Oral use - Sublingual Administration of Benzodiazepines

[RealGanjaMan]

Hi everyone,
I have a few Q's about Sublingual Administration, that I need answered before SWIM heads out tonight. SWIM has two 1mg lorazepam sublingual pills, and he wants to take them tonight. He has never used Sublingual Administration, and is not quite sure how to do it. He knows to put the pills under your tongue. He knows you let them dissolve. But do you have to let the dissolved powder/saliva absorb into your mouth before swallowing?

Also, does swallowing while the pills are dissolving cause any problems?


Thanks,
-RGM

[IHrtHalucingens]

Just pop em under your tongue, like you stated, wait for them to dissolve then swollow any extra saliva there may be. Itsa been SWIMs experience that benzos dissolve very quickly under the tongue and are absorbed almost intsantly. Just wait until its totally dissolved then swallow, it hits you hard and fast, pretty close to snorting (with water soluble substances).

Reputation Comments on this post:

Thanks for the info on Sublingual Administration

[RealGanjaMan]

Thanks, SWIM did just what you mentioned. It worked fine.

K+

-RGM

[csharpprogrammer]

I keep reading that the best route of administration for benzodiazepine pills is by holding it under your tounge. I am completely new to this route of administration. For example SWIM wants a little clonazepam buzz... does swim put one 0.5mg tablet under his tounge until it disolves completely then put another until he reaches his desired effects? How long until effects are noticed?

Also does the pill have to be designated for sublingual use, and what is the duration and power of the effects as opposed to oral administration? Thanks.

[Riconoen {UGC}]

swim always puts a kpin under his tongue, he feels a rush of benzo calmness almost instantly. it takes about 1.5 mills for swim to feel high and not just calm though.

[Nicaine]

Heh, SWIY should try using Ambien sublingually sometime. Separates the men from the Godzillas... Anyone who can do it without puking deserves respect. It does take effect faster, but that taste could keep someone awake for a week...

[csharpprogrammer]

For sublingual administration, all you do is let the pill disolve under your tounge?

[Nicaine]

Originally Posted by csharpprogrammer

For sublingual administration, all you do is let the pill disolve under your tounge?

Yes... it won't always lead to the drug taking effect faster though, but often it will (at least with initial effects; typically you won't get the full effect until digested, unless the pill is specifically designed for sublingual admin).

Also, the flavor/consistency of many tablets makes them bad choices for sublingual use, but most benzodiazepines taste mildly sweet/chalky.

[Jatelka]

From the rules:

• Use descriptive Topic Subject. This will help others find what they want to read. Topics with bad Topic subjects may be deleted! - there's nothing more annoying than looking at all those stupid "A stupid question" subject lines. I mean, I'm damn lazy, but how hard is it to type "A stupid question about (insert something here)"? As a rule of thumb, most thread titles should include the full name of the drug discussed.

A rule many tend to forget will cause a mass of warnings soon...

Thread title edited to include "Benzodiazepines"

[Psych0naut]

So SWIM is a gorrila then, Nicaine After a night on amphetamines, SWIM always takes some sleeping pills sublingually, which work great.
When SWIM takes 2 zolpidems sublingually, he's knocked out cold within 10 minutes, like he drank a whole bottle of whiskey.
SWIM always get's a good night sleep if he takes some zolpidems, it really makes a big difference the next morning, having had some sleep.
Though the metallic bitter taste of them is so awfull, SWIM found out last night that midazolam has the same nasty metallic taste as well, yuck!

[GForce]

Would this work well for Xanax?

[Jatelka]

Xanax is one of the quicker acting benzos anyway, but yes it would work (although possibly taste bad!)

[GForce]

Originally Posted by Jatelka

Xanax is one of the quicker acting benzos anyway, but yes it would work (although possibly taste bad!)

Yeah, SWIM was too impatient for a response so he tried it himself. It definitely worked but it was an awful taste. It took SWIM about 30 minutes to get the taste out of his mouth after using plenty of fluids and a cough drop.

[Riconoen {UGC}]

kpins dont taste like anything and hit you fast. choose kpin!

[Donmeka]

lol i swear ric is the walking klonopin. like the marlboro man but sexier

[radiometer]

One can purchase banana-flavored sublingual clonazepam. I can hardly imagine how disgusting it would be to take alprazolam sublingually.

[Psych0naut]

The binders in the pill probaply make a difference in taste as well. SWIM recently took a Roche 7.5mg midazolam sublingually, which tasted very discustingly bitter, like zolpidem and zopiclone.
When he took several 10mg oxazepams he didn't taste a thing, except for the same binders he tasted when he took melatonine sublingually.

[Donmeka]

Originally Posted by radiometer

One can purchase banana-flavored sublingual clonazepam. I can hardly imagine how disgusting it would be to take alprazolam sublingually.

having a presc to the 1mg alpazolam footballs i have to say it doesnt taste too bad or good. its salty and mildy sweet. banana flavored clonazepam sound just neat.

recently my alpazolam presc was changed to lorazepam 1mg and i tried that sublingually and it wasnt as bad tasting as alpazolam but the pills seemed more suited for sublingual use because when i pressed down on the pill it seemed to mold. so seems more soluable than alpazolam. and the taste was nowhere near as bad as alprazolam

[Riconoen {UGC}]

Originally Posted by Donmeka

lol i swear ric is the walking klonopin. like the marlboro man but sexier

hahaha that made my day.

[Donmeka]

SWIM got a hold of 2 10mg diazepams. SWIM will be taking 5mg sublingually with some MJ and 10mg when he gets home to sleep.

im glad to hear that ric haha

[radiometer]

Minor point: It seems to me that sublingual use of alprazolam is not very useful - when SWIM takes alprazolam orally, it takes less than 5 minutes for the effects to take hold.

[Donmeka]

thats true but it does hit you imo a minute or 2 i start feeling it. it could be just me but it takes much less than 5 min, a good dose would be whatever the SWIMs tolerance half the dose sublingually and half orally for an even nice effect.

[AchaeaPerson]

SWIA doesn't really get all the talk about bad taste with sublingual administration of pharms, he just puts the powder under his tongue, and if he doesn't move his tongue around much (keeping the powder UNDER his tongue) he doesn't taste it at all.

[csharpprogrammer]

SWIM notices that if he injests benzodiazepines too late at night, he will not get the desired effect. SWIM's theory is that his digestive system slows down late at night. SWIM would like to know if sublingual administration of benzodiazepines or other pharms would maybe be more efficiant for late night administrations. Could someone please explain the process of digestion and if a substance is completely absorbed in the mouth when taken sublingually?

[csharpprogrammer]

Originally Posted by Psych0naut

The binders in the pill probaply make a difference in taste as well. SWIM recently took a Roche 7.5mg midazolam sublingually, which tasted very discustingly bitter, like zolpidem and zopiclone.
When he took several 10mg oxazepams he didn't taste a thing, except for the same binders he tasted when he took melatonine sublingually.

How did SWIY feel with 7.5 mg sublingual? SWIM has 5mg in liquid form and wants to know what the effects would be.