fumarate ??????

[psykochamane]

A friend of mine, saw "fumarate" at the end of a chemical formula.
Some one can tell me more about that (fumarate).
I found in the forum and no found nothing. except :" more stable compound" is it true?
Thanks in advance!!!
Psykochamane

[computergod]

Something to do with fumaric acid I would assume.

[entin88]

DMT fumarate is the form used in injection. i would assume this could be used the same way.

[turkeyphant]

Google is your friend: "A fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid." In this case, the fumerate of 3-[2-(isopropylmethylamino)-ethyl]-4-indolol used most likely because it is more stable than other salts and it will make the chemical less hydroscopic.

So yes, in answer to your question, it is true.

[joechip666]

If a compound is active via oral administration in the freebase and HCl forms, would the fumarate also be orally active?

[turkeyphant]

The compound I mentioned above certainly is.

[psykochamane]

and about the dosage i saw that the dosage is upper for fumarate. is it true too and how many upper on average?

[Nagognog2]

Do the chemistry: Look up what a fumarate is regards it's molecular weight. Now look up a hydrochloride. Figure out, using basic math, the difference. I'll give you all a hint - .HCl is arguably 36.5. Carbon is 12. Hydrogen is 1. Oxygen is 8.

If Hydrochloride (HCl) is 36.5, what is Chlorine?

[nostawk]

If anyone researches 4-ho-mipt fumerate please post about its stability

thanks

[psykochamane]

Thank you all

[turkeyphant]

Originally Posted by nostawk

If anyone researches 4-ho-mipt fumerate please post about its stability

As I mentioned above, it is more stable than the HCl salt.

[bearded]

Originally Posted by turkeyphant

As I mentioned above, it is more stable than the HCl salt.

Maybe so, but the 4-HO grouping of any tryptamine has troubles with oxidation, resulting in the quality of the product degrading very quickly.

[nanobrain]

Originally Posted by bearded

Maybe so, but the 4-HO grouping of any tryptamine has troubles with oxidation, resulting in the quality of the product degrading very quickly.

^you forgot to add 'when handled and stored improperly'

[bearded]

No doubt. My apologies. Strassman noted that they used the fumarate of DMT for the IV studies because it dissolves more readily in saline solutions than other salts do.