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Old 03-09-2006, 04:50
BANGINCOLOR BANGINCOLOR is offline
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How to get better oral absorption of oxycontin

I've read tons of guides on how to properly inject pills....not my thing but after reading about the procedures, I wondered if some of that might enhance taking oxycontin orally.

Crushing up an 80 oxycontin, dissolving it in warm water, maybe put a small flame to it to get the fillers to seperate more and just eat it.

I read an insert from purdu-pharma that said oxycontin taken after a high fat meal increased blood plasma levels of oxycodone by 35%.

I thought of a major crush up session then putting the crumbs in a tablespoon of peanutbutter which of course is super high in fat.

What do you guys think about this?
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Old 03-09-2006, 13:35
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Im glad that SWIY decided not to inject pills, it's one of the most dangerous things one can do to ones body when concerning drugs. SWIF doesnt know that much about potentiating oxycontin orally but if SWIY is looking to use less oxycontin and recieve a higher effect one could also plug the crushed up pill. Rectal administration has a much higher availablity than oral therefore giving a much stronger experience. The onset will also be significantly more rapid giving a rushing sensation (although not as intense compared to Injection). Some dont agree with Rectal administration due to social barriers however it is commonly used in the medical profession for rapid administration of drugs when injecting isnt an option. An example would be an epileptic carrying rectal diazepam.
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Old 03-09-2006, 18:39
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I got no problem with putting it up there. I've read some people's post that say only certain drugs will work up there that, a drug has to be made for rectal administration.

Like suboxone is MADE to be placed under the tongue and absorbed/dissolved. Other drugs won't absorb/dissolve under the tongue but suboxone will.

That's what I'm worried about with crushing an 80 up and shoving it up there. It wasn't made for the rectum.
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Old 03-09-2006, 22:50
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Im pretty sure that all opiate drugs will have a greater more profound effect administered rectally, be careful on dosage, SWIF has had a couple of friends who have administered their usual oral dose rectally and had overdoses.. Luckily none have died but some have come close!

Rectal adminisration works because the large blood vessels in the rectum rapidly and effectively absorb the drug into the bloodstream. It is similar to insufflation in how it works however is slightly more effective due to larger blood vessels.

Maybe wait for a confirmation that it works rectally but im 90% sure it will. In how to do this, obtain a plastic syringe (no needle) and put the oxycontin into a solution of saline or water. This is then pushed up the rectum and squirted in. The onset will be quite rapid. The inital sensation will not be pleasurable and many complain of wanting to shit themselves, this will pass in 1 - 2 minutes and is of no worry. SWIF has found to most comfortable position for rectal administration is lying on the right hand side in a fetus like position.

Best of luck feel free to ask any more questions
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Old 04-09-2006, 01:01
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indeed, oxycodone will absorb rectally. use swiF's procedure to accomplish this task. use a lower dose than swiy is accustomed to with oral administration because it WILL absorb more effectively, and more quickly than with an oral dosage. swim has seen lab rats use a normal oral dose through the rectal route and not too soon afterwards, ended up vomiting because they were too high. so use utmost caution with dosage!

the suboxone just made swim think...he believes that oxycodone is at least partially bioavailable sublingually. the availability isnt too terribly high, but swim has tried putting a crushed/chewed pill in his mouth and letting it rest under his tongue a few minutes before swallowing. the onset seems to become a bit faster and absorption increased a little, in some cases he believes he felt an effect 10-15 minutes after putting it in his mouth, which is faster than if he were to have just initially swallowed it.
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Old 19-09-2006, 06:46
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Any drug that can be taken orally can be taken rectally. Rectal administration is almost as economically efficient as IVing, but for most people a much easier way to go the most out of a drug.

If SWIY crushes the pill up and disolves in water the onset is VERY rapid, too!

SWIM just rectally administered 8MG Hydromorphone and is typing to SWIY with a big grin on his face.
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