Codeine Potentiators

[fiveleggedrat]

Please disregard Swim's earlier posts, Quercetin KILLS the codeine experience, and should only be mixed with morphine derived drugs, and not codeine or codeine derived drugs. It made him need about 7 times as much to get high with quercetin in his system.

[darkglobe]

Not sure if the antihistamine gets taken out thru CWE. My hunch says it won't. SWIM recommends SWIY avoide Codeine pills with any other active ingredients, as Diphenhydramine at high doses can cause Delerium.

[RoboCodeine7610]

Diphenhydramine H2O Solubility 1 g/ml No, it won't go away and swim actually thinks that 1g/ml is even more than codeine. Even if you do not remove it diphenhydramine is not dangerous in dosages up to 300 mg but will completely overpower the codeine leaving you with an aticholinergic trip which is quite unpleasent in swim's opinion but that some people apparently enjoy...

[darkglobe]

Doses of upto 300mg are not dangerous?? Maybe not, but a dose this high is not recommended.

300mg is more than enough to cause complete Delerium is some people, especially those with no tolerance.

SWIM recommends only THERAPEUTIC doses of antihistamines with Codeine. In SWIM's opinion consuming Diphenhydramine with Codeine won't add any significant effects (positive, at least) to the Codeine.

Antihistamines can be used at their stated doses to reduce "the itch" associated with high doses of Codeine, but that's about it. In SWIM's opinion, anyway. The use of "Generation 1" antihistamines is recommended (the drowsy type), as prescription non-drowsy antihistamines are known to have some dodgy interactions.

[RoboCodeine7610]

Originally Posted by darkglobe

Doses of upto 300mg are not dangerous?? Maybe not, but a dose this high is not recommended.

300mg is more than enough to cause complete Delerium is some people, especially those with no tolerance.

SWIM recommends only THERAPEUTIC doses of antihistamines with Codeine. In SWIM's opinion consuming Diphenhydramine with Codeine won't add any significant effects (positive, at least) to the Codeine.

Antihistamines can be used at their stated doses to reduce "the itch" associated with high doses of Codeine, but that's about it. In SWIM's opinion, anyway. The use of "Generation 1" antihistamines is recommended (the drowsy type), as prescription non-drowsy antihistamines are known to have some dodgy interactions.

Yeah, swiy's right "not dangerous" was probably the wrong sentence to use.Maybe it would be better to say "not toxic"for most people.SWIM knows only therapeutic dosages of sedative antihistamines are recomended, but swim's point was that the diphenhydramine wouldn't kill him (probably).

Reputation Comments on this post:

reputation abuse

[darkglobe]

Yep. Each individual is different. What could kill one won't hurt another.

[RoboCodeine7610]

SWIM already posted this in another thread but thought this thread was more appropiate:

Nigella sativa seed has opioid action. in a laboratory the seed oil suppressed nociceptive response in the hot-plate test, tail-pinch test, acetic acid-induced writhing test and in the early phase of the formalin test in rats. the activity as blocked by narcan.

yes, nigella sativa seed oil is REVERSIBLE BY NARCAN!!! very important.

the seed oil is cross tolerant with morphine, but apparently not the other way around.

the polyphenols have some analgesic activity, but it is still poorly understood. most likely the analgesia from the polyphenols is not from activity on the opioid receptor sites. the opioid activity comes from thymoquinone.

last night I took the seed oil for the first time. ingested a bit more than a tablespoon. about 30-45 min after eating the oil, my stomach was in very minor discomfort and I was experiencing opioid effects similar to kratom, but less complex. the addition of a tea made of three lanced and partly dried poppy pod was made. a tea of three unlanced pods from the plants I grew(remember alk content will vary in poppy pod) is usually a bit short of a full nod. with the seed oil, I used a much lower dose(taking into consideration the pods were lanced and much morphine was lost to collecting opium), and achieved a round trip ticket to nodland.

all in all, THIS STUFF IS GOOD! pretty easy to find, and works wonders as an opiate augmentation. I will give more reports of my use of the seed oil as an intoxicant on its own and as augmentation for oxycontin and kratom

commonly known as Black cumin it is said to greatly potentiate the effects of opioids,Does anybody know about this?Anybody tried this before?

[darkglobe]

Originally Posted by RoboCodeine7610

SWIM already posted this in another thread but thought this thread was more appropiate:


commonly known as Black cumin it is said to greatly potentiate the effects of opioids,Does anybody know about this?Anybody tried this before?

Where did you get that info? I'll have a look into it, but... well don't believe everything you read!

[fiveleggedrat]

To whoever asked, There was a discussion above regarding use of diphenhydramine as codeine potentiator, and there was mention the use of Diph in relation to overwhelming the codeine experience. Swim posted his off topic info in an effort to provide info that using it, even at reasonably low levels, is not always appropriate for everyone.


Too many people say the same things over and over, that are not true, especially regarding potentiators. Swim is tired of ignorance regarding opioid potentiators.

"Use item A at this dose, add item B at that dose..." Well, Swim followed instructions from here that reputable members presented, and Swim either 1) Ruined/Wasted a good dose or 2) Had a bad trip relating to bad ideas.

Drug use/medicine needs to be highly individualized.

Swim states all of the above with only the best intentions, not complaining. Swim does lots of experiments regarding opioid potentiation, especially for codeine and similar, and only wants the best info available.

If you want to know where Swim's research is, he's working on it. Swim is waiting to post until he has STRONGLY conclusive information that applies to more than just him.

[flipper70]

Thank you for that honest comment - it was swim who originally asked about the antihistamines - and Ive been advised in other threads to use it. swim would never take chances and from the info here would not follow up the idea. swim appreciates all swiy comments thanks.

