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Deleriant antihistamines Diphenhydramine, cyclizine and other antihistamines.

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  #1  
Old 14-11-2004, 04:36
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The Diphenhydramine Experience Thread: Please Post Experiences Here

Here is an experience with Diphenhydramine that will hopefully
encourage people to never try it. Around 8 years ago, my friend
took around 6 benadryl pills and aroun 300 mg of DXM. He had the
some very realistic hallucinations. The first visuals he started
to see was a clear wavy lines on the wall. Sort of like the look
of the Predator when he was supposed to be invisible. Next thing
he knows he was talking to his girlfriend for over an hour. After
he returned from the bathroom he realized that his girlfriend was never
there. He continued to see and talk to people that weren't
actually there for several hours. After going to sleep, he woke
up serveral hours later, preceded to the bathroom, did his business,
and then went to sleep on the floor of the bathroom thinking that it
was his bed. During some time between then and the morning, he
managed to remove one shoe and throw it into the living room and also
managed to remove the bathroom door off it's hinges. He woke up
around 10 a.m. the following morning having no clue of what happened
the following night. Throughout the rest of the day, he continued
to see movement out of the corner of his eye, but when he turned to
look nothing was there. Just wanted to share my friends
experience.
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  #2  
Old 14-11-2004, 05:02
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yea i dunno y u want to do Diphenhydramine...i remeber it was in these sleeping pills i had, so i took a bunch becuase did a lot of speed that day and wanted to sleep...well i never got to sleep becuase the whole night all i could hear were people talking and no one else was home in my house
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Old 14-11-2004, 06:46
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i have had some pretty messed up experiences with them. i have taken doses up to 550mg of it.


i don't really like the drug, i have done it about5 times and only one of them was any good. mostly it is just insane amounts of tiredness. i always got a general feeling that something is missing. i felt very dirty and things just couldn't be right. i had some weird hallucinations. big black dog heads came out of my computer screen, and i saw a huge moth on my blanket. there were many other ones too. it's a creepy drug, and not really worth it.
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Old 18-07-2005, 05:18
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The Diphenhydramine Experience Thread: Please Post Experiences Here

Diphenhydramine is like that drunk cousin that you hate at your
reunion, you know, the one that reminds you of Ambien and Benzo, but
well, he's too dumb and shitfaced.



Dosage: 12 x 25 mg (250 mg)



So this is swallowed all at once, no time interval. Erowid qualifies the following dosages:

-Threshhold 10 mg

-Light 25-150

-Common 150-300

-Strong 250-300

-Heavy 400-700

-Lethal (with rats)500 mg



I would definitely never go over a dosage of 300 mg. I mean,
what's the point? You can only feel so drunk, and this is not a
drug that will enlighten you or provide you with spiritual
experiences. The most I've ever done is 275 mg. This is as
follows.



Diphenhydramine was bought at pharmacy. It is a OTC found in some
allergy medicines (mainly the infamous Benadryl) and also sleep
meds. I've only used sleep meds, they have less inactive
ingredients. Just try to find one with only diphenhydramine
listed as the only active ingredient. 12 of the 25 mg pills were
swallowed on empty stomach, effects were noted within exactly one
hour. I have no idea why, but they always exactly kick in one
hour later. Almost to the dot.



Anyway, overdosing on these pills will give you a drunken sense.
This is a purely physical drug. You will feel very sleepu, almost
as if your muscles were in some kind of cement or quicksand. Your
mind will slow down. Everything will slow down. You will
try to stay awake, and it will be very hard. This is the fun
part; you fighting the sleep. You can try caffeine pills or
energy drinks.



It is my theory that this fighting your desire to sleep creates the
"diphenhydramine feeling." It is hard to describe.
Basically, the closest I can come is to ask you to remember what it is
like when you are in your bed, trying to fall asleep. You know
that period when you realize that you are falling asleep? That
usually only lasts a few seconds, because you are soon asleep.
With diphenhydramine, that feeling is prolonged as long as you stay
awake.



I have never lasted more than 2 hours before I fall asleep.



I have also attempted this once during the day, and the effects were
greatly diminshed, leading me to think that it works much better in the
dark. So stow all the breakable things in your room away, close
the door, put on some heavy beats, and lie on the ground until the drug
kicks in. Then try to stand up.



