Drugs-Forum  
Home Wiki Studies Forum Groups Blog Video Images News
Go Back   Drugs Forum > DRUG-FORUMS > GHB
Mark Forums Read
Register Tags

Notices

GHB GHB, GBL and related psychoactive substances

 
Thread Tools
  #1  
Old 19-02-2007, 00:32
psilocybin psilocybin is offline
Newbie
 
Join Date: 01-11-2004
27 y/o Male from United Kingdom
Posts: 48
psilocybin should urgently read the rules & received reputation comments.
Points: 60, Level: 1 Points: 60, Level: 1 Points: 60, Level: 1
Activity: 0.2% Activity: 0.2% Activity: 0.2%
lethal gbl dose?

in swims research into GBL he has been unable to find out this information. SWIM keeps hearing of accidental deaths, and from his experiance with gettin doses wrong this seems plausable. However the limited information he has found has shown a very high dose to be necessary. SWIM likes to be educated as much as possible on substances he uses and is curious to find out
  #2  
Old 19-02-2007, 10:07
Psych0nautPlatinum member Psych0naut is offline
Platinum Member
 
Join Date: 27-02-2006
Male from Netherlands
Posts: 2,286
Psych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline MedlinePsych0naut must mainline Medline
Points: 2,986, Level: 8 Points: 2,986, Level: 8 Points: 2,986, Level: 8
Activity: 0% Activity: 0% Activity: 0%
Re: lethal gbl dose?

According to Erowid 3-4 times the normal dose can be lethal, though most deaths due to GBL are probaply because of people suffocating in their own vomit. SWIM thinks to die from GBL itself one has to take around 5-6 times the normal dose or even higher though he doesn't have any clear info.
  #3  
Old 19-02-2007, 10:41
~lostgurl~ ~lostgurl~ is offline
Platinum Member & Advisor
 
Join Date: 23-12-2004
37 y/o Female from New Zealand
Posts: 3,962
~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum~lostgurl~ is living in mutualistic symbiosis with drugs-forum
Points: 9,030, Level: 13 Points: 9,030, Level: 13 Points: 9,030, Level: 13
Activity: 4.1% Activity: 4.1% Activity: 4.1%
Re: lethal gbl dose?

GHB, GBL and 14B are all non toxic as they are rapidly broken down in the body into harmless carbon dioxide and water.

Do a google search "the demonization of GHB" this document is very accurate with its information from what swim can tell and for GHB it says 40 times the amount needed to induce sleep would be needed to be toxic. If this were true than the toxic dose of GBL would be about 100 mils which is a hell of a lot.

Dr Dean Wards research shows that none of the autopsy reports of suspected GHB overdoses can conclude that GHB alone caused the deaths. There have always been other substances present or a pre existing condition.

"GHB does not suppress the reticular activating center of the brain which controls respiration (unlike drugs like alcohol and Rohypnol). In fact, although GHB slows the respiratory rate, it deepens the respirations, so there is little change in blood oxygen content."

There is also a drug that can be used to rapidly wake a person up from a sleep induced dose of GHB. It is called Physostigmine, it is a drug used to treat myesthenia gravis.

Post Quality Evaluations:
Good point, well presented.
  #4  
Old 19-02-2007, 15:57
MrG MrG is offline
GHB
Moderator
 
Join Date: 22-10-2006
43 y/o Male from Earth
Posts: 3,578
Blog Entries: 3
MrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond repute
Points: 9,138, Level: 13 Points: 9,138, Level: 13 Points: 9,138, Level: 13
Activity: 4.7% Activity: 4.7% Activity: 4.7%
Re: lethal gbl dose?

