Desoxypipradrol

[bhmoab1]

Swim recently recieved a gram of this substance, and is looking forward to working with it, escpacially since mdpv is exceedingly hard to come by nowadays. Just need to wait untill swims new scale arrives since the old one was unfortunatly dropped.

Swim is going to give a sub 5mg dose a go to test for any adverse reactions, and will update on his thoughts about this substance.

[lightmove]

Swim is waiting for a delivery of 100mg of desoxypipradrol. Probably going to try 2 - 3mg as a starter. Does anyone have any experience of using this with other substances at all? Things to avoid or possibly enhance it?

[nanobrain]

^start with 500ug for idiosyncratic testing - 5mg is a whopper of a dose. patience is a virtue.

[rxbandit]

would a pin prick of powder be about 500ug's?

[bhmoab1]

Swim thinks it would be hard to tell you what a pin prick would be, however if you put 5mgs in a 10ml solution you could be pretty certain 1ml would be about right. Swim is not sure if desoxy is soluble in water or not so we can wait for an answer on that one.

swim will be trying between .5 and 1mg tomorow to test for any negative reactions.

has anyone had any allergic reactions to this? If so would oral benydral be adequate?

After that Swim thinks he will go ahead and try 4-5 mgfirst thing in the morning(on a day with nothing to do). Swim is quite the stim fan and thinks from reports that 4-5mgs seems about right. Plenty of xanax is around in case swim is wrong.

Swim loved mdpv and is hoping this one will be as good or better. Swim did like to redose mdpv hourly untill about 100-150mgs were gone in a day or two, but understands redosing on this one might be better left alone.

Those doses for mdpv are in no way a recomendation!

[bhmoab1]

One more thing, have most swims been dosing this one orally? HAve many tried snorting? If so, is there much difference in duration or intensity?

Swim had read that snorting produces a rush, but wants to know if doses shoud be reduced and by how much if this is the path he goes down.

[syntelman]

Yes, orally only. But very tempted trying smoking. Some people over at BL tried this but no final word on duration/dosages as far as I know. Hopefully more people (very carefully of course) experiments with different routes of administration.

[bhmoab1]

yeah swim has seen that people have tried smoking it. swim believes you would need to turn it into freebase for it to be successful.

Swim has also seen at least one member at bluelight reporting snorting and likeing it, however swim could't really ask that member for dose information as it would likely be to high for him.

If any other swims have nasal dosing info it would be apreciated.

After swim finds his oral dose he will give that a go.

[NeonCortex]

Hehe, 1 gram is a lot of this substance! Take it easy with it. And yes, redosing is not recommended at all. At a fairly strong dose that does produces euphoria, you can feel waves of stimulation coming at you many hours after one oral dose. One sure way to get a good feel for the dark side of this substance is to redose when doing larger than small doses. MDPV barely gave SWINC anything enjoyable, but desoxypipradrol does. Do not expect an effect close to speed though, it's different. More like methylphenidate. SWINC believes the explanation to the potency and lack of periferal stimulation is probably the high non-polarity of the compound - it crosses the BBB very efficiently while methylphenidate is much more rapidly metabolized and doesn't cross the BBB as well as desoxypipradrol.

[rxbandit]

swim tried about 2 mg's of this substance this mourning. So far it is very pleasant, and is wondering if their is an adverse effects noted from prolonged usage.

swim will report more once he has seen the full time frame of this dose.

[NeonCortex]

The longer daily consecutive use - the more craziness. Tolerance develops though. Or does SWIY mean prolonged as in redosing indefinitely? That will most likely show to be a crazy idea fairly quickly. If used at therapeutical doses, say 1-3 mgs/day, SWINC don't believe it would cause much of concern short term. But that doesn't mean it can be used as a daily pharmaceutical. Tolerance and build up, remember, the half life is very long and there is a reason desoxypipradrol was dumped once upon a time under the preference of methylphenidate.

[rxbandit]

Alright, my cat went on an unintentionally binge due to time constraint issues. He has to say this compound has a fairly high addiciton potential in his eyes, as he craved it while he was crashing and is still craving it a bit after a week of abstinence.

It appears low doses have both recreational and practical value. The euphoria and speediness is far greater then that of methylphenidate. The duration is fairly reasonable when 1-5 mg's is taken with sleep possible around the 7th hour. All in all a wonderful compound with pleasant applications. just watch out for a habit creeping up with this one.

Also great for doing things that require precision when one would otherwise be tired. swim was falling asleep on a 4 hour motorcycle trip, took about 3 mg's and almost instantly was wired and wide eyed.

Not nearly as overwhelming and intimadating as swim though.

A+ as far as stims go.