That is the diphenhydramine feeling.



Please be safe when you do this, I don't know if it is illegal to
overdose on these whatever, I'm assuming all of this info is
legal. Just remember this is a crappy drug. It really
is. There are much better things out there, this is mostly a last
resort/want to try it once. At least in my opinion. Oh, and
you will not want to do anything the next day, you will feel extremely
drowsy (obviously).




Reputation Comments on this post:
  
  never heard so much in depth info on the diphenhydramine buzz... Thanks!
  
  good description of what transpires on this drug
  
  nice report, thanks!
  
  Thanks for sharing.
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  #5  
Old 19-07-2005, 23:33
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Yeah, I took 12 pills last night (btw 12 x 25mg = 300mg) and I had a
very strange body high, I didn't get very tired, and I became quite
nautious... I didn't have any major hallucinations but I saw (or
thought I saw) flashes of color on the outskirts of my field of vision,
mostly in the bottom corners for some reason. Also, I saw a few
black dots flying around or sliding across the wall at different times,
though only out of the corner of my eye.



I will try again, maybe tonight, but I'll smoke a bowl to hopefully calm my stomach.I think I'll go with 425mg.


Edited by: antigenesis
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Old 19-07-2005, 23:40
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http://www.erowid.org/pharms/dimenhy...menhydrinate_f aq.shtml



very useful FAQ on these OTC's. Changed my view on this drug...aparently you can hallucinate on these.




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Old 19-07-2005, 23:57
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What are the physically sensations of this drug? What are the side effects? How do you feel the next day?
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Old 28-09-2008, 00:36
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Re: The Diphenhydramine Experience Thread: Please Post Experiences Here

Quote:
Originally Posted by Alfa View Post
What are the physically sensations of this drug? What are the side effects? How do you feel the next day?
Swim's done enough of this drug, at all doses, and depending on the dose, it varies.
Low Doses-
Physical-worn out, tired and weary.
Side Effects- the physical sensations
Next Day- little hard to get up, but it fades pretty fast.

Medium Doses-
Physical-Slighty euphoric, almost like a Xanax or something along those lines, but less happy.
Side Effects- Drearyness, increased heart rate, but nothing to worry about
Next Day- Tired, almost like a hangover, but without the nausea, possible headache.

Heavy Doses-
Physical - restless, can't get comfortable or sleep, but your head still has a buzz goin' on.
Side effects- Irritability from the physical sensations and hallucinations, plus the ones from the medium doses
Next Day- dont have anything planed. For most of the day you'll just want to chill out and watch a movie or something. Not very sociable, plus if pills are not kept properly you'll get a lot more sick.
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Old 20-07-2005, 01:22
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i have had real weird experiences with diphenhydramine. ive gotten
those very real hallucinations. the trick is to stay awake through the
first drunken stage. this stage is actually quite fun, your motor
skills get all fucked and you feel real heavy. if you dont fall asleep
during this stage you will start tripping about an hour(?) after the
first downer/drunk effects. this trip is not really that fun. ive taken
it maybe about 5 times and i doubt i will do it again. it is by no
means psychedelic, the hallucinations are not kaleidascopic patterns or
trails, they are people and objects that are nearly indistinguishable
from reality. in the heat of this your mind goes to shit. you cannot
hold a thought for more than about 15 seconds. there are very intense
dreamlike states. i remember i was watching "one flew over the cuckoos
nest" on this drug and it was the part where the dude is going crazy
about wanting cigarettes. i really wanted to smoke a cigarette, but i
was afraid to because i thought he would probably ask for one. no joke,
i didnt realize how ridiculous this was until the next day. you will
see people and tlak to them and then realize that they arnet real and
they will dissapear before your eyes. i did a lot of research about
diphenhydramine before i took it so i was prepared for this but i bet
if you didnt know what was coming you would continue talking to
imaginary people for hours. one important point: in the first stage of
drunken heaviness you will want to sleep, but after you start really
tripping you will not be able to sleep for a long ass time. not sure
exactly how long, but several hours. ive always been really out of it
and not been capable of doing sometihng like checking the time when ive
been on it. i had one really shit experience with it that i described
in the "various drugs not covered by other forums" section called "the
dnagers of psychedelic deliriants". all in all its not really a good
recreational drug, but it is weird as fuck, and if you enjoy weirdness
you may enjoy diphenhydramine.

