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| (Meth) Amphetamine addiction Support for coping with Amphetamine addiction and Amphetamine addiction treatment. Amphetamines includes Meth & XTC. |
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#1
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Anxiety - methamphetamine withdrawal
SWIM feels like giving up on giving up. 3 days is all it has been, 3 days with no methamphetamine, the anxiety is all swim can feel, its not about craving anymore, its not about wanting to get high or even about wanting to feel happy, its about feeling comfortable in her own skin.
She should have planned this better. She should have prepared something to calm her down. All she has is her prescription Zopiclone, 15mg at night, but SWIM is taking at least 22.5mg at night and at least 7.5mg during the day, she thinks she should have got another script for Klonapin, but it took her a long time to come off the benzo, so she doesn't want to be repeating that cycle. And she has been drinking e2 for its miniscule dose of Taurine (213mg) which helps a bit SWIM thinks but can see why recommended dose is so much higher, and she is not too hot on the caffeine combo either, that cannot be helping. Should SWIM give up and try again when she is better prepared? If she keeps on keeping on or whatever the saying is, she is going to have some really nasty nights when her prescription runs out prematurely, cause right now thats about all shes got, and she is trying to be controlled, but all she is doing is staring at the clock and waiting for a time she thinks is ok to call bedtime so she can take 3 of the pills and sleep for a bit. |
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#2
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Re: Anxiety - methamphetamine withdrawal
SWIY has gone three whole days with no methamphetamine. For a substance one has been addicted to, thats quite an accomplishment. SWIM thinks SWIY should ride it out and finish the kick, since SWIY has already come this far. The anxiety should start to dissipate soon. Think about it this way: most drug withdrawals will produce effects opposite to those of the drug itself. If SWIY had been using meth at least partially to produce a sense of sociability, confidence, and disinhibition, its only natural that SWIY is going to experience some anxiety.
Perhaps doing this without Klonopin would be the best choice, albeit a difficult task, if SWIY had been using that alot in the past too. The caffeine and taurine may be something that is contributing to the anxiety, however, and SWIY may want to avoid use of that for a day and see if that helps. In SWIM's experience, even mild stimulants like caffeine can be very unpleasant when attempting to overcome an addiction. Perhaps cut back on the Zopiclone to a lower dose if SWIY is worried about running out, or go see SWIY's doctor and look into Zolpidem (Lunesta) which is just as efficacious if not more. Keep at it, this is not an easy thing to do, but SWIY can do it. The present might be very nerve-wracking and unpleasant, but remember that each passing second is one second closer to feeling better. Give it some time and think positively: SWIY is doing something very difficult, and something that the average person cannot even fathom, but she can accomplish this and be proud of herself. Hang in there, and perhaps look into some herbal supplements to help with feeling calmer and to aid with sleep. You can do it! |
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#3
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Re: Anxiety - methamphetamine withdrawal
i dont really know much about this drug, so i apologise for my ignorance. swim is also trying to come off drugs though, heroin. been on subutex for 2 years, and had last tablet sunday nite.
I just wana say that swim personally thinks that swiy shud ask bout increasing swiys doses? clearly its not enough to keep swiy on a level. as for feeling in ones own skin, i think that part just has to happen. swim has felt very alien at times, and as though nobody else around has a clue, and it is true. so i suppose the best thing to do is to be by urself for a while, and keep ur mind occupied by mayb watching films or wateva else swiy likes doing. i really hope it starts to get beta for you. |
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#4
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Re: Anxiety - methamphetamine withdrawal
Thanks for the replies. SWIM has been in bed for 3 days and hasn't had to deal with other people yet, dealing with herself is hard enough, she should have planned some supplements earlier, right now (this second anyway) every health shop is closed, though SWIM can hardly see herself managing to go out and buy anything now. But her last Z is starting to relieve some anxiety and she can probably take her night time dose soon.... it's 6pm and they take a few hours to kick in properly, but the last thing she should be doing is letting her life revolve around another drug......
