Yopo - Anadenanthera colubrina Basics

[GDxCAT]

if you go with ayahuasca i suggest you use mimosa hostilis or psychotria virdis.

I believe these 2 will give more of the effects you are looking for. (traditional DMT as opposed to 5meo and 5ho).

[Randombutterfly]

Anyone knows if Mimosa has any effects when taken by itself? A friend has some powder...

[wapcaplet]

I purchased some A. Columbrinaexactly one year ago, and they've sat in
a cool dark place since then. A week ago I began the Cebil (AKA Vilca)
making process. After much</span>
online research, I determined that the best way to make Cebil
(Technically, Yopo is made with Andathera Peregrina, which contains
less tryptamines than A. Columbrina) was to get some Lime Paste from a
Thai grocery store. It's tough to find, but when you do come across a
Thai Grocer, just look long and hard. They'll definitely have it, even
if they don't know what you're asking for. It comes in a small plastic
tin, and the paste inside is contained in a plastic bag. Very amaturish
looking stuff.



So, I toasted the seeds over an open flame on a spoon. I advise against
this because when they popped, they jumped out of the spoon and flew
across the room. You'll definitely want to cover them. This can all be
done without much attention. They don't really burn, and most seeds
will pop at around the same time. It took about 10 minutes over a
candle to do this. lus another 5 minute searching around my Den looking
for lost seeds that had tried to jump away.



The outer brown shell is then peeled away. This is not quite as easy as
most people make it sound. It's certainly not difficult, but it does
require a lot of manual dexterity, and a catcher below to capture any
lost nut pulp.



The nut pulp is bright brown, and flakey. It seems to be two-sided.
You'll understand when you see them. Crushing this into a powder is
also quite difficult. It took me over an hour to do this by hand, but I
had no mortar and no coffee grinder. I used a piece of paper, a spoon,
and a credit card, and this worked fairly well, though it was certainly
time consuming. The Lime Paste is slightly wet, so mixing it with the A
Columbrina is not easy. It clumps into little balls. I used about a 1/4
ratio of lime to seed, but in the end, it was porbably more like 1/3.



A report I found online stated that leaving this mixture out to sit for
a while reduced the pain associated with the lime. I feel this was
true. I left the powder out overnight and it turned from light brown to
black in the air. Likely this was oxidation.



The next day, I poured the snuff on a nother piece of paper and ground
it down heavily with the spoon. I cut out what I think was about 3
seeds worth of material. In all, I'd prepared 11 seeds with one lost
under the couch. It may not look like a lot, but really, or snorting,
11 is quite a bit.



So I hemmed and hawed a lot, preparing myself for this experience. My nose, thanks to horrible allergies and a live-in cat, is always</span>
clogged very badly, and this morning was no exception. It took me a
while to blow out enough mucous to make the passage clear. When it was
reasonably clear, I took a deep breath and snorted one of the lines.
After about two minutes I did the other.



Really, there was no pain at all. It didn't hurt much beyond the
feeling of having both nostrils filled with faintly repugnant smelling
powder.



I left this mixture in my nose for around 15 minutes, then expelled it into a tissue. It all came out easily, in one big clump.



I experienced absolutely nothing from this experiment. I feel I did
everything correctly. I will attempt again soon with a larger amount,
and a clearer nasal passage.



While this process was long and challenging, so far, I see no reason to
fear this compound. The pain can be avoided by letting the snuff sit
for a while, and the amount of DMT and 5MEO DMT in the seeds is
incredibly low.



I sincerely believe all effects are Bufo related, but I am not a good
person to make this claim. If yoru face turns purple, that's the Bufo.
Mine did not.

[RoboCop]

"I sincerely believe all effects are Bufo related, but I am not a good person to make this claim."

I have a very good book on yopo snuff its history chemical makeup etc. The DMT and 5-meo-dmt is not nearly as low as you think. Effects can be felt with a small amount of seeds. All my reading shows DMT to be the dominant chemical in the experience. I have no doubt of this being true.

[mouthwater]

I understand this is an old thread, and because it is stickied, I feel the following information is worth "bumping" for.

Originally Posted by RoboCop

"I sincerely believe all effects are Bufo related, but I am not a good person to make this claim."

I have a very good book on yopo snuff its history chemical makeup etc. The DMT and 5-meo-dmt is not nearly as low as you think. Effects can be felt with a small amount of seeds. All my reading shows DMT to be the dominant chemical in the experience. I have no doubt of this being true.

