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  #1  
Old 30-01-2007, 01:25
Ellis D. Ellis D. is offline
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Snorting methadone

SWIM was wondering if methadone is effective when snorted?

-thanks
  #2  
Old 30-01-2007, 01:51
CrookedEye CrookedEye is offline
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Re: Snorting methadone

Not any more so than when eaten. Methadone doesn't provide a rush, at all, so no point in snorting it..
  #3  
Old 30-01-2007, 02:12
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Re: Snorting methadone

Methadone is only "moderately" soluble in water according to its MSDS, and its oral bioavailability is up to 80%, so it probably wouldnt be much more effective if snorted. 80% bioavailability is pretty darn good for a drug taken orally. SWIM would say that methadone has so much chalky material in the wafers anyway that it would be quite unpleasant to insufflate. Like crookedeye says, its probably best to take it as directed...down the hatch and into the stomach.
  #4  
Old 30-01-2007, 04:29
ZepDoorsFloyd41 ZepDoorsFloyd41 is offline
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Re: Snorting methadone

Methadone seems to have a bunch of fillers and waxes and what not, and when SWIM snorted it, it really stuffed up his nose times 10. It wasn't too fun. SWIY should chew it, or parachute it. Parachuting is where SWIY breaks it up into a fine powder, wraps a thin peice of tissue around it into a small ball, and just swallows that. The thin paper will break open very quickly since its so thin, and then the powder will hit SWIY faster. Same thing as basically chewing it, just less gross.
  #5  
Old 30-01-2007, 05:03
Benzeneringz Benzeneringz is offline
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Re: Snorting methadone

SWIM snorted 10 mg's of methadone one time and it burnt like meth. Effects were just not present. He ended up eating 20 milligrams and felt a significant effect. Snorting methadone doesn't do anything and is a waste of such a bioavailable and wonderous drug.
  #6  
Old 02-02-2007, 04:41
Ellis D. Ellis D. is offline
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Re: Snorting methadone

Thanks mucho gusto for the informacion. You all know your sh**. SWIM is farmiliar with the methadone burn, and snorting arpox. 7.5mg noticed something but of placebo? hard to say... SWIM wanted to get some other opinions so thanks for the in-put.

SWIM and I ( iused to have a script) both happen to agree that that methadeon is just as effective if not much more when taken orally rather than insulfated.

SWIM and I actually notice/d a decent amount of "wellbeing" from methadone, nothing significant to H but still something opiod. Like it's cousins it for swim still has it's blanket of opioid warmth for swim to look forwards too.

Hope everyone is chillin smoothly

-Peace
  #7  
Old 02-02-2007, 05:57
Benzeneringz Benzeneringz is offline
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Re: Snorting methadone

I don't think the 7.5 mgs SWIY insufflated was placebo. I mean, snorting methadone is a waste but that doesn't mean nothing gets absorbed into the bloodstream. It's just that swallowing them will put more into your veins.
  #8  
Old 03-02-2007, 22:19
Gaius315 Gaius315 is offline
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Re: Snorting methadone

SWIM snorts methadone frequently because snorting is part of SWIMs addiction (like holding a cigarette for smokers.) SWIM can't tell a difference between taking and snorting, and snorting burns like hell.
  #9  
Old 10-02-2007, 23:03
Orchid_Suspiria Orchid_Suspiria is offline
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Re: Snorting methadone

Methadone can definitely be snorted and it will have about the same effects as ingesting it orally,however as people have said it will burn and probably make you sneeze thus you will lose alot of the methadone in the process.
  #10  
Old 30-03-2009, 04:33
Griffin Griffin is offline
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Re: Snorting methadone

SWiM thought this was interesting, especially as SWiM thought SWiM was ingesting LESS instead of MORE. Now SWiM is up to 45 mg. and is getting scared as it's been 2 months. SWiM wonders if detoxing will be difficult. SWiM was changed from oxycontin to Methadone for chronic pain and methadone works TOO good in SWiM's opinion and SWiM is scared of it, but the doctor prefers rxing Methadone to other opiates for pain even though the half-life is longer. SWiM told SWim's doctor that Methadone is scary because SWiM is hoping that the injections will work and SWiM will not have to take opiates anymore, but SWiM thinks that once on methadone the brain will need opiates forever or be very depressed. What does SWiY think?

SWiM is new on this forum.

Griffin added 0 Minutes and 36 Seconds later...

