4-AcO-DMT

[BlueMystic]

Please post info about 4-ACO-DMT here.
Can anyone add information about:

• names / synonyms
• molecule
• dose
• duration
• side effects
• have there been any reported incidents with this compound?
• since when has this research chemical been available?
• legal status
• stability of the molecule / compound

Experiences with 4-ACO-DMT should be posted here: 4-AcO-DMT trip reports
These documents about 4-ACO-DMT are in the file archive

Also see this threads:
What dose of 4-aco-DMT is best comparable to 1/8th of an ounce of good dried shrooms?
Abdominal pains from 4-acO-dmt?
4-AcO-DMT Legal in the USA?

Our members list varying dosage & duration. Dosage ranging from 10 - 30 mg. Duration ranging from 4 - 8 hours.
Most list good effects around 15 -20 mg 4-ACO-DMT. 10 mg 4-ACO-DMT seems a good beginners dose. 30 mg is described as scary & very intense.

__________________________________________________ __________________

Anyone have any feedback or documents on this one? SWIM sas been interested in it for a while and is looking at trying it in the near future. There is little out there about this one. So any and all info would be appreciated.

[Nagognog2]

Looks like it would resemble psilocin in effect, though not quite as potent. The going argument is it would break down into psilocin before being active. Quite likely a schedule I substance in the USA et al. Probably would have traces of the 4-OH present, giving it a positive test for psilocin as well.

Do have your monkey write up a report. Looks very interesting.

[BlueMystic]

Looks like it would resemble psilocin in effect, though not quite as potent. The going argument is it would break down into psilocin before being active.

That's what SWIM's been thinking but wasn't sure about the potency factor.

I had to spank my monkey for being a bad boy recently. As soon as he recovers I'll have him do just that.

[illuminati boy]

If I had to make an estimate extrapolating from other 4-HO / 4-AcO pairs I would guess that it probably has more of a latency before effects hit. It is probably 50 – 90% the potency of it’s 4-HO cousin, but could have a duration of effect that is extended a few hours. Effects could be more gradual / smooth on the come-up. The compound may be more likely to cause more ‘body energy’ / tremors.

4-HO-MiPT / 4-AcO-MiPT is probably the best / nearest set of comparators. Judging from them; probably a much smoother come-up, a notably longer duration, and possibly a notable decrease in milligram to milligram effects even taking the different molecular weights into account.

Pure guesswork though…

I B

Reputation Comments on this post:

VERY informative and accurate theory. Thanks for the information! :)

[rxbandit]

Originally Posted by BlueMystic

Anyone have any feedback or documents on this one? SWIM sas been interested in it for a while and is looking at trying it in the near future. There is little out there about this one. So any and all info would be appreciated.

I'm also looking for a dose reference.

Erowid reports a "strong" dose of psilocybin as between 8-20mgs. That's quite a large range.

I've searched around, but I haven't been able to find a better reference. The only other things I've come across are low doses of psilocybin administered during trials in the 1960's, but it didn't sound as if they were aiming to achieve the full psychedelic effect with those doses.

I'm also aware that Sandoz produced 10mg psilocybin tablets, but again, I could not find any other information to describe the effects of their 10mg tablets.

[Nagognog2]

In the early 60's, the dosage range employed with psilocybin by such "researchers" as Leary, Alpert, and Metzner was 10 - 60mg. If that helps.

[sg43]

SWIM read on another forum a source has finnaly appeared for this one, any experiences yet?

[trip.more]

swim is wondering what the doses look like?Would it be the same as psilocin?

[dondante]

I agree with IB's prediction. It also depends on the salt. I did this a while ago based on the shroomery's dosage of psilocin and just added psilocetin fumarate on there since that's what I've got. The salt is pretty heavy so the dosage is quite a bit higher. This is obviously a very rough estimate, but better than erowid's 8-20mg for a strong dose of psilocybin.

Level ..... Psilocin(mg).... Psilocetin fumarate(mg)
1................... 4 ...................5
2....................6 ...................9
3 ..................11 ..................16
4 ..................17.................. 25
5 ..................22 ..................34

Hope that makes some sense. Damn formatting.

Reputation Comments on this post:

	Good answer
	extremely useful info!
	Excellent Thank you very much :D

[sg43]

SWIM may have some of this compound on the way, he will write a report when it's assayed, also does anyone know if the fumarate will still degrade due to humidity?