The following excerpt comes from Jonathan Ott's "Pharmanopo-Psychonautics: Human Intranasal, Sublingual, Intrarectal, Pulmonary and Oral Pharmacology of Bufotenine" which was published in The Journal of Psychoactive Drugs in September, 2001.

"Considerable chemical work on Anadenanthera shows conclusively and consistently that bufotenine is the only significant alkaloid in mature seeds of both species used for snuffs. [references available in article] Up to 7.4% bufotenine has been found in seeds of A. peregrina var. peregrina, only 0.04% 5-MeO-DMT and 0.16% DMT; 12.4% bufotenine in A. colubrina var. Cebil, with but 0.06% and traces of both tryptamines, respectively. Seven studies of 15 samples of Anadenanthera snuffs likewise showed bufotenine to be the only tryptamine present in significant amounts (up to 2.67%, with only traces of 5-MeO-DMT and DMT) [references available in article].

According to Ott's research, DMT is not the dominant chemical in the experience-- bufotenin(e) is. Anybody interested in Anadenanthera preparations should read the aforementioned paper.

[tip]

With the yopo swim said you gotta suck it up in to your nose as long and hard as you can in 60 seconds. Swim does this with 7 lines!! Some how it does not end up in swims throat. Swim also peeled the seeds and did not toast them. Then coffee ground then in a breville with baking soda so the snuff was a bit sticky, results were hyperspace.

You can get anesthetic "Lignocain" cream stick this up your nose and poke a dab of the shit on the roof of your mouth where your nasal cavity ends. Wait 2 seconds then your nostrils and back of your mouth go numb then SNORT.

[marleysherb]

SWIM still has his yopo seeds from the first encounter with them. In SWIM's experience, yopo is a complete waste of time and feels like HELL. The snuff tastes horrid, makes you nauceous, and gives you a head ache the next day. If I were a newbie, i would start with aya instead of yopo. I keep my yopo seeds only to remind me of how bad a drug can be.

[fatal]

From my research yopo seems to have a very different effect each time even on the same user. The same dose has produced in one individual a ++++ one time with complete loss of reality and a ++ with minor visuals and projectile vomitting another time. The second experience was not noted as markedly unpleasant just not necessarily good. Clearly some people also generally have a bad reaction every time they imbibe the snuff. Its most likely cause is certainly the fact that what we are considering here is a complex cocktail of psychedelic chemicals which shows great differentiation in the levels of alkaloids in different samples of materials and also in individual effects from one experience to another. It is likely that yopo will never be extremely popular as a drug because of its intensity, body load, and erratic dosage levels and effects. One for the connoisseur, surely. Well loved by those who appreciate it. It is an extremely spiritual experience from what I hear.

pz

[machine_elf]

Is bufotenine orally active in the absence of an MAOI? Does Bufotenine mix well with an MAOI?

[Nagognog2]

5-OH-n,n-DMT (bufotenine) is supposedly inactive orally. But Native folk have been ingesting Yopo via sinus and rectum for a long time. I've been fascinated by this molecule for many years, and the verifiable reports on 5-OH-DMT of and by itself remain scant. It would be nice if someone(s) sat down with some in the pure state and wrote up some good reports.

[Neosapien]

Originally Posted by Nagognog2

5-OH-n,n-DMT (bufotenine) is supposedly inactive orally. But Native folk have been ingesting Yopo via sinus and rectum for a long time. I've been fascinated by this molecule for many years, and the verifiable reports on 5-OH-DMT of and by itself remain scant. It would be nice if someone(s) sat down with some in the pure state and wrote up some good reports.

One has heard that this molecule could be converted to DMT through application of heat. Any ideas on what temp or a procedure?

SWIM has a good bit of cebil and yopo and plans on A/B extracting both roasted and unroasted seeds and comparing. Thoughts?

[TrippleBee]

I've noticed that this post hasn't been written in recently but I thought I'd share some thoughts on the YOPO snuff topic:

SWIM noticed alot of of people who've had no effects or only negative effects. The primary problem SWIM thinks with this YOPO snuffs is getting enough of this foul stuff up you nose. The problem is by doing lines the gag replex kicks in, or you just notice how horrible it is before you can done enough, which makes doing the rest VERY hard. SWIM met someone who said you need to do a 'shot' of it, normally done by someone blowing a large ammount up you nose, with a sort of tube. Any ideas on how people would do this by themselves would be greatly appreciated.

Secondly, the amount of lime to mix in, some people say 1 2 1 ratio, others 1:3 ratio, and others 1:10 ratio. SWIM heard that too much lime is NOT GOOD, the negative side effects such as nausea rise, and positive lessen. An ofcourse the burning sensation worsens. But not enough and nothing happens! So again more insight into this would be great.