Here is the abstract SWiM was mentioning above:

OBJECTIVE: Nasal administration of many opioids demonstrates rapid uptake and fast onset of action. Nasal administration may be an alternative to intravenous and oral administration of methadone and was therefore studied in human volunteers. METHODS: The study was approved by the Institutional Review Board of the University of Washington, Seattle. Eight healthy volunteers (6 men and 2 women) aged 19 to 33 years were enrolled after informed written consent was obtained. Subjects received 10 mg methadone hydrochloride nasally, orally, or intravenously on 3 separate occasions in a crossover design. Nasal methadone (50 mg/mL in aqueous solution) was given as a 100-microL spray in each nostril (Pfeiffer BiDose sprayer). Blood samples for liquid chromatography-mass spectrometry analyses of methadone and the metabolite 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolinium were drawn for up to 96 hours. The methadone effect was measured by noninvasive infrared pupilometry coincident with blood sampling. RESULTS: Nasal uptake of methadone was rapid, with maximum plasma concentrations occurring within 7 minutes. The maximum effects of intravenous, nasal, and oral methadone, on the basis of dark-adapted pupil diameter, were reached in about 15 minutes, 30 minutes, and 2 hours, respectively. The respective durations were 24, 10, and 8 hours. Both nasal and oral bioavailabilities were 0.85. Subjects reported that nasal methadone caused a burning sensation. CONCLUSIONS: Nasal administration of methadone results in rapid absorption and onset of effect and high bioavailability, which was greater than that reported for other nasal opioids, with a similar duration of effect. Nasal administration may be an alternative route of methadone administration; however, improved formulations are desirable to reduce nasal irritation.

Last edited by Griffin; 30-03-2009 at 04:33. Reason: Automerged Doublepost
  #11  
Old 09-10-2009, 05:10
orballa22 orballa22 is offline
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Re: Snorting methadone

do not snort it, swim has done it before and it feels like pop rocks in the nose. not fun and makes swim sneeze like 30 times in a row..
  #12  
Old 09-10-2009, 17:34
EyesOfTheWorld EyesOfTheWorld is offline
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Re: Snorting methadone

Snorting methadone is horrifically painful and SWIY will either puke or sneeze it all out or both. Take it from a guy who has abused every opiate on the fucking planet in almost every possible way. Oh, and there's no increase in high, should swiy manage to keep it down.
  #13  
Old 12-10-2009, 14:12
electros[h]ock_patient electros[h]ock_patient is offline
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Re: Snorting methadone

Quote:
Originally Posted by CrookedEye View Post
Not any more so than when eaten. Methadone doesn't provide a rush, at all, so no point in snorting it..
Sorry, but swim has direct personal experience that challenges the old "methadone doesn't provide a rush, at all" notion (in respect to intravenous use anyway).

Swim understands its good practice to tell people to avoid diversion of methadone for their own safety and what not...especially in the case of insufflation here. It just so happens that Eye has gone one further. Swim would consider drug intake a science with rigid laws, then again, does the metabolic system allow for variation in "different" people, because swim just don't understand the common "misconception".

Any bright people with qualifications, or even those with dubious but distinguished informal backgrounds care to weigh in?
  #14  
Old 12-10-2009, 15:43
Nil by Mouth Nil by Mouth is offline
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Re: Snorting methadone

Can SWIM add that a Friend of a friend smoked (chased) some pure methadone powder and almost over-dosed on it(the ambulance was not called but nearly!)
SWIM may add that while she was a heroin user she was at the early stages of addiction and was still 'dabbling' quite a bit.
  #15  
Old 20-10-2009, 08:21
fro069 fro069 is offline
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Re: Snorting methadone

when swim snorted a done once it was worse than any meth or anything ever swims eyeball felt like it was gonna pop out n swims nose n throat burned like swim snorted salt
  #16  
Old 10-02-2010, 21:22
LegalizeSpiritualDiscovry LegalizeSpiritualDiscovry is offline
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Re: Snorting methadone

Snorting it burns because, as far as I recall, methadone is mixed with pure sand so that you a can't shoot it (at least not the crushed up pills) and snorting it burns and can cause nosebleeds. I've never gotten nosebleeds on it, but I've only snorted up to 15mg at a time. I would usually get my shower running, snort it, and then run in the shower and drink from a glass of water and gargle shower water until it stopped burning, which only took about 5 minutes. Hits you while it's still burning. By the time the burning's gone, you already feel really good.