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Old 20-07-2005, 01:55
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polloloco, at what doses did you experience this? I just have
experienced the drunkiness, and then went to sleep because I was tired
and bored. Perhaps I will try this OTC again tonight...haven't
done it in a couple months. I will try to get through the sleepy
part to experience the hallucinations.



What I usually just feel is this super slow down of reality, where you
feel almost drunk in terms of trying to move. Your muscles feel
like they are in quicksand, or underwater, or cement or something,
because at first your mind is still able to move quickly, and then it
succumbs to the chemical as well. At this point you begin to slur
words and such. And all you can really do is think about
sleep. You begin taking small naps, just resting your eyes.
They then get longer, until you say "fuck it" and go to bed.




The next day you will feel very sleepy or drowsy. No hangover or anything, just drowsy.



Hopefully I can bypass this sleepy phase tonight. Will report if
successful. Maybe 400 mg dose of diphenhydrinate as opposed to
300 mg dose of dyphenhydramine. Hopefully this will not effect the 9 hour shift of construction work I have tomorrow.Peace.


Edited by: Diphenhydramine
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Old 20-07-2005, 02:49
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Is diphenhydramine addictive? If so, please describe how and in what way diphenhydramine is addictive. Mentally, physically?
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Old 20-07-2005, 03:16
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300mg (for me)...

Physical sensations:
-Walking is weird - feet feel like they weigh 300lbs
-Really annoying "high" - you can feel the rush in
your head, but it isn't exactly pleasant - feels kinda like someone's
tickling my brain or something.

Side Effects:
-Bad cotton-mouth. Real bad.
-Extreme irratability... just feel like punching anyone who bothers me even slightly.

Next day:
-Really, really tired. Somewhat of a headache.

So yeah, IMO diphenhydramine sucks as far as physical effects... the
interesting hallucinations are what keeps me from giving it a total
thumbs-down. I've seen some of the strangest things on this stuff
- people coming into my house, dogs on the floor, etc. Auditory
hallucinations interesting as well - a lot of whispering and stuff...
only most of the time, you're so out of it that you don't even notice
the auditory. It's like a bad dream or something.

I've heard of people getting mentally addictive to the stuff, and doing
it all the time - like several times a week... I don't think that's
typical though.

Last edited by Phungushead; 23-02-2006 at 10:16. Reason: aesthetics...
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Old 20-07-2005, 03:49
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Yeah, I sincerely doubt this is chemically addictive. Like most
OTC's it has a problem of being "addictive" because it is legal and
extremely easy to purchase, much like dxm can be "addictive" for some
people.



If you like getting fucked up on a regular basis simply because, then this might become habit forming.



Alfa, what led you to believe this might be addictive? And so
many questions from you...hm, interested in trying this are we?


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Old 20-07-2005, 04:11
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Here's some information I found :

Advanced Psychopharmacology
Spring 2005
http://www.humboldt.edu/~morgan/ben3_s05.htm

"Anticholinergic syndrome is the common symptom of
overuse/overdose. Palfai and Jankiewicz relate the description
used among medical professionals to describe the look of drug
action that in interfering with cholinergic systems:

Dry as a bone,
Red as a beet,
Hot as a furnace,
Mad as a hatter,
Blind as a bat.

These extremes should been watched for, especially by
caregivers of children and elderly so that medical attention can
me given. The dry as a bone thing is usually what we want when
using Benadryl. Unfortunately, at the toxic level it can effect
urination and the production of stomach fluids that are
necessary for good physical functioning. The flushed feeling or
look of the dilation of blood vessels and the increased
temperature of the patient can also indicate this syndrome. Mad
as a hatter describes what happens at the toxic level:
delusions, hallucinations, muscle spasms and anxiety. Blind as
a bat, with this drug, relates to the uncommon side effect of
blurred vision. Additional things to look for are constipation,
motor uncoordination and rapid heartbeat. The good news is that
there is effective treatment for this syndrom by using
medications that stimulate cholinergic sites (thus undoing many
of the symptoms).