[xctico]

has anyone has tried using afrin to numb the nostrils before inhaling yopo?

I found this article on the subject, it refers to the traditional preparation of Yopo.

RADITIONAL PREPARATION: It varies somewhat from tribe to tribe. The pods, which are borne profusely on the yopo tree, are flat and deeply constricted between each seed. Gray-black when ripe, the seed pods break open, exposing from three to about ten flat seeds, or beans. These are gathered during January and February, usually in large quantities and often ceremonially. They are first slightly moistened and rolled into a paste, which is then roasted gently over a slow fire until it is dried out and toasted. Sometimes the beans are allowed to ferment before being rolled into a paste. After the toasting, the hardened paste may be stored for later use. Some Indians toast the beans and crush them without molding them into a paste, grinding them usually on an ornate slab of hardwood made especially for the purpose.

Several early explorers described the process. In 1801 Alexander von Humboldt, the German naturalist and explorer, detailed the preparation of yopo by the Maipures of the Orinoco. In 1851, Richard Spruce, an English explorer, visited the Guahibos, another tribe of the Orinoco, and wrote: "...in preparing the snuff, the roasted seeds of niopo are placed in a shallow wooden platter that is held on the knee by means of a broad handle grasped firmly with the left hand; then crushed by a small pestle of the hard wood of pao d'arco...which is held between the fingers and thumb of the right hand."

The resulting grayish-green powder is almost always mixed with about equal amounts of some alkaline substance, which may be lime from snail shells or the ashes of plant material. Apparently, the ashes are made from a great variety of plant materials: the burned fruit of the monkey pot, the bark of many different vines and trees, and even the roots of sedges. The addition of the ashes probably serves a merely mechanical purpose: to keep the snuff from caking in the humid climate.

The addition of lime or ashes to entheogenic or stimulant preparations is a very widespread custom in both hemispheres. They are often added to betel chew, pituri, tobacco, epena snuff, coca, etc. In the case of yopo snuff, the alkaline admixture seems not to be essential. Some Indians, such as the Guahibos, may occasionally take the powder alone. The explorer Alexander von Humboldt, who encountered the use of yopo in the Orinoco 175 years ago, mistakenly stated that "...it is not to be believed that the niopo acacia pods are the chief cause of the stimulating effects of the snuff..." The effects are due to freshly confined lime.' in his time, of course, the presence of active tryptamines in the beans was unknown.

Yopo snuff is inhaled through hollow bird-bone or bamboo tubes. The effects begin almost immediately: a twitching of the muscles, slight convulsions, and lack of muscular coordination, followed by nausea, visual hallucinations, and disturbed sleep. An abnormal exaggeration of the size of objects (mocropsia) is common. In an early description, the Indians say that their houses seem to "be turned upside down and that men are walking on their feet in the air."




Also wanted to ask... does anyone have experience growing the tree? How long does it take for it to produce seeds given optimum weather..?

[Heyoka]

Nag, J. Ott also used pure bufotenine in his book and paper on these hallucinogenic snuffs.

Seeds that have sat around for months or years that were tested for alkaloids often contain only bufotenine. It seems to be the consensus amongst researchers that the effects are almost entirely due to bufotenine which can be in concentrations up to around 12%. The concentrations of dmt and 5-meo are too low for even threshold effects.

There seems to be quite a buzz on a number of boards concerning these seeds in the past few weeks with alot of positive things being said when the snuff is prepared properly.

[Heyoka]

Yeah, effects are bufo. I also tried making snuff with ground seeds water and lime and let it sit around for days. I tried about 800 mg with no effects. I'm not sure if it's crappy seeds or my prep tek. There was zero burn in the nose.

[sippy]

yes if you can make good extracts from cebil seeds((anadenanthera colubrina))
bufotenin is freely soluble in alcohol,,

calcium can react with the bufotonin to form a salt== is called calciumbufotenin
something like that,,

if that salt is not formed than you get nausea and vomiting,, certain if you swallow
the snuff from the seed,,, so it wil be wise t do,nt make a tea of the seeds

i think if you got a good bufotoninextract with the convertion into calciumbufotenin
than you can put it anywhere on your body where you skin is thin
with a good ectract you can get really far just like dmt but than diffrent

[Oppiut]

why do i not hear more about the calcium bufotine extraction from yopo seeds, and why is nobody mentioning the thread about this yopo extraction from awhile back? was it a fake extraction, has anybody tried it out and proven that it actually works besides the guy who wrote about it?

