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Tryptamines Tryptamines and indoles.

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  #1  
Old 04-06-2005, 14:10
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MET (freebase)

Tihkal says:
Lying midway between DMT and DIPT is the ethyl compound, N-ethyl-N-methyltryptamine, or MET. It can be made by adding ethyl acetate to a reaction mixture where the formamide of tryptamine (see under NMT) has been reduced to NMT but there is still a goodly excess of hydride still remaining. The free base, as an oil, shows oral activity in the eighty to one hundred milligram range, so going from a methyl to an ethyl does indeed protect the compound from total enzymatic annihilation when taken orally.


Now I got interested when someone mentioned MET in Drugnews section. Any trials of this in smoked freebase, if it is similar to DMT?

I just noticed that MIPT entry does not have any info on smoking either, I wonder if it works for MIPT..


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  #2  
Old 04-06-2005, 18:33
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Do you have a B.P. for this (boiling point)? This would say a lot about it's viability to be smoked. If it's low, like DMT or 5-Meo-DMT, then it should be possible to do an infusion into a plant material for trials. Should be interesting. Though that lop-sided ethyl might be either a problem, or a help! Get the rats! Oh George.......?
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Old 07-01-2006, 06:59
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Get the rats! Oh George.......?
What hapened to your monkey Bongo? Has he had enough of the experiments?
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  #4  
Old 06-01-2006, 21:28
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details...

Sounds interesting, any further syn details that we could look at?
Dosage?

Quote:
Originally Posted by anj0vis
Tihkal says:
Lying midway between DMT and DIPT is the ethyl compound, N-ethyl-N-methyltryptamine, or MET. It can be made by adding ethyl acetate to a reaction mixture where the formamide of tryptamine (see under NMT) has been reduced to NMT but there is still a goodly excess of hydride still remaining. The free base, as an oil, shows oral activity in the eighty to one hundred milligram range, so going from a methyl to an ethyl does indeed protect the compound from total enzymatic annihilation when taken orally.


Now I got interested when someone mentioned MET in Drugnews section. Any trials of this in smoked freebase, if it is similar to DMT?

I just noticed that MIPT entry does not have any info on smoking either, I wonder if it works for MIPT..
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  #5  
Old 07-01-2006, 00:26
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The entry for the 4-HO cousin in TiHKAL always sounded intriguing. Maybe it is just the less is more type of thing.

As for MET, one wonders if MAO plays some role in degradation similar to DPT, that is it partially metabolizes it but does not render it completely inactive orally, possibly rendering it much more active in the presence of a MAOI.

I B
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Old 07-01-2006, 00:33
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Quote:
Originally Posted by frankie
Sounds interesting, any further syn details that we could look at?
Dosage?
That is pretty much all there is under entry #47 in TiHKAL. There is some further discussion of MPT, but as far as MET goes that is pretty much it, unless there is discussion of it elsewhere in Shulgin’s writings that one is not immediately aware of.

I B
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  #7  
Old 07-01-2006, 09:15
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Bongo is fine, thanks. Regards amounts, this one would have to be worked up slowly ala Shulgin.
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  #8  
Old 17-10-2006, 17:47
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MET (freebase)

Lately swim has heard of some highly-exotic research materials...
2C-e,MDPK(MDPV)&MET(freebase)

There are reports written on experiences with 2C-e& MDPK but swim can't find anything on 3-[2-(ethylmethylamino)ethyl]-indole or MET swim tried yahoo'ing but came along DET the (diethyl)3-[2-(diethylamino)ethyl]indole based substance.

Swim wants to know if it is safe to assume that MET is almost an identical compound to DET...

Last edited by nanobrain; 18-10-2006 at 17:16.
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  #9  
Old 17-10-2006, 17:57
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Re: 3-[2-(ethylmethylamino)ethyl]-indole MET (freebase)

DET and MET are two very different compounds.
You can Find more info on it at another popular drug message board.

SWIG hasnt had a chance to tst the waters with this one yet but will be doing so within the next couple weeks.
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  #10  
Old 18-10-2006, 14:04
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Re: 3-[2-(ethylmethylamino)ethyl]-indole MET (freebase)

MET is structurally very similar to DMT and DET but you can really only use that as a guide as for what to expect.

I don't think it is "safe to assume" anything about an unresearched chemical especially one that you describe as "highly-exotic".

Take for instance AMT and AET. Very similar structurally but the dosage levels are very different and one is devoid of any visuals at all. The other point here is that AMT's mao inhibitor effects have been described as negligible but certaily not for AET.

