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by James Ketchum
Published by radiometer 11-01-2007 |
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#1
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
PART II
From that point on, he was regarded as a pariah and he spent the rest of his life believing he had committed a serious crime for which he’d never be forgiven. Then Sidney Gottleib — who was the head of the MK-ULTRA program — died. And in his obituary, it mentioned that he was supervising the administration of LSD to unwitting American citizens. [ed: The CIA also dosed unsuspecting attendants at office parties, as documented in Acid Dreams and elsewhere.] And so the light went on in his head at that point, and Wayne realized, or believed, that that’s probably what happened to him. So a case was eventually brought to court, and I was asked to testify on behalf of Wayne. I spent two-and-a-half days on the witness stand, mostly answering questions from CIA lawyers. Ultimately the outcome was not favorable, unfortunately. The judge didn’t feel convinced, and neither did the Appeals court. The judge said, in effect, “If you can explain this man’s criminal behavior with LSD, then I suppose you could blame anyone’s criminal behavior on LSD.” And this really wasn’t very logical and didn’t fit the facts, but that’s how it ended up. It was a rather unhappy ending to an unhappy story. The Ward RU: A number of your volunteers in the LSD experiments expressed feelings of having had a profound experience. More frequently than not, they expressed a sort of regret in coming down and having the experience end. JK: Yes. We were primarily interested in measuring performance on a systematic basis. But, of course, clinically it was pretty hard to ignore the differences in the responses to LSD that we observed. Some individuals would become very frolicsome and laugh a great deal. Some would become depressed and withdrawn; some became paranoid. Seeing the spectrum of responses in otherwise normal young men was quite interesting. One individual in particular, I believe, actually had a therapeutic experience. He was in a group of four, and we held a televised discussion after the test, and he admitted finally under pressure from his buddies that he had had some unacceptable erotic thoughts about the nurses that he was reluctant to reveal. And they told him that was all right, there’s nothing wrong with that. And when he went back to his unit, I heard indirectly that his personality was different. He became more sociable and outgoing. I have to give LSD some of the credit in that case. RU: Also a frequent response from some of the volunteers was to find the tests just silly and absurd and to just laugh at the things they were asked to do. JK: Yeah, under LSD, they perceived the absurdity of being asked to solve as many arithmetic problems as they could in three minutes. Sometimes they refused to do it all together. But in other cases they did their best, but couldn’t do as well as they did before the drug. I took it once and I had precisely the same difficulty solving arithmetic problems, but I didn’t have any of the wonderful visions and fantasies. I guess because I was thinking of the psychopharmacology of the LSD going through my raphe nucleus and so forth. RU: You took 80 micrograms. It’s a little bit shy of a trip. JK: Yeah. But it was chemically pure, U.S. Army-grade, 99.9 percent… RU: Got any of that stuff left? JK: Well, there was 40 pounds left in my office one day in a big black barrel… RU: Oh yes! Do tell the story of the canister. JK: I was chief of the department at that point. When I came into work one day, I noticed that there was a big, black, sort of oil barrel-type drum in the corner of the room. And no one said anything, or told me anything about it. So after a couple of days, my curiosity overcame me. After everyone had gone home, I opened it up and pulled out a jar. And I looked and saw that it was about 3.41623 kilograms of LSD. And so were the rest of the jars. RU: Drop that baby on Iran and see what happens. JK: But after another couple of days, the barrel was gone! I never heard anything; I never got a receipt for it. The LSD there was probably worth about a billion dollars on the street. And it just stayed there for a few days and went away. SR: Speaking of getting onto the street, I’ve never heard of BZ, I guess it didn’t penetrate the black market? RU: That’s really not the sort of thing people tend to want to take. JK: Well, as I say, it’s similar to atropine or belladonna, which some people have taken for trips, and it’s been used through the ages for ceremonial purposes, for various purposes. RU: I remember Durk Pearson saying it was interesting. JK: It lasts about 72 hours in a dose that is just sufficient to incapacitate someone. It can last longer if you take more, but we kept the doses as low as we could. Delirium is not something that anyone particularly wants to go through. It’s more of a shipment than a trip, I would say. RU: You don’t remember much. It’s probably more fun to watch other people take it. JK: Right. Not too much intelligent insight emerges under its effects. RU: Let’s get back to the purpose of this research. What you were hoping for? JK: I felt I was working on a noble cause because the purpose of this research was to find something that would be an alternative to bombs and bullets. It could also be helpful in reducing civilian casualties, which have increased ever since the Civil War from almost zero percent to the eighty percent now or maybe higher — 90 percent perhaps in Iraq, because you can’t really avoid “collateral damage” if the enemy is going to hide among the civilians. Perhaps it’s a good time to rethink our use of incapacitating agents as a humane alternative. The Russians did very well with this. When the Chechnyan terrorists took over an auditorium filled with attendees at a Moscow concert and held them captive for three days, the Russians