There is no chance of getting this med increased, SWIM is lucky to get what she does. Lunesta isn't available here (but it is pretty much the same as zopiclone anyway). Very mixed emotions around the e2 drink, it seemed to be helping but SWIM is not sure. it's hard to keep busy with no energy, no motivation and anxiety screaming and kicking every inch of SWIM Last edited by ~lostgurl~; 16-02-2007 at 00:46. |
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#5
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Re: Anxiety - methamphetamine withdrawal
i know it must be hard for swiy, its 5 oclock in the morning here and swim has been up all night too. but it has been 3 days for swiy already, and if u gave up now, u would only have to do those same 3 days ova again at some point in the future anyway. think about it like that. swiy has already got 3 days out of the way, im sure there cant be much longer to go? u have gota stick it out, there would be no point in turning back now. has swiy got anybody close to them who knows wat they r goin through? cos i know it mite sound scary, but it mite help to ask them to come ova and c u, if only to acknowledge the fact that u r going through something as big as this, and just keep swiy company?
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#6
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Re: Anxiety - methamphetamine withdrawal
SWIM doesn't really feel like seeing anyone right now, the people she knows wouldnt really understand anyway. On the positive SWIM's 7.5mg dose of Z has kicked in, she doesn't feel any buzz or sleepiness. she does feel less anxious though, which is a relief, she feels almost normal, hopefully the effects dont fade off anytime soon.... but by then it should be sleep time anyway.
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#7
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Re: Anxiety - methamphetamine withdrawal
So SWIM used to be on a range of medications, including Effexor/Venlafaxine (SSNRI antidepressant) which she found significantly helped with meth cravings and anxiety coming off meth. Anyway, SWIM thought she may still have some of these pills leftover from a previous prescription so she went on a hunt for them. The reason SWIM had not looked for them previously was because she is unsure how long it will take for the desired effects, as antidepressants can take weeks to work.
Well take a look at what SWIM found all in one bottle: DSCF0167.JPG Yes Effexor & Lithium (which she doesn't think well help any right now) AND Klonapin!!! hopefully just enough to get her through the next few weeks without her using up all her Zopiclone by taking them during the day....... Yes SWIM has a very big smile on her face right now! God is looking down on lostgurl today and smiling that is for sure! Not sure how clear the pic is but she has 23 X 0.5mg Klonapin, 26 X 75mg Effexor and 36 X 250?mg Lithium plus 3 X unknown long white pills with nothing identifiable on them, she thinks they are lithium too. .....still smiling... yay |
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#8
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Re: Anxiety - methamphetamine withdrawal
Good to hear things worked out for SWIY... it always seems to happen with SWIM as well that little or nothing is available to help when he's kicking something (bad luck comes in batches, I guess) so that's really good news... best of luck with the kick.
P.S. careful with the Effexor, starting dose is 37.5mg I think. |
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#9
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Re: Anxiety - methamphetamine withdrawal
SWIM had a very bizarre night. When she found her bottle of pills last night (at about 10pm) she had already taken 3 Zopiclones so she decided not to have any klonapin, but took 1 X 75mg Effexor XR capsule. Up until a few months ago SWIM was taking 75-150mg Effexor per day for 18 months, and started on 75mg dose so she really didn't expect this to have much (or any) affect on her right away.
At 4am SWIM woke up and had the following conversation via IM with a friend: lostgurl: I just woke up and I feel like I’m pilling bro Friend: feel like you’re what? lostgurl: rolling Friend: lol...ok lostgurl: nah I feel fucked up, it’s freaking me out lostgurl: but I’m smiling, a weird fucked up smile that I can’t control Friend: you should enjoy it lostgurl: I feel real nauseas too lostgurl: shit almost got the weird e jaw thing wtf lostgurl: maybe the effexor wasn’t a great idea? Friend: or was it? lostgurl: no I feel like throwing up Friend: mmmm...yummy Friend: j/k lostgurl: definitely got the e teeth jaw thing happening wtf is going on! Friend: dunno Friend: take some e by chance? lostgurl: I guess that is possible, but can’t imagine how, no that’s not possible Friend: you still kickin'? lostgurl: was just sick lostgurl: I don’t feel right Friend: whats wrong lostgurl: dunno but it not right lostgurl: hot and cold, sick, smiling, head feels weird, body feels tingly Friend: withdraw symptoms? Friend: how long has it been btw? lostgurl: nope Friend: 3 days? lostgurl: 3 days lostgurl: I think its cause I took an antidepressant effexor last night lostgurl: but I took effexor for 18 months so this is weird Friend: I want those orange pills lostgurl: klonapin? Friend: yes lostgurl: I don’t think I took one of them yet lostgurl: why do you? Friend: I like my klonapin with methadone....by itself it really doesn't do much for me lostgurl: lol lostgurl: I'm smiling and I don’t know why Friend: well that’s cause you talking to a hotty Friend: a snobby one I hear too lostgurl: really, thanks for clarifying that, now why do I want to be sick though? Friend: that part I don’t know lostgurl: I can't think, gonna rest a bit SWIM is still feeling slightly hung over from this, her jaw and teeth feel weird and her head is still kinda fuzzy. It felt like she was on MDMA but without the euphoria. She took a Klonapin about an hour ago and seems to be coming right now. Very low levels of anxiety too so thats good! |
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#10
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Re: Anxiety - methamphetamine withdrawal
No surprise from here on the strength of effects with 75mg, a few months is plenty of time to lose all tolerance to an antidepressant.