Back then, I used to do that and then do my thang in the shower, and when you bust a nut, you feel like twice as high afterward.
  #17  
Old 11-02-2010, 16:36
Helene Gold member Helene is offline
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Re: Snorting methadone

Quote:
Originally Posted by LegalizeSpiritualDiscovry View Post
Snorting it burns because, as far as I recall, methadone is mixed with pure sand so that you a can't shoot it (at least not the crushed up pills) and snorting it burns and can cause nosebleeds.
Some methadone tablets do contain silicon dioxide, which I assume is what you mean by "pure sand". This seems to be more the case in the US, rather than in the UK - unsure of the situation in the rest of the world.

Some ingredients lists -

Generic Methadone HCl tablets:
Active ingredient: methadone hydrochloride USP
Inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose and
silicon dioxide.

Physeptone® Methadone tablets:
Active ingredient: methadone hydrochloride
Inactive ingredients: gelatin, glycerol, lactose, maize starch and magnesium stearate.

Dolophine® Methadone tablets:
Active ingredient: methadone hydrochloride
Inactive ingredients: magnesium stearate, microcrystalline cellulose, and starch.

Diskets® Dispersable Methadone Tablets for Oral Suspension ("wafers"):
Active ingredient: methadone hydrochloride
Inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, orange lake color, orange-pineapple flavor, potassium phosphate monobasic, pregelatinized starch, and stearic acid.

Methadose® Dispersible Tablets for Oral Suspension ("wafers"):
Active ingredient: methadone hydrochloride
Inactive ingredients: dibasic calcium phosphate, microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, pregelatinized starch, stearic acid.

Generic Methadone Dispersible Tablets for Oral Suspension - orange flavoured ("wafers"):
Active ingedient: methadone hydrochloride
Inactive ingredients: colloidal silicon dioxide, dibasic calcium phosphate dihydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, stearic acid, orange blend: FD&C yellow #6, FD&C yellow #6 lake, and FD&C yellow #5 lake, orange flavor.

H
  #18  
Old 11-02-2010, 17:00
Los_Daddy_Dollas Los_Daddy_Dollas is offline
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Re: Snorting methadone

Snorting the tablets works just as good as eating but quicker, but it feels like u snorted ammonia!! If your taking just 1 7.5 thats why you didn't feel much cuz, up the dosage and keep the swag on!

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Very dangerous to advice someone with low tolerance to "up the dosage"
  #19  
Old 11-02-2010, 20:27
Helene Gold member Helene is offline
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Re: Snorting methadone

Quote:
Originally Posted by Los_Daddy_Dollas View Post
Snorting the tablets works just as good as eating but quicker, but it feels like u snorted ammonia!! If your taking just 1 7.5 thats why you didn't feel much cuz, up the dosage and keep the swag on!
This is extremely dangerous advice. As little as 20mg of methadone can kill a non-tolerant adult. And there are many reported cases of this happening.

Quote:
Originally Posted by Helene View Post
I feel the need to point out that methadone is an extremely dangerous drug for anyone to take recreationally. If you don't have a (relatively large) opiate habit, seemingly small doses can quite easily kill.

Opiate naive individuals have died from taking less than 25mg of methadone. In most countries, the starting methadone dose for heroin addicts can not exceed 30mg. Some time ago, when someone I know was hitting up near enough an eighth (3.5g) a day of smack, and she (finally) started a script, her starting dose was 30mg. She had been an IV heroin addict for over five years, a user for seven. She's been on a methadone script for almost two years. If she (for whatever reason) ended her current methadone script, and wished to start a new one, these regulations on starting doses would still apply. The reason for this is methadone's ridiculously high potential for fatal overdoses.

There are a few reasons that contribute towards this. To start with, many people hear about addicts taking extremely large doses of methadone daily. It's not uncommon for heroin addicts to take as much as 200mg of methadone per day. The vast majority of recreationally used methadone comes from diverted scripts belonging to addicts. The person selling the methadone may be selling it in a bottle with "200mg per day" stamped on the label. This totally distorts the perceived "standard" dosage, and the would-be recreational user is left with an unrealistic and extremely dangerous idea of what amount is safe to consume.

Methadone has an extraordinarily long half-life, up to 36 hours. This means that 36 hours after taking 20mg, 10mg will still be active in your system. Because of this, someone who overdoses on methadone won't necessarily do so immediately after consuming it. They could lose consciousness many hours later. Additionally, if someone who OD's is given the opiate reversal agent Naloxone by either paramedics or another user, it is very likely that after the short-acting naloxone wears off, the residual methadone in their body will cause them to OD again. As a result of this abnormally long half-life, if taking methadone daily (or even every other day) you must add on all the accumulated previous days' dosages to get a true idea of the amount in your system.

Methadone's effects are also relatively slow to start, this can mislead people into thinking that they haven't taken enough, and so make the potentially fatal decision to consume more.