brought in an incapacitating agent. It happened to be a morphine derivative of high potency, and they pumped it in through the ceiling and the floor, waited for a while, and then rushed in. And those terrorists did not detonate the bombs they had strapped to their bodies; they did not fire their weapons; they were all down on the floor unconscious, as was most of the audience. They were able to save about 80% of the audience. RU: Do you feel that maybe they could’ve used a better incapacitating agent that would’ve allowed them to save everybody or nearly everybody? JK: No, I don’t think there was anything better they could’ve used. This was a quick-acting drug, which is what it had to be. If they’d used BZ or some drug like that, the effects would have come on too gradually. The terrorists would have had time to figure out what was going on. So this was a knockout effect, and it worked very well. And I credit the Russians for doing this, although they seem to be embarrassed about giving out the details, because in the United States and the rest of the world in general, chemical warfare in any form is a no-no. RU: It’s illegal internationally, isn’t it? JK: A number of treaties were drawn up, the last of which was the chemical warfare convention. And it’s now illegal to use any drug that can either cause death or seriously disturbed behavior. And I think it’s unfortunate that we went in and agreed to this treaty because we’re now in a different kind of war from anything we’ve been in previously. SR: I wonder what effect of LSD would have in either dislodging — or maybe even reinforcing – the beliefs of real serious believers, like fanatical Islamists, for example. JK: Well, LSD was discarded pretty early on as an incapacitating agent when it was realized that it produced highly unpredictable effects and that people could still retain the ability to fire a rifle or push a button on a bomb-release mechanism. So I’m pretty sure LSD would not be used. It would have to be something in the opiate category, like what was used in Moscow; or perhaps one of the rapid-acting belladonna-like drugs. Incidentally, although BZ was adopted briefly and even packed into munitions, as far as I know, it was never used, despite rumors to the contrary. And later on we found rapid-acting compounds in the same category — short-acting, rapid-acting compounds that would’ve worked much better. But by this time, the whole notion of militarizing incapacitating agents had lost its window of opportunity. That’s one reason that all this research was kind of left in file cabinets. RU: We’ve talked about psychedelics, and we’ve talked about deliriants. But what about disassociatives like ketamine and PCP? Do those hold any potential in your opinion, and do you know if they were looked into at all? JK: A little work was done with PCP before my arrival. They had a complication. One individual became psychotic and required hospitalization. And this kind of scared them. In fact, that’s one reason I was asked to go there. So PCP would probably be an unacceptable drug. SR: That’s not an uncommon reaction to PCP, right? Violence… JK: It definitely can produce aggressive and resistant behavior that’s very hard to overcome. RU: The 1970s was a time of great revelation of government crimes, and Edgewood Arsenal and your work got roped into the general attitude in the media towards the establishment, towards the military and so forth. Talk a little bit about how you feel the media misinterpreted your work. JK: It grew out of the Congressional hearings, the most famous of which was the Kennedy hearings. The CIA was investigated. Congress attempted to find out just what they did with LSD in the early 50s. The CIA had destroyed all their records and the people who were still around claimed they couldn’t remember anything. But as a result of that, the army was asked to look at its work with similar agents. The Inspector General held a very comprehensive review, the National Academy of Sciences was asked to do a review of the work with BZ, and although they produced follow-ups finding no harm, somehow in the public mind, the CIA work and the U.S. Army work became interwoven. I believe that’s an unfortunate thing. Another mistake was that the media characterized BZ as a super-hallucinogen, which really is not a good way to describe it. It’s a deliriant, basically — pure and simple. RU: You’ve indicated the effects of some of today’s potential chemical weapons have been exaggerated in the media. You’ve spoken about the potency of VX, for example JK: That’s right. This is in relation to nerve agents. I wasn’t an expert on that — that work was going on next door. But people have been told that a couple of drops of VX on the floor of Macy’s would wipe out the entire customer population. And things of that nature have been represented in programs like 24. (It’s a great series but…). People have a morbid fear of anything chemical, which has been encouraged by the media. Many inaccuracies have been brought out. As a matter of fact, ironically, nerve agents are a good antidote for drugs like BZ, and vice versa. Atropine’s used to treat nerve agent poisoning, and nerve agents can be used to treat atropine or BZ poisoning. We found this out in the lab. Of course anyone who heard that they were going to be treated with a nerve agent for their atropine or BZ poisoning would probably be very unhappy and nervous. But it works very well! RU: So tell people how they can get a hold of this book. It’s an independent publication, with a unique design. It’s almost like a coffee table book. SR: I thought you were going to say, “Tell people how they can get a hold of that black barrel!” RU: Yeah. Where did you hide that black barrel? JK: Here. LINK - http://www.10zenmonkeys.com/2007/01/...mical-warfare/ |
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#2
By
BlueMystic
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
Looks interesting. Thanks for the heads up.
