The Holy Grail of Opiates - Opinions?

[MrJim]

Originally Posted by nks

What about the OC160s? Can't believe no-ones mentioned those?

Kiddie Killers, as they were nicknamed, were discontinued a few years ago.

[VincentVan]

Hey,
you know what?
This thread is just no good for me.

Reputation Comments on this post:

What's that about? You should have given more info

[hh339]

SWiM has not tried Diacetylmorphine, but so far these are his holy grails:

1. Oxymorphone, followed closely by
2. Ketobemidone

He's not really into Opiates, but these ones were really nice.

[Handle]

Originally Posted by hh339

SWiM has not tried Diacetylmorphine, but so far these are his holy grails:

1. Oxymorphone, followed closely by
2. Ketobemidone

He's not really into Opiates, but these ones were really nice.

Hahah, ketobemidone, that is sposedah be like the surprise ultimate hit!? Whoda thunkit? SOme say it enforces addiciton better than heroin, but where does the truth lie?

Handle added 3 Minutes and 39 Seconds later...

Originally Posted by pipolito

SWIM would guess the real Holy Grail would be opioid peptides, which create in your brain what is basically a pure opiate high.
SWIM would never even probably have had learned about it if it wasn't for this very same site.

Opiorphin seems to be the holy grail of the new generation of opioids.

Swim had these, and they are amazing, but not what you'd expect, not sedating, no pinpoint pupils, and very short lived. But AMAZIng, swI-m-ust say.

You definitely get the euphoric rush, but it's more stimulating, if you'd believe htat, then it's all gone in five minutes.

[machine_elf]

Swim would love to get his hands on a brick of freebase morphine....

[Orchid_Suspiria]

Swim would loveeee to get his hands on some of that pure,pharmaceutical diacetylmorphine they make in the UK.That is his grail,as far as things swim has tried the fentanyl 100 mcg patches kick alottt of ass!

[OhCasey]

Swim would love a pallet of 160 ocs and he'd retire from life. I know someones got 160's stocked up somewhere. Maybe in some foriegn land.

[keats]

SWIM would say opium might have turned into the holy grail of opiates in the US, which is ironic since it's the original and least refined. Still, it's definately easier to locate heroin, oxycodone, and even fentanyl in a big city these days than it is to score pure opium, in SWIM's experience. As someone else already mentioned though, what you can buy is poppy pods to make tea, which is the closest thing to opium SWIM has been able to locate regually.

[Bio-Cellular Enigma]

Originally Posted by keats

SWIM would say opium might have turned into the holy grail of opiates in the US, which is ironic since it's the original and least refined. Still, it's definately easier to locate heroin, oxycodone, and even fentanyl in a big city these days than it is to score pure opium, in SWIM's experience. As someone else already mentioned though, what you can buy is poppy pods to make tea, which is the closest thing to opium SWIM has been able to locate regually.

That is in fact opium, in an oral-only form (unless highly distilled) and still within the plant matter. According to some reports, SWIM is not sure it's any kind of holy grail, but it may in fact be "holy hell" addiction-wise.

[hoodabudda]

swim would have to say a pharmacy bottle of old oxycontin 160mg tabs *pops boner*

[Daytona71]

SWIM is currently using oxymorphone, 12 x 10mg. IR tabs/day and soon a couple of ER's to be replacinmg the 90mgs. of methadone. Nothing gives warm and fuzzy anymore. The holy grail may be clean and sober.

Reputation Comments on this post:

You're dead right about clean and sober being the Grail

[kheetah]

Swim's holy grail of opiates is heroin (diamorphine) because its be here since 1874 before alot of the opiates we see today and still kicks ass.

[H Bomber]

SWIM is putting his money on either Oxymorphazone or Etorphine


Wikipedia says-

Oxymorphazone is an opioid analgesic drug related to oxymorphone. Oxymorphazone is a potent and long acting μ-opioid agonist which binds irreversibly to the receptor, forming a covalent bond which prevents it from detaching once bound. This gives it an unusual pharmacological profile, and while oxymorphazone is only around half the potency of oxymorphone, with higher doses the analgesic effect becomes extremely long lasting, with a duration of up to 48 hours. However with repeated doses, tolerance to the effects develops rapidly, as chronically activated opioid receptors are rapidly internalised by β-arrestins, in a similar manner as occurs with non-covalent binding by agonists with extremely high binding affinity such as lofentanil.