This ability should in no way encourage overuse/abuse of
benadryl. Although safely used for many, excessive use without
treatment can permanently impair the user and can increase the
chance of seizures or death. Fortunately, this drug has a lower
rate of extended abuse because it does not produce the euphoric
feelings that other medications or drugs can elicit. It is more
commonly abused among young teens or adults who like the
feelings from the sedation effects and have not yet found
"better" highs."

And...

"Side effects/toxicity

Off all antihistamine exposures reported to US poison control
centers in 1999, 7.4% resulted in moderate to major toxicity and
.05% resulted in death. 71% of these fatalities were associated
with Diphenhydramine (2).

Diphenhydramine affects multiple systems in the body. The
mnemonic, dry as a bone, red as a beet, hot as a hare, mad as a
hatter, and blind as a bat, summarizes the classic combination
of central and peripheral anticholinergic effects of
antihistamine poisoning (2).

Some of the most common adverse reactions include:

General: Rash, anaphylactic shock, photosensitivity, excessive
perspiration, chills, dryness of mouth, nose, and throat (4).

Cardiovascular System: Hypotension, headache, palpitations,
tachycardia (4).

Hematologic System: Hemolytic anemia, thrombocytopenia,
agranulocytosis (4).

Nervous System: Sedation, sleepiness, dizziness, disturbed
coordination, fatigue, restlessness, excitation, nervousness,
tremor, irritability, insomnia, euphoria, blurred vision,
diplopia, vertigo, tinnitus, neuritis, and convulsions (4).

GI System: Epigastric distress, anorexia, nausea, vomiting,
diarrhea, constipation (4).

GU System: Urinary frequency, difficult urination, urinary
retention, and early menses (4).

Peripheral manifestations include dry mucous membranes, and hot,
dry, flushed skin resulting from decreased secretions from the
salivary glands, bronchioles, and sweat glands (2).
Vasodilatation occurs in the blood vessels of the face and skin
surfaces. Individuals often appear flushed and warm without
sweat. This, in turn, causes body temperature to rise (2).

When used as a sleep aid, Diphenhydramine has been shown to
reduce REM sleep (9).

Also, tolerance has been shown to develop in as little as one to
two weeks, and rebound insomnia can occur after only one night
of use (9).

Because of their addictive effects, Diphenhydramine
should be avoided or used with caution for patients with
substance abuse tendencies (9).

Seizures are not uncommon and coma occurs in roughly 55% of
reported overdoses (2).

Catatonic stupor and toxic psychosis have also been reported
(2).

Reports of chronic abuse (800 mg. twice a day to achieve
sedation and euphoria) resulted in withdrawal symptoms requiring
hospitalization (2).

Diphenhydramine should be used with caution in persons with
narrow-angle glaucoma, enlarged prostate gland, hyperthyroidism,
cardiovascular disease, hypertension, and asthma (3)."

Last edited by Phungushead; 23-02-2006 at 10:18. Reason: aesthetics...
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Old 21-07-2005, 02:55
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And that's why abusing OTC's can be dangerous and should be taken seriously...



Anyway, onto last night's trip report for diphenhydrinate.



Dose:400 mg diphenhydrinate



+30 mins I start to feel drowsy and so take 200 mg of caffeine via NoDoze.



+40 mins I start to feel that familiar drunken feeling, lying
down. On attempts to stand up, it is hardly felt. So far,
this is exactly like diphenhydramine. And then I hear my name
called. I answer, but no one replies.



+1 hr 20 mins It feels much stronger now, much drunker, muscles have
been effectively cemented in the quicksand feeling. No longer
sleepy. The NoDoze has kicked in.



+1 hr 40 mins My dick suddenly twitches and I freak out, because I
believe there is a cockroach/beetle in my pants moving around in my
crotch, and that my limp dick IS the beetle. I find out by using
my hand that no, there is no beetle, and yes, my dick just randomly
twitched. I also seem to notice this weird physical sensation of
a "light air" being around my body. Yes, I know that makes no
sense, it is like there are less air molecules right near me, as if
there is less air. I start to hear random whisperings, very quiet
in the back of my head, but not enough to freak me out. They seem
normal.



And then sometime later, I think it was maybe 30 mins later, I decided
this was lame, and I needed to go to bed because I had a 9 hr shift of
construction work tomorrow. Was able to sleep, no loss of that
ability.