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#3
By
Riconoen {UGC}
on
11-01-2007, 23:54
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
If we used some form of LSD or mushroom spray against the enemy I thinkt he war would be over tommorrow.
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#4
By
Nagognog2
on
12-01-2007, 00:04
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
I'd buy this (expensive) tome for the information on BZ alone*. Thanks for posting this! I've been hunting something like this for a long, long time.
* In fact - I just did! |
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Last edited by Nagognog2; 12-01-2007 at 00:10..
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#5
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
I suspect that there was a fairly short print run for this book, and that it will gain value significantly over time - one reason I bought it.
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#6
By
Nagognog2
on
12-01-2007, 02:31
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
I got an email back thanking me and asking for a review. I'll do it. I want this info out in public - before the Feds start it up again. Using pot-prisoners and other terrorists for experimental subjects.
I think I'll strike up a corrospondence with the author. |
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#7
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
You can listen to the audio of the interview here:
http://www.drugs-forum.com/forum/loc...tid=42&lpage=2 |
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Last edited by ~lostgurl~; 28-07-2007 at 12:29..
Reason: changing to df link
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#8
By
rodent
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
Nice find!
I love reading about the BZ experiments... the potency and duration of effects... it's all fascinating and scary at the same time. At least, according to this read, the army didn't pull the crap that the CIA did though you have to wonder just how "informed" the volunteers really were. I didn't realize Ketchum had any type of relationship with Sasha... interesting. |
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#9
By
Nagognog2
on
16-01-2007, 23:52
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
Note: My copy just arrived - Prioity Mail - in perfect shape. Mailed by the author himself, as well as signed and addressed to me in the front of the book. Nice touch! It's a self-published work with a foreward written by A. Shulgin.
This one is going to be a rare book! |
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#10
By
Alicia
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
^^ swia says enjoy the read Nag
!! She herself has some curiosity with delirants. BZ has always been an interest since she has seen "Jacob's Ladder" she knows its a film, but it mentioned BZ was used on troops during that time at the end of it. She herself has no interest in trying delirants. But loves to read about other peoples experiences, she likes reading about people experiencing belladonna too, the ones that survived that is of there experiences. Swia did wonder if u could use 'set and setting' on PCP she assumed it only made normal run of the mil aggressive people aggressive. Rather then people who have control, but then it was stopped because of those reactions. |
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#11
By
Nagognog2
on
17-01-2007, 00:41
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
I've always had a curiosity regards BZ (quinuclidinyl benzilate). Due, in no small part, to it's secrecy.
PCP is not similar to BZ. BZ, which was developed following research done with the JB series by the CIA, is an anti-cholinergic delieriant. Same class as the alkaloids found in Datura sp. While PCP can truly bend your mind, these drugs create an entirely separate reality. You really are being chased by a minotaur. No doubt about it! |
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#12
By
Demonslayer
on
17-01-2007, 15:45
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Re: Hallucinogenic Weapons: The Other Chemical Warfare (James Ketchum interview)
Quote:
SWIM has at least never had an aggressive thought or wanted to harm a single living creature while under the influence of LSD, shrooms or cannabis. They are for the healing of the nations. They are not weapons, but medicines. That is why it never was possible to implement as a tool for control over others. |
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#13
By
~lostgurl~
on
28-07-2007, 12:25
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The RU Sirius Show - Interview with James Ketchum
![]() A new entry has been added to Drugs Archive Description: The RU Sirius Show - Interview with James Ketchum Show 88: Psychotropic Chemical Warfare James Ketchum, the psychiatrist who was at the center of U.S. military research into BZ, LSD, and other deliriants and hallucinogens as potential incapacating chemical warfare agents, joins The RU Sirius Show to talk about his self-published memoir: “Chemical Warfare: Secrets Almost Forgotten.” To check it out, rate it or add comments, visit The RU Sirius Show - Interview with James Ketchum The comments you make there will appear in the posts below. |
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Last edited by ~lostgurl~; 28-07-2007 at 12:45..