[Neosapien]

It works.
I posted it here:
http://www.drugs-forum.com/forum/showthread.php?t=38809

[Mescaloid]

SWIM've been reading on calcium bufotenate and found it very interesting. Seems active at 5mg (by vaporization) and lasts longer than vaporized dmt.

[Oppiut]

Re: Yopo - Anadenanthera colubrina Basics
SWIM've been reading on calcium bufotenate and found it very interesting. Seems active at 5mg (by vaporization) and lasts longer than vaporized dmt.

Is this from experience or from what SWIY has read, because SWIM tried that, and it never worked.

[Mescaloid]

From reading.

[Motumba]

Don't try to make Yopo-huasca, Bufotenine ingseted will make you feel aweful, heavy, with nausia also'

You can't wash the spice out of them with alcohol because of all the waxes'

You have to toast them and then powder extreemly finely the pulp of the seeds'

Then base extract with a solvent and clean the mole'
The problem is in the waxes the seeds have' takes a bit of work to get the bufo and the spice out'
10mg is a most awesome experience' the Bufo tightens your skin nicely before you roll out' hard hit' not for the faint hearted for sure'
Vilca seeds work well also, but it takes a lot of work'

Toad venom is a much cleaner experience'

Ez now'

Motumba'

[infekt]

Someone named Druiddream on another forum has another way of insufflating yopo: a nasal infusion....anyone try this before?


"If you were to do this one day, you could soak the snuff in an appropriate amount of acidified water, filter out the seed material, then basify it with calcium hydroxide until you get a fluffy precipitate at the bottom of your vessel. Then you can either pour this preparation (liquid + precipitate, but with no seed material in it) in a nasal sprayer after pouring out the saline solution that comes in it, or you can simply use a small 1/8tsp measuring spoon and insufflate the liquid, paying special attention to getting some of the fluffy precipitate in your spoon each time."

Seems like it would be a lot less painful than insufflating plant matter

[Motumba]

Hey all, swims'
Experiences and techs with Yopo and Vilca'


swim has been working on an extraction, but the waxes in the seeds is a complete pain in the ass, you shake this stuff a little bit you get emulsions'

In the snuff the Bufotenine is converted to Calcium Bufotenine, which is soluble in acetone''

Bufotenine is soluble in low ph water'

Roast the seeds until they split and deshell'
Try and roast the seeds as much as you can, so as the inner pulp is as dry as possible' (If you don't they clog the grinder')

Grind the seed pulp in coffee grinder'

Place the ground pulp in a pan and add clean water and acidify with hydrochloric acid to ph3'

Cook gently for 3 hours'

Strain off the water'

Place back to the heat and evaporate the water'

You will be left with brown slightly sticky resin'

Scrape up this resin and weight'

Weigh Calcium Hydroxide to match the weight of the resin'

Throw the resin in a glass jar and melt it with isopropyl alcohol, mixing into a thick syrupy liquid'

Add a little clean water mixing well and add the Calcium Hydroxide'

Mix all this up into a fine slurry paste'

Set aside to sit for at least 6 hours'

Place in a hot oven at 200-300F and bake until completely dry'

Let cool and add a generous amount of acetone'

Mix all of this really well'

The acetone won't dissolve the Calcium Hydroxide, but it does the Calcium Bufotenine'

Give the jar a gentle shake for 5 minutes and let stand to settle for 1 hour' (don't go mad, just gently slosh the solution around the jar)

Poor the acetone off filtering it through a coffee filter'

Add one gram of finely chopped parsley

Place the acetone over a very gentle heat and evaporate all of it'

The base salts left in the parsley are almost pure Calcium Bufotenine'

swom did a water extraction of the seed pulp and smoked it'
Hard body load, some visuals, lot of nausea'




Awesome journeys folks' he he he'

Calcium Bufotenine is freaking awesome stuff'


swom got back a little while ago, swim thought swim missed the hit and was going to try again'

1 min mark started sweating and feeling uncomfortable, guts started to churn, then things started to shimmer' some pain tingle in the back of head, slowly moving across head and over body' similiar to bufotenine acid salts, but they got a heavy body load that hurts your skin and muscles, this doesn't it just makes you tingle and go very numb' some nausia but it passes after the 3 min mark, now things are moving fast'
within 4-5 minutes everything folds'
baroque patterns moving very fast, everything covered in simbols, blues reds browns' body comletely numb'
Eyes closed is intence, out of body experience' incredible space of conciusness like being in a black sphere' geometric symbols massive swiling patterns everywhere, deep blues' golds greens reds, kind of foggy red mist to be looked through,, makes all your head and upper body tingle' no body load, just some nausia and sweating to start, this settles with 5 mins'
everything at the peak rushing very fast.
Full up and loaded at the ten minute mark then running for a full hour' swim's body comes back after 20 minutes, but it is incredibly hard to see eyes open, everything is twisting and vortexing all covered in mystical symbols that make swim's psychi crawal as swim tries to follow them'
Visions of desert and horses'
Awesome fuckin experience, comes on quite slow, compared to the smash you can get off spice, but the tiny piece swim done was deceptive' everything was colidoescoping by the 3-4 minute mark'

