TEK - ancient coca preparations / extracts from the British pharmaceutical codex

[Benga]

Vinum Erythroxyli (N. F.)—Wine of Erythroxylon.

Related entry: Coca (U. S. P.)—Coca - Wines
Other tomes

SYNONYM: Wine of coca.

Preparation.—"Fluid extract of erythroxylon (U. S. P.), sixty-five cubic centimeters (65 Cc.) [2 fl, 95]; alcohol, sixty-five cubic centimeters (65 Cc.) [2 fl, 95]; sugar, sixty-five grammes (65 Gm.) [2 ozs. av., 128 grs.]; claret wine, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl, 391]. Dissolve the sugar in about six hundred cubic centimeters (600 Cc.) [20 fl, 138] of claret wine, add the alcohol and fluid extract, and enough claret wine to make one thousand cubic centimeters (1000 Cc.) [33 fl, 391]. Let the mixture stand a few days in a cold place, if convenient, then filter, and pass enough claret wine through the filter to restore the original volume. Each fluid ounce represents 30 grains of erythroxylon (coca). Note.—In place of claret wine, any other palatable wine may be used, according to the demand or preference of the prescriber or consumer"—(Nat. Form.).

Action, Medical Uses, and Dosage.—(See Coca.) Dose, 1 to 2 fluid drachms.

Related Preparation.—VINUM ERYTHROXYLI AROMATICUM (N. F.), Aromatic wine of erythroxylon, Aromatic wine of coca. "Fluid extract of erythroxylon (U.S. P.) sixty-five cubic centimeters (65 Cc.) [2 fl, 95]; compound elixir of taraxacum (F. 111), ten cubic centimeters (10 Cc.) [162]; syrup of coffee (F. 367) twenty-five cubic centimeters (25 Cc.) [406]; port wine, one hundred and sixty-five cubic centimeters (165 Cc.) [5 fl, 278]; aromatic elixir (U. S. P.), three hundred cubic centimeters (300 Cc.) [10 fl, 69]; sherry wine, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl, 391]. Mix the five first-named ingredients with four hundred cubic centimeters (400 Cc.) [13 fl, 252] of sherry wine. Let the mixture stand several days in a cold place, if convenient, then filter, and pass enough sherry wine through the filter to make the product measure one thousand cubic centimeters (1000 Cc.) [33 fl, 391]. Each fluid ounce represents 30 grains of erythroxylon (coca)"—(Nat. Form). Dose, 1 to 2 fluid drachms.



ELIXIR COCAE, B.P.C.
ELIXIR OF COCA.

Related entry: Coca - Elixirs
Other tomesMiscible Liquid Extract of Coca 16.50 | 3 fl.oz. 144 min.
Simple Elixir ... to 100.00 | to 20 fl. ounces


Mix.
Dose.—4 to 15 mils (1 to 4 fluid drachms).

EXTRACTUM COCAE, B.P.C.
EXTRACT OF COCA.

Related entries: Coca - Extracts
Other tomesLiquid Extract of Coca 100.00 | 20 ounces


Evaporate the liquid extract on a water-bath to the consistence of a firm extract.
Dose.—1 to 6 decigrams (2 to 10 grains).


EXTRACTUM COCAE LIQUIDUM MISCIBILE, B.P.C.
MISCIBLE LIQUID EXTRACT OF COCA.Liquid Extract of Coca 100.00 | 20 ounces
Alcohol (60 per cent.) ... to 100.00 | to 20 fl. ounces


Concentrate the liquid extract to 50 (10 fluid ounces) by evaporation, pour off as much clear liquid from the residue as possible, wash the residue with 10 (2 fluid ounces) of water, mix the washings with the clear liquid, and add sufficient of the alcohol to make up to the required volume.
Dose.—2 to 4 mils (1/2, to 1 fluid drachm).

Extractum Cocae Liquidum, B.P.—LIQUID EXTRACT OF COCA.
Coca leaves, in No. 20 powder, 100; alcohol (60 per cent.), sufficient to produce 100. Macerate the drug with 200 of alcohol for forty-eight hours, then transfer the mixture to a percolator, and percolate with sufficient alcohol to exhaust the drug. Reserve the first 75 of percolate; evaporate the remainder, at a temperature below 80°, to a soft extract, dissolve this in the reserved portion, and add sufficient alcohol to make up to the required volume. Liquid extract of coca is prescribed in mixture form or diluted with glycerin and syrup. It forms a turbid mixture with water, its waxy constituents being precipitated. Miscible liquid extract of coca is without this disadvantage. The content of total alkaloid in liquid extract of coca is very variable, ranging from 0.2 to 0.8 per cent., the average being about 0.38 per cent. This uncertainty in its composition causes the preparation to be little used. Dose.—2 to 4 mils (1/2 to 1 fluid drachm).