SWIM started on 37.5mg/day of Effexor XR a few days ago... he's actually been feeling very wired/euphoric today on it, almost hypomanic. Not a bad serotonin-type buzz, except for the nausea & headaches... trouble is, using it normally as an antidepressant means feeling this way all the time, which is a considerably less pleasant prospect... ![]() Anyway, keep us updated on how things go for SWIY...
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#11
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Re: Anxiety - methamphetamine withdrawal
Interesting Nicaine, SWIM feels a bit hypomanic too actually...... hmmm. What else has SWIY been taking? vitamins/supplements/sleep aids? SWIM thinks maybe the e2's she has been drinking interacted with Effexor, because she started on the same dose and took it with and without meth for 18 months and never noticed anything even slightly like this. SWIMs jaw is still clenching, but she is feeling much better than she was yesterday evening, and better than the early hours of this morning that is for sure!
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#12
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Re: Anxiety - methamphetamine withdrawal
Quote:
Quote:
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#13
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Re: Anxiety - methamphetamine withdrawal
9 days free of meth and SWIM is feeling much better! Still a bit of anxiety, but minimal compared to the first 3 days, though SWIM is taking a few Clonazepams, as needed, but is not finding she needs them all that much..... though she wishes she had access to them during those first 3 days!
SWIM is starting to feel more energetic and more motivated, she spent the week sleeping and eating junk food but last night she did the weeks dishes that she couldn't be f**ked doing all week (big pile). SWIM is also feeling somewhat positive about life without meth, she's not convinced yet, but she has at times felt like life is actually better now........ she's hoping thoughts like this will frequent her conciousness more often. As for the Effexor "trip" SWIM still cannot figure it out, the slightly pleasant and also slightly unpleasant seratonin buzz SWIM felt took over 24 hours to leave, so SWIM has decided to leave the antidepressants alone for the time being. SWIM will hopefully be getting some Taurine, phenylalanine, Melatonin, Vitamin B-6 & Vitamin C later today and will report back with effects, as she is very keen to use natural supplements if they really work..... SWIM has doubts but she is hoping for the best. |
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#14
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Re: Anxiety - methamphetamine withdrawal
swim just joined thsi forum tonight, but has been without meth for almost 2 years, been on klonopin, busiprone, xanax & paxil for 2 yrs, urge is still there, but no bad withdrawl anymore past the first 60 days...still smoke great bud
stick with it, its better kniowing theres more of us |
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#15
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Re: Anxiety - methamphetamine withdrawal
Update: SWIM has 2 weeks clean of meth, and things are not as she expected….. Every time in the past that SWIM has tried to give up she has felt depressed, exhausted, no energy, constant cravings, no motivation, even after 2 months. But this time SWIM is manic. Crazy manic, unpredictable manic, and doing things she will probably regret somewhere down the track, but SWIM feels fucking fantastic, like she is high.
