Apomorphine for sexual enhancement

[Smarthead]

When Uprima (apomorphine by generic name) was launched in Europe as the first medical treatment for sexual dysfunction after Viagra, it was suspected that it could repeat the success of Viagra. It did not. Which doesn't mean that it would be a useless drug.

Apomorphine is a dopaminergic drug. It stimulates dopamine receptors. And dopaminergics are a blessing. If you know how to take them, and what to suspect. And if you can purchase dopaminergics at a lower price than the 10 dollars per milligram charged by official Uprima selling sites, or at US pharmacies for other dopaminergics such as Dostinex.

Unlike sildenafil (Viagra), apomorphine and other dopaminergics exert their pro-sexual effect not upon the erectile organ but upon the brain. Apomorphine provokes erections not by interfering with the plumbing of male sexual function (speak: blood supply to the penis), but the wiring necessary for arousal.

That Viagra only effects the plumbing, puts clear limits to its potential as a lifestyle drug. Viagra will do little for men whose plumbing doesn't leak. On the other hand, a good shot of additional desire can be a welcome life enhancement for many people with whom there is nothing wrong physically but who just feel bored with their everyday life. For them, apomorphine can be a real enrichment, and even a medication that saves their marriages.

Provided, they can afford it.

I meanwhile have substantial experience with apomorphine. I need about 6 mg to have a clear pro-libido effect. Buying official Uprima would cost me 60 US dollars a go. Well, I'm not rich enough to have 60-dollar habits. For this reason, I have long searched for an alternative supply of apomorphine.

Already a few years back, I had found a supplier of bulk apomorphine. I ordered a quantity of several gram, and did experiment with it. It was OK, but I'm not a chemist or pharmacist, and the raw apomorphine is difficult to store (it is suggested to store it under argon), and I'm not equipped to measure dosages of 6 mg of any substance. So I gave up on bulk apomorphine. Nevertheless, the source from where I bought the bulk apomorphine is still listed in the member section of the sexual enhancement package.

While apomorphine clearly is a pleasure drug (if taken at dosages below the nausea level), this is about all it has in common with its more famous colleague in name, morphine. Sure, apomorphine can be produced from morphine. But its pharmacological effects are completely different. Morphine is a sedative agent, while apomorphine is a stimulant.

Apomorphine primarily works as a dopamine agonist. Like most dopamine agonists, apomorphine is useful in the management of Parkinson's Disease (PD), a condition characterized by the loss of dopamine-producing neurons, or a decreased function of such neurons. Either way, a dopamine deficiency is the result, leading to severe motor function disturbance.

Apomorphine is a D1 receptor-specific dopamine agonist that makes it different from mostly ergot-derived dopamine agonists, which usually target D2 dopamine receptors, e.g. pergolide and bromocriptine. D3 and D4 dopamine receptors are less often targeted in the management of Parkinson's Disease.

It has long been documented that Parkinson's Disease medications have sexuality-enhancing side effects. It has to be noted that the sexuality-enhancing side effects hold true for many but not all dopamine-enhancing Parkinson's medications. Whether or not a dopamine agonist enhances sexual functions seems to depend primarily on the dopamine receptor sites it targets.

Reputation Comments on this post:

very informative

[WrtngCocaineTutorial]

Interesting text Smarthead.
SWIM is thinking about trying bromocriptine. Has SWIY any experience with any of these dopamine agonists?

[acolon_5]

A question about apomorphine. Is it addictive as morphine is? Is it concidered a narcotic? Can it be used to reduce or cancel out morphine w/d?

The topic of it being used as a sexual aid is quite interesting, and SWIM would like to learn more about it. The only concern is that SWIM being a recovering H addict, he worries that it may trigger his addiction.

[Benga]

this is a very informative post. I had no idea apomorphine actually stimulated libido that way. Unfortunately loss of desire is often something that is hard to deal with, especially if you're in a couple, sure you can try to "spice things up" but if your sexlife has already been pretty spicy and you just feel an overall lowering of your sex drive rather than just partner related boredom ( ie you don't feel desire for other partners or new things, just less sexual desire) , this doesn't really help. It's not a question of getting it up but just a question of actually feeling excited. And somehow many substances, when used regularly, seem to lower one's drive, even if some are initially quite arousing ( thinking of stimulants here). That and a busy lifestyle, lack of sunlight in winter etc...
A reccurant theme in Japanese media, many young Japanese couples are official sexless couples, especially after the first child is born. Does this really mean the husband pops in to suck-clubs after work and the ideal housewife has long onanistic activities and / or affairs, or is there something else.
Increasing physical exercise and getting up early somehow helps, but that's not all there is to it.
will be reading up on the subject.

b

[allyourbase]

I know nothing about apomorphine or is it apomorphone? anyway swim has often used morphine for sexual enhancement, one has to time it correctly though, before one runs out of endorphins and dopamine, but it really is the best sex one can have. even better than dressing up like batman and vaulting onto your partner from a the bedstand to the theme music from bonanza.....

[Benga]

Originally Posted by allyourbase

I know nothing about apomorphine or is it apomorphone? anyway swim has often used morphine for sexual enhancement, one has to time it correctly though, before one runs out of endorphins and dopamine, but it really is the best sex one can have. even better than dressing up like batman and vaulting onto your partner from a the bedstand to the theme music from bonanza.....

it is apomorphine. SWIM tried it two days straight and found it had no influence on his sex drive ( having no physical issues but interested in pleasure enhancement). to be noted that erections were "au naturel" as opposed to metal rod human dildo like quality of small amounts of sildenafil citrate (viagra), which can be fun as well...
again, getting up early / white light luminotherapy and exercise boost libido more for swim, or even chewing coca dopamine induced horny flashes ( more of a solitary pleasure as it is far from convenient or sexy).
quite a let down, as swim was expecting more from the mechanism described, a sort of mentally active / biochemical aphrodisiac, but this one seems to really deal with plumbing as well.
b

Reputation Comments on this post:

very interesting experience you have! SWIM was about to buy it

[WrtngCocaineTutorial]

Please tell. at what dose did SWIBenga have non existent effects?

[Benga]

Originally Posted by WrtngCocaineTutorial

Please tell. at what dose did SWIBenga have non existent effects?

two times 3mg.
having no physical problems down there when not drunk or under stimulants he didn't feel that much of a difference in erections, but this was not the motivation.
two 3mg doses in 24 hours didn't make swim more excited mentally ( sildenafil for instance, taken in 25mg doses tends to make swim physically sensitive ie prone to inopinate spontaneous erections for over 24hours).
swim was wondering if apomorphine would make him shall we say more horny ?
b