[spacehippi13]

swim and swim'z partner snorted it and haven't even considered smoking or ingesting it orally.

to the person that asked for more info regarding snorting, please see my post on page one of this thread.

swim has since done pippy twice more in smaller doses with none of the potential side effects mentioned in the page one post--so definitely smaller is better in that regard--remember, more can always be done if 5mg isn't enough (which was swim's 1st dosage and only lasted a few hours so a redose of approx 10mg was snorted and that's when it got a bit weird and some of the side effects set in for a few hours, then went away, but the benefit was being nicely wired and chatty as hell. lol--great road trip drug!) the total length of the 10mg dosage was about 18 hours or so.

swim said that it has a cold ring to it in the nose for a few seconds-1 minute after snorting (as opposed to the hot burn of crystal meth, which lasts approximated the same amount of time after snorting.) the effects of pippy were felt within a few minits after snorting, same as meth)

swim recommends snorting pippy.

happi day!

[syntelman]

Not nearly as overwhelming and intimadating as swim though.

Yeah, the "desoxy-scare" is very exaggerated IMO. Personally haven't had time to experiment anymore, but at the moment I am very interested in alternative ROA's such as smoking to see what it does to the rush/duration. If anyone tried smoking either the salt form or the freebase please post your experiences!

[NeonCortex]

From what SWINC has heard, combining with psychedelics is not recommended.

[spacehippi13]

Swim totatly agrees!!! Swim and partner both combined pippy with LSD and it was a BAD thing. It was at a festival and they both experienced a "willing to throw someone out a window to make it stop" feeling towards the music--thankfully it was at seperate times and one could take care of the other one and rush them into a cave in the most extreme case,(the only place at the festival where the music couldn't be heard) until the crisis moment was over. Pippy & psychedelics = not a good combo boys & girls!......but who knowz....maybe they'll try it again...for the sake of experimentation....silly kids!

[Handle]

Hey, just a thing about piradrol, its derivatives and appetite suppression, here in Australia there is a geriatric restorative on prescription called 'Alertonic'. Well, SWIM and his friends all swigged a bottle between 'em, and then went back to class thinking they were all 'high'. We all realised later it was just imagined, that stuff has NO effect, don't worry about it, I can't see how a stronger version would be any better. The fact of no appetite suppression made it desirable to the makers of alertonic, because it was basically just for depressed and tired old dudes who weren't active or eating much, and so it had a little alcohol, some vits and minerals, and pipradrol all to give them a little pick me up. But they didn't want them to stop eating, so pipradrol was suitable, because it caused slight stimulation but none of the speedy effects. SWIM is sure that a few unpleasant experiences with this stuff [meaning the desoxy version] will see that it never becomes a risk of addicting anyone, just give it a miss. It's obvious why they don't test for it much if at all, because it's just not the sort of thing heads would want.

[bob_arctor]

Handle: just because a chemical has in part a name similar or share some of the structure of another chemical, it doesn't mean that desoxypipradrol is just "a stronger version".

[syntelman]

No, it is a very dangerous and unwise comparision. The chemical difference between ephedrine and methamphetamine is more or less the same difference between pipradrol and desoxypipradrol (in fact desoxyephedrine is an historical name of methamphetamine). And all 4 are _very_ different drugs with little relation to eachother in terms of activity except that all are stimulants. One can not easily predict any relationship/change in activity upon even very simple chemical alterations between drugs like the removal of an hydroxyl group.

And it's quite obvious that drugs like desoxypipradrol are not tested for because it is not a drug that has been (ab)used widely. My bet is that if you ask 1000 people that use drugs, 999 would not even know what desoxypipradrol is (which is probably the best for everyone). It is just not economically feasible or practically possible to test for every possible recreational drug that exists.

[Handle]

