Cannabinoids and Cancer

[enquirewithin]

This is fairly hard for me to understand, but this Italian research suggests that certain cannabinoids inhibit the growth of cancer.

Abstract
Δ9-tetrahydrocannabinol (THC) exhibits anti-tumor effects on various cancer cell types, but its use in chemotherapy is limited by its psychotropic activity. We investigated the anti-tumor activities of other plant cannabinoids, i.e. cannabidiol, cannabigerol, cannabichromene, cannabidiol-acid and THC-acid, and assessed whether there is any advantage in using Cannabis extracts (enriched in either cannabidiol or THC) over pure cannabinoids. Results obtained in a panel of tumor cell lines clearly indicate that, of the five natural compounds tested, cannabidiol is the most potent inhibitor of cancer cell growth (IC50 between 6.0 and 10.6 μM), with significantly lower potency in noncancer cells. The cannabidiol-rich extract was equipotent to cannabidiol, whereas cannabigerol and cannabichromene followed in the rank of potency. Both cannabidiol and the cannabidiol-rich extract inhibited the growth of xenograft tumors obtained by subcutaneous injection into athymic mice of human MDA-MB-231 breast carcinoma or rat v-K-ras-transformed thyroid epithelial cells, and reduced lung metastases deriving from intra-paw injection of MDA-MB-231 cells. Judging from several experiments on its possible cellular and molecular mechanisms of action, we propose that cannabidiol lacks a unique mode of action in the cell lines investigated. At least for MDA-MB-231 cells, however, our experiments indicate that cannabidiol effect is due to its capability of inducing apoptosis via: 1) direct or indirect activation of cannabinoid CB2 and vanilloid TRPV1 receptors; and 2) cannabinoid/vanilloid receptor-independent elevation of intracellular Ca2+ and reactive oxygen species. Our data support the further testing of cannabidiol and cannabidiol-rich extracts for the potential treatment of cancer.

http://jpet.aspetjournals.org/cgi/re...t.106.105247v1

[Solidly-here]

Why take a chance?

Truly, Doctors don't know about these things. Just because 10,000 people who have their Cancer go away smoked Pot, this is NOT actual proof. Each of those 10,000 could ALSO have done something else (which actually inhibited the Cancer).

So, if you have Cancer, smoke your lungs out. Either, it will help your Cancer, OR you will spend less time thinking about your Cancer.

Just do whatever you think will help. If nothing else, believing in a cure helps many people cure themselves (the so-called placebo effect).

[Bajeda]

People also have been injecting massive amounts of Vitimin C (I think its that one, the one in oranges?) to fight cancer. There isn't much scientific data to support it, and it is quite controversial, but then again on the other hand people have been living years with malignant cancer that should have killed them a long time ago.

You just have to go with what works and you think is right. Neither scientific or anecdotal data is always right one part of the time, especially when much isn't known about something. You just have to use your judgement to choose what works best for you. So if cannabis helps people with their cancer they should keep using it, but they should also be on the look out for other things to help them.

[Solidly-here]

Vitamin C

This stuff is needed in our body. Most animals make their OWN Vitamin C, but people do NOT make any. This means that we must get all of it by foods we eat (yeah, Fat Chance), or by supplements.

Linus Pauling was a great believer in the power of taking much more than the minimum (the RDA, Recommended Daily Allowance). As Bajeda said, Vitamin C has (seemingly) helped many 1000s of Cancer victims . . . and they still live today.

At different times, I have taken 2,000 MG a day of it. I feel better. That's enough reason to take some.

If I ever get Cancer, I will be taking 5,000 MG, like Linus suggests (and hoping for a remission).
Until that time, I will take 500 MG most days. I mean: What have I got to lose?

[snapper]

The problem with antioxidants (ie vit c, E, etc) and cancer is that cancer cells can benefit from antioxidants as well to grow faster and live longer. They can certainly also be detrimental, esp. if there are a lot of extra ones to be had by a growing tumor.
As far as pot curing cancer, don't count on it..

[Akewstick]

Truly, Doctors don't know about these things. Just because 10,000 people who have their Cancer go away smoked Pot, this is NOT actual proof. Each of those 10,000 could ALSO have done something else (which actually inhibited the Cancer).

yeah like crunchy nut cornflakes, seriously, it must be them cruchny-nut-motherfuckign-cornflakes, i swear they healed me, i used to be a fucking cunt, and now i'm awesome, and all becuase of crunchy... nut.... fuckin.... cornflakes

[yj965]

I have a strong belief that if one with cancer or almost anything wrong with ones body can fight it with there mind. If its true we only use 10% of our mind then theres no tellin what our potential is. Im not saying that it works for everyone. Then again swim is not a doctor, swim has not been around a lot of people with cancer. But from swims experinces and things that swim finds acceptable, in theroy, mind over matter. If you have the will power to do this. I think this goes along with anything. Things with ones body and mind. All and all I wanted the thoughts on the idea of mind over matter from the outstanding persons on this wonderful site.
Sorry if I dont make any sence..... I am about three sheets to the wind.....
Let me know if I should or if it would have been better to start this in a new thread. I thank yall beyond words! All of you are wonderful!