Intence experience'

swim didn't feel all lethargic and tired as swim have felt off of the acid salts'

Bit freaky at the top' swim still got the patterns everywhere an closed eyes is still very large and moving with subtle baroque lines and patterns, almost two hours!

fuck swim just looked 2 freakin hours, ha ha ha'


he he he going to eat now and then try this again'

awesome expperience' and an easy one to do' wooooooooooooooooooooosh' he he he'

swm looks at his skin and can still see the patterns' things swim focuses on still swirl in the centre'

Bliss'

Ok it is the acid salts that give the body load and nausia'

So if you get it off the snuff, it means that all the Bufotenine was not converted to Calcium Bufotenine'

If you swollow the snuff after snorting it the acids in your stomach convert it back to Bufotenine and you chuck up'

Don't swollow the snuff'

Let it do it's job then throw it out'

This is the most powerful, and swom not say this lightly, MOST POWERFUL' plant spirit swim has ever had the pleasure to experience'



At the 5 minute mark, swim was grabbed by an enormous whilwind vortes, eyes closed, eyes open swim almost lost veiw of everything'

A massive animals eyes peared at me through the veil, yellow brown and looking'

For some reason swim tryed to stand up out of the shock of it all and just colapsed into a twitching mass on the floor'

The experience was so powerful at one point swim believed swim fainted, something like a massive animal encroached swim and took swom's breath away'
Some heavy, almost panic at the peak'
Everything became so red and bright swim just tryed to turn away from it all'

swim voided his bowls completely and just lay there panting' in a pool of sweat'
All the muscles on swim's face began to writhe in a strange rythm, and swim's breath could be seen to shimmer in the air infront of him,
Strange noises emitted from deep within swim's body and throat'
swim's body just went off a done it's own thing, funky like stylee' all movements gurky and possesed'

The whole world turned into triangles pyramids and curves all vortexing extreemly fast, heavy blues, reds and golds'
Everything smokey and unclear to see but extreemly sharp' eyes open eyes closed

swim ain't got words'

swim barely got chance to see all the lovely baroque parterns before swim was transported extreemly fast completely across swim's known cosmos'
Like a tiny butterfly swim was battered and swished out and off, extreemly fast, no time for regret, swim didn't even realise swim had left swim's body'
swim came too on the floor'

swim sees a great red yellow desert, the winds whiping at the sands, tumble weeds spinning and bouncing, the sky red and thick with heavy purle clouds as if they had been made of, from the smoke of burning cities, there is great fire upon this land, everything is scorched and heaving with opressive heat'


fire in the sky'

red upon the land'

swim's mind now is sharper than a diamond cutter and my physical strenght is awesome'

Whipped swim's ass and the rode swim too death' and back again'
Heavy fuckin experience'

swim managed to get off the floor at the 50 minute mark and run a shower'

Thank fuckin God for a lovely hot shower folks whilst out on Yopo'
Extreemly excuisite, flowing light experience of which swim shall have to repeat more often'

As the water rolles over swim's head eyes closed swim sees a most wonder vision, as all the negatives slipped away with the water, everything turns blue silver iridecant diamonds, all dancing and twinkling behind swim's eyelids' flowing and dancing to the water cascading over swim'
An amazing experience to follow the water over your body and ancase you in the skin of a water snake writhing and twisting with it's own life'
swim's whole body became covered in these creatures'
swim watched in amazment as they spun and slitthered around swim's body
Some 90 min swim sat in the shower just sucking up the comfort of the water'
Didn't sleep until six this morning'

Wired now naturally and completely cleansed'

Perhaps the Jaguar sat on me' he he he' phew' ' . ' - - /,

Bliss'

MoTu'

Spun swim right around the world tree and back again'

Fuckin awesome and then some'

Cleansed'

A massive desert red and oppressive' and a huge black animal that suffercated swim' swim can still see the eyes' ~~~

[infekt]

what is a good OTC product once could use that contains Isopropyl Alcohol? (in USA)