Drug info - Propylhexedrine Basics, Part 2...

[Nicaine]

...continuation of thread, Propylhexedrine Basics -- as long as it's OK with the mods, IMO the previous thread was just getting too long to keep track of.

Reputation Comments on this post:

	wow... all i can say is, "I'm SPEECHLESS!" looks almost too simple...tempting would be an understatement!
	thanks for the write up!

[Micklemouse]

Fine by me Nic'! At 12 pages it's a monster! I'm in the process of trimming it at the mo', so when (if!) that gets finished, I may merge them. Meanwhile...

[Nicaine]

Glad to hear I did the right thing.

BTW, SWIM had a *great* propylhexedrine experience last night. He suspects it turned out so well (vs. the utter sh*t of the last few) for the following reasons:

(1) Only one inhaler was used, and it was extracted rather than the cotton swallowed. SWIM plugged some of it, ate some and snorted some (dissolved in h2o). The dose was kept low enough to avoid some side effects, but high enough to still enjoy. Removing the menthol was a massive benefit, and SWIM will be doing this from now on.

(2) SWIM did not take enalapril last night. He thinks this has been giving him probs with symptomatic hypotension (low blood pressue) once the propyl wears off, as well as lord knows what other side effects. For all he knows, it could be screwing his comedowns worse than the propylhexedrine, causing headaches and heart palpitations.

(3) SWIM is out of kratom, and it wasn't really in his system when he started using the propyl.

(4) SWIM *did* take benzos (clonazepam) this time, which he has hardly been taking at all the past few months. This likely had the biggest impact and resulted in a very chill (almost drowsy) high with no edginess but decent euphoria & sexual stimulation. And it lasted just the right amount of time. SWIM is out of kratom until tomorrow, so he's not quite done hitting the benzos yet... he's got kratom withdrawal to deal with.

Hopefully after such a positive experience he won't be tempted to head out & pick up another Benzedrex inhaler this morning (when his kratom runs out, all bets seem to be off). He's got 5 inhalers on order from a cheap Internet pharmacy, so it would be a waste at this point to pay full price.

[Micklemouse]

Pardon my ignorance here, but would PPX be classed as a phenethylamine? I keep staring at the monster that is Part 1 & the only way forward I can see is to split it into experience & extraction, moving the extraction to the chemistry forum (Phen's?). Thoughts?

[Bajeda]

That could work, but I think you'd want to clearly link the two together to maintain some cohesion.

[EuPhOrIa89]

Acute poisoning by propylhexedrine.....thought Swim would share this with everyone....not a doc but thought maybe someone could get some out of it
http://www.pubmedcentral.nih.gov/pag...29&pageindex=1

Reputation Comments on this post:

interesting article

[Nicaine]

Originally Posted by EuPhOrIa89

Acute poisoning by propylhexedrine.....thought Swim would share this with everyone....not a doc but thought maybe someone could get some out of it
http://www.pubmedcentral.nih.gov/pag...29&pageindex=1

The title's a bit strange... doesn't sound like poisoning, sounds like he had a heart attack. Nobody should assume PPX is "safe" because it's sold over the counter, by the way... it's pretty potent sh*t. Amphetamines can cause sh*t like this, and so can propylhexedrine.

[monkeygone2heaven]

Originally Posted by EuPhOrIa89

Acute poisoning by propylhexedrine.....thought Swim would share this with everyone....not a doc but thought maybe someone could get some out of it
http://www.pubmedcentral.nih.gov/pag...29&pageindex=1

that's very interesting. and a bit scary!!

swim takes proply sometimes. she's taken between 1/2 - 2 inhalers per day so far. swim would recommend starting small as with any substance.

[EuPhOrIa89]

^^is it worth trying though?? swim really wants to try it but has little experience to stimulants except for coke and adderall. If swim does take it...should swim start with half of the cotton first just to see how he reacts? thanks in advance

Reputation Comments on this post:

Good posts and use of swim

[Nicaine]

Originally Posted by EuPhOrIa89

^^is it worth trying though?? swim really wants to try it but has little experience to stimulants except for coke and adderall. If swim does take it...should swim start with half of the cotton first just to see how he reacts? thanks in advance

Only SWIY can decide whether it's worth trying... it's really a silly question to ask of others. SWIY should read the experience reports and draw their own conclusions.

Re: half the cotton -- yes, that's what SWIM recommends. Or even 1/4 to really play it safe. It's rare someone has an extreme reaction as in the aforementioned "poisoning" article, but relatively common to experience nausea and headaches. SWIY should take this into account in deciding whether it's worth trying or not.

Lately SWIM has been thinking the "hangover" he gets in the 24 hrs. following use is not worth it anymore, and he's considering never using propyl again. In many ways it's even worse than a bad alcohol hangover.