Etorphine (Immobilon or M99) is a semi-synthetic opioid possessing an analgesic potency approximately 1,000-3,000 times that of morphine depending on the situation. It was first prepared in 1960 from oripavine, which does not generally occur in opium poppy extract but rather in "poppy straw" and in related plants, Papaver orientale and Papaver bracteatum. It was later reproduced in 1963 by a research group at Macfarlan-Smith and Co. in Edinburgh, led by Professor Kenneth Bentley. It can also be produced from thebaine.Etorphine is most often used to immobilize elephants and other large mammals.

Reputation Comments on this post:

	Interesting Compound, never heard of it
	The first paragraph of this post is remarkably informative. Excellent

[MrJim]

They are all "holy hell" addicition wise. One thing SWIM has noticed is that tea has a slower come up and come down, and because of that for him it is a less compulsive drug. Lines create stronger initial cravings. Maybe others have a different experience, but SWIM can drink tea and let the box sit for days on end, but can't stop lines until they are all gone.

[Laudaphun]

If fact they have reintroduced the 160mg oxys into the market or are planning on doing so, as well as adding new dosages. such as 15, 30, and 60mg. I actually was able to confirm this from a new package insert. It says 60mg, 80mg, and 160mg for opiod tolerant people only... and the usual..

The 10 mg tablets also contain: hydroxypropyl cellulose.
The 15 mg tablets also contain: black iron oxide, yellow iron oxide, and red iron oxide.
The 20 mg tablets also contain: polysorbate 80 and red iron oxide.
The 30 mg tablets also contain: polysorbate 80, red iron oxide, yellow iron oxide, and black iron oxide.
The 40 mg tablets also contain: polysorbate 80 and yellow iron oxide.
The 60 mg tablets also contain: polysorbate 80 and FD&C Red No. 40 Aluminum Lake
The 80 mg tablets also contain: FD&C blue No. 2, hydroxypropyl cellulose, and yellow iron oxide.
The 160 mg tablets also contain: FD&C blue No. 2 and polysorbate 80.

HOW SUPPLIED

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 10 mg are round,
unscored, white-colored, convex tablets imprinted with OC on one side and 10 on the other.
NDC 59011-100-10: child-resistant closure, opaque plastic bottles of 100

NDC 59011-100-20: unit dose packaging with 10 individually numbered tablets per card; two cards per glue end carton

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 15 mg are round,
unscored, gray-colored, convex tablets imprinted with OC on one side and 15 on the other.
NDC 59011-815-10: child-resistant closure, opaque plastic bottles of 100

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 20 mg are round,

unscored, pink-colored, convex tablets imprinted with OC on one side and 20 on the other.
NDC 59011-103-10: child-resistant closure, opaque plastic bottles of 100

NDC 59011-103-20: unit dose packaging with 10 individually numbered tablets per card; two cards per glue end carton

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 30 mg are round,
unscored, brown-colored, convex tablets imprinted with OC on one side and 30 on the other.
NDC 59011-830-10: child-resistant closure, opaque plastic bottles of 100

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 40 mg are round,

unscored, yellow-colored, convex tablets imprinted with OC on one side and 40 on the other.
NDC 59011-105-10: child-resistant closure, opaque plastic bottles of 100

NDC 59011-105-20: unit dose packaging with 10 individually numbered tablets per card; two cards per glue end carton

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 60 mg are round,
unscored red-colored, convex tablets imprinted with OC on one side and 60 on the other.
NDC 59011-860-10: child-resistant closure, opaque plastic bottles of 100

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 80 mg are round,

unscored, green-colored, convex tablets imprinted with OC on one side and 80 on the other.
NDC 59011-107-10: child-resistant closure, opaque plastic bottles of 100

NDC 59011-107-20: unit dose packaging with 10 individually numbered tablets per card; two cards per glue end carton

OxyContin® (oxycodone hydrochloride controlled-release) Tablets 160 mg are caplet-shaped,
unscored, blue-colored, convex tablets imprinted with OC on one side and 160 on the other.
NDC 59011-107-10: child-resistant closure, opaque plastic bottles of 100

NDC 59011-107-20: unit dose packaging with 10 individually numbered tablets per card; two cards per glue end carton

Anyone just soil their drawers? =)

[MrJim]

Jesus, I thought that they weren't going to do those anymore. I do hope they don't prescibe them except for the most desperate of situations...too many people see a pill and think "How can one hurt me? They are made by a pharmacuetical company after all..."
I just don't trust the average street user not to tarnish opiates reputation any more than it already is.

[Herbal Healer 019]

Originally Posted by MrJim

Jesus, I thought that they weren't going to do those anymore. I do hope they don't prescibe them except for the most desperate of situations...too many people see a pill and think "How can one hurt me? They are made by a pharmacuetical company after all..."
I just don't trust the average street user not to tarnish opiates reputation any more than it already is.

