Ms-contin help w/ oxy withdrawals?

[Maximill]

SWIM is currently weening himself off of oxycontin so he can take suboxone. He was told he needed to be down to 1 1/2 80mg pills a day for it to work correctly. SWIM is out of pills and the best he can do is Ms-Contin, 60mg. SWIM is currently taking the recomended dosage of oxycontin and will be switching to suboxone on tuesday. Will these Ms-Contin prevent SWIM from going into withdrawals?

SWIM is not looking to get high anymore, just to get by. Any help will be appreciated by SWIM.

Reputation Comments on this post:

Good answers to problem solving replies!

[Maximill]

Also SWIM is legally taking Both pills. Prescription for pain.

[CrookedEye]

Morphine Sulfate should be sufficient for most withdrawal, but people react differently to various opioid analogues, so pleasure/pain relief is very subjective..

[DrMuffy]

Both oxycodone and morphine are opiates and are derived or semi-derived from papaver somniforum, so they sould be able to combat eachother's with drawel effects. But be careful when combing and try not to get addicted to MS contin in the process, haha.

[Maximill]

Originally Posted by DrMuffy

and try not to get addicted to MS contin in the process, haha.

Haha SWIM thinks that would suck quite a bit. SWIM only has a few, enough to last till tuesday so SWIM shouldnt have to worry. SWIM greatly appreciates all the help and SWIM thinks he found a Gold Mine with this board

[Maximill]

Also, SWIM wonders if there would be a problem combing Ms-contin 30mg (1/2 of a 60mg Ms-contin) And a few IR Oxycodones, 15mg, SWIM has a VERY high opiate tolerance (in SWIM's prime SWIM was snorting about 420 mg of oxycontin at a time)

[DrMuffy]

Originally Posted by Maximill

Also, SWIM wonders if there would be a problem combing Ms-contin 30mg (1/2 of a 60mg Ms-contin) And a few IR Oxycodones, 15mg, SWIM has a VERY high opiate tolerance (in SWIM's prime SWIM was snorting about 420 mg of oxycontin at a time)

Woah, now thats a tolarence! If what SWIY says is true then it should be okay to take the half dose and a few more IRs, just be careful because SWIY's tolerance can change for random reasons, so it could be a whole lot lower by now. Also to save SWIY some money, he might want to read: http://www.drugs-forum.com/forum/showthread.php?t=10884
It is a thread about potentiating opiates, and it would come in handy for SWIY! Also back to the ms-contins, morphine does not have a good oral bioavailability, so like only 30% of SWIY's pill will get into his system, ie 30 mg MS contin=9mg morphine dose. So SWIdr suggests that SWIY looks into rectal administration of this drug because it greatly increases the bioavailibility of the drug, like up to 60-75%. SWIdr has done this with morphine plent of times and has a thread stickied on the opiates forum on the instructions for rectal administration.....yes he knows that most people are uncomfortable with the subject, but it is just another form of administration just like snorting.
PS-SWIdr is glad that SWIYlikes this site and hopes he will become a silver member (totally free just need more posts and rep points.....good luck!

[Forthesevenlakes]

As mentioned above, morphine will help stave off oxycodone withdrawals, but if SWIY is trying to quit opiates, keep in mind that SWIY's tolerance won't drop at all if he simply switches to morphine. Almost all opiates are cross-tolerant, and so SWIY will still end up with withdrawals when the morphine runs out, so please be careful of that fact. If SWIY is trying to quit, then it would be best to taper down on the narcotics and switch to buprenorphine as soon as possible, which seems to be SWIY's plan.

[Maximill]

SWIM wishes his tolerance was not so high but what can SWIM do. SWIM was addicted to vicodin for about 3-4 years. SWIM went to a 30 day in-patient rehab and was clean for 5 months. SWIM thought they could test the limits and started on pills again. SWIM found (Due to stories in rehab, which is why SWIM will never go back, SWIM knows everything about every drug thakns to rehab) that SWIM likes oxycontin much more and the rest is history. SWIM has been on oxy's for about 4 months.

[MrJim]

Originally Posted by Maximill

SWIM is currently weening himself off of oxycontin so he can take suboxone. He was told he needed to be down to 1 1/2 80mg pills a day for it to work correctly. .