GBL and GHB related deaths (when actually proved to be true) are usually when the user has combined with another CNS such as alcohol or benzo's.
  #5  
Old 21-02-2007, 00:17
psilocybin psilocybin is offline
Newbie
 
Join Date: 01-11-2004
27 y/o Male from United Kingdom
Posts: 48
psilocybin should urgently read the rules & received reputation comments.
Points: 60, Level: 1 Points: 60, Level: 1 Points: 60, Level: 1
Activity: 0.2% Activity: 0.2% Activity: 0.2%
Re: lethal gbl dose?

hmm yea, swim shouldn't believe what he reads! having seen people 'out' on gbl it does seem like it could kill more easily than that, but from research i guess you are right.. swim often drinks with gbl but it doesn't seem to do any harm, altho you do seem to act far more drunk and memory loss is extreme..
  #6  
Old 01-03-2007, 06:38
garbled garbled is offline
Account Awaiting Email Confirmation.
 
Join Date: 13-04-2006
Male from Switzerland
Posts: 69
garbled is a decent psychonaut.garbled is a decent psychonaut.
Points: 112, Level: 1 Points: 112, Level: 1 Points: 112, Level: 1
Activity: 0% Activity: 0% Activity: 0%
Re: lethal gbl dose?

Quote:
Originally Posted by ~lostgurl~ View Post
There is also a drug that can be used to rapidly wake a person up from a sleep induced dose of GHB. It is called Physostigmine, it is a drug used to treat myesthenia gravis.
That is interesting, first I have heard of Physostigmine.

I am aware of a street level wake-up procedure for those who ingest excessive GHB: the smoke from crystal methamphetamine. For some reason, the stimulant reaction of smoking ice represses the coma-like urge to pass out from excessive GHB intake. Snorting, banging, swallowing the methamphetamine did not produce the same result as the smoke did, since those results are not instantaneous. Non-responsive individuals were force-fed methamphetamine smoke using CPR-like procedures, and resulted in about 85% success rate to push back the loss of consciousness associated with excessive GHB intake.

All in the name of science...
  #7  
Old 01-03-2007, 08:29
Lehendakari Gold member Lehendakari is offline
Gold Member
 
Join Date: 28-02-2006
32 y/o Male from Spain
Posts: 699
Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.
Points: 1,430, Level: 5 Points: 1,430, Level: 5 Points: 1,430, Level: 5
Activity: 0.3% Activity: 0.3% Activity: 0.3%
Re: lethal gbl dose?

SWIM himself overdosed once with 6-7 gr of GHB and let me tell you that alcohol poisoning never felt so horrible. The time he wasn't puking he was trying not to pass out and when he stopped puking he had cramps and small seizures and couldn't sleep at all that night. He felt very bad next day also.

Don't know if there is a lethal dose, but I don't want to imagine what a bigger dose can do to you.
  #8  
Old 01-03-2007, 08:51
MrG MrG is offline
GHB
Moderator
 
Join Date: 22-10-2006
43 y/o Male from Earth
Posts: 3,578
Blog Entries: 3
MrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond repute
Points: 9,138, Level: 13 Points: 9,138, Level: 13 Points: 9,138, Level: 13
Activity: 4.7% Activity: 4.7% Activity: 4.7%
Re: lethal gbl dose?

Strange that SWIY would have had such a bad reaction to 6-7g of GHB considering that clinical Xyrem doses range from 3-9g with no ill-effects.

Maybe SWIY's batch of GHB wasn't pH balanced properly.

http://www.drugs-forum.com/forum/showthread.php?t=26372

This report contains all you need to know about both GHB and GBL toxicity.
  #9  
Old 01-03-2007, 09:05
Nagognog2 Nagognog2 is offline
Banned
 
Join Date: 01-02-2005
Male
Posts: 7,226
Nagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPACNagognog2 must think in IUPAC
Points: 3,186, Level: 8 Points: 3,186, Level: 8 Points: 3,186, Level: 8
Activity: 0% Activity: 0% Activity: 0%
Re: lethal gbl dose?