Most of the anxiety left after about 4 days and SWIM has not been sleeping much, maybe 5 hours a night induced with Zopiclone. The Clonazepams are almost gone, but SWIM hasn’t taken one in about 4 days. SWIM went to a naturapath on Thursday or Friday and got all the supplements below but so far she is unsure about what is doing what for her. Something in the mix is making her less manic in the mornings, which is a good thing but feels like a bad thing as SWIM is loving the manic, it feels better than any high she has ever had. Now SWIM has been trying to understand what is going on with her cause it just doesn’t seem right that she feels this good this soon. She’s putting a lot of it down to Bipolar, but there is also the independence and taking control back of her life, not relying on drugs to make her feel good. Then there are the supplements but SWIM was feeling like this before them, except for the Taurine which SWIM was taking through e2 energy drinks, So maybe this is all Taurine buzz? Or maybe it’s the sugar and the caffeine in the drinks? Most likely a combination of it all but SWIM has done this dance before and her whole world was the total opposite of what it is right now. A friend of SWIM’s dealer popped over last night just to say “HIGH” yeah right, he’s never been to SWIM's place before, anyway SWIM just told him “no thanks don’t need or want your shit and I’m busy so bugger off” Was not tempted in the least. That has never happened before. If it is under her nose she would never have dreamed she could say NO. SWIM has been wanting to post this for a few days now but most of the time she has been too manic to focus and put it all together. Anyway, below are the supplements, SWIM couldn’t get any melatonin as it is ‘prescription only’ here so she will talk to her Dr later this week about maybe adding this to her concoction. The below are what SWIM was told by the naturapath to take, and SWIM has bought all the supplements, she hasn’t had the protein shake powder yet and she only took the B&C Vitamin for the first time this morning cause she thought it was overkill, and SWIM did not feel that good after this mornings doses taking B&C complex plus Ultra C plus B6 is a bit too much of something (blurry eyes, head fog) so SWIM will need to play around with supplements a bit more to get it right, any advice out there on this? Extra B + C Take 1 pill 1 hour before breakfast A high potency balanced B-Complex with 500mg Non-Acid Vitamin C Contains: B1, B2, B3, B5, B6, B12 Calcium, Biotin, Choline Bitartrate, Folic acid, Inositol Vitamin C Ultra C 1000 Take 1 pill 1 hour before breakfast & 1 pill with dinner Advanced Poly-ascorate Vitamin C Complex with Bioflavonoids Contains: Vitamin C Calcium, Magnesium, Potassium Bioflavonoids, Rosehip, Zinc B6 Take 1 pill 1 hour before breakfast Contains: Pyridoxine Hydrochloride 240 mg DL-Phenylalanine 500mg Take 1 pill 1 hour before breakfast Contains: D-Phenylalanine 250mg L-Phenylalanine 250mg Women’s Multivitamin & Mineral Take 1 pill with lunch Multi Mineral Take 1 pill with dinner Taurine500mg Take 1 pill 1 hour after dinner or in the evening Cannabis Sativa 30c Take 2 tablets 15 mins apart up to 6 doses per day for cravings as req. HOMOEOPATHIC Protein Shake Powder Can substitute or be used in combination with breakfast or dinner Last edited by ~lostgurl~; 27-11-2006 at 05:47. |
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#16
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Re: Anxiety - methamphetamine withdrawal
I don't know anything about the benefits of taurine, but it sure seems like cutting out all that caffeine and sugar would be a good idea. Especially if the anxiety returns. Best of luck to SWIY.
