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cocaine and ADD / ADHD
for starters hey to all, first post in the boards, so nice to meet you.
ok, as far as we can tell ADD is probably a result of imbalances in dopamine levels. Untill resently it was hypothesized that a lack of certain dopamine transporters, now there is a concensuse that its not the transporters that have the problem but dopamine it self (being lower).
in any case, it also known that cocaine binds to DAT leaving higher concentrations of dopamine in the synaptic cleft.
What got me thinking is the fact that SWIM has a mild case of ADD (though SWIM is lucky enough to be a rather fast learner, so he can compensate some). When SWIM first tried coke (and then a couple of times more) the net effect was not stimulation, talkativeness, self importance etc. No, it was more a feeling of calm, a little more confidence, and a paradoxical ability of SWIM's brain to shut the fuck up. Everything was clearer and more direct, external stimuly, thought sequences etc.
As a result even 4-5 hefty lines of coke had very little crashing effect, just a feeling of iminent bad news and a general apathy. But other than that nothing else.
The whole thing actually i can say it was a much more pronounced version of the effect that ridalin has on me.
So the question, or statement or whatever is this:
could ADD or physiologicaly decreased levels of dopamine could explaine why some people dont seem to respond the same way as most to cocaine?
Last edited by Benga; 11-09-2007 at 10:55.
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