Aftereffects: The next day I woke up, a little drowsy, but as
soon as I got moving it went away. However, for the rest of the
day, I felt like I had diarrhea, but I couldn't crap for some
reason. I was constipated, but felt like I had diarrhea.
Besides that, normal.



Conclusion: I was a little dissapointed that I experienced no
real hallucinations other than that dick/beetle thing, but hey, perhaps
I just can't get that. Body chemistrys are not all the
same. Maybe I could have stayed up longer, but I decided not to,
it really wasn't worth it and I needed to sleep. On a side not,
this trip report was written in notes, as I experienced feelings.
And I chose not to sit there waiting for feelings to write down, I
tried to distract myself by readin some of the Narnia chronicles (I
think it was The Dawn Treader). Perhaps if I had lain there in
the dark, feelings might have been more intense.



Read into this however you feel, my personal conclusion is that I'll
probably attempt this again in a month or so, when I really have
nothing better to do, and my stash is effectively dead. Like I
already said in a previous post, this is a drug to try if you want to
be a fully experienced psychonaut and are curious about it (because
you're a psychonaut), or are bored and want to fuck yourself up cheaply
because you have nothing else or are too pussy to score real drugs.


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Old 04-08-2005, 11:16
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I tried it once... took half a pack of Benadryl. it first i felt extremely zoned out, then that "drunkenness" kicked in. i felt like i was made of liquid, a really heavy and molten liquid. i felt like every molecule in me was fluid of some kind, and moved in such a way.


There were no real interesting or positive aspects of it for me. i expected the visuals, but didnt get any other than a strange distortion much like that of extreme sleep deprivation. even after fighting off sleep for hours, didnt come to the visual portion of it like i do with dimenhydrinate.


The negatives were basically that i couldnt distinguish whether i was doing things or not. it felt like i had alzheimers or something... i couldget up, walk to get a drink, then sit down... then look at my glass and say "where did this come from?" convinced that i was in my chair the whole time. it was like a dream, and the oddest part was... i have no idea when i went to sleep. it blurs that line very harshly...
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Old 07-08-2005, 00:15
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i took15 last night at tenand man o man was that a wierd experience, i've tried it maybe 4 times bafore. as it began to sink in at eleveni noticed that my depth perception was all screwy, like i kept bumpin into things that i thought i had cleared. i walked outside and saw some shadows on the street pop up into cats and run away very quickly. i instantly went back inside and the drunk feeling set in, my moterskills went down the drain. i stumbled into my room and sat down and went onto this site. i started a topic in the dxm forum and got off the net. i looked at my reflection in my closte door (a big mirror). thats when the creepy realistic hallucinations started. blood in a clown makeup pattern started oozing from my eyes.i shreiked and looked away. i put on the itunes visualizer and began to listen to shpongle. the computerwas putting out the only light in the room, and it was directly on my face. i glanced into the mirror againvery slightly, turning my head as little as possible. in the reflection the eye i could see was pure white, and then my reflection turned towards me and my eyes were glowing white. i felt like my own reflection was trying to hypnotize me. so i went outside again and lay on my lawn and looked at the stars until i fell asleep. i woke up at 6 in the morning and rushed into my room and bundled up into my blankets and fell asleep again. i slept until noon. Edited by: als5555
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Old 16-08-2005, 00:59
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I've taken 550mg of this stuff before, i definently don't recommend going that high. This stuff gives bad cotten mouth, rapid heart beat, and the confused type of hullicinations where you think your taking to someone who isn't around. I've taken this stuff at high doses quite afew times and dramamine which gives pretty much the same affects, but then I realized how much I hated the affect it gives and stoped taking it. After taking it afew times I stoped getting many open eye hallucinations and just mostly would just forget what I'm doing easily. Someone I know has gotten seizures taking this and then smoking weed, so I definently recommend against that.Edited by: Dextro
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Old 01-01-2006, 00:29
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swim took 800mg one time and would rather slit her own throat with a spoon filled with scorpions than take that much again. if you like dxm, dont try it with that because the shit completely overpowers the dxm, and u just wasted cough syrup. its bloody terrifying if you have to go to school on it also, so try it a few times until you vomit and are too scared to take it again.

like me....tee hee hee.

safe tripping!!!!!
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Old 01-02-2006, 05:51
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SWIM acheives this feeling you all talk about not solely with diphenhydramine, but with a combo of a few sedatives.