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#14
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Re: Chemical Warfare: Secrets Almost Forgotten
The Counterculture Colonel Posted by CN Staff on July 10,
http://cannabisnews.com/news/24/thread24068.shtml 2008 at 19:39:43 PT By Martin A. Lee Source: North Bay Bohemian Among the notables who spoke at the early evening forum was Dr. Alexander ("Sasha") Shulgin, the Bay Area,based psychochemical genius much beloved among the Burners, who synthesized Ecstasy and 200 other psychoactive drugs, and tested each one on himself during his unique, off-beat career. Sitting on the panel next to Shulgin was an unlikely expositor. Dr. James S. Ketchum, a retired U.S. Army colonel, told the audience, "When Sasha was trying to open minds with chemicals to achieve greater awareness, I was busy trying to subdue people." Ketchum was referring to his work at Edgewood Arsenal, headquarters of the U.S. Army Chemical Corps, in the 1960s, when America's national security strategists were high on the prospect of developing a nonlethal incapacitating agent, a so-called humane weapon, which could knock people out without necessarily killing anyone. Top military officers hyped the notion of "war without death," conjuring visions of aircraft swooping over enemy territory releasing clouds of "madness gas" that would disorient the bad guys and dissolve their will to resist, while U.S. soldiers moved in and took over. Ketchum was into weapons of mass elation, not weapons of mass destruction. He oversaw a secret research program that tested an array of mind-bending drugs on American GIs, including an exceptionally potent form of synthetic marijuana. (Most of these drugs had no medical names, just numbers supplied by the Army.) "Paradoxical as it may seem," Ketchum asserted, "one can use chemical weapons to spare lives, rather than extinguish them." Some of the Burners were perplexed. Was this guy cool or creepy? Shulgin, a critic of chemical mind-meddling by the military, was wary when he first met Ketchum at a 1993 event honoring the 50th anniversary of the discovery of LSD. But Ketchum is not your typical military bulldozer type. An intelligent, gracious man with a disarming sense of humor, in his own way Ketchum has always been a free spirit. He and his wife, Judy, who currently reside in Santa Rosa, became close friends with Sasha and his formidable partner, Ann. They stayed in frequent contact and occasionally socialized together. When the Shulgins invited them to Burning Man, the Ketchums joined the caravan of RVs driving to the desert. "I'm kind of a Sasha worshipper," Ketchum, who reads neuropharmacology textbooks during his leisure hours, confessed. Tall and lanky, the colonel, now 76, is one of the few people who can actually understand what Shulgin, six years his senior, is talking about when he lectures on the molecular subtleties of psychedelic drugs, waving his arms furiously like a mad scientist. Sasha took Ketchum under his wing and welcomed him into the fold. Shulgin wrote the foreword to Ketchum's self-published memoir, Chemical Warfare: Secrets Almost Forgotten (www.forgottensecrets.net), which lifts the veil on the Army's little-known drug experiments and illuminates a hidden chapter of marijuana history. A graduate of Cornell Medical College, Ketchum describes how he was assigned as a staff psychiatrist to Edgewood Arsenal, located 25 miles northeast of Baltimore, in 1961. "There was no doubt in my mind that working in this strange atmosphere was just the sort of thing that would satisfy my appetite for novelty," Ketchum wrote. Soon he became chief of clinical research at the Army's hub for chemical warfare studies. Although the Geneva Convention had banned the use of chemical weapons, Washington never agreed to this provision, and the U.S. government poured money into the search for a nonlethal incapacitant. Red Oil The U.S. Army Chemical Corp's marijuana research began several years before Ketchum joined the team at Edgewood. In 1952, the Shell Development Corporation was contracted by the Army to examine "synthetic cannabis derivatives" for their incapacitating properties. Additional studies into possible military uses of marijuana began two years later at the University of Michigan medical school, where a group of scientists led by Dr. Edward F. Domino, professor of pharmacology, tested a drug called "EA 1476" ,otherwise known as "Red Oil",on dogs and monkeys at the behest of the U.S. Army. Made through a process of chemical extraction and distillation, Red Oil (akin to hash oil) packed a mightier punch than the natural plant. Army scientists found that this concentrated cannabis derivative produced effects unlike anything they had previously seen. "The dog gets a peculiar reaction. He crawls under the table, stays away from the dark, leaps out at imaginary objects and, as far as one can interpret, may be having hallucinations," one report stated. "It would appear even to the untrained observer that this dog is not normal. He suddenly jumps out, even without any stimulus, and barks, and then crawls back under the table." With a larger dose of Red Oil, the reaction was even more pronounced. "These animals lie on their side; you