Potentiating Methylphenidate?

[Forthesevenlakes]

haha just came out of the woodwork beneath d-f.

what become of the last 10 mg?

[jmarsala]

4the7lakes:
swim will have to keep the diazebong remedy in mind for the next time he gets a stimulant crash! swim hates coming down too, but stimulants are probably the worst...

SWIM would have to disagree. Oxycontin (80mg x 10 mostly insuff. some iv, SWIMS old amout) cold-turk and/or 3-4 gram a day black tar 30% though cold-turk would be more painfull then ameth or mph possibly even psudo or meth.

The only wd's swims experinced with long-lasting uppers in SWIMS opinion like meth etc. is that when you crash, you sleep for like 2-3 days wake up hungry but no stomach for food, thirsty, di-har-re-rah and very depressed. Nothing like XTCS sucide tuesday though.

SWIM personaly h8's xtc with a passion. SWIM cannot take the transsission. Always feels like he is going to die because SWIM always has to over due things to ensure a high. So SWIM takes 3 XTC 1 swallowed, 1 crushed and put under tougn then swallowed and 1 crushed and insuffed (insuff and xtc are not only in SWIMS personal experiance a waste of $10 bucks but does not work. SWIM thinks it tastes nasty despite whatever grade or quality XTC and SWIM cannot stand to later blow his nose and blue/red/purp/whatev come out) and since SWIM mastered controlling his gag reflex's to not barf when needed (habbit now ) its always all bad. SWIM has a huge panic attack, tries to induce vomit but like SWIM previously said he cannot. SWIM then gets fresh air and is talky talky.

SWIM is very MPH'ed out and is sorry for random OT's (off topics) SWIM just really really really hates XTC, SWIM hates most uppers but MPH is an exception though is tastes freakin nast.

SWIM Also wants to state A better combo then diazebong ... temazeblunt - SWIM finds restoril (tradename for temazepam) to be more rewarding. not only for its highly solible water and insuff. rate. It gets the job done very quick and is well absorbed in man. Temazepam has a half-life of about 8 to 10 hours in plasma which is good, less side effects and minor minor minor w/d's if taken every day for a year and stoped. considering you take it the same exact time every night.

Lastly SWIM also thinks (personally) bong loads are hard core but blunts are more gangsta. SWIM gets higher off bongs but nothing could beat the taste of a nice OPTIMO PEACH Blunt cut open and filled with some of our secksy cali green (IN SWIMS Opinion, does good with any in-door blueberry, or BC. SWIM Loves dank covered in white chrystals. BC (Brit Columbia imported is always lovely like that) or dank thats extremely resiny and tar'y like blueberry)

SWIM states that he only smokes when its beautiful dank. SWIM is not a pot-head but has a script. SWIM ONLY smokes when its high THC/crystals/hairs/resin. SWIM is not an ingreat moreso SWIM lives in CALI, has his club card and only smokes the illist dank calif has to offer.

[Blur]

SWIM is in agreement with jmarsala. High-dose opiate withdrawal (especially precipitated wd) is infinitely more painful that crashing from a stim run.

[highganja99]

For SWIM potentiating in general is a no-no, Methylphenidate doesn't as SWIM is aware act on NDMA sites but the cytochrome P450* is probably involved so grapefruit juice may change the high, instead of potentiation, caffeine and tobacco can increase the stimulant experience well. SWIM SAYS THAT POTENTIATION OF DXM WITH MAGNESIUM SUPPLEMENTS IS DANGEROUS IF NOT FATAL AND SWIM STRONGLY RECOMMENDS THAT DXM USERS AVOID MAGNESIUM COMPOUNDS TOTALLY BEFORE DEXING AND EVEN WHEN CONTEMPLATING DXM USE, SWIM IS NOT BEING A PAIN HERE BUT IS TRYING TO SAVE SOME LIFES, SERIOUSLY AT LEAST MINIMALLY WAIT 48 HOURS AFTER TAKING ANY MAGNESIUM PRODUCTS BEFORE DOING DXM. Sorry for using capitals as SWIM knows how annoying it is, but SWIM feel this is a paramount statement that should not be taken lightly. competetive inhibition and potentiation is a tricky bussiness and SWIM thinks it is best avoided.

[Nicaine]

BTW, has anyone noted that L-Tyrosine can be a very uncomfortable combination with stimulants, maybe even potentially dangerous like 5-HTP + SSRI antidepressants? Dopamine/norepinephrine overload is possible, at minimum unpleasant and potentially causing symptoms like panic attacks, nausea, headache, muscle spasms, overheating, paranoia and other nasties. SWIM recommends extreme caution combining L-Tyrosine with any stimulant stronger than caffeine. By combining, he means using the two on the same day.