[Ranke]

Originally Posted by Nicaine

Do not attempt snorting dried crystals directly, unless your nose is made of stainless steel .

lol swim tried this and didn't have much trouble with it, but after snorting 10mg of 2c-e anything but bupropion is nothing. 2c-e is by far the most painful thing swim has ever snorted, bupropion comes in second with long lasting swelling + pain. But back on topic swim just wants to point out that nicaine is correct in that PPX is not distributed evenly in the inhaler. If swiy looks at the cotton it has a yellowish oily spot in near the center that swim suspects is where a mix of PPX and various oils has been squirted. Oh and the nasel PPX seemed to work reasonably well despite the fact that swim burned it a bit.

P.S.
Thanks Nicaine for all the info and reports on PPX, maybe one of these days we will be discussing new cyclohexyl analogs of psychedelic and dopaminergic PPA's. Swim is fairly confident that withen a year he will have enough glassware and the space to begin his research .

[Micklemouse]

Please continue any hypothetical Propylhexedrine extraction discussion in Propylhexedrine Chemistry & Extraction. If anyone finds any stray posts in the original Propylhexedrine Basics thread, please pm me with links & I will add them.

[Paracelsus]

Since recreational use of propylhexedrine isn't very well documented, I think it would be a good idea for somebody interested to write an article about it. This way all information from the huge amount of post material on this forum can be compiled and much easier to access. Info about writing articles can be found here.

[svenghali]

SWIM's friends asked him tonight whether or not it would be a terrible idea to take a low dose of this with DXM tonight. He said that perhaps they should wait with the propyl, as he feared they might drop dead of aneurysms or heart attacks. What are all of your SWIM's opinions?

[Ranke]

Swims suggests swiy waits. Swiy won't appriciate the effects of the propyl with the dxm and it will probably ruin the dxm. Wail till tomorrow and you will get a little stacking effect from dxm after glow and the propyl.

[Nagognog2]

Never, never, NEVER mix DXM with other stimulants. It's begging for a heart-attack or stroke!

[Ranke]

Originally Posted by Nagognog2

Never, never, NEVER mix DXM with other stimulants. It's begging for a heart-attack or stroke!

Nag what would be the chemical basis for this? Swim has never had any increase in heart rate from dxm. Neurochemically it works primarily as a NMDA antagonist, nicotinic antagonist, SSRI, and sigma 1 & 2 agonist. None of these seem to have much potential for problems other than possible serotonin syndrome if one was to consume extremely large quantities of propylhexedrine. I only ask because swim has mixed small amounts of 2c-e and d,l amphetamine (not at the same time) with dxm and noticed no heart issues. In both cases it was roughly 5mg.

P.S.
Don't take this as advocating the taking of stimulents with dxm. Doing so is dangerous and for the most part pointless. If swiy does this they are gambling with their life.

[Hollow Hippie]

Originally Posted by Ranke

Nag what would be the chemical basis for this? Swim has never had any increase in heart rate from dxm. Neurochemically it works primarily as a NMDA antagonist, nicotinic antagonist, SSRI, and sigma 1 & 2 agonist.

Dextromethorphan is not an SSRI, it is an agonist of serotonin.

[svenghali]

Yeah, SWIM ended up telling his friends to chill on the propyl, he decided he'd rather not have a bunch of dead bodies lying around.

[seanman05]

Swim would like to try this again, but he is somewhat afraid. Last time swim took this he absolutely loved it, only problem is he had a TERRIBLE comedown. He couldn't sleep up till like some 30 hours later. He was wide awake the whole night. Could it have something to do with what he did during the day. He had an energy drink at lunch, which was about 5 or 6 hours after he took the propyl, his douchebag coach also made him sprint A LOT that day when he usually does nothing, which was about 7 or 8 hours after he took it. He was also experiencing those unpleasant burps for like 24 hours straight, maybe because he didn't eat much during the day? He said they made him not hungry. Regardless, he would like to try it again, only this time be able to fall asleep that night and not have a terrible comedown. If he took the propyl, along with maybe some ibuprofen and diphenhydramine that night to sleep, would he have a bad comedown?

BTW- When swim did this he only took half of a cotton rod, so roughly 125 mgs.

[radiometer]

^ Propylhexedrine, energy drink, and sprints? That sounds like a recipe for cardiac arrest.

[seanman05]

Yeah, it was terrible. Swim never runs at practice because he usually blows it off, but this time swim's coach was a bitch. The energy drink was just a stupid idea.

So with no sprinting and energy drink, would swim have a bad comedown and not be able to sleep?

[seanman05]

Anyone? Swim needs to know that if he takes propyl again without running and energy drinks, will he have a terrible crash? What can swim do to avoid this crash and just fall asleep later that night?

[Micklemouse]

The lack of excess strain on the heart will probably help! Please also review Propylhexedrine Basics & Propylhexedrine Experiences for more insight

[seanman05]

Swim plans on taking the propyl along with some ibuprofen to prevent head pain. He is also thinking about taking maybe some valerian or diphenhydramine that night along with maybe some more ibuprofen in order to sleep and prevent the dreaded crash. Do you think this would work? Swim is trying to prevent the crash by all means necessary and actually be able to function the next day.