First read the wine enema thread in the alcohol section...
Now, for the next step for all you bumm-fillin' druggies out there.
Dissolve .5g of opium (real opium, not 'red rock' which is dragonsblood or 'white rock' which is frankencence.) into 3 shots of your favorite red wine and 1 shot of 80proof vodka. shake well to make sure it's all dissolved (if dirty opium and has scraps that won't dissolve filter it through a coffee filter.) also if you have a high tolorance to opiates, up the dosage a bit (swip uses 1g currently)
now with your opiated liquids, follow the instructions on your enema kit and insert the opiated liquid into your rectum. hold for as long as you would like, takes about 5 minutes to start feeling effects, swim usually hold for up to 10 minutes.... enjoy your 'deep' opium haze for the next couple hours