100-150mg dimenhydrinate (the same as but less potent than diphenhydramine)

1 mug of camomile tea

1 mug of this sleep concauction tea which has camomile, peppermint, lemon balm etc.

followed with 800 mgs of methocarbamol (cns depressant found in robaxacet, robaxil etc.)

This gives him the feelings exactly like that of a high dose of just diphenhydramine. It's not exactly "fun" but he uses it to sleep and relax at night, also if he's trying to avoid drugs for a while, on days where he feels weak this will be enough to keep his head busy. He realises these are still drugs but when he says avoiding drugs he means certain drugs to avoid addiction.
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Old 23-02-2006, 00:53
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SWiM's taken upwards of 300mg a couple of times. It's really not worth it, IMO.

You feel FUCKED UP.... but it's not really a "good" kind of fucked up. It's the kind of fucked up you get when you're really drunk and you wish you weren'ty drunk anymore.

It's a weird, tickly sensation in your brain that you want to escape from but it just can't happen.

The hallucinations are friggin strange. SWiM kept seeing people in his room, lying on the floor. lying on my bed. standing in the corner. It's interesting becase even though he's aware that these people should NOT be in here.... It doesn't seem to bother him. Like he don't care. He'd look up and there would be a tall man standing in front of a closed door. A dark, shadowy figue. He'd turn his head again and he would be gone. These are not like "psycedellic" hallucinations. There's no breathing or wavyness, no loss of depth perception... just INCREDIBLY real things that are actually not there at all.

The auditory stuff is weird, too. He kept hearing LOUD footsteps going back and forth outside in my hallway. VERY realistic. The voices and conversations heard whispered in his head... seemingly from behind the wall were completely indistingushable from reality.

The hallucinations are the only thing that makes SwiM want to do this again. SWiM told me "They're so fucking real it makes you question everything you see around you"

Last edited by Micklemouse; 07-03-2007 at 10:12.
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Old 03-10-2006, 06:03
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How long is the duration (including onset) of a Diphenhydramine trip at a dosage of just below or 300mgs? A couple of hours, the whole night, or just depends? Should SWIM make sure not to plan anything for the day after?
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Old 03-10-2006, 06:12
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Duration seemed to be about 6-8 hours from ingestion to feeling normal enough to perform everyday functions, like interact with sober people. While on the drug theres not much sense of time, so it can be difficult to gauge how long it is lasting. SWIY may have a headache and groggy feeling the next day, so maybe dont plan anything too strenuous, but SWIY won't still be tripping when she wakes up.

Honestly though, read up as much as SWIY can before trying this drug. The "hallucinations" are more like delusions, in that SWIY will not be able to distinguish them from reality. Sounds and sights seem completely real, and swiy will react to things that arent there and assume this is perfectly normal, unlike shrooms, acid, or DXM where there is the tendency to remember that one has taken a drug, and what aspects of one's environment are "real" or not.
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Old 03-10-2006, 06:47
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SWIM has been curious about delerients for a bit and has been reading up on delerients for about a month, and diphenhydramine for a week. She's going to start slow, and never go past the mark where she can't remind herself that "it isn't real". SWIM was just wondering how long it took, and thank you for the quick and informative reply! SWIM is planning on taking 200mgs first to get a feel and then 250-275 mgs for the actual trip about a week later is she feels up to it. SWIM will post the report here..unless he can find a thread labled "diphenhydramine experiences".
Thanks again!
Another thing that SWIM finds interesting is that many people report seeing spiders while on diphenhyramine, and also report seeing clearish gelatin blobs a lot too. What makes certain hallucinations common to a drug? Like why do so many people report seeing children on salvia? SWIM is interesting to hear SWIY's thoughts on the matter, or reports of seeing similar things.

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  an interesting question to pose. cant wait to see what people have to say about this one.
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Old 07-08-2008, 04:55
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Re: The Diphenhydramine Experience Thread: Please Post Experiences Here

this is swims 2nd worst drug expierience (next to dramamine). Swim ate 300 mg of this and after an hour was REALLY tired, the trip sucked was mostly swim feeling retartded. Next day he was tired and felt like his brains function was decreeased 10 percent. Swim has found otc highs suck. Benadryl, dramamine, and dxm all were swims worst durg expierinces.
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