[rodent]

Same here... SWIM is expecting his very soon and will report his experience.

I believe the fumarate salt is supposed to be more stable though, I am basing this on a failing short-term memory...

A google search turned up... what were we talking about again?

[MadShroomer]

This is Psilocin notice the 4-ho at the top left...

This is Psilocybin, notice the complex Phosphorus bond at the upper left...

Now ignore the Di-Isopropyl bonds in the upper right and take that Acetoxy bond and stick it on the 4-ho on Psilocin and walllah...

Reputation Comments on this post:

	nicely done
	love the pictures and i haven't seen this molecule in a 3d picture yet so it was cool to see
	excellent illustrations, really added to the thread

[radiometer]

Let's hope the "synthetic psilocybin/legal mushrooms" dumbass marketing cadre don't get their hands on this one.

[MadShroomer]

SWIM is waiting to hear back from SWIM about that experience and SWIM hopes to have one soon...

[nanobrain]

useful info as always from our illuminated colleagues, but the other half thread is an 'ooh, ooh, i want some too'.

so if you the reader share the identity of the writer of such missives, cut it out. as in friggin now. put desire back in pants. reread the rules, which in turn will be updated shortly and shall be of a stricter nature indeed.

alles klar?

[radiometer]

I'm wondering what would be the result of combining 4-AcO-DMT with mushrooms (in suitable total quantity of course).


Raven: 1) please clear out some PM space! You're full!!

and 2) I know nothing whatsoever about IV doses, did you mean someone else?

[raven3davis]

okay pms cleared....and SWIM was asking radio879 about the IV doses SWIM is seriously considering doing a large IV dose once he gets more experience with this chemical. He has heard little discussion about the actual dose so he just wanted to probe radio879 for possible details.

[MadShroomer]

We'll SWIM can't wait to try this one. SWIM has a 0.01g scale and is planing to weigh out 10mg dose's. SWIM plans to experiment with freebase'n out of lightbulb (Fear 'n Loathing style ;P) as well as snorting. Strang that it doesn't "burn" like most other HCL salts.... Maby its a differen't salt... hrm?
Thanks for the rabbit reply's all Anyone got anything else they'd like to ad? SWIM doesn't like needles and the only thing SWIM has ever injected was ADDRENACROME (pink addrenaline) a while ago and it was just Intra Muscular (in left shoulder). SWIM is over that though after drinking 3 viles and feeling just like Mr. HST in Fear and Loathing, crawled into bath tub but only mild relief followed by 18 hours sleep (SWIM doesn't remember much except being DELIERIOUS and not being able to tell if the lightning flashes in the room were real or not, plus feeling all shaky and on fire, did feel the way it was shown in the movie...most unpleasant b/c SWIM "Took to much man, too much").

[raven3davis]

Most, if not all of the 4-aco-dmt circulating is 4-aco-dmt fumurate, which should be more stable than other forms. This is important since the 4-aco-dmt can decompose into a scheduled compound. SWIM thinks this is a move by the chemists to cover their ass, and partially to cover our asses. The fumurate is said to be very stable and lab results have shown a sample to contain 0% 4-ho-dmt.

Reputation Comments on this post:

good job

[MadShroomer]

Ok here is my Photoshop masterpiece
4-aco-dmt

[Nagognog2]

I find your description of "addrenacrome" highly suspect. Perhaps it was just adrenaline with a small amount that had oxidized. But this belongs elsewhere:

http://www.drugs-forum.com/forum/forumdisplay.php?f=37

[MadShroomer]

SWIM was pleasently surprised by a google search today that uncovered this ....
http://en.wikipedia.org/wiki/Psilacetin
Notice they spell "Psilacetin" out how informative )
some more links...
http://www.erowid.org/references/ref...ltryptamine%22
http://www.bluelight.ru/vb/showthrea...ght=4-AcO-DMT/

[radiometer]

That Wiki is MorningGlorySeed's work, and he's looking for contributors.

[MadShroomer]

SWIM thinks this compound is AMAZING,
does take 2.5 to 3h to peak but WHAT an AMAZING peak it is. Insuffilation is SWIM's prefered method of injestion as this provides an initial "rush" effect followed by a slow and insanely mild come up followed by a pleasant and extended comedown when compared to P.Cubensis.
SWIM has tried I.V. dose of 10mg and would have rather snorted it as SWIM found out the initial rush was INTENSE AS ALL CRAP but the peak was less "Magical" and much shorter in duration.