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#17
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Re: Anxiety - methamphetamine withdrawal
Quote:
This notion of feeling better (which is more the memory of past cocaine kicks) has not gotten SWIM away from his own use of stimulants, but it has been pushing him closer every day... he's got a few more days of Ambien withdrawal + a delivery on the way, then he intends to weigh everything & make some serious choices. Even if it's just getting away for a few months or something. Can SWIM drop SWIY a few PM's if he decides to kick? Just for the contact with someone else doing it. Or if SWIY wants to drop him a PM with any tips or suggestions, he's open to it... he's been pretty disconnected from what the rest of the human race considers everyday/normal life. Last edited by Nicaine; 27-11-2006 at 07:27. |
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#18
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Re: Anxiety - methamphetamine withdrawal
SWIM has not felt manic in 3 days, she still feels happy, and quite positive about her decision to quit meth, no cravings still (thank God) but she is definitley missing the manic though she could see it was leading to trouble (not drug related trouble just trouble
) She had her first good night sleep last night - 7 hours and feels much more refreshed this morning than she has on previous mornings, especially the last couple which she woke up feeling very groggy. As far as the supplements go she has stopped the B&C complex, but is still taking the rest, she recommends taking no more than 750mg Taurine at night and not right before sleep. She tried her protein powder in a smoothie and it tasted pretty good so she palns to do this on a regular basis now. Off to the Dr today to talk about a substitute for her Zopiclone sleeping pill and after that the only thing she still needs to quit is cigarettes (maybe a new years resolution?) SWIM has not been very active, despite her increased energy, she thinks she is just being lazy though and plans to start getting out and about more (hmmm near future?) especially before she puts on too much weight - she has put on about 15 pounds in 2 weeks which doesn't seem too bad for the amount of food she has been eating and her inactivity. Her main issue at the moment is the lack of mania, which felt like a sober high to SWIM, and she is worried that without some sort of high she will find herself getting bored, this hasn't happened yet though.... Has anyone else felt manic after coming off meth? It seems that most people swing the other way with depression and tiredness, as SWIM usually has in the past, but would find it interesting to talk to anyone who has experienced anything similar to this, even if it was withdrawing from another drug. SWIM will keep updating as things change for her. Last edited by ~lostgurl~; 16-02-2007 at 00:57. |
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#19
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Re: Anxiety - methamphetamine withdrawal
Quote:
My congratulations go out to SWIY for keeping up the struggle against this demon. SWIY really seems to be doing quite well, and its not an easy habit to give up. I hope these posts can serve as an inspiration to others in the future. |
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#20
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Re: Anxiety - methamphetamine withdrawal
Thanks for the words of wisdom FTSL, you are right that SWIM should try some of these alternatives. They take a little more effort than just taking a pill as such, but would be worth it if it gives SWIM what she is looking for without the use of a substance.
SWIM went to Dr today, and her Dr thinks she should hold off quitting Zopiclone (her sleeping pills) and cigarettes for awhile and she should just concentrate her energy on giving up meth. She also upped SWIM’s dose of Zopiclone from 2 X 7.5mg to 2.5 X 7.5mg so that she can take half a pill during the day for anxiety if she feels like it. She said Zopiclone could easily work better than Clonazepam/Klonapin for SWIM’s anxiety as it is shorter acting, and it is not usually prescribed for this purpose as it would likely cause most people to fall asleep, but given that SWIM has a tolerance for Zopiclone it can actually work for this purpose. SWIM finds this very interesting as she doesn’t know anyone who is prescribed this pill for anxiety. SWIM’s Dr offered a prescription of Lorazepam as this is also short acting, but agreed with SWIM that it would be better for SWIM not to rekindle an addiction to Benzo’s. SWIM’s Dr also said that she has never actually prescribed Melatonin to anyone, and if SWIM is still interested in switching to this in a few months then she would refer SWIM to a psychiatrist for the prescription. Again SWIM found this quite strange as it seems to be sold at health shops in most countries. Another thing SWIMs Dr said is that she does not think it strange that SWIM has been manic for the past week or two, and she says many people actually go this way until their mind adjusts to the lack of desired substance, kind of a self protection mechanism, which was kind of comforting to know that she is not alone in this. She is also quite stoked that her mind still has such strong coping mechanisms after all she has put it through & all she has been through (Drug abuse & PTSD but to name 2) Below are some of the lyrics from the song “Breathing” by Lifehouse. SWIM is really digging this song at the moment, fits perfectly with the head space she is in. I'm finding my way back to sanity again Though I don't really know what I am gonna do when I get there Take a breath and hold on tight Spin around one more time And gracefully fall back in the arms of grace I am looking past the shadows of my mind into the truth And I'm trying to identify the voices in my head God, which one's you? Let me feel one more time what it feels like to feel love And break these calluses off of me one more time Last edited by ~lostgurl~; 11-12-2006 at 13:19. |
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#21
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Re: Anxiety - methamphetamine withdrawal
this swim has not had any meth for six months and swim still thinks about it most of the day, wants it most of the day and misses it most of the day. swim does not say this to disencourage any other swims, but swims recognizes what is said that if a drug is missing, an alternative substanence is used to cover. this swim tried booze, the crap amphetamines they have where she lives and now swim is on temazepam or oxazepam or xanax or some other pill she doesnt even know the exact name of. swim is supposed to start rehab on tuesday but swim does not want to go. because the only reason this swim is not using meth is because where swim lives there is no meth. and where swim lives they the drug councellors dont know it, so swim feels misunderstood as they keep thinking swim is or was addicted to ampetamines. and the doctor gives swim no pills to make her feel better as he feels she will get addicted to whatever he gives her.