[~lostgurl~]

Well SWIM has read through this post and has a few ideas (grapefruit juice, tums) Does anyone have anything else to add to this list of things to potentiate ritalin? Also, what is a good small dose to take for study, not for euphoria (though that would be a bonus) SWIM wants to ration what she has to get as much done as she can.

[Lehendakari]

Originally Posted by ~lostgurl~

Well SWIM has read through this post and has a few ideas (grapefruit juice, tums) Does anyone have anything else to add to this list of things to potentiate ritalin? Also, what is a good small dose to take for study, not for euphoria (though that would be a bonus) SWIM wants to ration what she has to get as much done as she can.

What my rabbit does when doing methylphenidate (IR ritalin 10mg pills) is to let them disolve in water, they are readily soluble, he just shakes the solution and the lets the non water soluble material to sit at the bottom.

If the rabbit lets the solution dry (after removing insoluble material), the resulting powder is amazing, much more than snorting the whole pill. It's not really potentiating, its more of an extraction, but works for him.

If the rabbit drinks the water there is a much faster onset but effects are not different from ingesting the whole pill.

SWIM takes 20 mg of ritalin when studying, and then pops 10mg tablets as needed. SWIM tells me that the first dose is the most noticeable, the others are just to keep him awake and focused, so if euphoria is wanted, SWIM would take 40 mg as starting dose.

Note that nor my rabbit neither swim have used any stronger SDRI or any stronger upper. Hope this helps.

[~lostgurl~]

Thanks for the info, SWIM has 10 X 20mg Rubifen SR (methylphenidate HCL) It says on the pack "excipients q.s" not sure what that means. Would dissolving the pills SWIM has still work? If so how much water is required? What is the easiest way to remove the insoluble material? How long does it take to dry?

Also does anyone know how many tums to take and when to take them? Each chewable tablet contains 500mg calcium carbonate.... antacid.

Cheers

[Lehendakari]

SWIM has no experience with Rubifen SR (I assume it's an extended release formula) but he has tried Rubifen 20 mg tablets IR which are basically the same as the novartis brand although for SWIM Rubifen is harder in side effects and not too much of euphoria. He definitely likes ritalin better.

The term "q.s." means adding a quantity sufficient to achieve stated function, e.g., to bring a solution to the desired volume (i.e., 100%).
Rubifen tablets containing 20 mg methylphenidate HCl weight about 30-35 mg (my scale isn't very good)

I guess that making a fine powder would release MPH from the coating element but don't know.

[~lostgurl~]

SWIM tried potentiating methylphenidate by drinking 1 glass of grapefruit juice half an hour before injesting 2 X 20mg Rubifen SR pills, but the effect seemed weaker than her dose the day before of 60mg Rubifen SR. SWIM will give it another go but from this one experience she would say that grapefruit juice does not potentiate methylphenidate, though she is not sure if it has anything to do with her pills being 'slow release'.

[geophagus]

Originally Posted by ~lostgurl~

SWIM tried potentiating methylphenidate by drinking 1 glass of grapfruit juice half an hour before injesting 2 X 20mg Rubifen SR pills, but the effect seemed weaker than her dose the day before of 60mg Rubifen SR. SWIM will give it another go but from this one experience she would say that grapefruit juice does not potentiate methylphenidate, though she is not sure if it has anything to do with her pills being 'slow release'.

It has nothing to do with your pills being 'slow release,' however, it very likely does have to do with the citric acid in the grapefruit juice that SWIY consumed.

It's best to avoid most high acid foods for best results concerning absorption and normal elimination of methylphenidate. To potentiate methylphenydate it would be advised (in addition to avoiding acid rich foods) to comsume sodium bicarbonate, and if that's not an option then calcium carbonate would be SWIM's next choice.

[ssxx27]

SWIM likes 20mg Ritalin on an empty stomach for a nice peaceful alertness.

[dukewizard1986]

SWIM said that L-tyrosine is converted in the brain to l-dopa then to dopamine. This increases dopamine availability/release and will surely potentiate the effects of any substance that releases or recycles dopamine. Also SWIM mentioned that l-phenylanine which is a precursor to l-tyrosine is also converted to dopamine and *phenethylamine (the body's natural speed among other things).

[dukewizard1986]

SWIM also mentioned that their are certain vitamins that assist in the conversion of l-tyrosine to dopamine. SWIM mentions Vitamin B-6. Toss this in with the l-tyrosine and or l-phenylanine and the speed will reach its full potential.

[highganja99]

SWIM tried using Sodium Bicarbonate to potentiate Ritalin, He mixed at least several tablepoons of Sodium Bicarbonate in a pint of water and drank it, an hour later he snorted 20mg ritalin and had a stronger effect than normal, the next day he repeated making the drink and took 20mg oral and it had a stronger effect than normal, although this method worked it is not recommended due to the amount of Sodium Bicarbonate that is ingested.