In regards to this - Who told you that you need to be down to 120mg of Oxycodone a day? SWIM's understanding is that they can tailor the dosage of suboxone (or methadone) to fit the individual habit.

[Dr.Jones]

Morphine is an opiate, and pretty much all opiates can be replaced with other opiates (provided they are the same in respect to mu kappa delta agonist). It will stop withdrawl.

Suboxone, is not a mu agonist, so its not gonna be squeeky clean going from an oxy habit to a suboxone habit. Only about 3 days of pain, no where near a cold kick, then things will get better.

I would recommend cutting your oxy dosage down as well, esp if your just getting on suboxone. Suboxone's upper dosage limit is at 32mg. Which is enough to hold probaly a 400mg a day oxy habit, but 120mg would be way more comfy.

Oxycontin is a cream dream compared to suboxone tho. Unless you are ruining your life with the pursuit of oxycontin, I'd stay with it. But if oyu are running out of scripts ,scorin on the street, its time to change.

[Forthesevenlakes]

Originally Posted by Dr.Jones

Morphine is an opiate, and pretty much all opiates can be replaced with other opiates (provided they are the same in respect to mu kappa delta agonist). It will stop withdrawl.

Suboxone, is not a mu agonist, so its not gonna be squeeky clean going from an oxy habit to a suboxone habit. Only about 3 days of pain, no where near a cold kick, then things will get better.

I would recommend cutting your oxy dosage down as well, esp if your just getting on suboxone. Suboxone's upper dosage limit is at 32mg. Which is enough to hold probaly a 400mg a day oxy habit, but 120mg would be way more comfy.

Oxycontin is a cream dream compared to suboxone tho. Unless you are ruining your life with the pursuit of oxycontin, I'd stay with it. But if oyu are running out of scripts ,scorin on the street, its time to change.

Buprenorphine actually does work at the mu-opioid receptors, its a partial agonist, according to the sources SWIM has read. Tapering down slowly is usually the best way to go, over the period of months or weeks. Even after that, its possible to have some withdrawals off as little as 0.5 mg buprenorphine, but it wont be anywhere nearly as bad as withdrawing from a large amount of oxycodone.

[Dr.Jones]

I know bupe is listed as a partial mu agonist, and technically it is.
but:

When I say mu agonist, im talking about the more pronuced mu-1,2 effects, the euphoria, the noddin off, the one everyone loves. Bupe binds to the mu, but not the way we want, and has extremly storng antagonist properties, bad for precipiated withdrawl, good for making sure a junkie isn't taking other, more euphric mu agonists.


*the mu isn't just one receptor, its a group of multple, different receptors. As a matter of fact, not too long ago they proved that the opiate receptor responsable for respitory depression, and withdrawl, really are not nessisarly the ones that cause the major euphoria and pain relief. In fact, most all evidence points to that fact. Everyone is too busy trying to make wacky cox 2 inhibitors, like vioox and celebrex, when the ignore opiates due to their stigma. And god, the stigma is halfway appropriate. Halfway. Look, we have a known safe, one of the most used drugs in the history of man, properly dosed and addiction monitered, is a fucking miracle drug.

Gee, think we kinda got something going there? Or should we just scrap and it take a 100% different approach.

There is something really special with 'opiate receptors' (btw the only reason they are called opiate recetpors is because we knew that opiates effected them before anything else)




To all the opiate kids reading this board: no this does not mean you will see or have a chance to abuse an withdrawl-less opiod in your day. Sad times we live in, huh

[brown_chunx]

If only one could control their brain to the point where they could make their opiate receptors create euphoria and pain releif. 'Twould be truly a miraculous ability. and yeah, 420mg of oxy a day is a LOT. Way too expensive for your everyday junkie.

A friend of mine actually died injectiong 2 80s, and his tolerance was monsterously high and he was about 6'5", 400lbs, but 160mg entering the heart all at once is probably too much for most people to handle.

As for the withdrawels, when SWIM has them he's happy to find any opiate. MS, Oxy, vics, percs, t3s, darvocets... Every opiate helps tremendously, but most of them are a LOT weaker than MS/Oxy and heroin. I think that Oxycodone and hydromorphone are the two derivatives of morphine, so MScontins are probably half-strength to oxys.