recently mixed a couple loperamide
tablets with water, then added one drop of isopropyl alcohol
to help extract and disperse the loperamide throughout the solution. He would have used grain alcohol if he'd had it, but one drop of isopropyl is not enough to cause any harm. He then added this to a nasal spray bottle and snorted it.
Very minor effects, if any... SWIM is still not sure whether it's placebo or not, but he thinks it is. Stuff that doesn't cross the BBB doesn't have any CNS effects, period, end of story. Sorry guys, sort of a biological law of nature.
I'm unconvinced as well of the notion that snorting
bypasses the BBB; maybe a little bit of substance could end up in cerebrospinal fluid or brain tissues, but probably not much. Perhaps a little bit getting through could help with severe opiate
withdrawal, but one thing SWIM can say for sure: loperamide has no recreational value, none, zilch, zero
. If SWIM felt anything, he can confidently say that 7-8 grams of kratom
has perhaps a hundred times more CNS potency.
SWIM loves the idea of a legal OTC opiate probably even more than most, and the notion of getting something over on the DEA is irresistable... unfortunately, with Loperamide there's just no "there" there.