but swim wants to tell other meth swimmers that she is amazed and so proud that they can quit. for this swim only quit as she moved to a place where there is no meth (yet...) it is taking swim a long time to put weight back on. she still looks a bit on the thin side. but swim eats well, exercises, listens to good music and found her self some hobbies.nobody knows what swim went thru, so swim cant talk to anyone. so swim is also very happy about this forum. |
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#22
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Re: Anxiety - methamphetamine withdrawal
Quote:
SWIM rarely seemed to be lucky enough to have both those factors going at once, altho he did finally quit somehow. He was depressed at the time, which actually seemed to help (like he knew he was gonna feel crappy with or without nicotine, so might as well not use it). Last edited by Nicaine; 03-12-2006 at 02:06. |
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#23
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Re: Anxiety - methamphetamine withdrawal
SWIM is almost convinced that Guarana is the key to her elevated moods. She took e2 energy drink out of her diet for 24 hours and she felt like crap. Not depressed but her head was really foggy, very tired and unmotivated... She kept taking Taurine and had caffeine and sugar from alternate sources but her energy levels were at zero and her mood was... meh... um not up or down. SWIM just restocked on e2 drinks and is now full of energy, happy, motivated, a touch manic....
Notes below mention that Guarana should not be mixed with ephedrine..... this could also explain why SWIM's first 3 days without methamphetamine were not so pleasurable (apart from the obvious) as it generally takes 3 days for methamphetamine to leave the system and she was drinking e2s during this time..... SWIM is very interested to hear anybody elses experiences with Guarana. Here's some info on Guarana from wikipedia: http://en.wikipedia.org/wiki/Guarana Guarana or Guaraná (IPA: [gu̯a.ra.'na], [gu̯a.ɾa.'na] or [gu̯a.ɹa.'na]), Paullinia cupana (syn. P. crysan, P. sorbilis), is a shrub or small tree in the Sapindaceae family, native to Venezuela and northern Brazil. The seed of the Guaraná fruit is a central nervous systemstimulant with thermogenic and diuretic properties. Guaraná plays an important role in Tupi and Guaraní Brazilian culture. The name 'guaraná' is derived from the Tupi-Guarani word wara'ná. These tribes believed it to be magical, a cure for bowel complaints and a way to regain strength. They also tell the myth of a 'Divine Child' that was killed by a serpent and whose eyes gave birth to this plant. In addition to other chemicals, the guaraná plant contains caffeine (sometimes called "guaranine"), theophylline, and theobromine. Water extracts of the guarana plant are central nervous systemstimulants due to the caffeine content. Energy drink manufacturers typically add synthetic caffeine or caffeine derived from coffee decaffeination. Energy drinks containing guaraná include Pepsi's Josta, Le-Natures Samurai Tea, PEP-G, Golly Guaraná, Socko, 180, Rockstar, AMP, V, SoBe Adrenaline Rush, No Fear, and Energy, Glaceau VitaminWater: Energy, Guaraná Power, Mountain Dew MDX, Monster, Crunk!!! Energy Drink, Sprite 3G, GURU 100% Natural Energy Drink, Von Dutch,Full Throttle and Pit Bull Energy Drink.Vores Øl and Molson Kick are beers containing guaraná. Whilst they are not beverages, other foods containing guaraná are Pit Bull Energy Bar,X-it mints and Jolt gum. Brazil produces several brands of soft drink from guaraná extract that contain no added caffeine. Each differs greatly in flavour; some with very little natural guarana fruit taste. In Brazil, sales of guarana drinks are second only to cola drinks. They are typically fizzy and sweet, with a very fruity aftertaste. Most guaraná drinks are produced in Brazil and consumed there or in nearby countries, such as Paraguay. Major brands include Guaraná Antarctica, Guaraná Schin from Schincariol and Guaraná Brahma from AmBev, Kuat, and Guaraná Jesus, a local Brazilian brand named for the druggist that formulated it.