SWIM needs a bit of a mind boost in the following period so he is going to start a Selegiline (L-Deprenyl) regimen. SWIM doesn't want to give up his tripping habits, which include 2C's, that have possibly fatal interactions with selegiline, so SWIM is going to integrate selegiline into his schedule. One week of taking selegiline, two weeks off, in order for his MAO levels to return to normal before the trip.
SWIM's concern though is the possibility of long-term negative consequences from selegiline supplementation. After all it boosts dopamine levels, and it would be atypical if the usual homeostatic mechanisms wouldn't move in to compensate. That could result in dopaminergic downregulation, causing withdrawal symptoms after discontinuing. And given that selegiline is usually taken for long periods of time, there could be long-term consequences as well.
Does anyone have experience with selegiline? Did you have any withdrawal or rebound symptoms after discontinuing? For what periods of time did you take it?
For those who don't know what it is, here are the basics, provided by BLTC:
http://www.selegiline.com/
SWIM has already tried it and it works, from the first day
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25-01-2007, 22:37
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