Yet another problem with drug prohibition and more specifically D.A.R.E and abstinence intent propaganda. If harm reduction & education based programs were introduced to main stream society, less people would say "dam I jus found an OC160, it's not an illegal drug so I'll b good if I pop it" & more would live.
Legalization is the only way & education is key. Bcuz when people aren't spoon fed lies & truthfully introduced to unbiased facts they realize that every drug has the potential to be safely used recreationally

As for the holy grail, from what I've heard it's Oxymorphone, but from a friend of a friend's experience, it's without a doubt OxyCodone.

[pipolito]

SWIM would guess the real Holy Grail would be opioid peptides, which create in your brain what is basically a pure opiate high.
SWIM would never even probably have had learned about it if it wasn't for this very same site.

Opiorphin seems to be the holy grail of the new generation of opioids.

[Bajeda]

160mg of OC is insane. They better have a picture of satan on the pill or something so people get a hint not to take it without a high opiate tolerance!

And they come in bottles of 100??

[Laudaphun]

At least they say they are child resistant.. lol

I've read that supposedly that "this time" the 160mg dosage pills will be regulated more strictly than the rest of the oxycontins... Basically, I think the government will or at least will try to make sure that they aren't being given out too casually... not that any oxycontin should be given out casually. Regardless of what the government does, someone is going to steal some of them off of their grandpa or grandma who is dying of cancer. I knew a girl that knew a girl that dropped dead from taking 1 and she swallowed it whole.

I've yet to really hear or see that they've actually been put back on the market but that package insert is legit so. At least know the public in general is more aware that oxycontin is not "just another pain pill"

If I had to guess, unless the government does take effective measures to keep them out of the hands of kids, or at least off of the street, they will be removed from the market again. To me it would have made more sense to make a 100mg dosage unit or a 120mg dosage unit.

I'll be curious to hear how this turns out... Unfortunately, the town I live in was a heroin-naive town for the most part up until about 10 years ago. Even the big shots claimed they'd never seen the big "H"... Then they came out with OCs, which alot of people were much more trusting of since it was as you said,

made by a pharmacuetical company after all

and a lot of kids got turned on to them. Kids got hooked on those, then discovered heroin was a pretty close feeling, but much cheaper and ALWAYS available in the city... no need to wait for so-and-so to get their script filled. So now the all the hype everyone was making about OCs has died down... Most people just switched to H. Surprisingly in the general surrounding area there have only been a few ODs that I recall... one that got blamed on oxy, but I think the kid actually ate a fentanyl patch.

BTW I have PDF files for 2 different package insert, both are legit, one is from 6/06 which lists all the new dosages... The other dated 1/07 and lists 10,20,40,80,160... If a mod is interested I can provide the PDF files to both or give address of them and perhaps make more sense of this than me.

[MrJim]

We have a file archive that you could upload them into. There is no bad knowledge out there, after all.

[Orchid_Suspiria]

Swim has taken up to 140 mg of oxycontin at times and been perfectly okay.It does worry swim that some kid with no real experience in opiates other than maybe a vicodin from time to time is going to get his hands on one of these 160 mg oxycontins.It's safe to say that kid would be in for more than he bargained.

[Salvinorin A]

Uh, wouldn't the opiate holy grail be one that doesn't cause any withdrawal....and that isn't addictive. At least that way it's more historical..no one's going to be finding it....cus it doesn't exist! (or does it?)

Unless we go Davinci Code on ur ass.... (I'll leave this one to ur imagination)

Sal-A

[toe]

Originally Posted by Salvinorin A

Uh, wouldn't the opiate holy grail be one that doesn't cause any withdrawal....and that isn't addictive. At least that way it's more historical..no one's going to be finding it....cus it doesn't exist! (or does it?)

Unless we go Davinci Code on ur ass.... (I'll leave this one to ur imagination)

Sal-A

Do a search for "oxytrex".

[machine_elf]

OXYTREX™
We are developing Oxytrex as an opioid painkiller with minimal physical dependence. Oxytrex is currently in a Phase III clinical trial.
Scientists at Albert Einstein College of Medicine have published results in numerous peer-reviewed technical journals suggesting that opioid painkillers activate an excitatory signaling pathway linked to opioid receptors, which stimulates the transmission of pain. This excitatory pathway counteracts pain inhibition and is believed to be a major cause of adverse side effects associated with opioid use, including the development of tolerance and addiction. Oxytrex uses ultra-low-dose naltrexone to counteract the excitatory effects associated with chronic opioid use, such as physical dependence.

Hmm... Providing the naltrexone (opioid receptor antagonist) didn't affect the high, then this could be good. Nice find.