could step on their feet without any response; it is an amazing effect and a reversible phenomenon. It has greatly increased our interest in this compound from the standpoint of future chemical possibilities." In the late 1950s, the Army started testing Red Oil on U.S. soldiers at Edgewood. Some GIs smirked for hours while they were under the influence of EA 1476. When asked to perform routine numbers and spatial reasoning tests, the stoned volunteers couldn't stop laughing. But Red Oil was not an ideal chemical-warfare candidate. For starters, it was a "crude" preparation that contained many components of cannabis besides psychoactive THC. Army scientists surmised that pure THC would weigh much less than Red Oil and would therefore be better suited as a chemical weapon. They were intrigued by the possibility of amplifying the active ingredient of marijuana, tweaking the mother molecule, as it were, to enhance its psychogenic effects. So the Chemical Corps set its sights on developing a synthetic variant of THC that could clobber people without killing them. Enter Harry Pars, a scientist working with Arthur D. Little Inc., based in Cambridge, Mass., one of several pharmaceutical companies that conducted chemical-warfare research for the Army. (Two Army contracts for marijuana-related research were awarded to this firm, covering a 10-year period beginning in 1963.) A frequent visitor to Edgewood, Pars synthesized a new cannabinoid compound, dubbed "EA 2233," which was significantly stronger than Red Oil. At the outset of this project, Pars had sought the advice of Dr. Alexander Shulgin, then a brilliant young chemist employed by Dow Chemical. Shulgin was a veritable fount of information regarding how to reshape psychoactive molecules to create novel mind-altering drugs. Eager to share his arcane expertise, Shulgin gave Pars the idea to tinker with nitrogen analogs of tetrahydrocannabinol (THC). Pars never told Sasha that he was an Army contract employee. A declassified version of Pars' research was published in the Journal of the American Chemical Society (August 1966), in which he thanked Shulgin for "drawing our attention to the synthesis of these nitrogen analogs." The U.S. Army Chemical Corps began clinical testing of EA 2233 on GI volunteers in 1961, the year Ketchum arrived at Edgewood Arsenal. When ingested at dosage levels ranging from 10 to 60 micrograms per kilogram of body weight, EA 2233 lasted up to 30 hours, far longer than the typical marijuana buzz. 'I Just Feel Like Laughing' In an interview videotaped seven hours after he had been given EA 2233, one soldier described feeling numb in his arms and unable to raise them, precluding any possibility that he could defend himself if attacked. "Everything seems comical," he told his interlocutor. Q: How are you? A: Pretty good, I guess. . . . Q: You've got a big grin on your face. A: Yeah. I don't know what I'm grinning about either. Q: Do things seem funny or is that just something you can't help? A: I don't"I don't know. I just'I just feel like laughing. . . . Q: Does the time seem to pass slower or faster or any different than usual? A: No different than usual. Just'just that I mostly lose track of it. I don't know if it's early or late. Q: Do you find yourself doing any daydreaming? A: Yeah. I'm daydreaming all kinds of things. . . . Q: Suppose you have to get up and go to work now. How would you do? A: I don't think I'd even care. Q: Well, suppose the place were on fire? A: It would seem funny. Q: It would seem funny? Do you think you'd have the sense to get up and run out or do you think you'd just enjoy it? A: I don't know. Fire doesn't seem to present any danger to me right now. . . . Everything just seems funny in the Army. Seems like everything somebody says, it sounds a little bit funny. . . . Q: Is it like when you're in a good mood and you can laugh at anything? A: Right. . . . It's like being out with a bunch of people and everybody's laughing. They're just.. Q: Having a ball? A: Yeah. And everything just seems funny. Q: Would you do this again? Take this test again? A: Yeah. Yeah. It wouldn't bother me at all. EA 2233 was actually a mixture of eight stereoisomers of THC. (An isomer is a rearrangement of atoms within a given molecule; a stereoisomer entails different spatial configurations of these atoms.) Eventually, Edgewood scientists would separate the eight stereoisomers and investigate the relative potency of each of them individually in an effort to separate the wheat from the psychoactive chaff and reduce the amount of material needed to get the desired effect for chemical warfare. Only two of the stereoisomers proved to be of interest (the others didn't have much of a knockdown effect). When administered intravenously, low doses of these two synthetic cousins of tetrahydrocannabinol triggered a dramatic drop in blood pressure to the point where test subjects could barely move. Standing up without assistance was impossible. This was construed by cautious Army doctors as a warning sign,a sudden plunge in blood pressure could be dangerous, and human experiments with single THC stereoisomers were suspended. Looking back on these studies, Ketchum wonders whether his colleagues made the right