Then you've gotta think about what recreational drug usage actually entails. It's not like an addict wanting to take methadone in order to end the suffering of withdrawal. This is someone wanting to get wasted. They're gonna be upping the dosage, trying to reach that ideal high. They might be mixing it with other drugs, or alcohol maybe. I don't need to spell out the dangers of this, but I will anyway - mixing any opiates with benzodiazepines, barbiturates or alcohol is a fatal recipe for disaster. But mixing methadone with any of these, well, Russian roulette might be a safer pastime.

Additionally, there's the addiction risk to take into account. In someone I know's opinion, methadone is at least as addictive as heroin. Think about those long half lives - you don't even need to use it daily to get a physical habit. And as far as tolerance is concerned, in her experience you build up a tolerance to the "desirable" effects of methadone far more quickly than you do to heroin. Think about the reasons why methadone is used as a substitute drug - it stays in your system for a long time, so it is only necessary to dose once a day. In fact, it sticks around so long that a stabilised methadone user can get away with missing a day's dose without too many ill effects. Any desirable, narcotic effects are lost after only a few days consecutive use. It binds to the opioid receptors so damn strongly that it manages to pretty much block the effects of any other opiate taken on top.

Then you've got the withdrawals... and fuck me, there isn't much worse than methadone withdrawal. It all comes back to that damned half-life - the stuff just takes a stupidly long time to leave your body. Especially if you have many days accumulated doses, it just lingers on and on, dragging the withdrawal out longer and longer. Doing a rattle off methadone can literally last for weeks. And it can be months before one feels anything approaching "normal".

So, what I'm trying to say is this - please think very hard before messing around with methadone. There are so many other drugs out there to get your kicks off, drugs that are much, much less deadly. Drugs that don't have such a high risk of you slipping into a coma and never waking up. Drugs that don't have so a high addiction potential. Even other opiates, painpills, whatever. Methadone is a very, very dangerous drug when used recreationally, and this fact should not be ignored.
H

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as always, excellent advice regarding methadone usage
  #20  
Old 15-01-2012, 02:34
ebrownieboy ebrownieboy is offline
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Re: Snorting methadone

I need help. I used (snorted) meth for the first time three days ago with a co worker believe or not. I will never do that stuff again. But strange things are happening to my body. First off I feel very very tired; so tired that I just want to go to sleep within minutes or even seconds. I sleep all day and still be sleepy. My equilibrium is off; I think my brain is like fried or something. I'm a analyst and still can do work but I can only focus for so long before I get sleepy and start going dumb. I get dizzy and everyone can see how tired and stressed I look in my face. Someone please help me to understand what is happening to me and will I recover soon? I hope I'm not dying or brain dumb. I will never do that stuff again.
  #21  
Old 23-01-2012, 06:03
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Re: Snorting methadone

Quote:
Originally Posted by ZepDoorsFloyd41 View Post
Methadone seems to have a bunch of fillers and waxes and what not, and when SWIM snorted it, it really stuffed up his nose times 10. It wasn't too fun. SWIY should chew it, or parachute it. Parachuting is where SWIY breaks it up into a fine powder, wraps a thin peice of tissue around it into a small ball, and just swallows that. The thin paper will break open very quickly since its so thin, and then the powder will hit SWIY faster. Same thing as basically chewing it, just less gross.
Parachuting methadone it is pointless because it breaks up immediately when in contact with a fluid and minimal friction.
  #22  
Old 23-01-2012, 07:02
LoveNwar LoveNwar is offline
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Re: Snorting methadone

I was told that anything above 30 mgs is just not a good idea. Is that so? Anyone...

LoveNwar added 2 Minutes and 31 Seconds later...

Quote:
Originally Posted by ebrownieboy View Post
I need help. I used (snorted) meth for the first time three days ago with a co worker believe or not. I will never do that stuff again. But strange things are happening to my body. First off I feel very very tired; so tired that I just want to go to sleep within minutes or even seconds. I sleep all day and still be sleepy. My equilibrium is off; I think my brain is like fried or something. I'm a analyst and still can do work but I can only focus for so long before I get sleepy and start going dumb. I get dizzy and everyone can see how tired and stressed I look in my face. Someone please help me to understand what is happening to me and will I recover soon? I hope I'm not dying or brain dumb. I will never do that stuff again.
With so much cutting shit going around, God knows what you took in, rather than real meth...
You should have felt an energy boost, rather than what you say you felt.

Last edited by LoveNwar; 23-01-2012 at 07:02. Reason: Automerged Doublepost

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