two.

[goingmerry]

hypotheticaly speaking, SWIM is in his teens and has experiemnted with cocaine on a small number, maybe 4 or 5, of occasions consuming about .5g each time. SWIM is alos afrequent weed smoker, has used xtc a couple times, adderal + alcohol, among other things but all in moderation. SWIM wants to know if this could have an impact on SWIM's developing brian? or no because it was done so few of times? thanks.

Reputation Comments on this post:

swiy needs to begin studying drugs in general before using anything

[edoggg]

doubt it. considering you only did it a few times, theres really no chance of it fucking with youre developing brain. if you started hitting it really heavy like addict steez then maybe, but you got nothing to worry about.

[beena]

SWIM has always mixed drink and drugs (sometimes to foolish levels), but she couldn't deal with a cocaine comedown without alcohol. I think the main issue with combining these two substances is that they create another chemical called coethylene and this is extremely damaging to the liver. So combining coke and alcohol in the long term is not good and I don't think it matters whether you drink during or after your session.

[Skinny girl]

Hi all. I am new to this site, just joined this morning actually. I have just start snorting cocaine. I did it a few times, a little bit about six weeks ago and then last weekend over like three days I did three grams by myself which is a little alarmng for me because I intended to save some and everyday I just kept going for more. Well, tonight I got four grams and am wanting to space the use out over days but between 11:00pm and about 4:30 am I ended up doing probably a little more than a gram already in little increments. My question is, how danerous is what I just did? I know, a little late to ask but of course now I'm freaking out about it. I haven't done it in about two hours but I worried that something is going to happen to me, even if I try to sleep a little. I won't die or OD in my sleep will I? I know this is probably irrational but I'm scared. Also, I am planning on doing some tonight for a concert and maybe at little in a few hours when I wake up to get me going. Is this alright and how I can I do recreationally without it getting out of hand.?

Thanks for your help.

[Pinkavvy]

Click on the green link above that says Forum Rules and read them, please. Self-incrimination is now allowed. Admiting to using drugs on an open forum like this is like calling your local police department and telling them.

Learn the word "SWIM" and use it.

[Micklemouse]

Originally Posted by Pinkavvy

Self-incrimination is now allowed. Admiting to using drugs on an open forum like this is like calling your local police department and telling them.

Learn the word "SWIM" and use it.

Should I think read "...not allowed."!

[Sitbcknchill]

Originally Posted by Skinny girl

Hi all. I am new to this site, just joined this morning actually. I have just start snorting cocaine. I did it a few times, a little bit about six weeks ago and then last weekend over like three days I did three grams by myself which is a little alarmng for me because I intended to save some and everyday I just kept going for more. Well, tonight I got four grams and am wanting to space the use out over days but between 11:00pm and about 4:30 am I ended up doing probably a little more than a gram already in little increments. My question is, how danerous is what I just did? I know, a little late to ask but of course now I'm freaking out about it. I haven't done it in about two hours but I worried that something is going to happen to me, even if I try to sleep a little. I won't die or OD in my sleep will I? I know this is probably irrational but I'm scared. Also, I am planning on doing some tonight for a concert and maybe at little in a few hours when I wake up to get me going. Is this alright and how I can I do recreationally without it getting out of hand.?



Thanks for your help.

Well in my opinion I do not think you will die. Next time only buy what you intend to use. Most people can not cut themselves off when need be so this way you have to cut yourself off. Unless the dealer is right next door .

Anyways you should be fine...

But take note that your recreational habit sounds like it will be just a habit in no time. Be careful, cocaine is a hard monkey to beat off your back.

Stay safe

BTW, welcome to the forum skinny.....

[Skinny girl]

SWIM apologizes for not following forum rules in previous post. SWIM obviously was hyped up and nervous and didn't read the rules. SWIM will not let it happen again. SWIM obviously turned out fine and did not die. SWIM is learning moderation is key.

[mouthwater]

Young people who abuse cocaine and amphetamines are at heightened risk for suffering a stroke, a study published Monday confirms.

Cocaine, amphetamines, and other stimulants may boost the risk of stroke by raising blood pressure or by triggering spasms in blood vessel walls.

Dr. Arthur N. Westover of the University of Texas Southwestern Medical Center at Dallas and colleagues analyzed data on strokes and drug dependence or abuse from Texas hospital records for the period 2000 to 2003.

A total of 8,369 strokes occurred during the 4-year period, the investigators report in the Archives of General Psychiatry.
In the year 2003, amphetamine abuse was associated with a five-fold greater risk of "bleeding in the brain" stroke -- called hemorrhagic stroke -- but not ischemic stroke -- the kind caused by a blockage.

Cocaine abuse more than doubled the risk of both hemorrhagic and ischemic stroke.

Amphetamine, but not cocaine, abuse was also associated with a higher risk of death after a bleeding stroke, according to the team.

"The public health implications of these findings are heightened by growing news accounts suggesting a recent increase in methamphetamine abuse, particularly in the southwestern, western, and Midwestern states," write Westover and colleagues.

"This concern," they add, "was supported by our finding that, among hospitalized patients in Texas in 2000 to 2003, the rate of amphetamine abuse was increasing faster than that of any other drug, including cocaine, and the rate of strokes among amphetamine abusers was increasing faster than the rate of strokes among abusers of any other drug."

Stroke a risk for cocaine, amphetamine users
Reuters Health
Monday, April 2, 2007
SOURCE: Archives of General Psychiatry, April 2007.
As found on MedlinePlus.

Reputation Comments on this post:

good example of research and interest in personal health

[T-Virus]

SWIM is very confused about the effects of snorting cocaine. SWIM has snorted cocaine once, spending 20 dollars on just enough for a couple of small lines.

SWIM also spent much time reading threads about the bad effects of I.V's. SWIM is curious if snorting small ammounts of coke will have effects like the seizures that many are apparently dying from on I.V's.

SWIM has spent alot of time attempting to research the drug, but wants to know the effects it can quite possibly have on occasional usage of the drug.

SWIM apologizes if this has been asked before and or if this information has already been covered, swim just wants lamence term answers.

-apologies for typos.

[DoomFarmer]

Occasional usage of cocaine seems to Swim to have no more than psychological effects

[vantranist]

SWIM doesnt expeirnce much besides a comdown (pycological) lasting for a few hours after the use, Depending on how much he used.

With long term use there will def. be some physical problems for most users, some small some big.