decision. "This hypotensive [blood-pressure-reducing] property, in an otherwise nonlethal compound, might be an ideal way to produce a temporary inability to fight, or do much else, without toxicological danger to life," Ketchum says now. Given the high safety margin of THC, no one has ever died from an overdose, and the likelihood that the stereoisomers would display a similar safety profile, Ketchum believes the Army may have spurned a couple of worthy prospects that were capable of filling the knock-'em-out-but-don't-kill-'em niche in America's chemical-warfare arsenal. As for the two exemplary stereoisomers weaned from EA 2233, Ketchum speculates, "They probably would have been safe in terms of life-sparing activity. . . . But a person who received them would have to lie down. If he tried to stand up and get his weapon, he would feel faint and lightheaded and he'd keel over. Essentially he would be immobilized for any military purpose until the effects wore off." The colonel's assessment: "A safe drug that knocks people down�what more could you ask for?" Volunteers for America With THC isomers on the back burner, the U.S. Army Chemical Corps focused on several other compounds, including LSD, PCP, methylphenidate (Ritalin) and a delirium-inducing ass-kicker known as "BZ" (a belladonna-like substance similar to atropine), all of which were thought to have significant potential as nonlethal incapacitants. By the time the clinical testing program had run its course, 6,700 volunteers experienced some bizarre states of consciousness at Edgewood. Under the influence of powerful mind-altering drugs, some soldiers rode imaginary horses, ate invisible chickens and took showers in full uniform while smoking phantom cigars. One garrulous GI complained that an order of toast smelled "like a French whore." Some of their antics were so over-the-top that Ketchum had to admonish the nurses and other medical personnel not to laugh at the volunteers, even though it was unlikely that the soldiers would remember such incidents once the drugs wore off. Ketchum insists that the staff at Edgewood went to great lengths to ensure the safety of the volunteers. (There was one untoward incident involving a civilian volunteer who flipped out on PCP and required hospitalization, but this happened before Ketchum came on board.) During the 1960s, every soldier exposed to incapacitating agents was carefully screened and prepped beforehand, according to Ketchum, and well treated throughout the experiment. They stayed in special rooms with padded walls, while medical professionals monitored their situation 24/7. Antidotes were available if things got out of hand. "The volunteers performed a patriotic service," Ketchum says. "None, to my knowledge, returned home with a significant injury or illness attributable to chemical exposure," though he admits that "a few former volunteers later claimed that the testing had caused them to suffer from some malady." Such claims, however, are difficult to assess given that so many intervening variables may have contributed to a particular problem. A follow-up study conducted by the Army Inspector General's office and a review panel convened by the National Academy of Sciences found little evidence of serious harm resulting from the Edgewood experiments. But a 1975 Army IG report noted that improper inducements may have been used to recruit volunteers and getting their "informed consent" was somewhat dubious given that scientists had a limited understanding of the short- and long-term impact of some of the compounds tested on the soldiers. Ketchum draws a sharp distinction between clinical research with human subjects under controlled conditions at Edgewood Arsenal and the CIA's reckless experiments on random, unwitting Americans who were given LSD surreptitiously by spooks and prostitutes. "Jim is very certain of his own integrity," says Ken Goffman (aka R.U. Sirius). "There is little doubt in his mind that he was doing the right thing. He felt he was working for a noble cause that would reduce civilian and military casualties." Former editor of the psychedelic tech magazine Mondo 2000, Goffman helped Ketchum edit and polish his book manuscript, which vigorously defends the Edgewood research program. Strange bedfellows, the colonel and the counterculture scribe. Or so it would appear. But these days, Ketchum and Goffman see eye to eye on many issues. Both feel that the alleged dangers of marijuana and LSD have been way overblown. No doubt, LSD could wreak havoc on the toughest, best-trained troops, derailing their thought processes and disorganizing their behavior. When used wisely, however, LSD can be uplifting. Ketchum notes that some soldiers had insightful and rewarding experiences on acid, lending credence to reports from civilian psychiatrists that LSD was a useful therapeutic tool. "I had an interest in psychedelic drugs long before my interest in chemical warfare," Ketchum says. "I was intrigued by the positive aspects of LSD, as well as the incapacitating aspects." Mystery Stash One morning, Ketchum arrived at his office in Edgewood and found "a large, black steel barrel, resembling an oil drum, parked in the corner of the room," he recounts in his book. Overcome