EXTRACTUM COCAE, B.P.C.
EXTRACT OF COCA.

Related entries: Coca - Extracts
Other tomesLiquid Extract of Coca 100.00 | 20 ounces


Evaporate the liquid extract on a water-bath to the consistence of a firm extract.
Dose.—1 to 6 decigrams (2 to 10 grains).


EXTRACTUM COCAE LIQUIDUM MISCIBILE, B.P.C.
MISCIBLE LIQUID EXTRACT OF COCA.Liquid Extract of Coca 100.00 | 20 ounces
Alcohol (60 per cent.) ... to 100.00 | to 20 fl. ounces


Concentrate the liquid extract to 50 (10 fluid ounces) by evaporation, pour off as much clear liquid from the residue as possible, wash the residue with 10 (2 fluid ounces) of water, mix the washings with the clear liquid, and add sufficient of the alcohol to make up to the required volume.
Dose.—2 to 4 mils (1/2, to 1 fluid drachm).

Extractum Cocae Fluidum (U. S. P.)—Fluid Extract of Coca.

Related entry: Coca (U. S. P.)—Coca - Extracts and Fluid Extracts
Other tomes

SYNONYMS: Extractum erythroxyli fluidum (U. S. P., 1880), Fluid extract of erythroxylon.

Preparation.—"Coca, in No. 40 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; diluted alcohol, a sufficient quantity, to make one thousand cubic centimeters (1000 Cc.) [33 fl, 391]. Moisten the powder with four hundred and fifty cubic centimeters (450 Cc.) [15 fl, 104] of diluted alcohol, and pack it firmly in a cylindrical percolator; then add enough diluted alcohol to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding diluted alcohol, until the coca is exhausted. Reserve the first eight hundred cubic centimeters (800 Cc.) [27 fl, 25] of the percolate, and evaporate the remainder to a soft extract; dissolve this in the reserved portion, and add enough diluted alcohol to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl, 391]"—(U. S. P.).

Description, Medical Uses, and Dosage.—(See Coca). Fluid extract of coca is of a deep greenish-brown or olive-brown color. It has the bitterness and astringency oft tie leaves, as well as the feebly aromatic, tea-like flavor. Its odor is slight. Dose, 10 to 60 minims.

Tinctura Cocae, B.P.C.—TINCTURE OF COCA. 1 in 5.
Used as a cerebral stimulant and gastric sedative. Dose.—2 to 4 mils (1/2 to 1 fluid drachm).
Vinum Cocae, B.P.C.—COCA WINE. 1 (elixir) in 8.
This is a strongly medicated wine. In order that it may be included in the class of medicated wines for sale without a wine licence, it must contain not less than half a grain of alkaloid per fluid ounce. Acts mainly in virtue of its cocaine. Coca wine differs from tea, in that the former beverage acts mainly on the motor areas and the latter on the psychical, Dose.—8 to 15 mils (2 to 4 fluid drachms) with water.


Vinum Cocae et Quininae Phosphatis, B.P.C.—COCA AND QUININE PHOSPHATE WINE.
Each fluid ounce contains 1 grain of quinine sulphate, 30 minims of liquid extract of coca, 4 minims of diluted phosphoric acid, with alcohol, detannated sherry and distilled water. Dose.—15 to 60 mils (1/2 to 2 fluid ounces)

OCULENTUM ATROPINAE CUM COCAINA, B.P.C.
ATROPINE EYE OINTMENT WITH COCAINE.

Related entry: Coca
Other tomesAtropine, in fine powder 1.00 | 5 grains
Cocaine, in fine powder 2.00 | 10 grains
Soft Paraffin, white 97.00 | 485 grains


Dissolve.

BUGINARIA COCAINAE, B.P.C.
COCAINE NASAL BOUGIES.

Related entry: Coca. In 1 Bougie
Cocaine Hydrochloride 0.011 gramme | 1/6 grain


Gelatin Basis, sufficient to fill a 1-gramme (15-grain) mould.

GUTTAE COCAINAE, B.P.C.
COCAINE EYE DROPS.

Related entry: Coca - Eye drops
Other tomesCocaine Hydrochloride 2.00 | 35 grains
Sterilised Water ... to 100.00 | to 4 fl. ounces


Dissolve the cocaine hydrochloride in the sterilised water.


GUTTAE ZINCI CHLORIDI ET COCAINAE, B.P.C.
ZINC CHLORIDE AND COCAINE EYE DROPS.Zinc Chloride 0.50 | 2 grains
Cocaine Hydrochloride 0.25 | 1 grain
Sterilised Water to 100.00 | to 440 minims


Dissolve the salts in the sterilised water. Zinc chloride does not make a perfectly clear solution with water, but the filmy deposit is not of importance, and no attempt should be made to dissolve it by the addition of acid.

Reputation Comments on this post:

	Good find
	very informative, thanks