[RoboCodeine7610]

Originally Posted by darkglobe

Where did you get that info? I'll have a look into it, but... well don't believe everything you read!

Well, Swim is not sure if he can give you the link to where he found it, since it's another forum, please tell swim if it's okay.
But swim did post a lot of links in this thread http://www.drugs-forum.com/forum/showthread.php?t=67051
Please, do have a look into it, swim would really appreciate your opinion.

[flipper70]

Thanks swiys for the response to the antihistamine thing -swim wont try cwe with those - will stick to c codamolxx

Reputation Comments on this post:

no problem :)

[fiveleggedrat]

Off topic, but noting here for reference that Swim has experienced psychoactive effects with Diph as low as 75mg.

Reputation Comments on this post:

Off topic so why post?

[Micklemouse]

Putting the first sentence into a search engine brings up the original post & several other references - this is often the case in these instances. Don't post links to other forums, but state that it was found on another forum when quoting.

[Micutzul]

Everything here from a Vampire's personal experience :
*in his CWE , he's always left with an amount of caffeine anywhere from 50% to 80% of the codeine dose he'd say *
So

Codeine + Caffeine +

1. Dxm , (up to 100 mg) Alcohol , a couple of beers , -beautiful experience
Does change the profile of the experience a bit , but it's still a codeine high

2. Alcohol , great experience , might get a little sedating but the vampire loves it either way and it's still a codeine high , depending on alcohol dose

3. Alprazolam (1 mg ) + Alcohol ( a little gin tonic ) - great experience , not sedating at all , once the Alprazolam was in . He actually felt like a 50/50 Codeine/Alprazolam high at times .



Now the vampire has mixed codeine with a lot of other stuff at high doses, but then again he's always mixing everything with everything and usually has tons of fun . Tried itw with tramadol , weed , high doses of dxm , high doses of alcohol , ( maybe even fenobarbital , he kind of doesn't remember ). Either way , for his personal use, he enjoys mixing codeine with almost anything , high doses , low doses of 2 or 3 or 4 drugs at the same time , pretty much whatever is available , but most people consider the vampire INSANE )


OFF TOPIC - If you ever get the idea of mixing like 400 mg of DXM with coffee , alcohol and 1500 mg Benzydamine , you might have a weird experience , kind of like feeling neither dissociated nor delirious , but feeling both at the same time , while feeling sober at times - kind of very very strange , at least that was the Vampire's experience .

Have fun people !

[Hover]

Originally Posted by Micutzul

Alprazolam (1 mg ) + Alcohol ( a little gin tonic ) - great experience , not sedating at all , once the Alprazolam was in . He actually felt like a 50/50 Codeine/Alprazolam high at times

Hi all, new member here

Swim's experience with this combination minus the alcohol is very similar especially when preceded about an hour prior with the juice of 4 freshly pressed large white grapefruits (not red), that yields about 20 ounces of juice.

Short-acting Alprazolam is one of the benzos less likely to induce sleep despite strong relaxing properties and providing a benzo buzz that's only second to clonazepam in this class of drugs, in Swim's opinion. But Clonazepam is long-acting and can easily lead to sleep when taken with a sedative opiate such as codeine. Also Alprazolam is the benzo most potentiated by grapefuit juice for some biochemical reason, it's an ideal companion drug to codeine for those who enjoy the combination. Swim is beginning to feel the effects as I type this, and signals he is about to retreat to The Goof Sanctuary

[darkglobe]

Thanks for the input SWIM would never recommend Nutmeg as a hallucinogenic in its own right or to potentiate any other drug.

[RoboCodeine7610]

What about the black cummin seeds?What do you guys think?

[davestate]

Originally Posted by RoboCodeine7610

What about the black cummin seeds?What do you guys think?

Originally Posted by darkglobe

Where did you get that info? I'll have a look into it, but... well don't believe everything you read!

http://eprints.hec.gov.pk/1813/1/1742.htm

Try that dark globe, quite detailed R.E. Nigella sativa

[darkglobe]

How do you people find such obscure documents... thank you davestate

[RoboCodeine7610]

How do you people find such obscure documents...

It's really easy:

http://justfuckinggoogleit.com

[RadioHead]

Originally Posted by RoboCodeine7610

It's really easy:

http://justfuckinggoogleit.com

Hah that made me laugh, SWIM found it quite mean though

[cbfull]

I tried taking 10 tagamets with the codeine because it will supposedly inhibit the enzyme that metabolizes morphine. I was STILL feeling buzzed the next day.

So, tagamet does nothing to help the codeine conversion, but it does let you hang on to the buzz for much much longer.

[cbfull]

I just realized an error I made in an earlier post. There does not seem to be a way to edit my own post to correct it.

So I will just say this. Taking cimetidine along with codeine seems to prolong the opiate effect. The amount of time it is prolonged appears to be proportional to the amount of cimetidine taken with the codeine. The theory here is, cimetidine apparently blocks the enzymatic destruction of any morphine formed from the original codeine, that is until the cimetidine itself is metabolized, excreted or whatever. I'm not certain at this point how many mgs the tablets I took were but I believe they were 200mg. I admit I took ten of them, which looking back on it seems a bit foolish given i had very few facts to support what I was doing.

I suppose this could be an interesting experiment for someone who might have straight morphine (sulfate seems to be the usual pharmacological salt). My understanding is that morphine is generally fast acting and short-lived. Eliminating the "short-lived" part seems quite desirable and advantageous.

[Hover]

Originally Posted by cbfull

I just realized an error I made in an earlier post. There does not seem to be a way to edit my own post to correct it.

Join the club, see the mega-mess of a post I made while attempting to fix a quote.