by curiosity, he opened the barrel and examined its contents. There were a dozen tightly sealed glass canisters that looked like cookie jars; the labels on the canisters indicated that each contained about three pounds of "EA 1729," the Army's code number for LSD. By the end of the week, the 40 pounds of government acid�enough to intoxicate several hundred million people�vanished as mysteriously as it had appeared. Ketchum still doesn't know who put the LSD in his office or what became of it. But this much is certain: some officers at Edgewood were dipping into the Army's stash for their own personal use. "They took LSD more often than was necessary to appreciate its clinical effects," Ketchum admits. "They must have liked it." The colonel was personally a bit skittish about trying LSD. Eventually, he worked up the courage to experiment on himself. Under the watchful eye of a knowledgeable Edgewood physician, he swallowed a small dose and proceeded to take the same numerical aptitude tests that the regular volunteers were put through to measure their impairment. Constrained by the white-smock laboratory setting, his lone LSD experience was somewhat anticlimactic. "Colors were more vivid and music was more compelling," Ketchum recalls, "but there were no breakthroughs in consciousness, no Timothy Leary stuff." Ketchum also sampled cannabis shortly after he began working for the Chemical Corps. His younger brother turned him on to marijuana, but the first time Ketchum smoked a joint nothing happened. "Later, I read about reverse tolerance. Some people don't get high on marijuana until they use it a few times," Ketchum explains. It wasn't until he went on a paid, two-year leave of absence from Edgewood that he started smoking pot socially. Ketchum had convinced the Surgeon General of the Army that it would be in everyone's best interest if he studied neuroscience at Stanford University. How better to keep abreast of the latest advances in the field? In 1966, he joined a team of postdoctoral researchers mentored by Karl Pribram, a world-renowned expert on the brain and behavior. Ketchum related well with his academic colleagues. "I got together with a few of my friends at Stanford and we had some cheap marijuana, which I smoked, and I got a real effect for the first time," he says. "I liked it. It was very sensuous. But I didn't use it very often. I didn't have any of my own." Ketchum's West Coast hiatus coincided with the emergence of the hippie movement in San Francisco. "I was fascinated with this spectacular development," he gleams. "Luckily, I caught it at its peak." Occasionally, Ketchum took his home movie camera to Haight-Ashbury, the epicenter of hippiedom, and filmed the procession of exotically dressed flower children strutting through the neighborhood high on marijuana and LSD. "I was always interested in drugs, primarily because I've always been interested in how the mind works," he says. "So when this wave of psychedelic users descended upon San Francisco, I thought maybe I'd learn more by going there." Ketchum attended the legendary Be-In in Golden Gate Park in January 1967, sitting cross-legged on the lawn with 20,000 pot-smoking enthusiasts, soaking up the rays and listening to rock music, poetry and antiwar speeches. A few months later, the colonel began working as a volunteer doctor at the Haight-Ashbury Free Clinic, where he treated troubled youth with substance-abuse problems. Life After Edgewood Ketchum returned to Edgewood in 1968, but the mood back at headquarters was not the same as before. Growing opposition to the Vietnam War and public disapproval of the use of napalm and toxic defoliants cast a lengthening shadow over classified research into chemical weapons. When journalists briefly got wind of the Army's ambitious psychochemical warfare program, they scoffed at the notion of making the enemy lay down their arms by turning them on. The colonel saw the writing on the wall. Army brass consented when he asked to be transferred to another base in the early 1970s. By this time, the Chemical Corps had concluded that marijuana-related compounds would not be effective in a battlefield situation, but the testing of other incapacitating agents under field conditions would proceed. And drug companies continued to supply a steady stream of pharmaceutical samples for evaluation by the military. In 1976, Ketchum retired from the Army and embarked upon a new career as a civilian psychiatrist in California. Commissioned by the California Department of Justice, he collaborated on a 1981 study comparing the effects of alcohol and smoked marijuana on driving performance. The results were somewhat surprising. "When combined with alcohol, cannabis produced little additional impairment," he concluded. "While alcohol had an adverse impact on steering, THC affected a driver's ability to estimate time. But the combination of both drugs did not substantially increase the impairment produced by either one alone. . . . In fact, there was an antagonistic effect. Marijuana seemed to offset some of the problems caused by alcohol, and vice versa." Ketchum feels that drug prohibition is bad public policy. "It's the refusal to look at the evidence that keeps pot illegal. They