One way people have died as a result of GBH/L has been to take a nice, warm bath while taking too much. It is an anesthetic, ya know? Out you go - and under the water. Glub! Glub! Glub!
  #10  
Old 01-03-2007, 13:50
Lehendakari Gold member Lehendakari is offline
Gold Member
 
Join Date: 28-02-2006
32 y/o Male from Spain
Posts: 699
Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.Lehendakari really adds to the discussion.
Points: 1,430, Level: 5 Points: 1,430, Level: 5 Points: 1,430, Level: 5
Activity: 0.3% Activity: 0.3% Activity: 0.3%
Re: lethal gbl dose?

Quote:
Originally Posted by MrG View Post
Strange that SWIY would have had such a bad reaction to 6-7g of GHB considering that clinical Xyrem doses range from 3-9g with no ill-effects.

Maybe SWIY's batch of GHB wasn't pH balanced properly.

http://www.drugs-forum.com/forum/showthread.php?t=26372

This report contains all you need to know about both GHB and GBL toxicity.
Let someone with no tolerance try 7 gr on empty stomach and tell me what happens.

SWIM's GHB ph was perfect. He used the same GHB batch on multiple ocassions at lower doses and never had problem.

Don't know if SWIY is experienced but 6 gr is a pretty high dose. I would not recommend anyone take more than 2.5 their first time. Would you give anyone 7 gr of GHB and say: "don't worry is within the clinical dosage range."??

I would not.
  #11  
Old 05-03-2007, 06:46
MrG MrG is offline
GHB
Moderator
 
Join Date: 22-10-2006
43 y/o Male from Earth
Posts: 3,578
Blog Entries: 3
MrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond reputeMrG is a true resource and beyond repute
Points: 9,138, Level: 13 Points: 9,138, Level: 13 Points: 9,138, Level: 13
Activity: 4.7% Activity: 4.7% Activity: 4.7%
Re: lethal gbl dose?

I would never consider giving GHB to anyone as that would be illegal.

As for the dosage, 6-7g is certainly a very high dose and wouldn't be recommended at all for rec use, but if you read the Xyrem cataplexy reports you will see that the clinical dose often needs to be high enough to ensure the patient is "knocked out" and asleep rather than risk it being too low and having them "spaced out" and mobile.

SWIM never takes above 2g in a single shot but instead takes a number of smaller shots (1.2-1.7g) through the evening in order to be able to enjoy the buzz.

I wasn't commenting on your dose as being an acceptable rec amount, I merely commented on your stated dose as being within clinical use measurements.

Share this on:

Tags
drugs-forum, fatal overdose, gamma butyrolactone, gamma-butyrolactone, gbl, gbl dosage, ghb, overdose, xyrem

Thread Tools


Similar Threads
Thread Thread Starter Forum Replies Last Post
Dose - Gbl dose and effects marcobrien GHB 1 27-10-2008 09:53
Health - Lethal dose of Vodka? markdahman Alcohol 7 20-11-2004 22:09

» New Threads
Is it true you can use on top of...
Last post by hunter19877
5 Replies, 138 Views
Please explain again how this...
Last post by RainbowJunkieForever
14 Replies, 414 Views
It's all so fucking hard
Last post by babalooj
46 Replies, 2,042 Views
Supplements/Vitamins and Personal...
Last post by Dawn Godess
2 Replies, 12 Views
should I stay or should I go?
Last post by Dawn Godess
2 Replies, 33 Views
10 days baby!!
Last post by torn2bits
3 Replies, 77 Views
Oxycontin 20mg for Crohn's disease
Last post by echo11
3 Replies, 173 Views
My time to give up Tramadol
Last post by Ricky Bobby
9 Replies, 303 Views
When do you know you should put...
Last post by chrisnolan16
1 Replies, 48 Views
Day one starts right now
Last post by Ricky Bobby
53 Replies, 1,259 Views
» New Wiki Articles

Sitelinks: Information:

All times are GMT +1. The time now is 15:19.


Copyright: SIN Foundation 2003 - 2014, All rights reserved
"Wiki" powered by VaultWiki v3.0.20 PL 1.