[stoneinfocus]

I´m soooo wonderful, really, at least the 89,99765% of me which I´m not husing .. tell you what .. I cured my accident-injurys with hypnosis and laying on hands .. no need for shitty analgesia, somatropine, anabolics, ..., the completely cut off tibia would have grown together just by will power )

And next time I´ll ban the anaesthetic fom surgery, ´cause I have elarne dto use my will power so muchm I could control the pain, without the elcectric nerve-signals damaging my brain or daying of stress.

Or is will power engineering and developing agents like somatropine that will make sure, my cut off tibia will grow
and is the 90% deserted mind the agents not yet developed or used adequately?

[fatmanstan]

Originally Posted by co-incidence

And next time I´ll ban the anaesthetic fom surgery, ´cause I have elarne dto use my will power so muchm I could control the pain, without the elcectric nerve-signals damaging my brain or daying of stress.

Or is will power engineering and developing agents like somatropine that will make sure, my cut off tibia will grow
and is the 90% deserted mind the agents not yet developed or used adequately?

th

Look into surgeries performed under hypnosis, it was suprisingly effective, although those who practiced it were laughed at and made to look like "Faith Healers" or such.

I was going to find some links for you, but doing a simple search of surgeries under hypnosis revealed many valid links. Our minds are vastly undeveloped. I think, at least in part, this is a big reason why some of us are here on this board and others like it. Psychedelics provide a window into seeing how the mind works, and what could be possible. Look at studies done using LSD as a pain reliever in end-stage terminal patients. Patients claimed to understand that they should be in pain, and the pain was there, however it wasn't important anymore and didn't bother them.

Strange things happen all the time with sickness and disease. Miracles, if you want to call them that. Mind over matter is definitely valid, to a point. This isn't to say that if someone can't "will" themselves better, that they must be of a weak mind. Shit happens. And the world keeps spinning. Hopefully, we can all just find our place in all of it.

[stoneinfocus]

Must be some evidence if inhibited cell growth even in xenobiomaterial is inhibited by cannabidiol, maybe those examinations and investigations were conducted -as so often, by the suspicion of soem medics or scientists, or by some evidence that occurded during experianting, empirical data or abnormalities in cancer patients, peer groups, etc. ...

[stoneinfocus]

I´ve never "seen" despite on TV whre you can trick everyone with anything, that let me to belive, that there is the slightest evidence that these things work.

LSD is a very strong analgetic mean, stronger than morphine and very much longer lasting.
When I was on mescalin I went outside the disco stayed for 45min in freezing winter´s snow and didnt´n realize -no, not didn´t realize, Ididn´t feel it that it was cold I just saw it, I didn´t realize/feel the smoke in my lungs of a bong as hard as I pulled, nothing, ab-so-lutely nothing , you could have cut off my arm or a leg inch by inch and it wouldn´t have bothered me.

Show me a real live hypnotic who can do this, befor my eyes -not this indian needles-through-the-skin-bullshit and hang me up on them, which is as painful as a prick test for allergies, not to say that they´re on some kind of dope, also.

I agree that there´re some aspects in our minds, that are underestimated and not fully developed, but that´s imho definately not those kind of things, which are born out of wishful thinking and satsifying the pulic addressed curiousity and in turn making money out of it or going to the big public.

these hypnotic things are some "bring through the boring summer-news articles", ever returning TV-vamps.

that´s circus, other things are meditation to free ones mind of everything cause even then there´s all, and craftmanship, talent and hard dedicated work, you see, not the kind of things that one would be intrested in watching at or doing it oneself.

I dont0 think, if there are/were "supernatural" talents, that they could be controlled or trained, or used in any kind of way that´d be practical in any way in modern life, you see, even then who would believe it when they even don´t believe real life sport events because they might be on dope or not.
I mean, come on, is it happening, documented by an 1/1000 of a second, or not?

[stoneinfocus]

Idon´t believe in 40-60% of medically conducted studies either .. been there I know the humans, I read them and I see how, when and where they were faked and by whom and for what reason.And how much it did cost them.