misrepresented marijuana as an evil weed. . . . I've always had a libertarian attitude toward drugs. I believe people should be able to do anything as long as it's not harmful to somebody else." In the years ahead, Ketchum would reach out to medical marijuana trailblazers, prominent psychedelic advocates and drug-policy rebels working inside and outside the system to end prohibition. He joined the National Organization for the Reform of Marijuana Laws and became a member of the Multidisciplinary Association for Psychedelic Studies (MAPS). Founded by Rick Doblin, MAPS has spearheaded the revival of scientific investigations into the therapeutic potential of LSD, ecstasy, psilocybin and ibogaine, while also challenging bureaucratic roadblocks that prevent independent cannabis research in the United States. Col. Ketchum attended fundraising events and wrote letters to potential donors, praising the work of MAPS. During the 1960s, Ketchum supervised thousands of drug experiments, yet he barely scratched the surface of the awesome potential of cannabis and LSD. "Jim is not apologetic for what he did before," Doblin says, "and I don't think he sees it as incongruous with supporting research into the therapeutic aspect of psychedelics. These tools have tremendous power, but he only looked at a narrow slice of it while he was at Edgewood." Today, Ketchum steadfastly maintains that cannabis and LSD are safe drugs compared to many legal substances. This is what the Edgewood experiments and other studies have shown, he contends. Given his status as a retired army officer who had extensive, hands-on experience testing psychoactive compounds, he speaks with a certain authority that most medical and recreational drug users cannot claim. Medical Marijuana After Californians broke ranks from America's drug-war orthodoxy in 1996 and legalized medical marijuana in the Golden State, Ketchum got a recommendation from his family doctor to use cannabis for insomnia. "I have personally found it helpful, especially for sleep," he says. "I've had problems with sleep for a long time." It was at a picnic hosted by the Shulgins that Jim and Judy Ketchum first met Tod Mikuriya, the controversial Berkeley-based physician who has been described as "the father of the medical marijuana movement." One of the prime movers of Proposition 215, the successful med-pot ballot measure, Dr. Mikuriya quickly took a liking to the Ketchums and taught them how to use a vaporizer for inhaling cannabis fumes without tar and smoke. Like Ketchum, Mikuriya was a maverick psychiatrist who once worked for the U.S. government. In 1967, the National Institute of Mental Health (NIMH) recruited Mikuriya to direct its marijuana-research program. One day, after leaving his position at NIMH, he got a phone call from Dr. Van Sim, a cohort of Ketchum's at Edgewood Arsenal. A major figure in the Chemical Corps' secret drug-testing efforts, Sim told Mikuriya of Army studies which indicated that cannabis has valuable therapeutic properties. Sim asserted that marijuana "is probably the most potent anti-epileptic known to medicine." Unfortunately, much of this data remains classified. Army scientists also inadvertently rediscovered the powerful antispasmodic effect of cannabis, a medicinal boon subsequently confirmed by many multiple sclerosis and AIDS patients who smoked marijuana and ate ganja-laced cuisine to ease nerve spasms and painful bouts of peripheral neuropathy. "We weren't looking for benefits," Ketchum concedes. "When I was at Edgewood, I wasn't aware of the medicinal history of cannabis." With Mikuriya tendering introductions, Ketchum befriended some of the leading lights of the '60s counterculture, including Tim Scully, the prodigious underground chemist who manufactured millions of hits of black market LSD (remember Orange Sunshine?) while the colonel was administering hallucinogenic drugs to soldiers at Edgewood. "Jim and his wife visited me at my home in Mendocino County," Scully says. "I enjoyed their company. We found that we shared idealistic beliefs about the potential for good in psychoactive drugs, as well as sharing some wry understanding of the pitfalls, too." As for their divergent paths in the past, Scully remarks, "I don't really see his work as having been in conflict with mine. I believe Jim sincerely hoped to save lives by helping in the development of nonlethal weapons as an alternative to conventional weapons." An incurable iconoclast, the colonel has made common cause with counterculture veterans and anti-prohibition activists. His endorsement of the therapeutic use of marijuana and LSD confers additional credibility on views long championed by his newfound allies. Validation, in this case, goes both ways. Embraced as one of the elders, a peculiar elder to be sure, Ketchum somehow fits right in. "I don't have a problem with being difficult to categorize," he says. Sonoma County writer Martin A. Lee is the author of 'Acid Dreams: The Complete Social History of the LSD,The CIA, the Sixties, and Beyond.' He is writing a social history of marijuana. |
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Last edited by enquirewithin; 14-07-2008 at 03:59..
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