[1] Many local producers also create drinks not for export. Weight loss and health supplement Studies involving guaraná show benefits to cognitive function. [2] They have not been evaluated by the Food and Drug Administration (FDA) or similar government agencies. In the United States, guaraná holds a GRAS-status, i.e. generally regarded as safe and must be labeled as not intended to diagnose, treat, cure or prevent any disease. The Journal of Human Nutrition and Dietetics published a study in June2001 showing an average 11.2 pound weight loss in a group taking a mixture of yerba mate, guaraná and damiana, compared to an average 1 pound loss in a placebo group after 45 days.[3] A university study in Brazil of guaraná extract showed a platelet aggregation decrease of up to 37% of control values and a decrease of platelet thromboxane formation from arachidonic acid of up to 78% of control values. [4] This study may be significant to stroke and heart attack risk reduction because when excess thromboxane formation occurs, an arterial blood clot can develop, resulting in a heart attack or ischemic stroke.[5] A separate 1997 study of guaraná's effects on the physical activity of rats showed increased memory retention and physical endurance when compared with a placebo.[6] Other studies have shown antioxidant, antibacterial, and fat cell reduction (when combined with conjugated linoleic acid) properties in guaraná [7] Although side-effects of guaraná are rare, drugs.com recommends, "When considering the use of herbal supplements, consultation with a primary health care professional is advisable. Additionally, consultation with a practitioner trained in the uses of herbal/health supplements may be beneficial, and coordination of treatment among all health care providers involved may be advantageous". Drugs.com also advises not to mix guaraná with ephedrine.[8] Composition Guaraná seeds consist of mostly reddish vegetable fiber and resin with a small amount of oil and water. From Dr. Duke's Phytochemical and Ethnobotanical Databases [3]: Chemicals in: Paullinia cupana (alphabetical order, concentration given*) Adenine seed: Ash seed 14,200 ppm; Caffeine seed 25,000 - 76,000 ppm Catechutannic-acid seed: Choline seed: D-catechin seed: Fat seed 30,000 ppm; Guanine seed: Guaranine seed: Hypoxanthine seed: Mucilage seed: Protein seed 98,600 ppm; Resin seed 70,000 ppm; Saponin seed: Starch seed 50,000 - 60,000 ppm Tannin seed 85,000 - 120,000 ppm Theobromine seed 330 ppm; Theophylline seed 570 ppm; Timbonine seed: Xanthine seed: : Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press. (*) ppm = parts per million tr = trace Guarana contains different amounts, i.e., either less or more of the stimulants theobromine and theophylline and other alkaloids, than other caffeine sources. To compare values on this table with those of other plant sources search Dr. Duke's Phytochemical and Ethnobotanical Databases [4]. Last edited by ~lostgurl~; 07-12-2006 at 09:31. |
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#24
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Re: Anxiety - methamphetamine withdrawal
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Drugs of abuse such as heroin and cocaine (and possibly methamphetamine) sometimes create abnormal adrenal gland function which is masked during use by elevated levels of cortisol release at the same time. When the drug use is stopped, the altered glandular function may continue for a few days before becoming more normal. SWIM postulates that the altered function in this case would be an excess of hormones being released which trigger the production of epinephrine, which could lead to a manic state, or an edgy/anxious state as well. Guarana could certainly have interactions with the excess epinephrine in the body during these first few days of withdrawal that could lead to very unpleasant feelings like those that SWIY was experiencing. Interactions with residual methamphetamine in the system could be partially or totally the cause as well, SWIM is just giving an additional hypothesis to this interesting phenomena. SWIM takes it that SWIY is doing pretty well? SWIM's definitely glad that SWIY has lasted so long, its not an easy fight, but he has confidence that SWIY will prevail, and she certainly seems to be! |
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#25
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Re: Anxiety - methamphetamine withdrawal
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