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  #1  
Old 12-04-2007, 19:34
addicted2hc addicted2hc is offline
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Best Way to Potentiate Hydrocodone - Urgent

What are the ingredients and methods society uses to potentiate these opiates and in what order? A quick response would be greatly appreciated.

P.S. I did a search but found nothing that was a clear step by step. it was all just BLAH.
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Old 12-04-2007, 20:00
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Re: Best Way to Potentiate Hydrocodone - Urgent

Source: Antihistamine Aficionado Magazine
Date: July 2000


g equipment and keep some kind of record so there is no uncertainty about dosage.

Reports have circulated about a method for obtaining a smokable freebase form of codeine, but this has not been verified. Snorting powdered codeine is assumed to be ineffective for metabolic reasons. The above-listed methods are theoretically workable for hydromorphone (Dilaudid) and oxymorphone (Numorphan) to an equal or greater extent.

3. The orally effective narcotics have much in common with alcohol as far as absorption goes, and the following methods have been demonstrated to have at least some effectiveness in getting the drug into the system more quickly:
a. Mixing cough syrup or solutions of drug with carbonated beverages
b. Mixing cough syrup or solutions of drug with Gatorade
c. Mixing cough syrup or solutions of drug with warm brandy
d. Using one form or another of the opiate to fortify an over-the-counter cough syrup
e. Preparing a sodium bicarbonate solution or capsule containing the drug
f. Dissolving/mixing the drug in soup or chocolate pudding
g. Mixing codeine cough syrup or liquid into tonic water

4. Mixing liquid forms of the narcotics with antacids or sodium bicarbonate solution has proved to be effective at lengthening the high, although taking them separately has the same effect. There are bound to be tactical reasons for doing it this way -- for example, there are places where a bottle of Maalox is OK but a big bottle of cough syrup with a roman numeral five inside a C or a bottle of pills would raise suspicion.

5. Only so much codeine can be metabolised at one time - if you get above 400 mg, you are wasting it. This does not apply to hydrocodone, morphine, or the other natural or semi-synthetic opiates.

hope this helps you out,and was a quick enuff reply!
  #3  
Old 18-04-2007, 03:37
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Re: Best Way to Potentiate Hydrocodone - Urgent

Just Swim's experience. In the metabolism of hydrocodone it can be N-demethylated to an inactive compound or o-demethylated into hydromorphone which is quite a bit more potent. Erythromycin is a potent cyp3a4 inhibitor (the enzyme that n-demethylates), so theoretically this should shunt the metabolism to the o-demethylation route resulting in more hydromorphone, and well, buzz. SWIM never would of believed it but 2 333mg erythromycin tabs about 2 hours before 100 mg of hydro had SWIM nodding like it was 3-4 bags of GOOD H. SWIM has never been so fucked up on ANYTHING as that combo (this was after 2 months of abstinence but even then 100 mg hydro would normally do jackshit). Someone might consider it if it's laying around. Swim is looking for a place to buy antibiotics now! :P

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