tramadol and mda

[primal440]

hello, ive read that taking SSRI antidepressant totally blows the MDMA experience if taken during treatment and that one has to wait several months to clear up the body to feel the proper MDMA experince. I wanted to know if this principle applies also to MDA and Tramadol which is a mild-SSRI and has a half-life of 6-12 hors, because swim plans on using MDA one day of this week and since swim doesnt want to ruin the experience would like to know if it has to stop the tramadol use a day before the experience (hopefully) or a month. thanks in advance.

[Nagognog2]

Tramadol should be allowed at least a week to both clear the body, and for the body's serotonin levels to restore, before attempting any excursions on MDMA, methylone, MDE, etc.

The half-life in the body does NOT take into account the time needed for the changes made to revert to normal.

[primal440]

yeah i was taking into account the serotonin factor but i never considered serotonin being so relevant to the MDA experience, I mean, at least to me that happy happy joy joy rush aspect is a minor one and I think less important and practically inexistent when compared to the MDMA course of action, I say this with almost none scientifical background but i know that when SWIM takes MDA he doesnt experience the hard come down of MDMA or Amph, and that tells you something I think. Or maybe im wrong, the only thing I know is that SWIM once took tramadol and 10 hours later an unknown quantity of MDA and experienced the drug, although in a more subtle manner and with not that much of a rush but SWIM doesnt know if this was because of the tramadol or if it was because of a small dose, SWIM infers it was a small quantity because the chemical flavor did not linger for too long.
are you sure nagognog about letting off the tramadol for at least a week before trying the MDA or maybe thats for taking a little caution?
After all, when taking tramadol between days, effects dont seem to differ much, nor in the opiate or the SSRI aspect, but i know that with serotonin you gotta be more careful (although SWIM isnt into taking 5-HTP, etc)

[Nagognog2]

Granted MDA is not as directly linked to serotonin as MDMA etal, but about a week is what is needed to undo the damage (Bongo loathes tramadol, LOL) that tramadol does to one. Less than might be okay for MDA, but a week would make sure of this. Besides - this isn't a horse-race, now is it?

Bongo did a study on tramadol's SSRI effects/duration some time back due to problems a friend was having. It was from this that he determined that a week was needed to fully clear the cobwebs in one's cranium's geraniums. Though I've yet to see any formal study of this, yet, in the medical literature. Anyone?

[primal440]

ok helps for clearing that out, i wasnt expecting such a good response, i can see you're very knowledgeable. i can also see you loathe tramadol as ive posted other questions regarding its dual effects and there's always a drop of disgust on tramadol in your questions hehehe. im really interested in that study bongo did on the SSRI effects, how could you discern the week thing with such a subtle factor??? please respond, and if you want/can put on some of the results off that informal study bongo did.

[WrtngCocaineTutorial]

Just a word of advice: if a person is depressed, he/she is in the "group" which have the absoulte highest potential of becoming an addict

[lilredhead5]

What about other anti-depressants, such as EFFEXOR and LAMICTAL? Would the MDMA have little or no effect if swim were to try the MDMA and swim were taking, let's say, 150 mg of EFFEXOR and 100 mg of LAMICTAL daily, with a 50mg dose of TRAZADONE at night? Or would swim be wasting time and money on the MDMA/XTC ?

[Veeg]

Originally Posted by primal440

[snip] I wanted to know if this principle applies also to MDA and Tramadol which is a mild-SSRI ...

Are we talking about Tramadol Hydrochloride? If so, I thought this was an opioid based pain-killer, I would be surprised if it had any SSRI activity at all?

[Abrad]

Tramadol is an opioid but does have SSRI properties.

[Veeg]

Originally Posted by abrad84

Tramadol is an opioid but does have SSRI properties.

Thank you, I had no idea about Tramadol being a mild SSRI. Slighly off topic, my pet cat has occasionally taken Tramadol mixed with a little alcohol as a sleep aid.