O.K., look. I never advocated the use of desoxypipradrol, never said it was safe never said it was desirable, alright? So how is that dangerous?
Nobody can deny that the desoxy is chemically similar to pidradrol, and no one can deny that they both work mainly through norepinephrine, and its absence of dopamine effects seems to be confirmed anecdotally [no euphoria or speedy behaviour], so if its chemically related and they work on the same neurotransmitter, it's not as unpredictable as you make out.
No one can deny that desoxypipradrol is stronger than pipradrol, regardless of whether you strictly define it as a 'version' or not.
It's a good thing that you brought up pseudoephedrine, for several reasons. 1. It's no secret what you said about meth, that's why you can find a pharmaceutical grade brand of it called 'desoxyn', and no one disputes that meth is far far stronger than pseudo. However, meth was used as a decongestant in Vick's once upon a time, and to this day some people use herbal and pill form pseudoephedrine just as much as ephedrine because it too still has some very mild effects like stronger stimulants [it blocks the reuptake of dopamine, and the possibility that it also boosts dopamine release 'cannot be ruled out'] albeit to a lesser extent.
So it can be seen that meth and pseudo share certain of each other's effects, and are all versions of 'amphetamines', and to call such groupings unpredictable is a slight exaggeration. Likewise pipradrol and desoxypipradrol, is it really unwise and dangerous to state that the latter is stronger, and chemically and in terms of the neurotransmitter implicated [norepinephrine] it is a stronger version in that family, just as meth is a very strong version of an amphetamine. I say it's not dangerous and unwise, because much smarter and better educated chemists predict relationships and activity changes on such bases all the time, every day.
Syntelman, as a newbie I commend you for being a donating silver member, but I can't see why you had such a problem with the original post which said:
Don't worry about it, meaning don't bother with it because it doesn't have desirable effects.
I'm sure the negative reports out there should discourage most people from trying it
& Just give it a miss, so how is it dangerous and unwise?
You can't say that they are not chemically related, you can't say they don't work mainly via the same neurotransmitter and that one is stronger than the other and exhibits effects that are not different in quality, despite being of a differetn strength, in the same way that pseudo and meth do actually share several properties, and in some aspects differ mostly in strength, but it's not as if they are completely unrelated to the point that predictions cannot be easily made about the relationship between the two. Not easy for me maybe, but a qualified pharmacologist and some subjective reports such as those here could give a fair idea.
Finally on the subject of testing, you seem to have agreed with me totally. If a drug causes no euphoria and quite a few negative effects, there is a reason it won't catch on to the point that it gets well known, abused widely and tested for.

[syntelman]

What I meant was that it is dangerous to predict (well, not the prediction itself but acting upon it) the activity of a drug based upon it's structural similarity to another drug in general. And I still firmly believe that it is very unwise and unfactual to make such statements that "desoxypipradrol is just a stronger version of pipradrol" (or same comparision between methamphetamine and ephedrine).

I am very sorry if I sounded like a grumpy old man, but I personally believe that a lot of harm and myth-making is generated by such generalizations.

And desoxypipradrols main mode of action is actually dopamine reuptake inhibition (as shown by atleast 1 research paper, don't have the ref handy but it's somewhere in the long desoxy-thread over at Bluelight). Also SWIM find it to cause a very decent amount of euphoria with little to no negative effects except the fact that it has a very long duration. SWIMS who actually have tried desoxypipradrol and did not like it seem to be the minority (but it is a pretty rare drug).

PS. I do not want to sound like a propogator for this drug. IMO it is a drug that should be kept away from the general public and due to the long duration it is a drug that probably is best kept a "secret". DS.

Reputation Comments on this post:

your good work here is appreciated, keep it up

[rxbandit]

Swim thinks this chemical has a good deal of euphoria. this is a subjective report but I also think it proves that every other opinion that it is not euphoric is also subjective. There has been little research on this in regards to abuse potential.

also desoxy pipradrol in swims experience does not have that long of a duration if a reasonable dose is take, say around 1.5 to 2 Mg's. swim has only suffered negative side effects when he has re dosed. I think its never safe to make sweeping generalizations unless you can back them up. Things can support your hypothesis or opinion but its hard to definitively prove it.

[NeonCortex]

J. Pharm. Exp. Ther.; 1979, Vol. 210, No. 3, 422-428

The IC50 values are fairly equal on both DA and NE.

Predictions can be made from structure, but it is up to real in vitro and in vivo experiments to determine if the predictions were correct. One of the major aspects differing ephedrine and amphetamine, concerning the -OH, is the ability to cross the blood/brain barrier, BTW.

[Handle]

Hey, I would just like to thank you all for trying to explain it all to people like me, really. I guess you're right, like, you know, you're only being circumspect about what you say, I respect that. I really can see your original note of caution for what it was. It's easy for newbies like me to just ramble on with a lot of stuff, especially just assuming which neurotransmitters were involved [something I never bothered to check because I was so intent on being right!] based on a couple of subjective personal reports. Thanks for pointing out some of the actual facts to me.
This really is a good forum.

[fatal]

swim has heard reports from some lab technicians that desoxypipradrol may cause several adverse effects including over stimulation, visual hallucinations, and a very nasty withdrawal/comedown which includes a precipitous drop in blood pressure leading to several other symptoms as a result of said drop. one associate of swim said the reactions his testing had shown indicated that this compound may indeed be fairly dangerous and is probably not for you. take it to mean what you will... this compound is of little consequence to swim but he felt it necessary to pass on this information to us all...