SWIM thinks that the acetyl bond provides this molecule with the ability to pass directly through the blood brain barrier as it does with di-acetyl-morphine.
SWIM believes that once inside the blood brain barrier it is converted into 4-ho-dmt and somehow SWIM feels that the peak on ~35mg was an insane breakthrough with much more lucidity and ego dissolution similar to a high dose of LSD or DMT. Overall SWIM rates this at an Astounding ++++ compaired to other RC's SWIM has tried. SWIM believes this to be far supperior to its naturally occuring cousins 4-PO-DMT and 4-HO-DMT (relatively speaking its broken down into Psilocin in the body but that magical acetyl bond protects and insures its mission of reaching the central kingdom after passing through the body).

SWIM usually only does a new RC once to get a "taste" but found out with this molecule a 6 day "benge" followed...
Day 1: ~10mg insuffilated by SWIM and SWIM's friend. Initial "rush" effect was noted immediately followed by a mild 'shroom experience equivalent to 1.0-1.5g dried P.Cubensis.
Day 2: ~30mg insuffilated by SWIM and SWIM's friend (This was as high as SWIM got, best peak and SWIM's friend agrees). A definate ++++ experience.
Day 3: ~15mg insufilated by SWIM and SWIM's friend, this time only 3/5 the intensity of day 1 experience (0.5 - 1.0g P.Cubensis).
Day 4: ~20mg insufliated by SWIM and SWIM's friend, this time tolerance has increased greatly as effects were comparative to 10mg on day 1.
Day 5: ~10mg@T-0h. Then ~10mg@T+0.5h and another ~10mg@T+1.0h. This repeated doseing led to 3 distinct peaks arriving one after the other in 30 minute increments, according to SWIM and SWIM's friend and at the T+2.5h point SWIM reaches:
V___V___V___V___V___V
Day 6 (past midnight from day 5 dose): ~20mg is insuffilated by SWIM and SWIM's friend. SWIM starts to watch "Charlie and the Chocolate Factory" 2005 Johny Dept movie and is definately "feeling" it like on day 2 but still not as intense a peak even though SWIM and SWIM's friend did more than 3 times the Day 2 dose. SWIM realizes that a break is needed as SWIM's tolerance has spiked.

Reputation Comments on this post:

	Good contribution of info regarding this compound
	nice research done, man!
	Thnks for sharing.

[MadShroomer]

This is on another forum (edit:delete) but SWIM felt it should go here, the guy SWIM's quote'n is on this board as well ... at least SWIM thinks so...

Originally Posted by Dondante

^^Glad you enjoyed yourself. Six days though ... perhaps a little excessive?



The long climb to the peak with intranasal administration makes me even more confident that the 4-aco-dmt has at least some trouble passing the BBB. If it could pass easily, you would peak earlier. I bet if you insufflated 4-ho-dmt, you'd peak pretty damned fast. Anyway, thanks for the report MadShroomer.

Actually,
SWIM DID experience an initial RUSH and this is believed to be the result of the 4-acetyl bond, wich is the same bond that turns Morhpine into Heroine (makes it more effective/addictive BECAUSE the acetyl bond enables it to pass VERY quickly through the blood/brain barrier). But don't take my word for it...check it

According to Alexander Shulgin, "In the case of psilocybin to psilocin, this saponification is essential for activity, as the phosphate ester is far too polar to get across the blood-brain barrier. But this problem need not exist with the acetate ester. I have explored the 4-hydroxy-DET but I am more familiar with the 4-hydroxy-DIPT. It is of a rather rapid onset implying possible absorption directly from the stomach. However, in a group study with the corresponding ester 4-AcO-DIPT, we felt that it had an even faster onset and perhaps a increased potency. This would suggest that it might be considered an active drug in its own right rather than simply a precursor to the active drug 4-HO-DIPT."

This quote came from here:
http://www.erowid.org/chemicals/4_ac...article1.shtml

So the initial "RUSH" is the molecule entering the central kingdom, then the body does what ever and turns it into a much more potent tryptamine (this would be 4-ho-dmt but might be oxidized to a very quinonic product that is unknown).

Read the above link to the article its FACINATING!

Reputation Comments on this post:

Read the rules, linking to other forums is not allowed