Use much caution and do report back any of SWIM's experiences.
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  #11  
Old 18-10-2006, 17:04
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Re: 3-[2-(ethylmethylamino)ethyl]-indole MET (freebase)

i have read that AET is actually a weak competitive inhibitor similar to AMT.

dont know how true this is though.
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  #12  
Old 18-10-2006, 17:11
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Re: 3-[2-(ethylmethylamino)ethyl]-indole MET (freebase)

it is safe to assume nothing. alphabet soup it is not, even structurally related entities are molecular keys to very different doors - granted, there are many houses in thy fathers mansion.
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  #13  
Old 19-10-2006, 01:25
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Re: MET (freebase)

MET comes on much less aggressively than smoked DPT, and has a slower rise in effects than DMT, and is less powerful / mg. It seems to be really good a producing CEVs - sometimes when SWIM thinks there was not enough vaporized to acheive an effect, SWIM will close SWIMs eyes and will be having strong CEVs. SWIM has been a big fan of smoked DPT for a long time, and the big difference is that SWIM keeps expecting that strong electric body high which is just barely there with MET.
Overall MET has lots of potential, but it will need more work to unlock. It can probably reach stronger psychedelic effects without feeling like SWIM is about to have a heart attack from the overstimulation (ie - high dose DPT).

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  #14  
Old 19-10-2006, 21:18
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Re: MET

did i not read the rule about copy-pasting? harsh edit is served.

Last edited by nanobrain; 05-11-2006 at 18:00.
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  #15  
Old 21-02-2007, 06:38
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Re: MET (freebase)

*Bump*

Noone else has tested the waters with this substance lately?


Swim recently acquired an amount of met in what he expected to be a freebase.
It is a fine powder tho much like 5-meo-mipt. Can this substance be smoked via the method of placing on top of marijuana or would vaporizing it be the only efficient way? Also is this indeed a suitable form to recieve a product dubbed as freebase?
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  #16  
Old 21-02-2007, 07:20
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Re: MET (freebase)

Vaporize. Smoking on leaf burns some of the product and in inefficient. A crack pipe works best.
Freebases are not always oils. SWIM's product is a crystalline powder with occasional larger crystals mixed in. Same with the DPT freebase SWIM has seen, only it is even chunkier with big rocks interspersed in the powder. The freebases also tend to be a bit sticky since they have a lowish melting point and are hygroscopic. SWIY probably has the real deal.

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  #17  
Old 20-09-2007, 22:13
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Met

Does anyone have more information about this compound?
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Old 20-09-2007, 23:08
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Re: Met

do you know the IUPAC or any kind of abbreviated name? MET? N-ethyl-N-methyltryptamine?

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Old 20-09-2007, 23:26
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Re: Met

IUPAC: ethyl-(2-(1H-indol-3-yl)-ethyl)-methylamine

Tihkal has minimal information on it: "Lying midway between DMT and DIPT is the ethyl compound, N-ethyl-N-methyltryptamine, or MET. It can be made by adding ethyl acetate to a reaction mixture where the formamide of tryptamine (see under NMT) has been reduced to NMT but there is still a goodly excess of hydride still remaining. The free base, as an oil, shows oral activity in the eighty to one hundred milligram range, so going from a methyl to an ethyl does indeed protect the compound from total enzymatic annihilation when taken orally."

This thread has a few experience reports in it: http://www.drugs-forum.com/forum/showthread.php?t=24128
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Old 21-09-2007, 02:49
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Re: MET (freebase)

I have merged the threads.
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Old 22-09-2007, 21:10
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Re: MET (freebase)

there was a boy who was going to try it with a MAOI, but he can't get moclomebide(sp) easily so he will probably end up vaporizing it -

he's been told vaporizing it produces VERY harsh material which stings and then numbs one's throat (similar timeline to DPT vaporized)-

he's really wanting to try it with a MAOI, since it does not appear to be very active, orally-
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Old 04-10-2007, 22:36
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Re: MET (freebase)

SWIM also noted that vaporization leaves a carbonized residue, meaning some burns rather than vaporizes, unlike DPT and (clean) DMT.
Also, this product was never offered as a salt, in part SWIM suspects due to the same difficulties in making a DMT salt. Since SWIM finds that the drug still peaks about 15-20 minutes after vaporization, creating a salt would perhaps allow insufflation which could be an ideal route for this compound and not require a MAOI.
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Old 06-10-2007, 08:52
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Re: MET (freebase)

SWIM tried to make the hcl salt of MET, and ended up with black goo. MET does indeed taste horrible, and it also has a tendency to run like crazy in a pipe or on foil. These combine to make it difficult to smoke enough to break through as with DMT. A shame, because this is a truly remarkable chem, which in many ways compares favorably with DMT. A bold statement, I realize.
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Old 06-10-2007, 22:23
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Re: MET (freebase)

SWIM has found a freebase pipe to prevent the running. Does SWIY's MET also leaved a black charred residue ?
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Old 07-10-2007, 06:34
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Re: MET (freebase)

Quote:
Originally Posted by snapper View Post
SWIM has found a freebase pipe to prevent the running. Does SWIY's MET also leaved a black charred residue ?
Smoked fine, but SWIM wasn't willing to IM the goop, which was his original plan.
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